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Introduction
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- Medical Doctor
Publications
Publications (93)
Objectives
The heterogeneity of tinnitus in terms of etiology, presentation and sometimes severe impact on quality of life hinders treatment and clinical research. The European School for Interdisciplinary Tinnitus Research Screening Questionnaire (ESIT-SQ) collects standardized tinnitus characteristics for patient subtyping. A validated French tra...
Background
This study was aimed at identifying key topics in online discussions about tinnitus by examining a large data set extracted from Reddit social media using a natural language processing technique.
Method
A corpus of 113,215 posts about tinnitus was extracted from Reddit's application programming interface. After cleaning the data for dup...
As for hypertension, chronic pain, epilepsy and other disorders with particular symptoms, a commonly accepted and unambiguous definition provides a common ground for researchers and clinicians to study and treat the problem. The WHO's ICD11 definition only mentions tinnitus as a nonspecific symptom of a hearing disorder, but not as a clinical entit...
As for hypertension, chronic pain, epilepsy and other disorders with particular symptoms, a commonly accepted and unambiguous definition provides a common ground for researchers and clinicians to study and treat the problem. The WHO's ICD11 definition only mentions tinnitus as a nonspecific symptom of a hearing disorder, but not as a clinical entit...
Background: Several clinical studies have shown that neurofeedback (NFB) has the potential to significantly improve the quality of life of patients complaining of chronic subjective tinnitus. Yet the clinical applicability of such a therapeutic approach in the everyday practice has not been tested so far.
Objective: This study aims at investigating...
Résumé
Objectifs
Évaluer l’efficacité d’un protocole de sophrologie adapté à la prise en charge des acouphènes subjectifs invalidants en déterminant, sans comparaison à un groupe contrôle, si cette technique permet d’atténuer le handicap associé à la perception acouphénique.
Matériels et méthodes
Une population de 140 patients consécutifs (18–83...
Riassunto
Gli acufeni soggettivi sono delle percezioni uditive che non rispondono a una stimolazione sonora registrabile. Sono generalmente sintomatici di una lesione attiva o sequenziale del sistema uditivo periferico. Tuttavia, i meccanismi fisiopatologici multipli e intricati che spiegano sia la loro emergenza che la loro connotazione spiacevole...
Resumen
Los acúfenos subjetivos son percepciones auditivas que no responden a una estimulación sonora registrable. Suelen ser sintomáticos de una lesión activa o de una secuela del sistema auditivo periférico. Sin embargo, lo más probable es que en los mecanismos fisiopatológicos múltiples e imbricados que explican tanto su aparición como su connot...
Objectives
To assess (without comparison versus controls) the efficacy of a sophrology protocol adapted to disabling subjective tinnitus, in diminishing the handicap induced by perception of tinnitus.
Materials and methods
One hundred and forty consecutive patients, aged 18–83 years, underwent a protocol comprising 6–8 sessions of sophrology over...
Introduction:
Subjective tinnitus (ST) and hyperacusis (HA) are common auditory symptoms that may become incapacitating in a subgroup of patients who thereby seek medical advice. Both conditions can result from many different mechanisms, and as a consequence, patients may report a vast repertoire of associated symptoms and comorbidities that can r...
A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently rev...
La hiperacusia es un síntoma otológico relativamente frecuente, asociado a menudo a un acúfeno subjetivo, que puede afectar a la evolución de numerosas patologías otorrinolaringológicas, neuropsicológicas o sistémicas. En los casos más graves, puede provocar una importante desocialización de los pacientes, que se ven obligados a aislarse en un ento...
L’iperacusia è un sintomo otologico relativamente frequente, spesso associato a un acufene soggettivo, che può costellare l’evoluzione di molte patologie oto-rino-laringoiatriche, neuropsicologiche o generali. Nei casi più gravi, può portare a una grave desocializzazione degli individui affetti, che sono costretti a isolarsi in un ambiente artifici...
