Ajay kumar Sahi

Ajay kumar Sahi
Indian Institute of Technology (Banaras Hindu University) Varanasi | BHU · School of Bio-Medical Engineering

Ph.D IIT (BHU) Varanasi
Senior Project Associate

About

22
Publications
4,060
Reads
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106
Citations
Introduction
Dr. Ajay Kumar Sahi received Ph.D. from school of biomedical engineering, IIT (BHU), Varanasi, in March 2022 in the field of tissue engineering. Dr. Ajay pursued B.Tech in biotechnology and M. Tech in biotechnology from SVPUA&T, Meerut and IIT Guwahati, respectively. Currently, he is working as senior project associate (SPA) at sophisticated analytical technical help institute-Banaras Hindu University (SATHI-BHU), Varanasi. He is In-charge of Laser scanning super resolution microscopy system.

Publications

Publications (22)
Article
Bone tissue engineering is an emerging technology that has been developed in recent years to address bone abnormalities by repairing, regenerating and replacing damaged/injured tissues. In present work, we report the fabrication and characterization of porous luffa-based composite scaffolds composed of Luffa cylindrica (sponge gourd) powder (LC)/hy...
Article
Full-text available
Cellulose, the most abundant polysaccharide on earth, can be obtained from various sources including the cell wall of plants and woods, bacteria, algae, and tunicates. However, the cellulose obtained from bacteria known as bacterial cellulose or bacterial nanocellulose (BC) has gained major popularity due to its simple production process, non–toxic...
Article
Full-text available
Chronic elevation of sugar and oxidative stress generally results in development of advanced glycation end products (AGEs) in diabetic individuals. Accumulation of AGEs in an individual can give rise to the activation of several pathways that will ultimately lead to various complications. Such AGEs can also be prepared in an in vitro environment. F...
Article
Cryospray is a process of destructing cancerous lesions occurring on the skin. Cryogen is sprayed on the affected area and ablation is achieved through rapid freezing of the cell. Metabolic heat generation, blood perfusion and thermal properties of tissue affect the heat sink in the skin. However, these terms are neglected in in-vitro experiments b...
Article
Bone defects in the craniomaxillofacial (CMF) region occur as a result of trauma, cancer excisions, congenital defects and deformities. CMF bone reconstruction is challenging due to anatomical complexity, functionality and aesthetic conditions. Bone grafting is the current standard approach to reconstruct CMF injuries. However, it possesses certain...
Article
Solid supported catalysts such as amines has high demand for chemical fixation of CO2 into commodity chemicals. Here, we demonstrate an accelerated platform for 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU)-ionic liquids (ILs) catalyzed CO2...
Article
Tissue engineering is a promising approach to overcome the severe worldwide shortage of healthy donor corneas. In this work, we have developed a silk-gelatin composite scaffold using electrospinning and permeation techniques to achieve the properties comparable to cornea analog. In particular, we present the fabrication and comparative evaluation o...
Article
Full-text available
In the current scenario, there are negligible or no approved anti-neurodegenerative therapies globally; only the conventional drugs provide very short-term relief. For centuries, due to multi-component and multi-target approaches of herbal or natural medicines have been used to treat various neurodegenerative like senile dementia and Alzheimer’s di...
Article
Full-text available
Coronavirus disease (COVID) is highly contagious, and negligence of it causes high morbidity and mortality globally. The highly infectious viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was abbreviated as COVID-19 (Coronavirus disease 2019) by World Health Organization first time on February 11, 2020, and later...
Article
The present study reports for first time the blending of psyllium husk (PH) powder/gelatin (G) in the polymer‐rich composition of polyvinyl alcohol (PVA) to make an electrospinnable solution. The composite was prepared in 3 different ratios viz., 100% (wt/wt) (PVA + PH), 75% + 25% (PVA + 75PH + 25G) (wt/wt) and 50% + 50% (PVA + 50PH + 50G) (wt/wt)...
Article
The primary goal of this study is to highlight the rheological and mechanical properties of a new blend composed of naturally-derived hydrogel materials- psyllium husk (PH) and gelatin (G) for its potential use in three-dimensional (3D) printing technology. The mixtures were prepared at various weight ratios of 100PH, 75PH + 25G and 50PH + 50G. A s...
Article
Gelatin is a hydrolysed form of collagen which is categorised as type A (acid hydrolysed) or type B (base hydrolysed), based on method of hydrolysis. In this work, we have studied the comparative properties of electrospun nanofibers of gelatin A (GA) and gelatin B (GB) prepared using a ternary solvent (glacial acetic acid/ethyl acetate/water). In a...
Chapter
Advancement in lifestyle and exponential population growth have evoked competitiveness and struggle for survival, resulting in the elevated levels of physiological stress that notably shows correlation with the rising health disparities within the population. Sustained level of stress based on environmental factors, gender inequalities, competitive...
Article
Existing myoelectric prostheses can provide solutions to amputees for performing activities of daily livings. However, there are several issues with these prostheses (1) performance are affected mainly by sweat, electrode shift, motion artifact, interference, etc. (2) are expensive (3) have complex control schemes. This paper presents an affordable...
Article
A wearable sensor was fabricated to provide simultaneous electromyography (EMG) and force myography (FMG) information , from the same muscle location for controlling multi-functional hand prosthesis. The typical mechanical arrangement of the sensor constitutes silver electrodes and a force-sensitive resistor embedded inside the sensor chassis for d...
Article
Biocompatible soy protein isolate/silk fibroin (SPI/SF) nanofibrous scaffolds were successfully fabricated through electrospinning a novel protein blend SPI/SF. Prepared nanofibers were treated with ethanol vapor to obtain an improved water-stable structure. Fabricated scaffolds were characterized through scanning electron microscopy (SEM), Fourier...
Article
Full-text available
Psyllium husk or isabgol contains xylan backbone linked with arabinose, rhamnose, and galacturonic acid units (arabinoxylans). In this study, we demonstrate the fabrication and characterization of a macroporous three-dimensional (3D) composite scaffold by mixing psyllium husk powder (PH) and gelatin (G) in different ratios, viz.100 PH, 75/25 PH/G,...
Article
Full-text available
Human milk is considered as a complete food since it constitutes all the major essential nutrients, minerals, and vitamins to sustain the life. Human milk is responsible for the evolution of an efficient immune system and organ development as well as acts as a protective barrier against inflammation and infection. In addition, it is known to be a g...
Article
Full-text available
In the present study, we propose a platform for topical wound dressing material using a polydimethylsiloxane (PDMS) scaffold in order to enhance the skin healing process. In vitro co-culture assessment of epidermal-origin mouse B16-F10 melanocyte cells and mouse L929 fibroblast cells in three-dimensional polymeric scaffolds has been carried out tow...
Chapter
Drug delivery is defined as administration of drug component inside the body, and the system adopted for the same is known as drug delivery system. Advancements in the drug delivery system are gaining more attention and popularity due to the use of nanoformulations that enables efficient, effective and specific targeting of the drug. Several drug c...

Questions

Questions (2)
Question
If we dissolve essential fatty acids in DMSO or ethanol solvents, do they affect these fatty acids anyhow ??
Question
Please help me in finding the absorption spectra (wavelength, nm) of following 
1. 5-Hydroperoxy ETE
2. 12- Hydroperoxy ETE
3. 15- Hydroperoxy ETE
4. 5- Hydroperoxy EPE
5. 14- Hydroperoxy DHA
6. PGG2
7. 15-(R)-Hydroxy ETE
8. 18- Hydroperoxy EPE
9. EET

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Project (1)