Akbar Ali Khan

Akbar Ali Khan
RMI Peshawar. · Neurosurgery

MBBS, FRCS Ed, FRCS Neurosurg

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22
Publications
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237
Citations

Publications

Publications (22)
Article
Background: In contrast to benign meningiomas, malignant meningiomas (MM) are rare and associated with an unfavourable prognosis. Reports on MM concern fairly small cohorts, often comprising less than 30 cases. Objective: To describe the outcome MM and identify factors that may influence survival. Methods: Pathology reports and clinical data o...
Article
Full-text available
Neurosurgery. 2018 Dec 19. doi: 10.1093/neuros/nyy610. [Epub ahead of print] Malignant Meningioma: An International Multicentre Retrospective Study. Champeaux C1,2,3,4, Jecko V3, Houston D4, Thorne L2, Dunn L4, Fersht N5, Khan AA4, Resche-Rigon M1. Author information 1 INSERM U1153, Statistic and Epidemiologic Research Center Sorbonne Paris Cité (C...
Article
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To describe the outcome of patients diagnosed with central nervous system haemangiopericytoma (HPC) or solitary fibrous tumour (SFT) and identify factors that may influence recurrence and survival. Between January 2000 and September 2016, a retrospective search identified 55 HPCs/SFTs. The patients underwent a total of 101 surgical resections and 5...
Article
Full-text available
Background: Idiopathic normal pressure hydrocephalus is predominantly a disease of the elderly. By its nature, many of those who present to clinic are in advanced old age with multiple comorbidities. Majority of patients treated are younger than 80 years old. We present the clinical outcomes and complication rates of patients over the age of 80 yea...
Article
Full-text available
Background Cerebrospinal fluid (CSF) leak following spinal surgery is a relatively common surgical complication. A disturbance in the underlying CSF dynamics could be the causative factor in a small group of patients with refractory CSF leaks that require multiple surgical repairs and prolonged hospital admission. Methods A retrospective case serie...
Article
Full-text available
To analyse the outcome of patients with WHO grade II meningioma and identify factors that may influence recurrence and survival. Between January 2007 and September 2015, a retrospective search identified 194 WHO grade II meningiomas at the National Hospital for Neurology and Neurosurgery, London. Survival methods were implemented. 31 patients (16 %...
Article
Study design: Systematic Review and Meta-AnalysisOBJECTIVE.: To identify whether intramuscular local anesthetic infiltration prior to wound closure was effective in reducing post-operative pain and facilitating early discharge following lumbar spine surgery. Summary of background data: Local anesthetic infiltration prior to wound closure may for...
Conference Paper
Full-text available
Cerebrospinal fluid (CSF) leak following spinal surgery is a relatively common surgical complication. A small group of CSF leak patients require multiple surgical repairs and prolonged hospital admission. Spinal CSF leaks are usually classically associated with symptoms of low intracranial pressure (ICP). However, there is a paucity of literature i...
Article
Full-text available
Langerhans cell histiocytosis is a rare disorder, with resultant bilateral sensorineural hearing loss unreported in adults. A 42-year-old man presented with 4 months of right-sided tinnitus and hearing loss treated initially as otitis media with effusion. He re-presented 5 months later with progressive bilateral hearing loss—sensorine...
Article
Abstract Tumours of the central nervous system can be metastatic or primary in origin, and can affect all age groups. The WHO grading system is most widely used to classify these tumours. CT and MRI imaging guide initial management and tissue diagnosis can be sought via open or image guided procedures. Prognosis depends on the type and location of...
Article
Objective Thyroid-stimulating hormone-(TSH-)expressing pituitary adenomas are a rare but important entity with a spectrum of clinical manifestations. There is currently no data to indicate whether a difference exists in the natural progression of active and silent TSH-expressing pituitary adenomas (defined by the presence or absence of clinical hyp...
Article
Plurihormonal pituitary adenomas are tumours that show immunoreactivity for more than one hormone that cannot be explained by normal adenohypophysial cytodifferentiation. The most common combinations in these adenomas include growth hormone (GH), prolactin (PRL) and one or more glycoprotein hormone sub-units (β-TSH, β-FSH, β-LH and αSU). The author...
Article
Intracranial germinoma is most commonly found in the pineal and suprasellar regions. The medulla oblongata and fourth ventricle are rare sites of primary germinoma, with only 12 previous patients reported, all from the Far East. To our knowledge, we report the first patient from Europe. A 25-year-old female of Afro-Caribbean origin presented with s...
Article
Full-text available
Introduction Pseudotumor cerebri secondary to all-trans retinoic acid in acute promyelocytic leukemia is a reported but rare complication of the therapy. Most cases improve following the discontinuation of all-trans retinoic acid. There is no published literature on how to manage such patients if severe symptoms of increased intracranial pressure c...

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