Akin Kirbas

Akin Kirbas
Bozok University · Department of Internal Medicine, Faculty of Veterinary Medicine

DVM PhD Associate Professor
Editorial Board Member BMC Veterinary Research

About

110
Publications
22,603
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492
Citations
Introduction
acute phase markers in neonatal animals, sepsis, septiceamia, SIRS, septic shock, acute phase reactans, veterinary internal medicine, large ainmal internal medicine, small animal internal medicine
Additional affiliations
August 2010 - present
Ataturk University
Position
  • Assist.Prof.Dr.
August 2010 - September 2016
Ataturk University
Position
  • Assist.Prof.Dr.
August 2010 - September 2016
Ataturk University
Position
  • Assist.Prof.Dr.

Publications

Publications (110)
Article
Full-text available
The objective of this study was to evaluate the usefulness of inflammatory markers as a diagnostic and prognostic approach in neonatal calves with septicemia. The study material consisted of 13 neonatal calves with septicemia (Septicaemic calves, SC) and ten healthy neonatal calves (Control calves, CC). Blood samples were collected for biochemical,...
Article
Full-text available
Pseudo-pericarditis-shaped theileriosis is a rare phenomenon that only a handful of reports have been introduced. This case report aims to describe pseudo-pericarditis due to tropical theileriosis diagnosed in a 7-year old crossbreed Simmental cow and 3-year old crossbreed Holstein cow with a loss of appetite, weakness, and weight loss. We have det...
Article
Full-text available
Sepsis is a serious condition with high mortality, which is frequently encountered in neonatal calves. Cardiovascular abnormalities due to sepsis frequently occur, therefore early diagnosis and treatment of sepsis is of great importance in the survival of calves. Cardiac troponin I (cTnI) is considered to be an excellent biomarker in the diagnosis...
Article
Full-text available
Iron and ferritin have been used in human medicine for years to reveal the presence of inflammation. However, studies evaluating these parameters, especially in respiratory system diseases, are quite rare in veterinary medicine. We aimed to test the usability of serum Fe and Fe-related parameters [total iron-binding capacity (TIBC), unsaturated iro...
Article
Full-text available
The purpose of this study was to determine the seroprevalence of Toxoplasmosis in equidae in the province of Muş of Turkey. The study material consisted of 210 equidae including 159 horses and 51 donkeys in Muş province. In serum samples, anti-Toxoplasma gondii antibodies and titers were detected using Sabin Feldman Dye Test (SFDT). Seropositivity...
Chapter
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MCF is a severe lymphoproliferative disease of cattle, buffalo, bison and deer, which is characterized by acute, catarrhal, mucopurulent, erosive-ulcerative and pseudomembranous lesions of the gastrointestinal tract, the oral cavity, and upper respiratory tract. AlHV-1 and OvHV-2 are the two most common etiologic agents. There are two epidemiologic...
Article
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Feline atopic syndrome is a condition in which cats can be exposed through breathing or contact, triggering hypersensitivity from environmental allergens. Atopic syndrome, which has characteristics similar to atopic dermatitis seen in dogs, is known to be associated with antibodies created against inflammatory, itchy, immunoglobulin E and environme...
Article
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Canine parvoviral enteritis is an enteropathogenic disease with high morbidity and mortality rates in susceptible dogs. The causative agent of the disease is 3 different substrains of parvoviral enteritis (CPV-2a, 2b and 2c). Infection is mostly caused by the ingestion of food contaminated with the faeces of infected animals by healthy and suscepti...
Chapter
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It is aimed to present current information about foreign body disease of cattle.
Article
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The purpose of this study was to evaluate of acute phase response and oxidative damage in sheep naturally infected with Streptococcus pluranimalium using haptoglobin (Hp), nitric oxide (NO), andmalondialdehyde (MDA) levels. The animal material of the study consisted of 60 sheep infected with S. pluranimalium (Infected group) aged between 4-6 years...
