Akila Subasinghe

University of Sri Jayewardenepura · Electrical & Electronic Engineering

The ubiquitous integration of computer vision technologies has revolutionised various application domains, ranging from agriculture and transportation to healthcare and the military. In this context, real-time anomaly detection in video streams has emerged as a critical facet, particularly concerning the movement of vehicles and humans. Despite the...

Iris extraction has gained prominence due to its application versatility across many domains. However, achieving real-time iris extraction poses challenges due to several factors. While non-learning-based iris extraction methods are cost-effective and resource-efficient, they are outperformed by learning-based algorithms, which deliver superior acc...

Automated surveillance systems are becoming a critical requirement in maritime domain, due to the continuous expansion of maritime security threats. Although several automated systems have been developed, detection of maritime threats is becoming more challenging due to the constantly changing tactics adopted by seafarers to evade detection. Machin...

Accurate fetal Ultrasound (US) image segmentation facilitates advanced obstetric health care by enabling remote monitoring of expectant mothers. However, fetal US image segmentation is challenging due to distortions, motion artifacts, various imaging conditions and presence of maternal anatomy. Recent research work has proposed many methods towards...

Pupil localization extracts pupil center coordinates from images and videos of the human eye along with the pupillary boundary. Pupil localization essentially plays a major role in identity verification, disease recognition, visual focus of attention (VFOA) tracking, dementia cognitive assessment, and human fatigue detection. However, the process o...

Automated human chromosome segmentation and feature extraction aim to improve the overall quality of genetic disorder diagnosis by addressing the limitations of tedious manual processes such as expertise dependence, time-inefficiency, observer variability and fatigue errors. Nevertheless, significant differences caused by staining methods, chromoso...

Automated human chromosome segmentation and feature extraction aim to improve the overall quality of genetic disorder diagnosis by addressing the limitations of tedious manual processes such as expertise dependence, time-inefficiency, observer variability and fatigue errors. Nevertheless, significant differences caused by staining methods, chromoso...

Diagnosing and treating lung diseases can be challenging since the signs and symptoms of a wide range of medical conditions can indicate interstitial lung diseases. Respiratory diseases impose an immense worldwide health burden. It is even more deadly when considering COVID-19 in present times. Auscultation is the most common and primary method of...

Imaging is one of the key medical diagnostic tools to observe internal organs and soft tissues. One such tool is ultrasound scanning, which is highly utilized in gynecology and echo cardiogram. This is due to the number of advantages of ultrasound scanning, such as being non-invasive, free of radiation, economical and real-time. However, access to...

Accurate detection of the human metaphase chromosome centromere is a critical element of cytogenetic diagnostic techniques, including chromosome enumeration, karyotyping and radiation biodosimetry. Existing centromere detection methods tends to perform poorly in the presence of irregular boundaries, shape variations and premature sister chromatid s...

Accurate detection of the human metaphase chromosome centromere is an critical element of cytogenetic diagnostic techniques, including chromosome enumeration, karyotyping and radiation biodosimetry. Existing image processing methods can perform poorly in the presence of irregular boundaries, shape variations and premature sister chromatid separatio...

Matlab code files used in analysing the chromosome images

Matlab code files used in analysing the chromosome images together with Automatic Dicentric Chromosome Identifier (ADCI) software (V6.1)

Technological advancements have realized inexpensive standalone portable devices to perform ultrasound scans, which enables underfunded rural medical establishments to be equipped with ultrasound scanning facilities. However, the scarcity of medical experts to observe ultrasound scans is a major limiting factor. It is possible to overcome this limi...

We present a prototype software system with sufficient capacity and speed to estimate radiation exposures in a mass casualty event by counting dicentric chromosomes (DCs) in metaphase cells from many individuals. Top-ranked metaphase cell images are segmented by classifying and defining chromosomes with an active contour gradient vector field (GVF)...

A method for determining radiation exposure from chromosome abnormalities present in a specimen by determining the location or locations of the centromere of each chromosome in a cell in an image of a metaphase cell by segmentation of an accurately drawn chromosome centerline followed by selection of a longitudinal cross-section with the minimum wi...

A method for determining radiation exposure from chromosome abnormalities present in a specimen by determining the location or locations of the centromere of each chromosome in a cell in an image of a metaphase cell by segmentation of an accurately drawn chromosome centerline followed by selection of a longitudinal cross-section with the minimum wi...

Despite extensive analyses on the centromere and its associated proteins, detailed studies of centromeric DNA structure have provided limited information about its topography in condensed chromatin. We have developed a method with correlative fluorescence light microscopy and atomic force microscopy that investigates the physical and structural org...

Cytogenetic biodosimetry is the definitive test for assessing exposure to ionizing radiation. It involves manual assessment of the frequency of dicentric chromosomes (DCs) on a microscope slide, which potentially contains hundreds of metaphase cells. We developed an algorithm that can automatically and accurately locate centromeres in DAPI-stained...

Centromere localization in human metaphase chromosomes is an essential task in many cytogenetic diagnosis procedures. The centromere location can be utilized to derive information such as the chromosome type, polarity assignment etc. Methods available in literature yield unreliable results mainly due to high variability of morphology in metaphase c...

Detection and separation of overlapping and touching chromosomes is a critical issue in image analysis applications for cytogenetics where accurately segmented chromosomes are essential. We present a novel method of automatic pale path detection for all types of stained chromosome images. Optimum number of cut-points for each cluster of touching or...

The study of human metaphase chromosomes is an important aspect in clinical diagnosis of genetic disorders. Although many image processing techniques have been developed for chromosomal karyotyping to assist in laboratory diagnosis, they fail to provide reliable results in segmenting and extracting the centerline of chromosomes due to their shape v...

With the increasing use of Fluorescence In Situ Hybridization (FISH) probes as markers for certain genetic sequences, the requirement of a proper image processing framework is becoming a necessity to accurately detect these probe signal locations in relation to the centerline of the chromosome. Although many image processing techniques have been de...

A group of humans with diverse body dynamics and training backgrounds working on machines with different dynamics can be considered as a system of live systems. This paper presents a method that can be adopted to automate the evolution of an elite skill in a factory of workers operating a given type of machines to produce a given product through su...

Deployment of robots for humanitarian demining programs in former tropical battlefields has been a significant challenge due to the very complexity of the unstructured vegetated environments and the terrain conditions found inmost tropical minefields. This makes conventional navigation algorithms with high priority to collision avoidance,inappropri...