Ajeet Singh

• Ph.D.
• DBT-Senior Research Fellow at Indian Institute of Wheat and Barley Research

Addressing global hidden hunger, particularly in women of childbearing age and children under five, presents a significant challenge, with a focus on iron (Fe) and zinc (Zn) deficiency. Wheat, a staple crop in the developing world, is crucial for addressing this issue through biofortification efforts. While extensive research has explored various a...

Cancer is one of the leading causes of death worldwide. The advent of modern drug-targeted therapies has undeniably improved cancer patients’ management. However, advanced metastasized cancer remains untreatable. Hence, the continued search for safer and more effective chemoprevention and management are still needed to improve the efficiency of tre...

Herbal medications are commonly used for clinical purposes, including the treatment of cardiovascular conditions. Cardiovascular diseases (CVDs), hypertension, and obesity are among the major causes of death globally. The treatment of CVDs, hypertension, and obesity using modern medicines is very expensive. On the other hand, various medicinal plan...

Plant based Nanoparticles for treatment of cancer, a noval strategy for target based treatment of disease, synthesis of nanoparticles and pathways at cellular level.

Childhood diseases occur chiefly among children, and one bout of infection usually provides lifelong immunity against further attacks. Few exanthematous viral infections considered in this chapter are measles, chickenpox, German measles, and other viral infections that produce skin eruptions and mumps. Identifying plant-based natural novel antivira...

Antiviral effects of phytochemical, resolving the respiratory disorders by botanical extracts.

The launch of our successful chapter publication in Coronavirus Drug Discovery, Elsevier.

Several medicinal plant species have been recorded globally to treat a myriad of diseases. In medicinal plants, there are various phytochemicals, that is, alkaloids, quinones polyphenols, terpenes, proanthocyanidins flavonoids, saponins, lignins, tannins, polysaccharides, steroids, thiosulfonates, and coumarins were found prominent, which have been...

The main goal of this study was to assess the potential proteins of goat milk (i.e. α‐s1‐casein, α‐s2‐casein, β‐casein, κ‐casein, α‐lactoglobulin and β‐lactalbumin) as precursors of antimicrobial peptides (AMPs). Bioinformatics tools such as BIOPEP‐UWM (enzyme action) were used for the in silico gastrointestinal digestion via a cocktail of pepsin,...

Phytochemicals are natural active ingredients that are occurring in plants. In the pursuit for novel biomolecules, the recovery of bioactive composites from plants, as well as their quantitative and qualitative evaluation, is critical. In the discovery and characterization of bioactive compounds, plant extraction and separation remain a critical co...

The Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery examines the applications of bioactive molecules from a health perspective, examining the pharmacological aspects of medicinal plants, the phytochemical and biological activities of different natural products, and ethnobotany and medicinal properties. Moreover, it pr...

The Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery examines the applications of bioactive molecules from a health perspective, examining the pharmacological aspects of medicinal plants, the phytochemical and biological activities of different natural products, and ethnobotany and medicinal properties. Moreover, it pr...

Medicinal plants have been necessary to conventional and non-customary types of prescriptions dating back to somewhere around 5000 years ago. Researchers progressively depend on current logical techniques and proof-based medication to demonstrate the viability of herbal medicines and spotlight on a better comprehension of the systems of their activ...

Wheat is the second most important staple food crop after rice and is primarily consumed by the global population to meet its daily energy and protein requirements. Hexaploid, i.e. T. aestivum, and tetraploid, i.e. T. durum, are commonly used to make various end products. Different end products require different qualities. The quality required to m...

Curcuma longa L. belonging to the Zingiberaceae family is a well-known medicinal plant known to possess variety of antimicrobial activities. The extracts of C. longa rhizome, curcumin and turmeric oil have antimicrobial activity against bacteria, viruses and fungi. Apart from antimicrobial activity, curcumin is known for other pharmacological prope...

The emerging development of technology and increasing demand of nanomaterials has raised unparalleled expansion of research for the development of high production and sustainable synthesis methods which can provide nanomaterials with desired characteristics. The well-established physico-chemical methods which have various limitations, biological me...

Jaundice is not a disease but it is a problem related to the liver and bladder. The excretion of food is done through the process of metabolism by the liver. As if there is any imbalance in the bilirubin levels the chances of hepatic problems arises. Our traditional knowledge from grand-grand-parents is very useful which is giving a boost to resear...