Article
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Alopecia X is a type of dermatosis seen in young adult dogs and characterized by cessation of hair cycle, high progesterone, low androgen, variable estrogen and mild increase in cortisol, without inflammation and itching. Alaskan Malamute, Chow-Cow, Keeshond, Norwegian Elkhound, Pomeranian and Samoyed breeds show more susceptibility and susceptibil...
Article
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Bovine papular stomatitis virus (BPSV) belongs to the genus Parapoxvirus of the family Poxviridae. Orf virus (ORFV), Pseudocowpox virus (PCPV), BPSV and Parapoxvirus of red deer in New Zealand (PVNZ) are also among the members of the genus Parapoxvirus. The BPSV affects ruminants of all age groups as well as frequently being transmitted to humans a...
Article
Full-text available
In this study, it was aimed to evaluate oxidative stress, serum biochemistry, trace elements, minerals, and testosterone and thyroid hormone levels in weaned calves with dermatophytosis. A total of 28 weaned Holstein calves were used in the study, including 6-8 months old, 14 with dermatophytosis (7 males, 7 females) and 14 healthy (7 males, 7 fema...
Article
Full-text available
Demodicosis case is characterized by the excessive increase of demodex mites on the hair follicles and skin surface as a result of the weakening of the skin immune system, especially in dogs exposed to immunosuppressive and secondary diseases. Although clinical diagnosis is not difficult, determination of the severity of infestation by effective di...
Conference Paper
Full-text available
Demodicosis case is characterized by the excessive increase of demodex mites on the hair follicles and skin surface as a result of the weakening of the skin immune system, especially in dogs exposed to immunosuppressive and secondary diseases. Although clinical diagnosis is not difficult, determination of the severity of infestation by effecti...
Article
Full-text available
The clinical use of drugs used in the treatment of diseases is limited due to the toxic side effects, and many studies have been conducted to benefit from herbal adjuvant therapies recently to eliminate these effects. In this study, the protective effect of zingerone against liver and kidney damage generated in rats through methotrexate. Histopatho...
Conference Paper
Full-text available
In this study, it was aimed to evaluate oxidative stress, serum biochemistry, trace elements, minerals, and testosterone and thyroid hormone levels in weaned calves with dermatophytosis. A total of 28 weaned Holstein calves were used in the study, including 6-8 months old, 14 with dermatophytosis (7 males, 7 females) and 14 healthy (7 males, 7 f...
Article
Full-text available
Downer cow syndrome (DCS) is a term used to describe cows who continue to lie in the sternal position for more than 24 hours despite treatment of hypocalcemia without showing any signs of systemic disease. There are a large variety of causes and their management is complex. Downer cow syndrome is associated with metabolic disorders such as hypocalc...
Conference Paper
Full-text available
In this study, the effects of zingerone (ZNG) was investigated in an experimental toxicity model induced by methotrexate (MTX), a commonly used chemotherapeutic agent and used in the treatment of various inflammatory diseases. For this purpose, 28 wistar albino rats were divided into four groups; Control (n: 7), ZNG (n: 7) ZNG 50 mg/kg p.o, MTX...
Article
Full-text available
Systemic inflammatory response syndrome (SIRS) is the set of events that the body gives hematologic and immunologic responses due to microbial contaminated and decontaminated reasons. It is sepsis that SIRS and infection co-exist. Infectious and non-infectious causes are important in etiology. Hyperemia and petechial bleeding foci, prolongation of...
Article
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The aim of this study was to evaluate plasma nitric oxide (NO) concentrations, erythrocyte arginase (ARG) activity, plasma fibrinogen (Fb) and serum iron (Fe) levels and some biochemical parameters in dairy cows with traumatic reticuloperitonitis (TRP). The animal material of the study consisted of 14 Swiss Brown cows diagnosed with TRP (TRP group)...
