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Associate Professor Redwood works at the Univeristy of Western Australia. He is a Principle Research Fellow working on neoantigen vaccines for cancer immunotherapy. Dr Redwood is also the head of the Vaccines and Viral Immunity Group which focuses on cytomegaolovirus (CMV) immune evasion and genetics. A particular focus of this group is the use of CMV as a vaccine vector for multiple infectious agents and as a vector for cancer immunotherapy.
-Drug Hypersensitivity is a "Type B" Adverse Drug Reaction (ADR) which has high global morbidity and mortality, and are immunologically-mediated. -Different drugs can have different mechanisms in which they initiate a hypersensitivity reaction (Hapten, pi model and/or altered peptide model). -Gaining a better understanding of the immunological requirements needed for ADR to occur will aid in understanding the relevant mechanisms, and help clinically for treatments which have known risk factors (ie. HLA alleles) with low positive predictive values.