Background:
The heterogeneity of tinnitus is substantial. Its numerous pathophysiological mechanisms and clinical manifestations have hampered fundamental and treatment research significantly. A decade ago, the Tinnitus Research Initiative introduced the Tinnitus Sample Case History Questionnaire, a case history instrument for standardised collect...
Good practice in clinical trials advocates common standards for assessing and reporting condition-specific complaints (“outcome domains”). For tinnitus, there is no common standard. The Core Outcome Measures in Tinnitus International Delphi (COMiT’ID) study created recommendations that are relevant to the most common intervention approaches for chr...
Subjective tinnitus is a chronic heterogeneous condition that is typically managed using intervention approaches based on sound devices, psychologically informed therapies, or pharmaceutical products. For clinical trials, there are currently no common standards for assessing or reporting intervention efficacy. This article reports on the first of t...
Supplemental Material4 - Supplemental material for The COMiT’ID Study: Developing Core Outcome Domains Sets for Clinical Trials of Sound-, Psychology-, and Pharmacology-Based Interventions for Chronic Subjective Tinnitus in Adults
Supplemental Material2 - Supplemental material for The COMiT’ID Study: Developing Core Outcome Domains Sets for Clinical Trials of Sound-, Psychology-, and Pharmacology-Based Interventions for Chronic Subjective Tinnitus in Adults
Supplemental Material3 - Supplemental material for The COMiT’ID Study: Developing Core Outcome Domains Sets for Clinical Trials of Sound-, Psychology-, and Pharmacology-Based Interventions for Chronic Subjective Tinnitus in Adults
Supplemental Material5 - Supplemental material for The COMiT’ID Study: Developing Core Outcome Domains Sets for Clinical Trials of Sound-, Psychology-, and Pharmacology-Based Interventions for Chronic Subjective Tinnitus in Adults
Supplemental Material1 - Supplemental material for The COMiT’ID Study: Developing Core Outcome Domains Sets for Clinical Trials of Sound-, Psychology-, and Pharmacology-Based Interventions for Chronic Subjective Tinnitus in Adults
Acoustic shocks and traumas sometimes result in a cluster of debilitating symptoms, including tinnitus, hyperacusis, ear fullness and tension, dizziness, and pain in and outside the ear. The mechanisms underlying this large variety of symptoms remain elusive. In this article, we elaborate on the hypothesis that the tensor tympani muscle (TTM), the...
Painting is essentially a visual form of arts. Apparently, audition and the hearing system seem to be of no avail in the aesthetic experience felt by painters during the creative process of artistic visual patterns, and by beholders while painting viewing. But philosophers and modern neuroscience have challenged this kind of unimodal and classical...
Tinnitus masking and residual inhibition (RI) are two well-known psychoacoustic measures of tinnitus. While it has long been suggested that they may provide diagnostic and prognostic information, these measures are still rarely performed in clinics, as they are too time consuming. Given this issue, the main goal of the present study was to validate...
Supplementary Tables -Supplemental material for A New Method for Assessing Masking and Residual Inhibition of Tinnitus
Résumé
L’acouphène subjectif est un symptôme présent dans de nombreuses pathologies ORL pour lequel il n’existe pas de thérapie curative. Il peut être mal toléré par certains patients qui développent des troubles attentionnels ou du sommeil voire des réactions anxio-dépressives majeures entraînant une altération importante de la qualité de vie. Dan...
Subjective tinnitus is a symptom in many ENT pathologies, for which there is no curative treatment. It may be poorly tolerated by some patients, who develop attention or sleep disorder or even major anxiety and depression, severely impairing quality of life. Pathophysiological models of the genesis and maintenance of tinnitus symptomatology highlig...
Background
The reporting of outcomes in clinical trials of subjective tinnitus indicates that many different tinnitus-related complaints are of interest to investigators, from perceptual attributes of the sound (e.g. loudness) to psychosocial impacts (e.g. quality of life). Even when considering one type of intervention strategy for subjective tinn...
