Ahmet Kahraman

Usak University · Department of Biology

The genera Geranium and Erodium (Geraniaceae) have been documented to possess diverse ethnopharmacological uses, including diabetes mellitus. Relevant to their ethnopharmacological use, the current study aimed to evaluate the α-glucosidase, α-amylase, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzyme inhibitory activity of ethano...

The genera Geranium and Erodium (Geraniaceae) have been documented to possess diverse ethnopharmacological uses, including diabetes mellitus. Relevant to their ethnopharmacological use, the current study aimed to evaluate the α‐glucosidase, α‐amylase, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzyme inhibitory activity of ethano...

Objective: The aim of this study was to examine the in vivo wound healing potential of Salvia huberi Hedge (endemic to Turkey) on excision and incision wound models in diabetic rats. Method: Male Wistar albino rats, 3-4 months old and weighing 180-240g were used. The animals were randomly divided into five groups including Control, Vehicle and Fito...

Objective: The aim of this study was to examine the in vivo wound healing potential of Salvia huberi Hedge (endemic to Turkey) on excision and incision wound models in diabetic rats. Method: Male Wistar albino rats, 3-4 months old and weighing 180-240g were used. The animals were randomly divided into five groups including Control, Vehicle and Fito...

The sterol, amino acid, mineral, total phenolic, and total flavonoid contents, and the antioxidant, antimicrobial, and antibiofilm activities of Salvia candidissima subsp. candidissima mericarps were investigated. The mericarps were collected in the province of Bayburt, Turkey. Gas chromatography was used for sterol analysis, Prominence ultra-fast...

Biofilm-associated infections cause important health problems all over the world. Because of the resistance to antimicrobials and their possible side effects, researchers' attention has been focused on plant extracts and their components. The aim of this study is to evaluate the antimicrobial and antibiofilm potentials of Salvia microstegia Boiss....

Abstract Chromosomal data and karyological relationships provides valuable contributions to understanding speciation and karyotypic phylogeny. Because of the large number of species, wide distribution, morphological differences and chromosomal variations, Geranium is an important genus for determining the relationship between chromosomal alteration...

In this study, it was aimed to determine the chromosome number of 21 Salvia L. species, to determine chromosome morphology, to reveal karyotype analysis in detail and to contribute to the cytotaxonomy of Salvia. In this context, the results are as follows: (i) the first report for the number of chromosomes of ten species, namely S. corrugata Vahl....

Aim: To determine the antiproliferative and cytotoxic activities of Geranium and Erodium species against human cancer and noncancer cell lines, respectively. Methods: Twenty-one species of Geranium and Erodium were extracted and screened against cancerous and noncancerous human cell lines. Results: In a dose-response manner, G. glaberrimum, G....

The phytochemical contents of Salvia virgata mericarps and the antioxidant and antimicrobial activities of its ethanol extract were studied for the first time. S. vir-gata mericarps were collected in the province of Trabzon, Turkey. Chemical analyses were performed using chromatographic methods. The total phenolic and fla-vonoid contents and antiox...

The anti-gout effect of Erodium birandianum Ilarslan & Yurdak. was investigated through xanthine oxidase (XO) inhibition using in vitro and in silico experiments. The ethanol extract of E. birandianum (EB) with 82.26 ± 0.10 % of XO inhibitory activity at 100 μg/mL was sequentially fractionated. The extract and active fractions were analyzed using L...

In the current work, the ethanol extracts of (36 samples from various locations) 21 species of Geranium were investigated for their tyrosinase (TYR) inhibitory and antioxidant activity. G. glaberrimum (GG) (31.41 ± 1.11%), G. macrostylum (31.15 ± 1.35%), and G. lasiopus (30.01 ± 0.09%) had the highest inhibition against TYR, which were proceeded to...

Purpose: Nonhealing wounds are a serious problem of diabetic patients. Salvia species are traditionally used for the treatment of wounds. The aim of the study was to investigate the effects of ointment prepared with ethanol extract obtained from the aerial parts of Salvia hypargeia, an endemic plant from Turkey, on diabetic rat incisional and excis...

Salvia (sage) is a species rich and medicinally important genus. Species-level identification is usually very difficult, particularly in closely related species. Here, we investigated nutlet micromorphological characteristics of 51 taxa belonging to S. subg. Salvia, S. subg. Sclarea and Salvia verticillata clade (S. subg. Heterosphace) by stereo bi...

