Alberto Manuel Torres-cantero

Alberto Manuel Torres-cantero
University of Murcia | UM · Department of Public Health Sciences

Medical Doctor, MPH, DrPH, PhD

About

144
Publications
23,223
Reads
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2,768
Citations
Citations since 2016
67 Research Items
1664 Citations
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300
Additional affiliations
September 2004 - December 2015
University of Murcia
Position
  • Professor of Public Health and Preventive Medicine
Education
September 1986 - June 1991
Harvard University
Field of study
  • Epidemiology, Population Sciences and Public Health
September 1985 - June 1986
Harvard University
Field of study
  • Epidemiology and Public Health

Publications

Publications (144)
Article
Background: Immune signatures at birth could be associated with clinical outcomes and will improve our understanding of immunity prenatal programming. Methods: Data come from 235 newborns from the cohort study NELA. Production of cytokines was determined using Luminex technology. Associations between cytokine concentrations with sex and season o...
Article
Objectives To develop and evaluate a new highly sensitive assay to detect IgG anti-SARS-CoV-2 RBD in saliva samples. Methods A two-step sandwich type immunoassay based on the amplified luminescent proximity homogeneous technology was developed and an analytical validation was performed. As a part of this validation, the influence of factors, such...
Article
Full-text available
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2), is usually associated with a wide variety of clinical presentations from asymptomatic to severe cases. The use of saliva as a diagnostic and monitoring fluid has gained importance since it can be used to investigate the immune respon...
Article
Full-text available
Endocrine disrupting chemicals (EDCs) set a public health risk through disruption of normal physiological processes. The toxicoepigenetic mechanisms of developmental exposure to common EDCs, such as bisphenol A (BPA), are poorly known. The present study aimed to evaluate associations between perinatal maternal urinary concentrations of BPA, bisphen...
Article
Background There has been a decrease in sperm concentration in recent years. Concurrently, there were important dietary changes, including an increase in sugar-sweetened beverage intake (SSB). The relation between SSB and male reproduction functions in humans are barely described in the literature. Methods Cross-sectional study with 209 participan...
Article
Full-text available
Objective: The World Health Organization declared the global SARS-CoV-2 infection a pandemic on March 11, 2020. The objective of this paper is to present its impact in terms of physical and mental health 22 months later. Method: We have reviewed results from published meta-analysis and systematic reviews, and some individual articles on specific...
Article
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Background: Primary prevention strategies for asthma are lacking. Its inception probably starts in utero and/or during the early postnatal period as the developmental origins of health and disease (DOHaD) paradigm suggests. Objectives: The main objective of Nutrition in Early Life and Asthma (NELA) cohort study is to unravel whether the followin...
Article
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Anthropometric assessment during pregnancy is a widely used, low-technology procedure that has not been rigorously evaluated. Our objective is to investigate fat mass distribution during pregnancy by examining changes in anthropometrics measures, in order to evaluate the reliability of these measures. An observational, longitudinal, prospective coh...
Article
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Research question : Have women with polycystic ovary syndrome (PCOS) a different fat intake pattern? Design : A case-control study of 276 women between 20 and 35 years old from the Region of Murcia (Spain). Cases (n=121) were attended at Department of Gynecology and Obstetrics of the University Clinical Hospital and diagnosed with PCOS using Rotte...
Article
Background : During the initial COVID-19 outbreak, organizational changes were required to ensure adequate staffing in healthcare facilities. The extent to which organizational changes impacted the mental wellbeing of healthcare workers (HCWs) remains unexplored. Here we analyzed the association between three work-related stressors (reported access...
Article
Full-text available
The prevalence of asthma is considerably high among women of childbearing age. Most asthmatic women also often have other atopic disorders. Therefore, the differentiation between patients with atopic diseases without asthma and asthmatics with coexisting diseases is essential to avoid underdiagnosis of asthma and to design strategies to reduce symp...