This chapter has covered the fungal based nanoparticles synthesis and medicinal benifits of Silver and Gold nanoparticles treatment. The book is composed with such wide information related to plant based microbe based medicinal effects and benifits. For details Book your copy now 👍

This volume sheds new light on the immense potential of medicinal plants for human health from different technological aspects. It presents new research on bioactive compounds in medicinal plants that provide health benefits, including those that have proven especially effective in treating and managing diabetes mellitus and hypertension. It looks...

Bacteria can be opposed to numerous antibiotics and we can swiftly resemble a time when antibiotics will not work properly on a few bacterial infections that face global health concern. Medicinal plants are gaining renowned devotion in scientific communities at present due to their dependable pharmacological deportment and affordability to ordinary...

Human immunodeficiency virus is recognized as a causative agent of the acquired immunodeficiency syndrome (AIDS) that comprises a serious concern globally for decades. Even after 40 years of the discovery of HIV, not many things have changed in the history of HIV/AIDS. Despite significant progress, mysteries related to HIV infection remain to be ad...

The combined effect of iron (Fe) and zinc (Zn) starvation on their uptake and transportation and the molecular regulatory networks is poorly understood in wheat. To fill this gap, we performed a comprehensive physiological, biochemical and transcriptome analysis in two bread wheat genotypes, i.e. Narmada 195 and PBW 502, differing in inherent Fe an...

In plants, iron (Fe) & zinc (Zn) uptake and transportation from the rhizosphere to the grain is a critical process regulated by complex transcriptional regulatory networks. However, understanding the combined effect of Fe & Zn starvation on their uptake and transportation and the molecular regulatory networks that control them lack in wheat. Here,...

The dairy industry is one of the many industries that are concerned with the occurrence of pathogenic bacteria, where a pathogenic microbe further leads to a destructive influence on human health. The food-borne outbreaks of diseases from bacterial pathogen contamination and chemicals are very common around the world. Improper pasteurization and ev...

The dairy industry is one of the many industries that are concerned with the occurrence of pathogenic bacteria, where a pathogenic microbe further leads to a destructive influence on human health. The food-borne outbreaks of diseases from bacterial pathogen contamination and chemicals are very common around the world. Improper pasteurization and ev...

The dairy industry is one of the many industries that are concerned with the occurrence of pathogenic bacteria, where a pathogenic microbe further leads to a destructive influence on human health. The food-borne outbreaks of diseases from bacterial pathogen contamination and chemicals are very common around the world. Improper pasteurization and ev...

A vast majority of the world’s population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemic...

‘HerbalInformatics’isacombinedtermusedforunravelingthepotential‘herbal’leadsagainsttargetedvirulencefactorsofbiologicalimportance,utilizing‘informatics’toolsi.e.,searchengine,softwares,databasesandservers.ThemainideabehindthefieldofHerbalInformaticsistoamalgamateinformaticsbranchesi.e.bioinformatics,chemoinformatics,immunoinformatics,etc.withHerbal...

Medicinal plants have been necessary to conventional and non-customary types of prescriptions dating back to somewhere around 5000 years ago. Researchers progressively depend on current logical techniques and proof-based medication to demonstrate the viability of herbal medicines and spotlight on a better comprehension of the systems of their activ...

The peptic ulcer is a widespread and common health problem around the world. The major causes include generation of free radicles, decrease in mucosal defense factor, or increase in mucosal injurious factors. Various plants and their products have been known to prevent or reduce peptic ulcers. Natural products from plants are a rich resource used f...

Dairy industry is the main party concerned with the presence of pathogenic microbes, where failure to sight a pathogenic microbe may lead to a terrible impact. The food-borne outbreaks from microbial contamination and chemicals are very common around the world. Foods during this commodity are typically consumed after pasteurization. However imprope...

Aegle marmelos is native to India. The monotypic genus Aegle belongs to family Rutaceae has several neutraceutical and medicinal properties which are being used in traditional medicinal systems to cure a variety of diseases. The plant has been extensively studied for its medicinal and pharmacological properties by advanced scientific techniques and...

Microbes play crucial role in bioremediation of hydrocarbon contaminated soil and solid waste. In this study, poly-aromatic hydrocarbons resistant fungi were isolated from soil samples of different areas including Delhi-NCR and Meerut city (Uttar Pradesh), the bioremediation of hydrocarbons like naphthalene and pyrene by these isolates were charact...