The fatty acid, sterol, and tocol compositions, mineral, total phenolic, and flavonoid contents, and antioxidant and antimicrobial activities of Salvia longipedicellata Hedge (endemic) mericarps were examined for the first time. Mericarps were rich in α-linolenic acid (47.72%), β-sitosterol (54.46%), γ-tocopherol (375.68 mg/kg), and potassium (75.4...

Chromosomal data are valuable and very useful for revealing evolution and speciation processes. Due to its wide distribution throughout the world, morphological differences, and chromosomal alterations, Erodium L’Hér. is an important genus for investigating the relationship between chromosomal alterations and karyotype evolution. In the present stu...

The taxa belonging to the genus Erodium L'Her., placed in the family Geraniaceae (Turnagagasıgiller), is known as "dönbaba" and "iğnelik" in Turkey. Erodium genus, represented by 26 species in our flora, has been reported to have different ethnobotanical uses in various countries against edema, liver disorders, constipation, tooth and stomach pain,...

The pollen grains of 19 Turkish Salvia species in Aethiopis, Drymosphace, Hemisphace, Hymenosphace and Salvia sections, 13 of which are endemic to Turkey, were investigated, documented and illustrated through Light Microscopy (LM) and Scanning Electron Microscopy (SEM). This study provides pollen data of 14 species for the first time. The pollen gr...

Leucojum aestivum (snowflake) contains galantamine, a medication used for the treatment of Alzheimer's disease. However, polyphenolic compounds of this species were not studied earlier. Proper understanding of the polyphenolics in the species and their antioxidant properties may lead to a review of their medical use. Therefore, in this study, the p...

Herbal medicine has been used worldwide as an alternative treatment. Salvia genus is one of the most remarked herbs which is traditionally used in the treatment of many diseases. Therefore, it is a crucial issue to reveal the chemical and biological profiles of different Salvia species. Rosmarinic and carnosic acid are the most well-known bioactive...

Diabetic patients suffer from persistent and non-healing wounds. Salvia species are traditionally used for the treatment of wounds and colds. The aims of the present study were to evaluate the in vivo wound healing potential, in vitro antimicrobial and antioxidant activities, and total phenolic and flavonoid contents of the aerial parts of two ende...

Several medicinal plants to treat diabetic wound healing were researched and are still under investigation. A variety of processes contributed to diabetics such as; inhibition of inflammatory response, generation of reactive oxygen species, differentiation of the extracellular matrix and reduced collagen production. The purpose of this study was to...

Purpose: Wound healing is slow and difficult in diabetic patients and effects quality of life. A variety of processes contributed to diabetics such as; inhibition of inflammatory response, generation of reactive oxygen species, differentiation of the extracellular matrix and reduced collagen production [1].Several medicinal plants to treat diabetic...

Lamiaceae familyası içindeki Nepetoideae alt familyasının Mentheae oymağına ait olan Salvia L. (adaçayı) cinsi tıbbi, süs bitkisi, gıda ve halüsinojenik kullanımları nedeniyle ile iyi bilinmektedir. Bu cinsin Hemisphace Benth. seksiyonu Türkiye’de üç tür ile temsil edilir. Bu güncel çalışma, ilgili seksiyona ait morfolojik olarak birbirine benzeyen...

This study examined the detailed chromosome measurements and karyotype asymmetries of seven taxa in the genus Vicia. The taxa are V. articulata, V. cassubica, V. villosa subsp. villosa in sect. Cracca, V. noeana var. noeana, V. sativa subsp. sativa, V. peregrina in sect. Vicia and V. caesarea in sect. Ervum. V. cassubica, V. noeana var. noeana, V....

The ethanol extracts obtained from the aerial parts of three Salvia species (S. hypargeia, S. huberi and S. dichroantha) which are endemic to Turkey were tested for their antibac-terial and antifungal activities against two Gram (+) bacterial strains [Staphylococcus aureus (ATCC 25925), Bacillus subtilis (ATCC 6633)]; three Gram (-) bacterial strai...

Lathyrus L. (Papilionoideae, Fabaceae), a cosmopolitan genus, has great significance in terms of food and agricultural areas. There are too few studies on the vegetative anatomy and the floral and foliar micromorphology of the genus. The present study is therefore carried out by means of multivariate cluster analysis (CA) and principal coordinate a...

Lathyrus L. (Papilionoideae, Fabaceae) is considered economically, ecologically, and genetically among the most significant genera of the flowering plants having its centre of diversity in Southwest Asia where Turkey is located. The anatomical and micromorphological characteristics of species of the genus Lathyrus have been reported in only a few s...

This study aims to carry out multivariate statistical analyses on 59 taxa of the genus Salvia L. (sage) naturally found in East and Southeast Anatolia in Turkey based on macromorphological, anatomical, palynological and mericarp micromorphological characteristics, to construct an infrageneric grouping in the genus and to understand the phylogenetic...