Chapter
Background: We have previously reported that semen quality has drastically declined in Southern Spain during the last decade. Low serum vitamin D has been associated with low sperm motility in some epidemiological studies. In Spain, despite a high average sun exposure, population studies have shown that vitamin D serum levels are suboptimal and tha...
Article
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This study evaluates whether women with PCOS have a different body composition than non-PCOS women (controls), estimated by anthropometric methods, and whether body composition and PCOS condition could be predictors of insulin resistance (IR) and lipid profile (LP) in an independent manner. A case-control study was conducted in which women (126) we...
Article
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Paracetamol is the one of the most commonly used medications during pregnancy. However, its potential antiandrogenic effect has been suggested. The objective of this study was to evaluate associations between maternal paracetamol use during pregnancy and anogenital distance (AGD) in male newborns from a Spanish birth cohort. The study included two...
Article
Full-text available
Endometriosis is a disabling disease that may significantly compromise a woman’s social relationships, sexuality, and mental health. Considering the impact of endometriomas and deep infiltrating endometriosis (DIE) on quality of life and the limited number of papers on this topic, the objective of this study was to assess health-related quality of...
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Aim The objective of this study was to evaluate associations between maternal concentrations of 25‐hydroxyvitamin D (25(OHD)) and birth outcomes: mode of delivery and episiotomy rate. Design and Methods One hundred and seventeen pregnant women were enrolled in an observational, longitudinal, prospective cohort study. Multivariable linear regressio...
Article
Background Bisphenol A (BPA) is one of the most common endocrine disruptor compounds in our environment, promoting a xenoestrogenic state. Numerous studies have shown a relationship between exposure to BPA and male infertility problems. Spermatic DNA integrity is a critical factor for the correct transmission of paternal genetic material to the emb...
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Full-text available
Objectives To evaluate four sample treatments in a safe and simple procedure for SARS-CoV-2 detection in saliva. Methods Four sample treatments in three-step procedure for the detection of SARS-CoV-2 in saliva, consisting in 1) heating at 95 °C during 5 minutes for sample inactivation, 2) sample treatment, and 3) analysis by RT-LAMP were evaluated...
Article
Objectives: The aim of the present study was to validate a commercially available automated assay for the measurement of total adenosine deaminase (tADA) and its isoenzymes (ADA1 and ADA2) in saliva in a fast and accurate way, and evaluate the possible changes of these analytes in individuals with SARS-CoV-2 infection. Methods: The validation, i...
Article
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To describe whether polycystic ovary syndrome (PCOS) phenotypes vary in their body composition and skinfold (SKF) thicknesses and if they differ from women without PCOS, a preiminar case-control study was performed. A total of 117 cases were diagnosed using the Rotterdam criteria. Gynecological examinations and transvaginal ultrasound were performe...
Article
Full-text available
Polycystic ovary syndrome (PCOS) is a chronic endocrinopathy characterized by hyperandrogenism and anovulation that may pervade psychological dimensions such as dispositional optimism. Considering how PCOS influences mental health and the lack of studies on this matter, this research was aimed at assessing optimism and associated factors in PCOS. A...
Article
Full-text available
Polycystic ovary syndrome (PCOS) is a complex hormonal disorder which impairs ovarian function. The adherence to healthy dietary patterns and physical exercise are the first line of recommended treatment for PCOS patients, but it is yet unclear what type of diet is more adequate. In this case-control study, we explored associations between adherenc...
Preprint
Full-text available
Polycystic ovary syndrome (PCOS) is a complex hormonal disorder which impair ovarian function. The adherence to healthy dietary patterns and physical exercise are the first line of recommended treatment for PCOS patients, but it is no clear what type of diet is more adequate. In this case-control study, we explore the association between the adhere...
Conference Paper
Background There has been a decrease in male fertility in recent years. During the same period, there were important dietary changes, including an increase in sugar-sweetened beverage intake (SSB). The relation between SSB and male reproduction functions in humans are barely described in the literature. Methods Cross-sectional study with 209 parti...