Conference Paper
Full-text available
Systemic inflammatory response syndrome (SIRS) is the set of events that body gives hematologic and immunologic responses due to microbial contaminated and decontaminated reasons. On the other hand, sepsis is the condition which SIRS and infection occur together. While viruses, bacterias, parasites, rickettsias, yeast and fungis take place as infec...
Conference Paper
Full-text available
Downer cows, defined as bright and alert cows that have been recumbent for more than one day, occur commonly in the dairy industry. Downer cow syndrome (DCS) has no universal definition although DCS is a term for cow their remains down in sternal recumbency following treatment for milk fever for more than 24h with no evidence of systemic illness Th...
Conference Paper
Full-text available
Aim: The aim of this study was to evaluate serum haptoglobin (Hp), nitric oxide (NO) and malondialdehyde (MDA) levels in naturally infected sheep with Streptococcus pluranimalium. Material and Method: The animal material of the study consisted of 60 sheep infected with Streptococcus pluranimalium (patient group) aged between 4-6 years and 15 health...
Conference Paper
Full-text available
Aim: This study aimed to evaluate serum iron (Fe), ferritin (Ferr), transferrin and unsaturated iron-binding capacity (UIBC) and haematological parameters in calves with bovine respiratory disease complex. Material and Method: The material of the study consisted of 15 calves, aged 1-3 months with bovine respiratory disease complex (Patient group, G...
Conference Paper
Full-text available
Aim: The aim of this study was to evaluate serum cardiac troponin-I (cTnI) concentration and cardiac enzyme activities (creatine kinase-MB [CK-MB], lactate dehydrogenase [LDH] and aspartate aminotransferase [AST] in neonatal calves with sepsis. Material and Method: The animal material of the study consisted of 15 neonatal calves with sepsis (Sepsis...
Conference Paper
Full-text available
Salicylic acid is a metabolite of acetylsalicylic acid (Aspirin) and is responsible for the anti-inflammatory effect of aspirin. Although the antiplatelet effect is specific to aspirin, salicylic acid and aspirin have similar properties. In this case report, it was aimed to report acute salicylic acid intoxication in a dog. The material of this cas...
Conference Paper
Full-text available
Aim: In this report, it is aimed to notify the neuromuscular involvement due to hypothyroidism in a Pekingese mix breed dog. Material and Method: The case consisted of a 7-year-old Pekingese mix breed dog who came to the clinic with a history of paralysis of the left side of his body. Biochemical and haematological examinations were performed. Brai...
Conference Paper
Full-text available
The purpose of this study is to determine the seroprevalence Toxoplasmosis inequidae inprovince of Mus, Turkey. The study material consisted of 210 equidae, including 159 horses and 51 donkeys in Mus province. Blood samples were taken from the vena jugularis of the animals, their sera were separated and kept at -80°C. In serum samples, Anti-Toxopla...
Conference Paper
The aim of this study was to define the oxidative-antioxidative capacity and lipid profile in goat with contagious agalactia. Twenty goat with contagious agalactia and 20 healthy goat were used in this study. Blood samples obtained from Jugular veins of animals were collected into plain tubes. Biochemical analysis included total oxidant capacity (T...
Conference Paper
Full-text available
Aim: In this report, it is aimed to notify the case of pseudo pericarditis due to tropical theileriosis detected in two cows. Materials and Method: A 7-year old crossbreed Simmental cow and 3-year old crossbreed Holstein cow, which were brought to the Animal Hospital of Ataturk University with the complaints of loss of appetite, weakness, and weig...
Conference Paper
Aim: In this study, it was aimed to evaluate plasma nitric oxide (NO) and erythrocyte arginase activities in dairy cows with traumatic reticuloperitonitis (TRP). Material and Method: The animal material of the study was composed of 14 Swiss Brown cows (TRP group) with TRP diagnosis between the ages of 4 and 8 brought to Fırat University Animal Hosp...