This study reports the case of an acoustic shock injury (ASI), which did not result in a significant hearing loss, but was followed by manifold chronic symptoms both within (tinnitus, otalgia, tingling in the ear, tension in the ear, and red tympanum) and outside the ears (blocked nose, pain in the neck/temporal region). We suggest that these sympt...
The video shows the right eardrum when the feeling of tension in the ear is high and when it is low.
The video shows the right eardrum, when the tension in the ear is high, before, during, and after the mylohyoid muscle contraction.
The illusion of movement (stricto sensu definition of vertigo) is a sensory experience particularly badly experienced by the patient who undergoes a sudden alteration of his vestibular system, putting badly the representation of his body into space. This illusion of movement is sometimes sought in pictorial art and is likely to affect the spectator...
Neuroaesthetics is an emerging neuroscientific field aimed at explaining the cognitive processes and the neurobiological correlates actually involved in both artistic practices and aesthetic experiences. Indeed the essential role of vision has already been extensively studied, but recent data suggest that aesthetic interactions may rely upon a broa...
Background
There is no evidence-based guidance to facilitate design decisions for confirmatory trials or systematic reviews investigating treatment efficacy for adults with tinnitus. This systematic review therefore seeks to ascertain the current status of trial designs by identifying and evaluating the reporting of outcome domains and instruments...
There is no evidence-based guidance to facilitate design decisions for confirmatory trials or systematic reviews investigating treatment efficacy for adults with tinnitus. This systematic review therefore seeks to ascertain the current status of trial designs by identifying and evaluating the reporting of outcome domains and instruments in the trea...
Background:
Subjective tinnitus (ST) is a frequent audiologic condition that still requires effective treatment. This study aimed at evaluating two therapeutic approaches: Virtual Reality (VR) immersion in auditory and visual 3D environments and Cognitive Behaviour Therapy (CBT).
Methods:
this open, randomized and therapeutic equivalence trial u...
Subjective tinnitus (ST) is a frequent but poorly understood medical condition. Recent studies demonstrated abnormalities in several types of eye movements (smooth pursuit, optokinetic nystagmus, fixation, and vergence) in ST patients. The present study investigates horizontal and vertical saccades in patients with tinnitus lateralized predominantl...
Purpose:
This study was designed to investigate methods to help patients suffering from unilateral tinnitus synthesizing an auditory replica of their tinnitus.
Materials and methods:
Two semi-automatic methods (A and B) derived from the auditory threshold of the patient and a method (C) combining a pure tone and a narrow band-pass noise centred...
Chronic tinnitus is a common condition with a high burden of disease. While many different treatments are used in clinical practice, the evidence for the efficacy of these treatments is low and the variance of treatment response between individuals is high. This is most likely due to the great heterogeneity of tinnitus with respect to clinical feat...
cote interne IRCAM: ViaudDelmon12h
Repeated transcranial magnetic stimulation (rTMS) of auditory cortex has been proposed to treat refractory chronic tinnitus, but the involved mechanisms of action remain largely unknown. The purpose of this pilot study was to evaluate the impact of rTMS on auditory cortex activity in a series of tinnitus patients, using for the first time both func...
During the past decade, a large amount of work on transcranial magnetic stimulation (TMS) has been performed, including the development of new paradigms of stimulation, the integration of imaging data, and the coupling of TMS techniques with electroencephalography or neuroimaging. These accumulating data being difficult to synthesize, several Frenc...
Background: Many patients show modulation of tinnitus by gaze, jaw or neck movements, reflecting abnormal sensorimotor integration, and interaction between various inputs. Postural control is based on multi-sensory integration (visual, vestibular, somatosensory, and oculomotor) and indeed there is now evidence that posture can also be influenced by...
El acufeno es un síntoma audiológico muy frecuente que afecta a alrededor del 10% de la población general. Tanto si es audible por los allegados y/o registrable (acufeno objetivo) como si sólo lo percibe el paciente (acufeno subjetivo), corresponde a una percepción auditiva elemental de origen interno. El acufeno se suele tolerar bien, pero en algu...