Article
The objective of this study was to assess the accuracy of the combination of anogenital distance (AGD) and anti-Müllerian hormone (AMH) in the diagnosis of polycystic ovary syndrome (PCOS). The study included women diagnosed with PCOS and a control group who attended the Clinical University Hospital ‘Virgen de la Arrixaca’ in Murcia (Spain). Serum...
Article
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Background: Polycystic ovary syndrome (PCOS) is a chronic condition with symptoms affecting many women at reproductive age and evaluating their health-related quality of Life (HRQoL) is an important issue. Moreover, differences in the HRQoL between women with different PCOS phenotypes have never been analyzed. Therefore, the aim of our study was t...
Article
RESEARCH QUESTION: Does the length of the anogenital distance (AGD) –an anthropometric biomarker of fetal androgen exposure- change across pregnancy? It has been suggested that AGD remains stable during adulthood and that there are no changes across the menstrual cycle. However, no studies have been carried out during pregnancy, where women are exp...
Article
Full-text available
Resumen Objetivo Evaluar la asociación entre el cociente de los dedos segundo y cuarto (2D:4D), como un biomarcador de la exposición prenatal a andrógenos, y la presencia de cáncer de próstata (CaP). Métodos Estudio de casos y controles con 260 hombres que consultaron en el Servicio de Urología del Hospital General Universitario Reina Sofía (Murcia...
Article
Full-text available
Background Current evidence is insufficient to determine the contribution of stent grafts as treatment in partially thrombosed aneurysms or residual wall-adherent thrombi in arteriovenous fistulae (AVFs) for haemodialysis. The overall purpose of this study was to analyse patency rates of post-interventional covered stent deployment in those cases....
Preprint
Full-text available
Background Previous studies evaluating health-related quality of Life (HRQoL) in women with polycystic ovary syndrome (PCOS) present some methodological limitations. Moreover, differences in the HRQoL between different PCOS phenotypes have never been analyzed. Therefore, the aim of our study was to compare the HRQoL between women with PCOS -and its...
Article
Introduction: Endometriosis is a chronic painful condition characterized by high prognostic uncertainty, as well as the threat of infertility and emotional symptoms that may affect many aspects of women, including psychological characteristics like dispositional optimism. Considering the impact of endometriosis on psychological health and the pauci...
Preprint
Full-text available
Background: Polycystic ovary syndrome (PCOS) is a chronic condition with symptoms affecting many women at reproductive age and evaluating their health-related quality of Life (HRQoL) is an important issue. Moreover, differences in the HRQoL between women with different PCOS phenotypes have never been analyzed. Therefore, the aim of our study was to...
Preprint
Full-text available
Background: Polycystic ovary syndrome (PCOS) is a chronic condition with symptoms affecting many women at reproductive age and evaluating their health-related quality of Life (HRQoL) is an important issue. Moreover, differences in the HRQoL between women with different PCOS phenotypes have never been analyzed. Therefore, the aim of our study was to...
Article
Background: Relatively low sperm count was reported among young Spanish men in 2013. Several potential culprits have been suggested as explanations for reported trends in sperm counts in Western men, including lifestyles. Although controversial, some studies suggest that semen parameters, such as low sperm motility or abnormal morphology, may be a...
Article
Full-text available
Study question: Is adherence to an a priori defined diet quality indices [Alternate Healthy Index 2010 (AHEI-2010), relative Mediterranean diet score (rMED) or dietary approaches to stop hypertension (DASH)] associated with semen quality and reproductive hormone levels in young men? Summary answer: Greater adherence to the DASH diet is related t...
Article
Research question: Polycystic ovary syndrome (PCOS) women have increased cardiovascular risks, although it is unclear whether the haemostatic system and coagulation contribute to that increased risk. Design: Women attending the Gynecology Unit of the 'Virgen de la Arrixaca' University Hospital (Murcia, Spain) for routine gynaecological examinati...
