Aleksi Hamina

Aleksi Hamina
University of Oslo · Norwegian Centre for Addiction Research

Doctor of Pharmacy

About

17
Publications
1,554
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110
Citations
Introduction
I am a PhD of Pharmacy studying opioid use and related outcomes from Nordic healthcare registry data.

Publications

Publications (17)
Preprint
Full-text available
Previous studies have defined long-term opioid use in varying ways, decreasing comparability, reproducibility and clinical applicability of the research. Based on recent systematic reviews, we aimed to estimate long-term opioid use defined as use persisting more than three months using one of the Nordic prescription registers. We used the Norwegian...
Preprint
Previous studies have defined long-term opioid use in varying ways, decreasing comparability, reproducibility, and clinical applicability of the research. Based on recommendations from recent systematic reviews, we aimed to develop methodology to estimate the prevalence of use persisting more than three months utilizing one of the Nordic prescripti...
Article
Full-text available
Bakgrunn: Opioider for behandling av langvarige smerter kan forskrives på blå resept, men bør ikke brukes samtidig med andre vanedannende legemidler. Hensikt: Å undersøke bruk av opioider på blå resept i perioden 2009-2019, samt å studere bruk av andre vanedannende legemidler (benzodiazepiner og z-hypnotika) blant dem som fikk opioider på blå resep...
Article
Full-text available
Background: Prescribing opioids for children and adolescents should be reserved for advanced life-limiting diseases and moderate-to-severe acute pain. Pediatric codeine use is discouraged by several authorities, but the effects of these recommendations are not fully known. We investigated opioid utilization trends among 0-18-year-olds and characte...
Article
Full-text available
Frailty is a geriatric condition associated with increased vulnerability to adverse drug events and medication-related harm. Existing clinical practice guidelines rarely provide medication management recommendations specific to frail older people. This report presents international consensus principles, generated by the Optimizing Geriatric Pharmac...
Thesis
Full-text available
Alzheimer’s disease (AD) is the most common cognitive disorder. Among persons with AD as well as in older persons in general, pain is an important factor impairing health and limiting the quality of life. Analgesics are the most frequently used treatment for pain, but little is known about their use among persons with AD. This thesis aimed to study...
Article
Full-text available
Background Hip fractures are common among persons with Alzheimer’s disease (AD), but problems in pain assessment may lead to insufficient analgesia after hospitalization. Objective We investigated the prevalence of opioid use in the 6 months after discharge from hospital care due to hip fracture among community-dwellers with and without AD. Setti...
Article
Background: Pneumonia is a common cause for hospitalization and excess mortality among persons with Alzheimer’s disease (AD), but little research exists evaluating drug use as its risk factor. Objective: We investigated the association between opioid use and hospital-treated pneumonia among community dwellers with AD. Methods: This study was par...
Article
Objective To determine the prevalence of concomitant use of benzodiazepines and opioids among community‐dwelling older people with or without Alzheimer's disease (AD). An additional aim was to describe the factors associated with prolonged concomitant use, and the most commonly used combinations of these drugs. Methods This study utilized data fro...
Article
The objective of this study was to investigate whether incident opioid use is associated with an increased risk of hip fractures among community-dwelling persons with Alzheimer's disease (AD), and to assess the association in terms of duration of use and opioid strength.Among community-dwelling persons with AD diagnosed in 2010-2011 (N=23,100), a m...
Article
Background We analyzed the impact of opioid initiation on the prevalence of antipsychotic and benzodiazepine and related drug (BZDR) use among community-dwelling persons with Alzheimer's disease (AD). Methods We utilized the register-based Medication use and Alzheimer's disease (MEDALZ) cohort for this study. We included all community-dwelling per...
Article
Objective: We investigated whether opioid use, duration of use, and cumulative dose are associated with an increased risk of Alzheimer's disease (AD). Methods: A Finnish nationwide nested case-control study, MEDALZ, included 70,718 individuals with AD and up to four age-, sex-, and region of residence-matched comparison individuals. The cohort i...

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Projects

Project (1)
Project
The overall objective of the project is to help opioid prescribers optimize treatment for chronic pain patients to reduce pain without escalating opioid treatment, to prevent adverse consequences of opioid treatment, and to increase patients’ quality of life - to ultimately prevent an opioid epidemic in Norway. To achieve our main objective, we will increase knowledge about pain patients and their opioid prescribing doctors, as escalating opioid use develops in their interaction. We will use a multifaceted approach to gain new knowledge on several levels of long-term opioid use.