Conference Paper
Full-text available
___Background___ Bovine papular stomatitis virus (BPSV) is a parapoxvirus belongs to the family Poxviridae associated with papular and erosive lesions (painful reddish papules, ulcers, and scabby proliferative) on the muzzle, lips, and oral mucosa of cattle and also zoonotic disease. Although affects all age groups of a ruminant, the infection is f...
Article
Influenza virus infection is an important disease, which occurs in human beings and also in a variety of animals. The influenza A virus especially has a wide host adaptation. Because of the segmented genome, there is always the possibility of mutations and interspecies transmission of the influenza virus. The canine influenza virus was first diagno...
Conference Paper
Influenza virus infection is an important disease, which occurs in human beings and also in a variety of animals. The influenza A virus especially has a wide host adaptation. Because of the segmented genome, there is always the possibility of mutations and interspecies transmission of the influenza virus. The canine influenza virus was first diagno...
Conference Paper
In this case report, it was aimed to report the esophageal fistula detected in a 10 years old female Belgian Malinois race dog who were brought to the Atatürk University Veterinary Faculty Animal Hospital Small Animal Clinic for diagnosis and treatment. There was complaints of cough, regurgitation and fatigue after food and water intake in the pati...
Conference Paper
Introduction: The study aimed at evaluating oxidative stress using malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) markers in sheep naturally infected with Psoroptes ovis (Acari). Material and Methods: The study was performed on 40 sheep divided into two equal groups: a healthy g...
Article
It is known that inflammatory organ damages due to various agents, such as microorganisms including mycoplasmas, lead to oxidative stress. Nitric oxide (NO) functions as an antimicrobial agent, and arginase decreases proinflammatory cytokine release. There are very few studies on arginase activity, NO level and oxidative stress status in mycoplasma...
Article
It is recognized that inflammatory organ damages due to various agents, such as microorganisms, including mycoplasmas, lead to oxidative stress; nitric oxide (NO) functions as an antimicrobial agent; and arginase decreases proinflammatory cytokine release. There are very few studies on arginase activity, NO level and oxidative stress status in myco...
Article
Full-text available
In this case report, the pathological and clinical symptoms of coenurosis-which was diagnosed on a simmental bull at the age of two from the region of Erzurum, brought to the clinic with the complaint of neurological symptoms- are aimed to investigate. During anamnesis, we reached the information of the implementations like injections of florfenico...
Article
The objective of this study was to determine whether carprofen, flunixin meglumine and meloxicam could be used in emergency contraception. Forty-eight pregnant Sprague Dawley rats were used as material. Five groups were established as the treatment groups while one group served as a control. The numbers of animals in each group were equal (n = 8)....
Article
The study aimed at evaluating oxidative stress using malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) markers in sheep naturally infected with The study was performed on 40 sheep divided into two equal groups: a healthy group (group I) and a group naturally infected with The serum...
Article
The purpose of this study was to explore the protective effects of different doses of rutin with the antioxidant and anti-inflammatory properties on acute lung injury (ALI) induced by oleic acid (OA) in rats. Thirty-five Sprague-Dawley male rats were randomly separated into five groups comprising control, rutin 150 mg, OA, rutin 75 mg + OA and ruti...
Article
Full-text available
Hemochromatosis is characterized by excess iron accumulation in the body tissues, mainly in the liver. High amount of iron in food, genetic predisposition, components increasing iron absorption in food, and stress are the potent factors in the occurrence of the disease. The clinical diagnosis is quite difficult because clinical signs are not mostly...
Article
Full-text available
The objective of this study was to determine the effects of some antioxidant vitamins and trace elements on some metabolic and postpartum reproductive parameters in dairy cows during transition period. In the study, totally 20 clinically healthy Brown Swiss dairy cows (aged 4-5 years-old) under the same management and feeding conditions in peripart...
Article
Actinomycosis is commonly known as “lumpy jaw” that is a specific disease characterized with mandibular osteomyelitis in cattle. In our study, malondialdehyde, superoxide dismutase and some biochemical parameter levels in cattles with Actinomycosis were investigated. Thirty cattle were used in this study. 15 number of these were used as a control g...
