Alberto Pérez-Cervera

• Assistant Professor at Polytechnic University of Catalonia

The phase-amplitude framework extends the classical phase reduction method by incorporating amplitude coordinates (or isostables) to describe transient dynamics transverse to the limit cycle in a simplified form. While the full set of amplitude coordinates provides an exact description of oscillatory dynamics, it maintains the system's original dim...

Phase reduction is an important tool for studying coupled and driven oscillators. The question of how to generalize phase reduction to stochastic oscillators remains actively debated. In this work, we propose a method to derive a self-contained stochastic phase equation of the form dϕ = a(ϕ) dt + sqrt(2D(ϕ)) dW (t) that is valid not only for noise-...

Many systems in physics, chemistry, and biology exhibit oscillations with a pronounced random component. Such stochastic oscillations can emerge via different mechanisms, for example, linear dynamics of a stable focus with fluctuations, limit-cycle systems perturbed by noise, or excitable systems in which random inputs lead to a train of pulses. De...

Many systems in physics, chemistry and biology exhibit oscillations with a pronounced random component. Such stochastic oscillations can emerge via different mechanisms, for example linear dynamics of a stable focus with fluctuations, limit-cycle systems perturbed by noise, or excitable systems in which random inputs lead to a train of pulses. Desp...

Brain rhythms emerge from synchronization among interconnected spiking neurons. Key properties of such rhythms can be gleaned from the phase-resetting curve (PRC). Inferring the PRC and developing a systematic phase reduction theory for large-scale brain rhythms remains an outstanding challenge. Here we present a theoretical framework and methodolo...

Seminal work by A. Winfree and J. Guckenheimer showed that a deterministic phase variable can be defined either in terms of Poincaré sections or in terms of the asymptotic (long-time) behaviour of trajectories approaching a stable limit cycle. However, this equivalence between the deterministic notions of phase is broken in the presence of noise. D...

Thomas and Lindner [P. J. Thomas and B. Lindner, Phys. Rev. Lett. 113, 254101 (2014).], defined an asymptotic phase for stochastic oscillators as the angle in the complex plane made by the eigenfunction, having a complex eigenvalue with a least negative real part, of the backward Kolmogorov (or stochastic Koopman) operator. We complete the phase-am...

Thomas and Lindner (2014, Phys.Rev.Lett.) defined an asymptotic phase for stochastic oscillators as the angle in the complex plane made by the eigenfunction, having complex eigenvalue with least negative real part, of the backward Kolmogorov (or stochastic Koopman) operator. We complete the phase-amplitude description of noisy oscillators by defini...

The mechanisms underlying the emergence of seizures are one of the most important unresolved issues in epilepsy research. In this paper, we study how perturbations, exogenous or endogenous, may promote or delay seizure emergence. To this aim, due to the increasingly adopted view of epileptic dynamics in terms of slow-fast systems, we perform a theo...

Explaining the behaviour of ecosystems is one of the key challenges for the biological sciences. Since 2000, new-mechanicism has been the main model to account for the nature of scientific explanation in biology. The universality of the new-mechanist view in biology has been however put into question due to the existence of explanations that accoun...

Brain rhythms emerge as a result of synchronization among interconnected spiking neurons. Key properties of such rhythms can be gleaned from the phase-resetting curve (PRC). Inferring the macroscopic PRC and developing a systematic phase reduction theory for emerging rhythms remains an outstanding theoretical challenge. Here we present a practical...

The mechanism underlying the emergence of seizures is one of the most important unresolved issues in epilepsy research. In this paper, we study how perturbations, exogenous of endogenous, may promote or delay seizure emergence. To this aim, due to the increasingly adopted view of epileptic dynamics in terms of slow-fast systems, we perform a theore...

In this paper, we use the parameterization method to provide a complete description of the dynamics of an n-dimensional oscillator beyond the classical phase reduction. The parameterization method allows us, via efficient algorithms, to obtain a parameterization of the attracting invariant manifold of the limit cycle in terms of the phase-amplitude...

In this paper we use the parameterization method to provide a complete description of the dynamics of an $n$-dimensional oscillator beyond the classical phase reduction. The parameterization method allows, via efficient algorithms, to obtain a parameterization of the attracting invariant manifold of the limit cycle in terms of the phase-amplitude v...

The phase response curve (PRC) is a tool used in neuroscience that measures the phase shift experienced by an oscillator due to a perturbation applied at different phases of the limit cycle. In this paper, we present a new approach to PRCs based on the parameterization method. The underlying idea relies on the construction of a periodic system whos...

The theory of communication through coherence (CTC) proposes that brain oscillations reflect changes in the excitability of neurons, and therefore the successful communication between two oscillating neural populations depends not only on the strength of the signal emitted but also on the relative phases between them. More precisely, effective comm...

We study the dynamics arising when two identical oscillators are coupled near a Hopf bifurcation where we assume a parameter ϵ uncouples the system at ϵ=0. Using a normal form for N=2 identical systems undergoing Hopf bifurcation, we explore the dynamical properties. Matching the normal form coefficients to a coupled Wilson–Cowan oscillator network...

The theory of communication through coherence (CTC) proposes that brain oscillations reflect changes in the excitability of neurons, and therefore the successful communication between two oscillating neural populations depends not only on the strength of the signal emitted but also on the relative phases between them. More precisely, effective comm...

Explaining the behaviour of ecosystems is one of the key challenges for the biological sciences. Since 2000, new-mechanicism has been the main model to account for the nature of scientific explanation in biology. The universality of the new-mechanist view in biology has been however put into question due to the existence of explanations that accoun...

We study the dynamics arising when two identical oscillators are coupled near a Hopf bifurcation where we assume a parameter $\epsilon$ uncouples the system at $\epsilon=0$. Using a normal form for $N=2$ identical systems undergoing Hopf bifurcation, we explore the dynamical properties. Matching the normal form coefficients to a coupled Wilson-Cowa...

Explaining the behaviour of ecosystems is one of the key challenges for the biological sciences. Since 2000, new-mechanicism has been the main model to account for the nature of scientific explanation in biology. The universality of the new-mechanist view in biology has been however put into question due to the existence of explanations that accoun...

The Phase Response Curve (PRC) is a tool used in neuroscience that measures the phase shift experienced by an oscillator due to a perturbation applied at different phases of the limit cycle. In this paper we present a new approach to PRCs based on the parameterization method. The underlying idea relies on the construction of a periodic system whose...

Background oscillations, reflecting the excitability of neurons, are ubiquitous in the brain. Some studies have conjectured that when spikes sent by one population reach the other population in the peaks of excitability, then information transmission between two oscillating neuronal groups is more effective. In this context, phase locking relations...