Alberto Mavilio

Azienda Sanitaria Locale Brindisi | ASL Brindisi · Electrophysiology of Vision

Objective: To evaluate variability of steady-state pattern electroretinogram (SS-PERG) signal in normal, suspected, and glaucomatous eyes. Methods: Twenty-one subjects with suspected glaucoma due to disc abnormalities (GS), 37 patients with early glaucoma (EG), and 24 normal control (NC) were tested with spectral-domain optical coherence tomogra...

RE-PERG can detect variations in the metabolic status of the RGCs in glaucomatous patients after oral intake of a fixed combination of C+H in addition to topical treatment. RE-PERG can be a valid tool in neuroenhancement studies, representing a biological marker of neuronal performance

Purpose: RE-PERG is altered in presence of primary neuronal degeneration of retinal ganglion cells, both in glaucoma and other diseases. A previous study showed that in a model of retrograde degeneration (vascular dementia) RE-PERG was normal. In this study, we enrolled patients with pituitary adenoma (PA) to evaluate RE-PERG findings in another m...

Purpose Spectral-domain optical coherence tomography (SD-OCT) was used to evaluate, in patients with multiple sclerosis without a history of optic neuritis (MSNON), the proportion of the different macular ganglion cell-inner plexiform layer complex (mGCIP) defect patterns. The results were compared with those of healthy controls (HCs). Methods In...

Purpose To evaluate the potential beneficial and synergistic effects of oral intake of a fixed combination of citicoline 500 mg plus homotaurine 50 mg (CIT/HOMO) on retinal ganglion cell (RGC) function in subjects with glaucoma using pattern electroretinogram (PERG) and to investigate the effects on visual field and quality of life. Methods Consec...

Purpose: To investigate the ocular manifestations in 91 Waldenström’s macroglobulinemia (WM) patients.Methods: Retrospective, cross-sectional, observational analysis.Results: Ocular impairments, detected in 19 patients, included flame-shaped hemorrhages, venous sausaging, papilledema, macular detachments, or central retinal vein occlusion in 16 pat...

PurposeTo describe the ocular manifestations in a cohort of patients with systemic sarcoidosis (SS). Recent advances in the pathophysiology, diagnosis, and therapy of SS are also discussed.Methods Data from 115 Italian patients diagnosed between 2005 and 2016 were retrospectively reviewed. All but the first 17 patients underwent a comprehensive oph...

18 eye doctor | luglio-agosto | 4/2020 ISCEV, la Società Internazionale per l'Elettrofisiologia della Visione, fu fondata nel 1958 allo scopo di diffondere le linee guida per una corretta esecuzione degli esami elettrofunzionali e per dettare gli standard di calibrazione poiché sin da subito fu avvertita l'esigenza di confrontare i risultati tra la...

Purpose To evaluate the ability of re-test pattern electroretinogram (RE-PERG), a non-invasive and fast steady-state PERG, to detect inner retinal bioelectric function anomalies in patients with early-onset Alzheimer’s disease (AD). Methods The study population consisted of 17 patients with AD-related mild cognitive impairment (MCI), 16 patients w...

Purpose To evaluate reliability of steady-state pattern electroretinogram (ssPERG) phase variability in re-test (procedure called RE-PERG) in the presence of myopia, which is known to affect ssPERG amplitude, in glaucomatous patients (GP), normal controls (NC), and myopic patients (MY). Methods The procedure was performed on 50 GP, 35 NC, and 19 M...

Purpose A significant variability of the second harmonic (2ndH) phase of steady-state pattern electroretinogram (SS-PERG) in intrasession retest has been recently described in glaucoma patients (GP), which has not been found in healthy subjects. To evaluate the reliability of phase variability in retest (a procedure called RE-PERG or REPERG) in the...