Frequent oulomotricity problems with orthoptic testing were reported in patients with tinnitus. This study examines with objective recordings vergence eye movements in patients with somatic tinnitus patients with ability to modify their subjective tinnitus percept by various movements, such as jaw, neck, eye movements or skin pressure.
Vergence eye...
It is estimated that ~10% of the adult population in developed countries is affected by subjective tinnitus. Physiopathology
of subjective tinnitus remains incompletely explained. Nevertheless, subjective tinnitus is thought to result from hyperactivity
and neuroplastic reorganization of cortical and subcortical networks following acoustic deaffere...
El acufeno es una percepción auditiva «parásita» cuya naturaleza puede ser objetiva o subjetiva. En ocasiones se asocia a una hiperacusia. Cualquier acufeno obliga a realizar un proceso diagnóstico, destinado a determinar una posible etiología específica que obligue a un tratamiento adaptado a la enfermedad subyacente, pero también a eliminar una p...
L’acufene è una percezione uditiva «parassita» la cui natura può essere oggettiva o soggettiva. A volte si associa a un’iperacusia. Ogni acufene impone una valutazione diagnostica il cui scopo è quello di determinare un’eventuale eziologia specifica che richiede una terapia adeguata alla patologia sottostante, ma anche di escludere un’eventuale ezi...
Smooth pursuit (SP), optokinetic nystagmus (OKN) and fixation were investigated in five subjects with somatic tinnitus modulated by eye movements, jaw or neck.
Eye movements were recorded with the EyeLink II video system.
(1) Fixation was characterized by high frequency and amplitude of saccade intrusions; (2) SP had low gain particularly in the ve...
Tinnitus is a very frequent symptom affecting 10% of the general population. It corresponds to the perception of an internal noise that can severely impair the quality of life. Tinnitus management requires a multidisciplinary approach in which neuromodulation and neurosurgery tend to play major roles. Classification of tinnitus separates objective...
Tinnitus is a very frequent symptom affecting 10% of the general population. It corresponds to the perception of an internal noise that can severely impair the quality of life. Tinnitus management requires a multidisciplinary approach in which neuromodulation and neurosurgery tend to play major roles. Classification of tinnitus separates objective...
Spontaneous (SOEs) and evoked otoacoustic emissions (EOEs) were recorded in a group of preterm neonates (N = 134 ears) in order to study the basic properties of SOEs and EOEs as a function of gestational age. In the study, it was found that: 1. EOEs were recorded in 93% of the tested ears; 2. SOEs were recorded in 61% of the tested ears; 3. there w...
Tinnitus affects 10% of the population, its pathophysiology remains incompletely understood, and treatment is elusive. Functional imaging has demonstrated a relationship between the intensity of tinnitus and the degree of reorganization in the auditory cortex. Experimental studies have further shown that tinnitus is associated with synchronized hyp...
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method used to induce electrical current in the brain through impulses of strong magnetic fields applied externally. The technique can relieve tinnitus by modulating the excitability of neurons in the auditory cortex to decrease the hyperexcitability that is associated with gener...
There is widespread recognition that consistency between research centres in the ways that patients with tinnitus are assessed and outcomes following interventions are measured would facilitate more effective co-operation and more meaningful evaluations and comparisons of outcomes. At the first Tinnitus Research Initiative meeting held in Regensbur...
Introduction
Tinnitus is a common auditory symptom that interferes with activities of daily living and is often associated with anxiety and depression.
Method
This study included consecutive patients with chronic intense tinnitus for more than six months who were treated with Tinnitus Retraining Therapy (TRT), a cognitive-behavioral therapy, after...
Tinnitus is a common auditory symptom that interferes with activities of daily living and is often associated with anxiety and depression.
