Alana Olegovna Agnaeva- PhD Student at Research Institute of Obstetrics and Gynecology named after D.O. Ott
Alana Olegovna Agnaeva
- PhD Student at Research Institute of Obstetrics and Gynecology named after D.O. Ott
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9
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Introduction
Current institution
Publications
Publications (9)
BACKGROUND:In obstetrics and reproductive medicine, the use of intravenous immunoglobulin remains controversial. There are no clearly developed indications for immunoglobulins therapy. The search for immunological criteria for prescribing this therapy is an urgent task AIM:The aim of this study was to evaluate the effectiveness of the use of intrav...
BACKGROUND: Currently, more than a hundred immunological biomarkers are known that are important for fertilization, implantation and placentation. AIM: The aim of this study was to assess the immunological profile for the main allo- and autoantibodies in women with reproductive loss and infertility in the North-West region of the Russian Federation...
The aim of this research was to assess the proliferative activity of Natural Killer Cells (NK cells) from Peripheral Blood Mononuclear Cells (PBMCs) in the presence of trophoblast cells in women with a history of recurrent miscarriages. We examined the peripheral blood of women with recurrent miscarriage in the proliferative (n = 12) or secretory (...
The trial objective was to determine the peripheral blood NK cells cytotoxic activity effect on trophoblast cells at recurrent pregnancy loss (RPL). The investigation involved non-pregnant women with PRL in proliferating and secretory menstrual cycle phases (PMCPh and SMCPh, respectively); women of 6–7 weeks pregnancy with RPL in past medical histo...
We evaluated cytotoxic activity of peripheral blood NK cells towards trophoblast cells. NK cells either isolated or in the composition of mononuclear cell fraction, caused death of trophoblast cells. In women with physiological pregnancy, the cytotoxic effect of NK cells present in mononuclear cell fraction preincubated with IL-2 was lower than in...
Изобретение относится к области медицины, а именно к репродуктивной медицине, и может быть использовано для оценки риска невынашивания беременности. Для этого определяют цитотоксическую активность NK-клеток периферической крови в секреторной фазе менструального цикла в отношении клеток трофобласта линии Jeg-3, и, если значение цитотоксической актив...
Изобретение относится к области медицины, и может быть использовано для оценки цитотоксической активности NK-клеток фракции мононуклеаров периферической крови. Для этого мононуклеары периферической крови, содержащие NK-клетки, инкубируют в культуральной среде DMEM в течение 4 часов, затем в течение 4 часов – с клетками трофобласта линии Jeg-3, част...
Reproductive losses are quite frequent in the modern world. They include: infertility, infertility of unknown etiology, multiple losses when IVF, recurrent implantation failure, miscarriage, recurrent miscarriage, both in the natural cycle and after ART management. It is important to note that the classification of some of these categories are not...
Despite achievements in area of reproductive medicine, recurrent pregnancy loss (RPL) remains the most frequent complication of pregnancy. While the majority of spontaneous abortions (50-75 %) are sporadic and don’t repeat, 2-5 % of couples face problem of repeated pregnancy losses. There is a set of various reasons of such situation. The immunolog...
