Alen Salerian

• salerian neuroscience and pain center

Background: It has been suggested that life began from sterile organic matter and the first microorganisms have evolved to complex multicellular organisms. Also, it has been hypothesized that some Infections may derive through diverse pathways independent of contamination or oviposition. Objective: The aim of this study is to demonstrate that micro...

Blow ies (Calliphoridae -Diptera) , crucial participants In the mammalian decomposition and have been known as the causative agents of myiasis by laying eggs on human or other vertebrates' necrotic or living tissue . This study- prompted by scientic observations that blow y behavior is strongly mediated by visual cues and not by olfactory cues-...

This study advances a previous hypotheses, “Human body may produce bacteria “and proposes that some infections are generated by human stem cells which differentiate to bacteria and fungus. Evidence consistent with the hypotheses that” Stem cells may differentiate to microorganisms” include studies suggesting that Christensenellaceae are heritable,...

This study presents evidence to propose that some human infections may derive Independent of contamination by invading pathogens. Diverse data suggest multiple pathways Independent of contamination may generate human infections. For instance, the first microorganisms that emerged from lifeless organic matter 3.6 billion years ago indicated transfor...

This correspondence inspired by recent NASA plans for two astronauts to spend 6.5 days on the moon-reviews the radiation effects upon the Apollo astronauts who traveled to the moon and back from 1969 to 1972.

This paper advances a previous hypothesis “Human body may produces bacteria”, and proposes that some infections may be endogenous. It has been demonstrated that the Christensenellaceae, a family in the phylum Firmicutes, is heritable suggesting that human genetic material and gut bacterial material are related and human cells may generate some gut...

“Human body may produce bacteria” proposes that human body may produce bacteria and represent an independent source of infections contrary to the current paradigm of infectious disorders proposed by Louis Pasteur in 1880. The following observations are consistent with this hypothesis: A. Bidirectional transformations of both living and nonliving th...

Background: This study reviews physician and patient injuries from the practice closures of four individual practitioners in Washington DC. Method: Retrospective review of patient records, vital statistics and relevant administrative – legal files related to the office closures. Results: Approximately 1000 patients were affected by the office closu...

This study reviews the publications about the Sandy Hook massacre allegedly committed by an autistic man with history of Asperger’s disorder. We systematically reviewed the news about the Sandy Hook massacre. Despite the publicly available scientific evidence consistent with the inaccuracy of the alleged massacre the news media has continued to por...

This study reviews the validity of a public perception promoted by Centers Control that prescription pain medications have contributed to an epidem deaths and illicit use of heroin. No scientific evidence has been found to su causative link between prescription pain medications and an epidemic of deaths and illicit use of heroin. The study results...

Addictive potential of a substance may be predicted on the basis of a mathematical formula of A = P + R with A representing the addictive potency P representing punishment potency and R representing reward potency. The review suggests 2 principal influences reward and punishment play the crucial role of defining the addictive potency of a substance...

Endorphins and endorphin agonists play a crucial role in the neuromodulation of mood, anxiety, pain and addiction. Review of clinical studies seem to elucidate possible protective role of opiates against neurodegeneration and premature death. The historical, biological, experimental, clinical and neuroimaging data strongly support the potential pro...

Objective: We reviewed neuroimaging evidence to determine whether prefrontal cortex is endowed with unique properties that mediate both normalcy and psychiatric illness. Method: Evidence based upon clinical observations and neuroimaging studies were reviewed. Results: The cumulative evidence -based upon clinical and neuro imaging evidence- sugges...

Endorphins and endorphin agonists play a crucial role in the neural modulation of mood, anxiety, pain and addiction. Recent studies have elucidated the crucial mechanism of enhancing prefrontal cortex influence and dampening limbic and sub cortical influences in depression and remission consistent with the biological profile of endorphin agonists....

This retrospective study reviews 49 patients- one year with opiate and one year post treatment discontinuation - treated at a private outpatient psychopharmacology center. This retrospective study reviews the health status of 398 patients with two distinct subgroups, 17 local and 32 out-of-town patients. Results revealed significant rise in fatalit...

This study offers evidence to suggest that both normalcy and psychiatric illness are sensitively dependent upon prefrontal cortex function. In general, the emergence of psychiatric symptoms coincide with diminished influence of prefrontal cortex function. The mediating influence of prefrontal cortex may be independent of molecular and regional brai...

We review the evidence for relationships between metabolic activity of cortical, subcortical and limbic brain regions in depression and the efficacy of antidepressant agents. The influence of these regions can be described by an algebraic equation, N=H/(M+R), where N represents a homeostatic level of executive function, H represents prefrontal (BA...

"President John F. Kennedy's death was a neurotoxin-assisted homicide" is the hypothesis of this study. A review of medical evidence demonstrates evidence of a neurotoxin-assisted homicide. The convergence of three independent actions, or the signature traits of a neurotoxin-assisted homicide- the emergence of neurological signs consistent with a n...

This hypothesis named Salerian Addictive Potential (SAP) suggests that the addictive potency of any substance may be calculated with an algebraic equation of A=E/T(max)xt(1/2), where A is the addictive potency, E represents the euphoric potency, T(max) is the time to reach peak plasma concentration, and t(1/2) is the plasma elimination half-life. T...

Thermodynamic laws and complex system dynamics govern brain function. Thus, any change in brain homeostasis by an alteration in brain temperature, neurotransmission or content may cause region-specific brain dysfunction. This is the premise for the Salerian Theory of Brain built upon a new paradigm for neuropsychiatric disorders: the governing infl...

Reduction of core body temperature has been proposed to contribute to the increased lifespan and the anti-aging effects conferred by caloric restriction in mice and higher primates. Cooler biologically compatible core body temperatures have also been hypothesized to combat neurodegenerative disorders. Yet, validation of these hypotheses has been di...

This paper proves that President Kennedy's postmortem examination is a sham. The sham nature of the presidential autopsy is based upon several findings incompatible with human anatomy, practice of medicine and Newton's second law "an object acted upon by a constant force will move with constant acceleration in the direction of the force". We review...

Lowering core body and brain temperature has been shown to be beneficial for multiple sclerosis, cardiovascular accidents, traumatic brain injuries and myocardial infarction. Svante Arrhenius' rate law governs human thermoregulation and all biochemical reactions including complex chemical processes involved in mood disorders. We reviewed the studie...

Scientific evidence suggests the critical role of temperature in regulating three mechanisms contributing to cellular damage: Oxidative stress, oxygen demand overload and inflammation. In this article, we propose that the Arrhenius rate law has a profound impact on aging and a variety of neurodegenerative disorders including Alzheimer's disease, an...