Alex Tarnava

• CEO at H2 Therapeutics

The sustainable development goals (SDG) of the UNO would be difficult to achieve without prevention of non-communicable diseases (NCDs). Western diet and lifestyle, which are major risk factors of NCDs, are known to cause oxidative stress and decrease in production of molecular hydrogen in the intestines which leads to a decline in endogenous antio...

Diet and lifestyle choices, notably the Western-type diet, are implicated in oxidative stress and inflammation, factors that elevate the risk of cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). In contrast, the Mediterranean of diet, rich in antioxidants, appears to have protective effects against these risks. This article highli...

Study Objectives Sleep loss contributes to various health issues and impairs neurological function. Molecular hydrogen has recently gained popularity as a nontoxic ergogenic and health promoter. The effect of molecular hydrogen on sleep and sleep-related neural systems remains unexplored. This study investigates the impact of hydrogen-rich water (H...

Background Although several studies have shown that the Coronavirus Disease 2019 (COVID-19) lockdown has had negative impacts on mental health and eating behaviors among the general population and athletes, few studies have examined the long-term effects on elite and sub-elite athletes. The present study aimed to investigate the long-term impact of...

Background Although several studies have shown that the Coronavirus Disease 2019 (COVID-19) lockdown has had negative impacts on mental health and eating behaviors among the general population and athletes, few studies have examined the long-term effects on elite and sub-elite athletes. The present study aimed to investigate the long-term impact of...

Skeletal muscle atrophy is associated with poor quality of life and disability. Thus, finding a new strategy for the prevention and treatment of skeletal muscle atrophy is very crucial. This study aimed to investigate the therapeutic potential of hydrogen-rich water (HRW) on muscle atrophy in a unilateral hind limb immobilization model. Thirty-six...

Background: Recently, chronic lung diseases have been found to be associated with marked inflammation and oxidative stress, which leads to fibrosis in the lungs and chronic respiratory failure. This study aims to determine if hydrogen-rich water (HRW) can enhance oxygen saturation among patients with chronic lung diseases. Methods: Ten patients...

The sustainable development goals(SDG) of the UNO would be difficult to achieve without prevention of metabolic diseases and other non-communicable diseases (NCDs). Western diet and lifestyle, which are major risk factors of NCDs, are known to cause oxidative stress and decrease in production of molecular hydrogen in the intestines which leads to a...

There is evidence that behavioral risk factors such as western type diet, and life style can predispose to oxidative stress, deficiency in antioxidant status, hyperglycemia, dyslipidemia and increase in inflammation in tissues of various organs: beta cells of the pancreas, LDL receptors in the hepatocytes, endothelium, neurons, osteocytes and gut....

Background: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in the world. Tumor removal remains the preferred frontline treatment; however, effective non-surgical interventions remain a high priority. 5-fluorouracil (5-FU) is a widely used chemotherapy agent, and molecular hydrogen (H2) has been recognized for its antio...

Over the last century there have been significant advances in medical procedures pertaining to geriatrics and emergency medicine, resulting in significant average life span extensions in most developed nations. Although the life span has been significantly extended, the rate of chronic non-communicable diseases (NCDs) has risen, largely owing to th...

Administration of molecular hydrogen dissolved in water to patient with COVID‐19‐like symptoms may improve oxygen levels and exercise capacity. Administration of molecular hydrogen dissolved in water to patient with COVID‐19‐like symptoms may improve oxygen levels and exercise capacity.

COVID-19 is associated with respiratory failure and subsequent hypoxia. New therapies that reduce hypoxia are urgently needed. Molecular hydrogen (H2) therapy may reduce inflammation, oxidative stress, and hypoxia. This case report suggests that hydrogen-rich water (HRW) increases oxygen saturation increase exercise tolerance in a patient with COVI...

ABSTRACT Colitis is an inflammatory condition of the bowels associated with abdominal pain, diarrhea, fatigue, and fever. Its etiology is multifactorial but related to the overproduction of inflammatory and oxidative mediators. There is currently no cure for this disease, and drugs used to manage it often have deleterious side effects. H2 is recogn...

Background: Traditional treatments of soft tissue injuries (STIs) and some musculoskeletal injuries (MSK-Is) involves therapies such as the RICE protocol, which consists of rest, ice, compression and elevation for several days following acute trauma. Designed to improve comfort and reduce pain following traumatic injury, questions exist on the effi...

Molecular hydrogen (H2) has demonstrated therapeutic properties across numerous models. To date, the mechanism underlying the beneficial responses to H2 exposure remains elusive. The initial hypothesis that molecular hydrogen acts as a direct, selective antioxidant in vivo does not reconcile models where H2 has shown to increase oxidative stress, n...