Article
Objective: To evaluate the associationbetween anogenital distance (AGD), as a biomarker ofprenatal androgen milieu, and risk of prostate cancer(PCa). Methods: A case-control study was conducted on260 men attending a university hospital where theyunderwent physical and andrological examination andcompleted a brief questionnaire. PCa patients were...
Article
Full-text available
The aim of this study was to assess the associations of intake of different types of meat with semen parameters and reproductive hormones in healthy young men. This cross-sectional study included 206 men, 18–23 years, from Southern Spain. All men completed a validated FFQ, underwent a physical examination, and provided blood and semen samples. Mult...
Article
Objective: To assess the predictive ability of a combination of anogenital distance (AGD) and anti-Müllerian hormone (AMH) to diagnosis the presence of endometriosis without surgery. Methods: The present study included women diagnosed with endometriosis and a control group who attended the "Virgen de la Arrixaca" University Hospital, Murcia, Spa...
Article
Anogenital distance (AGD) is a sexually dimorphic attribute, twice longer in males than in females, and a marker of intrauterine hormonal environment. Interest in AGD measurements is increasing due to mounting evidence on their potential clinical implications. A parallel set of perineal measurements, the Pelvic Organ Prolapse Quantification System...
Article
Full-text available
Background: Alcohol-related health and social problems amongst underage are increasing globally. Most studies have focused on the quality of parental relationships. However, less evidence is available to support the association between alcohol consumption and the birth order or the interaction between siblings. The objective of this study was to an...
Article
Objective: Anogenital distance (AGD), the distance from the centre of the anus to the genitals, is a sexually dimorphic phenotype in mammals. Several experimental studies have demonstrated that AGD is a biomarker of prenatal androgen exposure during the masculinisation period of development. The objective of this study was to assess the relationsh...
Article
OBJECTIVE: Anogenital distance (AGD), the distance from the centre of the anus to the genitals, is a sexually dimorphic phenotype in mammals. Several experimental studies have demonstrated that AGD is a biomarker of prenatal androgen exposure during the masculinisation period of development. The objective of this study was to assess the relationshi...
Article
Purpose: The purpose of this study was to compare patency rates and risk of obstruction of catheter exchange (CE) with that of CE with fibrin sheath angioplasty (CE+FSA) in dysfunctional tunneled central hemodialysis venous catheter (CHVC). Materials and methods: A total of 107 consecutive patients with dysfunctional CHVC were retrospectively in...
Article
Research question: Is anogenital distance (AGD) a useful clinical tool for predicting polycystic ovarian syndrome (PCOS) and its main National Institutes of Health (NIH) phenotypes? Design: Case-control study conducted between September 2014 and May 2016 at the Department of Obstetrics and Gynecology of the University Clinical Hospital 'Virgen d...
Article
Aims Anogenital distance (AGD) has been proposed as a marker of the prenatal hormonal milieu and potential environmental insults. The measures of the Pelvic Organ Prolapse‐Questionnaire (POP‐Q) system is being widely used in the evaluation of the perineum in women with POP pathologies. Genital hiatus (GH) and perineal body (PB) lengths have been re...
Article
Full-text available
Objetivo La ratio digital del segundo y cuarto dedo de la mano (2D:4D) es un marcador de la exposición a andrógenos prenatal que presenta un dimorfismo sexual en mamíferos, siendo menor en hombres que en mujeres. El objetivo de nuestro estudio fue analizar la asociación entre la ratio 2D:4D (como marcador indirecto del ambiente hormonal intrauterin...
Article
Full-text available
This study tries to describe the manifestations of behavioral and emotional psychopatology in adolescents who are asisted for the first time in an outpatient mental health center. For this, externalizing and internalizing patterns of behavior are measured though YSR (Youth Self Report) and Parent Child Relationship Inventory (PCRI) and sex differen...