The main objectives of the current study are to perform multivariate analyses (e.g. cluster analysis and principle coordinate analysis) on 15 taxa belonging to the genus Lathyrus L. sect. Platystylis (=Lathyrostylis) in Turkey on the basis of macromorphological, anatomical and micromorphological properties, to elucidate the phylogenetic relationshi...

Aim of the study: The main objectives of the current study are to perform multivariate analyses (e.g. cluster analysis and principle coordinate analysis) on 15 taxa belonging to the genus Lathyrus L. sect. Platystylis (=Lathyrostylis) in Turkey on the basis of macromorphological, anatomical and micromorphological properties, to elucidate the phylog...

Inhibitory effect of Salvia species herbal preparations on acetylcholinesterase (AChE) and butylcholinesterase (BuChE) activitiy may contribute to regulation of cognitive performance and impaired cholinergic functions in patients with Alzheimer’s disease. This functional role of Salvia species and their components makes the investigations on Salvia...

To investigate the phylogenetic relationships of Salvia euphratica sensu lato and its closely related species with a focus on the section Hymenosphace, we screened five different regions; one nuclear ribosomal DNA region (Internal Transcribed Spacer, ITS) and four chloroplast DNA regions [trnT-trnL intergenic spacer (IGS), trnL in-tron, trnL-trnF I...

The genus Salvia is represented in Turkey by 95 species, of which 48 are endemic. Salvia ceratophylla L. was collected from Kayseri, Elazığ and Adıyaman in Turkey. The volatile components obtained from three samples by using microdistillation were analyzed by GC and GC/MS systems simultaneously. 30, 35 and 27 components of S. ceratophylla from Kays...

In this study, the karyotypes of mitotic chromosomes were determined of seven taxa of Salvia (Lamiaceae) collected from their natural habitats in Turkey: S. viridis (2n = 16), S. candidissima subsp. occidentalis (2n = 20), S. sclarea, S. ceratophylla, S. chionantha (2n = 22), S. viscosa and S. verticillata subsp. amasiaca (2n = 32). The karyotype f...

The pollen morphology of the ten taxa belonging to Cassubicae Radzhi, Cracca Dumort., Ervilia (Link) Koch, Lentopsis Kupicha, Trigonellopsis Rech. f. and Variegatae Radzhi sections of the genus Vicia L. subgenus Vicilla (Schur) Rouy (Fabeae, Fabaceae) in Turkey has been examined by use of light microscopy and scanning electron microscopy. Twelve mo...

The present paper reports the results of studies on the macromorphological, anatomical, seed-coat surface, petal and sepal epidermal micromorphological characteristics of L. nissolia L., the only one member of the genus Lathyrus L. sect. Nissolia (J.Mill.) Dumort (Fabaceae) using light and scanning electron microscopy. The amended and expanded macr...

Salvia quezelii is a very little known local endemic species from Turkey. Since 2005, our revisional studies on the genus in Turkey have been shown that previously known two localities of the species including type locality are wrong, and the species has not been col-lected since 1970. In this study, the type locality of the species is amended and...

In this study, the pollen morphology of 11 taxa belonging to Atossa (Alef.) Asch. & Graebner, Hypechusa (Alef.) Asch. & Graebner, Peregrinae Kupicha, Wiggersia (Alef.) Maxted, Vicia L. and Narbonensis (Radzhi) Maxted sections of the genus Vicia L. subgenus Vicia (Fabeae, Fabaceae) naturally growing in Turkey has been studied using Light Microscopy...

In this study, cholinesterase inhibitory potential relevant to Alzheimer's disease and antioxidant activities of the dichloromethane, ethyl acetate, and ethanol extracts from the aerial parts and/or roots of fourteen Salvia (sage) species (S. argentea, S. bracteata, S. caespitosa, S. cryptantha, S. glutinosa, S. indica, S. microstegia, S. multicaul...

Palynological characteristics of 30 Salvia taxa in sections Hymenosphace and Aethiopis from Turkey were investigated by light and scanning electron microscopy. S. aethiopis (sect. Aethiopis) has the smallest pollen while S. blepharochlaena (sect. Hymenosphace) has the largest pollen. The basic shape of the pollen grains in most taxa is suboblate, o...

Allium is one of the largest monocotyledonous genera. Southwest to Central Asia is the major center of diversity for the genus. In the present study, seeds of 62 Allium taxa from Turkey classified in subg. Allium (sect. Allium, sect. Brevispatha, sect. Codonoprasum and sect. Multicaule), subg. Amerallium (sect. Molium), subg. Melanocommyum (sect. A...