Article
Sigirlarda gecis donemi dogum oncesindeki 3 hafta ile dogum sonrasi 3 haftayi kapsayan bir donem olarak tanimlanmaktadir. Bu calisma erkek ve disi yavru tasiyan esmer irki sigirlarin periparturient donemdeki bazi mineral, hormonal ve metabolik kan parametrelerinin karsilastirilmasi amaciyla yapilmistir. Calismada 20 gebe esmer irki inek (4-5 yaslar...
Article
Periparturient period in cows is defined the period that includes 3 weeks before and after from the parturition. This study aimed to investigate trace elements levels, metabolic and hormone profiles of male and female calf bearing cows in periparturient period. In the present study, 20 Brown Swiss (4-5 years old, 500-550 kg weighing) cows were used...
Conference Paper
This study aimed to investigate trace element levels, metabolic and hormone profi les of male calf bearing (MCB) and female calf bearing (FCB) cows in periparturient period. In the present study, 20 Brown Swiss (4-5 years old and 500-550 kg weighing) cow was used as animal material. Blood samples were collected on prepartum 21th day. According to b...
Conference Paper
The purpose of this study is to explore the protective eff ects of diff erent doses of rutin with the antioxidant and anti-infl ammatory properties on acute lung injury (ALI) induced by oleic acid (OA) in rats. 35 Sprague-Dawley male rats were randomly separated into fi ve groups: comprising control, rutin 150 mg, OA, rutin 75 mg+OA and rutin 150 m...
Conference Paper
The aim of this study was to evaluate the usefulness of inflammatory markers as a diagnostic and prognostic approach in neonatal calves with septicemia. The study material consisted of 13 neonatal calves with septicemia and 10 healthy neonatal calves. Blood samples were collected for acute phase reactants such as procalcitonin (PCT), haptoglobin (...
Conference Paper
This study evaluated the usefulness of hesperidin on serum alkaline phosphatase (ALP), aspartate (AST) and alanine (ALT) aminotransferase and liver Malondialdehyde (MDA), Glutathion (GSH), Superoxide Dismutase (SOD), Catalase (CAT) and Glutathion Peroxidase (GPx) in colistin (COL)-induced hepatototoxicity. Male rats were given intramuscular (i.m.)...
Conference Paper
In this case report, the pathological and clinical symptoms of Coenurosis-which was diagnosed on a simmental bull at the age of two from the region of Erzurum, brought to the clinic with the complaint of neurological symptoms- are aimed to investigate. During anamnesis, we reached the information of the implementations like injections of antibioti...
Article
The aim of this study was to evaluate the serum cardiac troponin I (cTnI) concentrations in weaned calves with moderate and severe bovine respiratory disease. Eighteen healthy weaned calves (group I), 18 weaned calves with moderate bovine respiratory disease (group II) and 18 weaned calves with severe bovine respiratory disease (group III) were inc...
Article
Full-text available
The aim of present investigation was to compare the efficacy of the steroids administered by inhalation and parenteral route in lambs with experimentally induced endotoxemia. In this study, 19 lambs were used at two months of age. Seven groups were designed as lipopolysaccharide (LPS) (n=3), LPS+budesonide (BUD) (n=3), LPS+BUD+enrofloxacin (ENR)+tr...
Article
Full-text available
Foot-and-mouth disease (FMD) can lead to myocarditis in young animals, but the age distributions of calves with myocarditis have not been described, nor the biochemical profile in these calves. In an area endemic with foot-and-mouth disease, calves less than 6 months of age in infected farms were examined for clinical lesions and abnormalities in r...
Article
The traumatic reticuloperitonitis (TRP) model was used to investigate the acute phase biomarkers (APBs) in the inflammatory response of dairy cows. Fourteen Swiss Brown cows were diagnosed with TRP based on the clinical findings, ferroscopy and ultrasonography as well as positive responses to pain tests. Four of the cows were necropsied and TRP was...