Polyaromatic hydrocarbons remediation

Green synthesis of metal nanoparticles has various advantages over chemical synthesis. Green synthesized nanoparticles are known for their less toxic nature. Beside the toxicity, these are also more stable and eco-friendly. This cost effective approach is utilized in present study for the green synthesis of Titanium dioxide nanoparticles using Sonc...

Syzygium cumini commonly known as a "Jamun" having promising therapeutic values. It is a large evergreen tropical tree. It is belongs to the family Myrtaceae. S. cumini is also known as Jamun or black plum or jambolan. S. cumini showed various phytoconstituents such as tannins, alkaloids, steroids, flavonoids, terpenoids, fatty acids, phenols, mine...

Piper longum Linn. (family piperaceae) is popularly known as long pepper. It is widely distributed in the tropical and subtropical regions of the world, throughout the Indian subcontinent, Sri Lanka, Middle Eastern countries and the Americas. The root and stem part of the P. longum, has been used for various Ayurvedic and Unani system of medicine....

Leucas indica belongs to the family Lamiaceae commonly known as Guma, Tumba, Dandokalos. Traditionally, it is used in Garhwal region of Uttarakhand as a wound healer. The leaves of this plant are squeezed and placed on wounds to obtain wound healing. Leaves are also used as vermifuge, stomachic, sedative and in sores. This plant is widely used in p...

Sida rhombifolia Linn. (family- Malvaceae) is a medicinal plant of tropical and warm regions. Sida rhombifolia showed antibacterial, antifungal, anti-malarial, antioxidant, insecticidal, antidiarrheal, anti-inflammatory, antiplasmodic, and cytotoxic properties. In traditional system of medicine it is useful for various diseases such as for treating...

The use of the traditional plants combating microbial diseases is becoming the focus of numerous studies. About 3.4 billion peoples in the developing world depend on plant based traditional medicines natural products have been an integral part of the ancient traditional medicine systems (e.g. Chinese, Egyptian and Ayurvedic). Plants have unlimited...

As the world population is increasing day by day it is also need to be increasing the production of food. If the population will reach up to 9.1 billion by 2050 then the production of food need to be increase up to 70 % which is more than double of production of the world. To achieve this goal to feed up the population at that era; it the major cha...

The use of the traditional plants combating microbial diseases is becoming the focus of numerous studies. About 3.4 billion peoples in the developing world depend on plant based traditional medicines natural products have been an integral part of the ancient traditional medicine systems (e.g. Chinese, Egyptian and Ayurvedic). Plants have unlimited...

In India, FSSAI set a guideline for Industries to maintain the quality of different food products. They provide quality limits of different parameters like Total Bacterial Count, Total Fungal Count, Coliform count and Pathogens. When a food product launched into the market it will be certified that; this product is in Quality limits. In this paper...

The comprehensive survey information as provided in this review on Sida spinosa Linn traditional uses, ethanobotanical aspects, phytochemistry and pharmacology. The plant has a variety of traditional uses. Leaves are reported to possess demulcent, refrigerant properties, and are useful in cases of gonorrhoea, gleet and scalding urine. They are brui...

Achyranthes aspera commonly known as Apamarga is herbal medicinal plant distributed throughout India and is used traditionally in wound healing, piles, skin diseases and dental problems. Different constituents are present in different parts of Achyranthes aspera like saponin, oleanic acid, achyranthine, ecdysterone, alkaloids, flavonoids, steroids...

The inclusive information is provided in present review on traditional uses, antimicrobial activity and pharmacology of Moringa oleifera Lam. It is commonly known as 'drumstick tree'. M. oleifera is alternative tonic, astringent, emollient, aphrodisiac etc. Bark of this plant is considered as cooling. Seeds of this plant are considered as aphoradis...

Viola odorata Linn. is belongs to the family violaceae. It is popularly known as Sweet Violet, English Violet, Common Violet, or Garden Violet and Gulbanafsa in Hindi. V. odorata is commonly used as remedy for coughs, sore throat, hoarseness and tonsillitis. It is valued as an expectorant, antioxidant, diaphoretic, antibacterial, antipyretic, diure...

The inclusive information is provided in this review on traditional uses, antimicrobial activity, phytochemistry and pharmacology of S. cordifolia. In ayurveda it is commonly known as bala. According to Ayurveda, the plant is tonic, astringent, emollient, aphrodisiac and useful in treatment of respiratory system related troubles. S. cordifolia is a...