In this study, the epidermal types and their distribution on dorsal and lateral petals, the trichome types and their density on sepals of Lathyrus chloranthus, L. digitatus, L. laxiflorus subsp. laxiflorus, L. roseus subsp. roseus, L. sativus, and L. tuberosus, belonging to sections Lathyrus, Lathyrostylis, Pratensis, and Orobon of the genus Lathyr...

Abstract The pollen morphology of 21 taxa of the genus Lathyrus, representing 9 sections Orobus, Lathyrostylis (=Platystylis), Lathyrus (syn. Cicercula), Orobon, Pratensis, Aphaca, Viciopsis, Linearicarpus and Nissolia from Central Anatolia, Turkey was investigated using light microscopy (LM) and scanning electron microscopy (SEM). The pollen grai...

The current conservation status of the Salvia L. (sage) taxa of the family Lamiaceae distributed in the East, South-East, Central, North Anatolian, and Marmara geographic regions of Turkey was reassessed at regional, national, and global levels using IUCN Red List categories and criteria. In accordance with the present taxonomic revision of the gen...

Salvia siirtica Kahraman, Celep & Doğan sp. nov.(Lamiaceae) is described and illustrated as a new species from the northern part of Siirt province in southeast Anatolia, Turkey, where it was found growing in open forests of Quercus. It is morphologically similar to S. indica L., but differs by having densely glandular pilose to villous stems and pe...

In European folk medicine, Salvia species have traditionally been used to enhance memory. In our previous study of 55 Salvia taxa, we explored significant anticholinesterase activity of cultivated S. fruticosa. In this study, we compared the inhibitory activity of dichloromethane, ethyl acetate, and ethanol extracts of 3 wild-grown samples and 1 cu...

Salvia aucheri Benth. (Lamiaceae) is a species endemic to Turkey, and the name is lectotypified herein. Two varieties were previously recognized, as S. aucheri var. aucheri and S. aucheri var. canescens Boiss. & Heldr.; the infraspecific taxa are recognized here as subspecies. During revisionary work on Turkish Salvia L., we determined that S. auch...

Pollen grains of 30 taxa of the genus Salvia, belonging to sections Salvia, Horminum, Drymosphace, Plethiosphace and Hemisphace from Turkey were examined by light (LM) and scanning electron microscopy (SEM). Detailed pollen morphological characteristics are provided for these taxa. Among the studied taxa, S. verticillata subsp. verticillata from se...

Mericarp morphology of 15 taxa of Salvia L. section Hymenosphace Benth. in Turkey were investigated by light microscopy (LM) and scanning electron microscopy (SEM) to evaluate the utility of mericarp characters in systematic studies. Mericarps ranged from 2.50 to 5.38mm in length and 2.04 to 4.70mm in width. Mericarp shape was prolate-spheroid or n...

Background and aims - Turkey is one of the major centers of diversity for Salvia, with 97 species of which 54% are endemic. The aims of this study are to give detailed taxonomical, morphological and ecological accounts of S. cadmica and S. smyrnaea. Methods - Based on herbarium studies and field observations, numerical and morphological studies hav...

The taxa of the genus Salvia L. (Lamiaceae) used in this study were collected from their natural habitats in Turkey. In this paper, the number, size and morphology of somatic chromosomes of 22 Turkish taxa of Salvia, namely S. bracteata Banks & Sol., S. fruticosa Mill., S. huberi Hedge, S. hydrangea DC. ex Benth., S. nemorosa L. and S. pomifera L....

The anatomy, morphology and trichome distribution on the aerial parts of Lamium truncatum Boiss. were studied in order to understand the usefulness of these characteristics for systematic purposes. L. truncatum is a Mediterranean element which grows on shady hedge banks, glades, Quercus coccifera L. macchie and forest at an altitude of 300-1650 m i...

The morphology and anatomy of Lathyrus cilicicus Hayek & Siehe (Fabaceae) were studied in order to understand the usefulness of these characteristics for systematics purposes. Lathyrus cilicicus is a Mediterranena element which grows in macchie, cornfields and cliffs in the central portion of the Mediterranean region of Turkey. An expanded and amen...

As an initial part of a revisional study based on the genus Salvia L. (Lamiaceae), extensive fi eld studies, herbarium and literature surveys have been conducted on the basis of the S. brachyantha (Bordz.) Pobed and S. modesta Boiss. in order to understand their taxonomic status. As a result of the present study, S. brachyantha and S. modesta are a...