Article
Resumen Objetivo El objetivo de este trabajo fue analizar las asociaciones entre el índice inflamatorio de la dieta (IID) y los parámetros reproductivos masculinos. Material y método Estudio transversal realizado en 209 jóvenes universitarios sanos (18-23 años) de la Región de Murcia entre octubre 2010 y noviembre 2011. Los análisis seminales (co...
Article
Resumen Introducción y objetivo La distancia entre los genitales y el ano (distancia anogenital [AGD]) es un reflejo de la concentración de andrógenos durante el desarrollo prenatal en mamíferos. En la actualidad solo existe un estudio que indique la relación entre AGD y riesgo de presentar cáncer de próstata (CaP). El objetivo de este estudio fue...
Article
Resumen Objetivo El objetivo de este trabajo fue analizar las asociaciones entre la ingesta dietaria de oligoelementos y la calidad seminal y los niveles de hormonas reproductivas en varones jóvenes. Material y método Se trata de un estudio transversal realizado en jóvenes universitarios sanos (n = 209) de la Región de Murcia entre 2010 y 2011. L...
Article
Background: Benzophenone (BP)-type ultraviolet (UV) light filters are chemicals frequently added to personal care products, insect repellents, sunscreens, and beverage and food packaging to diminish the harmful effects of UV sunlight on human skin or foodstuffs. BP-type UV filters have shown negative effects on male reproduction function in in vit...
Article
Full-text available
The purpose of this study was to analyze whether the anogenital distance (AGD) was associated with variability in semen parameters. Semen parameters analyzed following the WHO guidelines and sperm DNA fragmentation were evaluated in 160 semen samples obtained over a period of a year from 16 healthy male volunteers. Two types of AGD measurements fro...
Article
Parabens are a group of alkyl esters of p-hydroxybenzoic acid that are commonly added to personal care products, cosmetics, pharmaceuticals and beverage and food processing as antimicrobial preservatives. Parabens have been reported to show estrogenic effects and affect male reproduction function in animal models, but human epidemiologic studies ar...
Article
Bisphenol A (BPA) is a pervasive environmental toxicant with known reproductive effects on sperm parameters and hormone levels. Several observational studies have investigated the associations between BPA exposure and male reproductive function, but findings are inconsistent. The objective of this study was to assess the associations between urinar...
Article
Study question: Is polycystic ovary syndrome (PCOS) associated with anogenital distance (AGD), a biomarker of fetal androgen exposure, in adult Mediterranean women? Summary answer: Longer AGD is associated with PCOS in adult Mediterranean women. What is known already: AGD is a biomarker of prenatal androgen milieu. Human observational studies...
Article
An association between anogenital distance (AGD) and endometriosis has been reported, suggesting that AGD may be a useful clinical tool in endometriosis. The predictive ability of AGD of women in discriminating presence and type of endometriosis was examined. A case-control study was conducted at the University Hospital ‘Virgen de la Arrixaca’, Mur...
Article
Full-text available
Purpose: The overall purpose of this study is to compare the accuracy of physical examination (PE) versus ultrasonography (US) in people with arteriovenous fistula (AVF). Methods: This is a cross-sectional study with a total of 99 patients attended by the vascular radiology unit for AVF evaluation during January - March 2015. PE and ultrasonogra...
Article
Background: Anogenital distance (AGD), the distance from the centre of the anus to the genitals, is a sexually dimorphic phenotype in mammals. Experimental studies have shown that AGD is a biomarker of prenatal androgen exposure during the masculinisation period of development. The aim of this study is to assess the relationship between anogenital...
Article
Full-text available
Emerging evidence suggests that dietary fats may influence testicular function. However, most of the published literature on this field has used semen quality parameters as the only proxy for testicular function. We examined the association of fat intake with circulating reproductive hormone levels and testicular volume among healthy young Spanish...