This study included consecutive patients with chronic intense tinnitus for more than six months who were treated with Tinnitus Retraining Therapy (TRT), a cognitive-behavioral therapy, after previous treatment f...
Subjective (non-recordable) tinnitus is the conscious perception of a phantom sound, and a very frequent, sometimes disabling, condition. Even if subjective tinnitus is often related to peripheral hearing loss, neurophysiological and functional imaging studies provide increasing evidence for an involvement both auditory and non-auditory central ner...
Tinnitus - the perception of sound in one or both ears or in the head when no external sound is present - can be disabling and is especially difficult to treat. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive technique for activating or inactivating specific areas of the cortex. The aim of this study was to assess the feasibili...
Objective
Tinnitus - the perception of sound in one or both ears or in the head when no external sound is present - can be disabling and is especially difficult to treat. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive technique for activating or inactivating specific areas of the cortex. The aim of this study was to assess the...
Tinnitus is a common otologic symptom but, despite important advances in the evaluation and management of such symptom, ENTs often fail to address tinnitus properly. Some tinnitus patients report that tinnitus interferes with activities of daily living, such as reading, social interactions, sleep, concentrating on complex tasks. Anxiety and depress...
Objectives
Tinnitus is a common otologic symptom but, despite important advances in the evaluation and management of such symptom, ENTs often fail to address tinnitus properly. Some tinnitus patients report that tinnitus interferes with activities of daily living, such as reading, social interactions, sleep, concentrating on complex tasks. Anxiety...
Unlabelled:
A FREQUENTLY MISUNDERSTOOD AFFECTION: Because of its high prevalence and the considerable alteration it often provokes in quality of life, tinnitus aurium is an important public health problem. Current treatment of tinnitus aurium is limited by the lack of knowledge of the physiopathological processes that generate it.
The various lea...
The influence of the frequency ratio f(2)/f(1) of two pure-tone stimuli on the distortion-product otoacoustic emissions (DPOAEs) at 2f(1)-f(2) was assessed in 14 hearing-impaired human ears exhibiting a narrow audiometric notch at 4 kHz, whereas 11 normally hearing ears served as controls. A fixed-f(2) paradigm was used, with f(2) values varying fr...
Second or more surgical procedures on parotid are usually difficult and may induce injury on the facial nerve. The authors report their experience about 42 patients. The choice between a total parotidectomy or a surgical excision of a tumor depends on the number of surgical procedure, the type of initial procedure and the histological type of the t...
Second or more surgical procedures on parotid are usually difficult and may induce injury on the facial nerve. The authors report their experience about 42 patients. The choice between a total parotidectomy or a surgical excision of a tumor depends of the number of surgical procedure, the type of initial procedure and the histological type of the t...
• The aim of this study was to measure distortion-product otoacoustic emissions (DPOEs) in a clinical setting. First, DPOE input-output functions were automatically realized to determine the ratio of the pure tones (primaries) f2 and f1 that would elicit the most significant DPOE input-output function. The DPOE input-output functions presented two...
This paper presents the first case of human genetic hearing loss due to predominant inner hair cell damage investigated by psychoacoustic audiometry, auditory brainstem responses (ABR), evoked acoustic emissions (EAEs), and distortion product otoacoustic emissions (DPOEs). The genetic transmission was an autosomal dominant inheritance. The audiogra...
We report one case of pseudotumoral salivary location of the Rosai-Dorfman syndrome, with a favorable outcome, occurring in a 32-year-old man from Guadeloupe. The clinical, biological and clinicopathological features of this syndrome, as well as the pathogenetic hypotheses, are summed up. In this case, no bacterial, fungal, parasitic or viral agent...
Acoustic distorsion products are sounds emitted by the cochlea, in relation with the outer hair cell properties and the micromechanical properties of the Organ of Corti, in response to an acoustic stimulation by two primairies F1 and F2. Acoustic distorsion product 2F1-F2 have been recorded in two populations: 10 normally-hearing subjects and 10 su...
