Aïmen Abbassi

• Master of Pharmacy
• Medical Professional at Hôpital Charles-Nicolle

The exponential rise of bacterial resistance poses a threat to antibiotic efficacy, with a great impact on public health. This study aims to analyze the correlation between antibiotic consumption and the emergence of bacterial resistance. Conducted retrospectively at Charles Nicolle Hospital in Tunis, Tunisia, from 2010 to 2022, this study was base...

Introduction: Au cours de sa pratique, le pharmacien est confronté à des situations pouvant poser des problèmes éthiques. Il doit alors prendre des décisions en se basant sur des connaissances scientifiques ainsi que sur les principes de la bioéthique. Objectif : Évaluer les attitudes des pharmaciens face à des dilemmes éthiques particuliers. Métho...

The exponential rise of bacterial resistance poses a threat to antibiotic efficacy, with a great impact on public health. This study aims to analyze the correlation between antibiotic consumption and the emergence of bacterial resistance. Conducted retrospectively at Charles Nicolle Hospital in Tunis, Tunisia from 2010 to 2022, this study was based...

This study explores a nanoemulsion (NE)-based gel incorporating Tunisian Pituranthos tortuosus essential oil, with a focus on its wound-healing potential. The essential oil, extracted via hydrodistillation, underwent GC-MS analysis for compositional verification. The physicochemical characterization included dynamic light scattering (DLS), transmis...

Citrus aurantium fruit peel is a substantial source of polyphenols and flavonoids. An ultrasound-assisted procedure was used in this work for the extraction of these compounds from Citrus aurantium peels and additional steps of purification were carried out to yield flavonoid-enriched extract. Box–Behnken design was applied to optimize the ultrasou...

Objectives: Parenteral nutrition (PN) offers a quality therapeutic option when enteral feeding is non-tolerated or impossible. However, it can be associated with an increased risk of medical errors, especially in sensitive populations such as newborns. This study aimed at determining the impact of the implementation of a computerized physician orde...

Background and importance During the COVID-19 pandemic, the management of medical devices was foreseen by repetitive and unforeseen breaks. To optimise management a risk analysis is necessary. Aim and objectives The present study aimed to determine risks related to the medical devices management processes in our teaching hospital according to a fa...

Background and importance According to the World Health Organization, 80% of the world’s population uses medicinal plants. This allopathy alternative constitutes an accessible and inexpensive source of medicines. However, it is not without risks. Aim and objectives This study aimed to: (1) assess the prevalence of the use of medicinal plants, (2)...

Background Healthcare is not as safe as it should be and medication error remains a significant source of preventable morbidity and mortality among patients. Objectives To present a failure mode and effect analysis (FMEA) of the medication management process in the pharmacy of the largest teaching hospital in Tunisia. Secondly, to examine the vali...

Objective The objective of this study was to assess the level of Vitamin K antagonist (VKA) therapy knowledge among VKA newly treated patients. Methods Questionnaire-based interviews were administered in a university hospital to VKA newly treated patients covering both cognitive (i.e. indication, route of administration, treatment monitoring and s...

Background and importance Parenteral nutrition (PN) is an intravenous nutrition technique commonly used in intensive healthcare units. Considering the lack of marketed mixtures for the neonatal population, the preparation of PN is an essential, but complex and high risk hospital activity. Aim and objectives To analyse the risks related to the proc...

Introduction The preparation of neonatal parenteral nutrition mixtures is a complex and high-risk activity. Our study aimed to analyze the risks associated with the process of preparing parenteral nutrition bags in the pharmacy department of a university maternity and neonatology center. Methods A failure mode, effect and criticality analysis (FME...

Background Albumin is a drug that is challenging to manage due to its high cost and controversial use in clinical practice. This study aims to determine, in a university hospital gastroenterology department, the frequency and the economic impact of inappropriate human albumin prescriptions in terms of indication based on consensus. Materiel and me...

This study aimed to determine phytochemical contents, antibacterial properties, and antibiotic modulating potential of Punica granatum leaf extracts: hexane, chloroform, ethyl acetate, ethanol, and aqueous extracts as well as an extract enriched with total oligomer flavonoids (TOFs). The TOF extract contained the highest value of phenols and flavon...

Background and importance Albumin is a widely used medication for the treatment of critically ill patients, such as those with cirrhosis, burns patients and neonatal patients. However, its management is still a real challenge because of its high cost and controversial uses. Aim and objectives The aim of the study was to determine the frequency of...

Background and importance In the case of non-centralised sterilisation units, there is a lack of understanding of the effectiveness of different steam sterilisation processes. In such cases, the risk of failure is major. This may lead to the non-sterility of treated medical devices which can affect patient health. Aim and objectives The aim of the...

Résumé Introduction Le fractionnement des comprimés est une pratique bien établie qui permet de réaliser des économies. Cependant, elle n’assure pas nécessairement l’uniformité de la masse des fractions, en particulier pour les médicaments à marge thérapeutique étroite. L’objectif de cette étude est d’analyser l’uniformité de masse des fractions i...

Background Parenteral nutrition in neonatal intensive care units is a daily activity with extreme risks. These risks are mainly related to the immaturity of neonates, a sensitive population. The computerisation of the process of prescription is a promotional tool to reduce the risks. Purpose This study aimed to assess the interest in implementing s...

Background Hypoglycaemia is the antidiabetic drugs’ major side effect, especially for insulin and insulin secretagogues. Few observations in real-life iatrogenic hypoglycaemia studies on type 2 diabetes have been carried out. Purpose To assess iatrogenic hypoglycaemia frequency on type 2 diabetic patients and to measure its impact on quality of li...

Enzyme-assisted extraction has emerged as an attractive green, cost-effective and high bioactive yielding technology by which desired bioactives with preserved or better efficacy are released. In the present study, the ability of cellulase, hemicellulase and their binary mixture (cellulase:hemicellulase; 1:1) in improving the extraction of essentia...

Background Hypoglycaemia may result in significant anxiety and worry or even a fear of hypoglycaemia, which may have clinical implications for diabetes management. Purpose This study aimed to assess the fear of hypoglycaemia in patients with diabetes type 2, to identify factors affecting this and to seek correlation with treatment adherence. Mate...

Background Our hospital mission is to insure patient safety and quality of care. Evaluation and improvement of drug management processes are essential to prevent and limit iatrogenic events. Purpose The present study aimed to assess the risk of drug management processes in a cardiology inpatient unit according to a proactive analysis: failure mode...

Introduction Le diabète est une maladie chronique avec une incidence et une prévalence en ascension permanente dans le monde. L’hypoglycémie représente l’effet indésirable majeur des médicaments antidiabétiques en particulier les insulines et les insulino-sécrétagogues. Rares sont les études d’observation en vie réelle sur les hypoglycémies iatrogè...