Malva parviflora Linn. has shown its pharmacological potential in different ailments. Leaves are used in the management of wounds and swelling. A lotion made from the leaves is used to treat bruises and broken limbs. The leaves of M. parviflora are used for drawing swollen, inflamed purulent wounds. Pharmacological studies shown that M. parviflora...

Ethno-botanical and traditional uses of natural compounds, mainly of plant origin established much interest as they are well tested for their efficacy and generally believed to be safe for human use.The extracts of differet parts might be added value in the scientific evalution of medicinal application of C. Maxima. Extensive literature survey reve...

Barleria prionitis linn.is a widely dispersed indigenous plants throughout the Indian subcontinent. In the Ayurvedic medicine of the India, it has a significant place due to its biological and pharmacological activities. The various parts of B. prion it is are widely used to cure an array of ailments by different ethnic communities. The whole plant...

The antibacterial and phytochemical investigation of Barleria lupulina Lindl. aerial parts extracts were examined against common respiratory tract pathogens i.e., Streptococcus pneumoniae (MTCC 655), Staphylococcus aureus (MTCC 1144), Pseudomonas aeruginosa (MTCC 2474), Streptococcus pyogens (MTCC 442), Haemophillus influenzae (MTCC 3826). The plan...

Tephrosia purpurea is a wild herb belongs to the family fabaceae and commonly known as sharpunkha. It is distributed among India, Australia, China, Sri Lanka up to 400 m to 1300 m altitude. It occurs naturally in the waste places along the road sides and it prefers to grow in dry, gravelly or rocky and sandy soil. It is being used as folk medicine...

The comprehensive information is provided in this review on Trichosanthesanguina(syn T. cucumerina) traditional uses, ethnobotanical aspects, phytochemistry and pharmacological uses. All-embracing literature survey given way to the promising pharmacological activities of T. cucumerinai.e. antibacterial, antifungal, anthelmintic, anti-fertility, ant...

Parthenium hysterophorus (Linn.) is violent everywhere annual, herbivorous weed. It is commonly known as congress grass or gajar ghas. P. hysterophorus shown several hazardous effects on human health and livestock. It reduces the crop production due to its allelopathic effect. In spite of these drawbacks P. hysterophorus is traditionally recognized...

BIOGENIC SYNTHESIS OF PHYTO-EXTRACT IMITATIVE SILVER NANOPARTICLS (AgNPs) AND ITS ANTIMICROBIAL POTENTIAL FOR PHARMACOLOGICAL APPLICATIONS Ajeet Singh1*, Vinay Mohan Pathak, Neelesh Babu and Navneet 1Department of Botany and Microbiology, Gurukul Kangri University Haridwar 249404, India ajeetchoudharygkv@gmail.com (corresponding author) Abstract:...

India has a rich heritage of knowledge on plant based drugs both for exploit in preventive and curative medicine. Aromatic plants have played key roles in the lives of tribal peoples living in the Uttarakhand (India) by providing products for both food and medicine. Their primary health care system is depending on traditional knowledge of medical p...

The antimicrobial potential of Barleria prionitis Linn. (Aerial parts) were evaluated against common respiratory tract infections causing bacterial and fungal pathogens. The pathogens used in this study were Streptococcus pneumoniae (MTCC 655), Staphylococcus aureus (MTCC 1144), Pseudomonas aeruginosa (MTCC 2474), Streptococcus pyogens (MTCC 442),...

Cellulose is an abundant natural biopolymer on earth and most dominating agricultural waste. Cellulosic biomass is a renewable and abundant energy source with great potential for bioconversion to value-added bio-products. Cellulose can be degraded by cellulase producing bacteria which is most important biocatalysts for the industrial process. Under...

The antimicrobial activity and phytochemical investigation of seeds extracts of Citrus maxima Burm. was examined against common respiratory tract pathogens. The pathogens used in this study were Streptococcus pneumoniae (MTCC 655), Staphylococcus aureus (MTCC 1144), Pseudomonas aeruginosa (MTCC 2474), Streptococcus pyogens (MTCC 442), Haemophillus...

The antibacterial activity of seeds extracts of Citrus maxima Linn was examined against common respiratory tract infections causing pathogens. The pathogens used in this study were Pseudomonas aeruginosa (MTCC 2474), Streptococcus pneumoniae (MTCC 655), Staphylococcus aureus (MTCC 1144), Streptococcus pyogens (MTCC 442) and Haemophillus influenzae...