Conference Paper
Hemorrhagic bowel syndrome (HBS) is an intestinal disease that have been frequently seen in recent years and having high mortality rate in adult dairy cows. Other names given to HBS include jejunal hemorrhage syndrome, bloody gut, dead gut, and clostridial enteritis. HBS is characterized by sudden, progressive, and occasionally massive hemorrhage i...
Article
Full-text available
Feline coronavirus (FCoV) is a highly contagious virus that is ubiquitous in multicat environments and may induce oxidative stress. This virus commonly causes an asymptomatic infection, which can persist in certain individuals. Sporadically and unpredictably, FCoV infection leads to feline infectious peritonitis (FIP), a highly fatal systemic immun...
Conference Paper
Introduction: The purpose of this study was to determine the effects of some antioxidative vitamins and trace elements on some metabolic and postpartum reproductive profiles in dairy cows during periparturient period. Materials and methods: In this study, totally 20 clinically healthy Brown Swiss dairy cows (aged 4-5 years-old) in periparturient pe...
Conference Paper
Introduction: The study was aimed to evaluate the extent of myocardial injury with the severity of the disease by determining the serum cardiac troponin I (cTnI) concentrations in weaned calves with bovine respiratory disease. Materials and methods: Eighteen healthy weaned calves and 36 weaned calves with bovine respiratory disease were included in...
Conference Paper
Full-text available
Introduction: The purpose of this study was to determine the effects of some antioxidative vitamins and trace elements on some metabolic and postpartum reproductive profiles in dairy cows during periparturient period. Materials and Methods: In this study, totally 20 clinically healthy Brown Swiss dairy cows (aged 4-5 years-old) in periparturient pe...
Article
Canine tick-borne parasites have emerged in recent years, showing a wider geographic distribution and increased global prevalence. In addition to their veterinary importance, domestic dogs play an important role in the transmission cycles of some agents by acting as reservoirs and sentinels. This study investigated Babesia, Theileria, Anaplasma, an...
Article
The aim of this study was to investigate arginase activity, total oxidant capacity (TOC), total antioxidant capacity (TAC), and oxidative stress index (OSI) in cows with lung cystic echinococcosis (CE). The subjects were 20 cows with lung CE (parasitized group) and 20 healthy cows (control group). A significant increase in arginase activity, TOC, a...
Article
The aim of this study was to investigate arginase activity, total oxidant capacity (TOC), total antioxidant capacity (TAC), and oxidative stress index (OSI) in cows with lung cystic echinococcosis (CE). The subjects were 20 cows with lung CE (parasitized group) and 20 healthy cows (control group). A significant increase in arginase activity, TOC, a...
Article
Full-text available
Gentamicin is commonly used against gram-negative microorganisms. Its therapeutic use is mainly limited by nephrotoxicity. This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity in rats. The rats were treated with saline intraperitoneally (group I), 150...
Article
Full-text available
Gentamicin is commonly used against gram-negative microorganisms. Its therapeutic use is mainly limited by nephrotoxicity. This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity in rats. The rats were treated with saline intraperitoneally (group I), 150...
Conference Paper
Background: Maedi–visna virus (MVV) and caprine arthritis encephalitis virus (CAEV) are non-oncogenic retroviruses belonging to the genus Lentivirus. These viruses are called as small ruminant lentiviruses (SRLVs) including CAEV of goats and MVV of sheep. Both viruses are closely related with each other but they are genetically distinct lentiviruse...
Conference Paper
Full-text available
In recent years, numerous studies have been conducted on the reproductive effects of cyclooxygenase (Cox) inhibitors. Cox inhibitors are non-steroid anti-inflammatory drugs. They are often used to treat inflammation. Many studies have been carried on indicating that inhibition of cox-2 prevents implantation and ovulation in animals and humans. In t...