Ahmet Cem DuralIstinye Universitesi
Ahmet Cem Dural
Professor
Senior Consultant, Endocrine Surgery at LIV Hospital Ulus | Vadistanbul
About
146
Publications
82,416
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Introduction
General Surgery Specialist since 2009. Worked as surgeon between 2012-2021 in Bakirkoy Dr. Sadi Konuk Education & Research Hospital. Worked as research fellow in Cleveland Clinic, Dept. of Endocrine Surgery . Worked as fellow in Karolinska University Hospital, Department of Endocrine Surgery. Received European Board of Endocrine Surgery in 2015 and Associate Professor degree in 2017. Working at Istinye University since 2021, promoted to Full Clinical Professor degree in October 2022.
Additional affiliations
October 2021 - present
March 2017 - October 2021
November 2016 - July 2017
University of Ottawa, Faculty of Medicine, CHEO Research Institute II - Apoptosis Research Centre
Position
- Fellow
Education
October 2003 - October 2008
Istanbul University, School of Medicine
Field of study
- General Surgery Residency Program
September 1997 - August 2003
Istanbul University, School of Medicine
Field of study
- Medicine
Publications
Publications (146)
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which pati...
Aim:
In this study, we aimed to investigate the effects of Ultrasonic Coagulation (UC), Bipolar Energy Sealing System (BESS), Intra Operative Nerve Monitoring (IONM) and surgical experience on the complications of thyroid surgery.
Method:
The data of 1627 patients who underwent thyroid surgery for various indications in our department between 20...
To examine the effects of multidisciplinary approach and adjunct methods, on the surgical strategy, complications and treatment success of parathyroid surgery.
Patients, who were operated for primary hyperparathyroidism (n = 411) at our institution between 2012 and 2019 were reviewed retrospectively. Preoperative imaging studies, surgical method, a...
Adrenal schwannomas are rare benign tumors with no specific imaging and laboratory findings to diagnose preoperatively. Due to the limited number of cases in the literature, clinical, imaging, and pathological findings are presented in this study. Case 1 is a 61-year-old woman patient who has a 31-mm mass in the right adrenal gland. This mass was n...
Purpose
Although not as life-threatening as anastomotic leakage, anastomotic stricture reduces the quality of life. The risk factors for such an important life complication have not been revealed. This article examines the risk factors affecting anastomotic strictures due to colorectal cancers.
Methods
Patients who underwent anterior and low anter...
Pannexin 1 (PANX1) is expressed in many tissue types including tissues of neural origin. Neuroblastoma (NB) is a neural crest-derived malignancy mainly occurring in children. The majority of NB patients present with high-risk disease for which current therapies are ineffective. Here, we show that while PANX1 is expressed in NB of all stages, high P...
Objectives:
To evaluate our experience and short term surgical outcomes between two robotic systems.
Methods:
The present study retrospectively analyzed 38 cases, who underwent robotic adrenalectomy between 2012-2019 at our center. The patients were divided into Group Si (n=11) and Group Xi (n=27), and the results of these two groups were compar...
Background The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planning. This study aimed to develop and validate a novel index...
Objective:
To evaluate the effects of the pandemic process on those with an endocrinological disease that will require close follow-up from the last visit before the pandemic.
Materials and methods:
Patients of 3,903 with thyroid, calcium-bone metabolism, adrenal gland, pituitary diseases, and neuroendocrine tumor (NET) were retrospectively scan...
Background
Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and proces...
Background:
Conversion is a surgical concern because the surgical technique can change during surgery. Surprisingly, there is no study in the literature on the causes and risk factors leading to conversion in laparoscopic total extraperitoneal inguinal repair (TEP). There is also no consensus on the prevention and causes of this condition in TEP....
Doğal Acıklık Cerrahilerinin Tarihçesi İbrahim KARACA Doğal Acıklık Cerrahilerinde Anatomi Murat YASSA Doğal Acıklık Cerrahilerinde Kullanılan Aletler Raziye Kıcık ÇALIŞKAN Uterin Patolojilerde Doğal Acıklık Cerrahileri Cihan KAYA Aysun Fendal TUNCA Adneksiyel Patolojilerde Doğal Acıklık Cerrahileri İsmail ALAY İnfertilitede Doğal Acıklık Cerrahile...
Background:
Surgical treatment of Graves' disease (GD) has increased risk for bleeding, hypothyroidism and recurrent laryngeal nerve (RLN) palsy compared to other benign thyroidectomy indications. Nevertheless, it can be done safely in high volume centers. In some particular cases (i.e., anti-thyroid drug intolerance or thyrotoxicosis), urgent sur...
Objective: The aim of this study is to compare the intraoperative and short-term outcomes of different surgical approaches for hormone active and non-functional adrenal masses.
Methods: The data of 206 patients who underwent adrenal gland surgery in our clinic between 2012 and 2020 were retrospec- tively analyzed. Pre-operative outpatient clinic re...
SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism....
Purpose: Morbidity and mortality are higher in urgently operated abdominal hernia cases compared to elective surgeries. The present study aims to investigate the factors that cause increased morbidity and mortality in emergency surgical operations.
Methods: The files of a total of 426 patients who were operated for non-reducible abdominal hernia b...
Purpose: The aim of this paper is to investigate the effect of COVID-19 pandemic on general surgical emergencies as well as analyzing the effectiveness of measures taken in reducing the incidence of COVID-19 in patients and healthcare professionals.
Methods: Patients who underwent emergency surgery between the pandemic period of March 14th to May...
Purpose
Colonoscopic detorsion (CD) is the first treatment option for uncomplicated sigmoid volvulus (SV). We aim to examine the factors affecting the failure of CD.
Methods
The files of patients, treated after diagnosis of SV between January 2015 and September 2020, were retrospectively reviewed. Patients’ demographic data, comorbidities, endosco...
Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Su...
Objective
To evaluate the effects of the pandemic process on those with an
endocrinological disease that will require close follow-up from the last visitbefore the pandemic.
Design
This was a retrospective study.
Methods
Patients of 3903 with thyroid, calcium-bone metabolism, adrenal gland,
pituitary diseases, and neuroendocrine tumor (NET) were re...
Background/Aim: In recent years, laparoscopic repair has become common in the treatment of peptic ulcer perforation (PUP). In this study, we aimed to compare the advantages and disadvantages of laparoscopic and conventional graham omentopexy in the treatment of peptic ulcer perforation (PUP).
Methods: The files of the patients who underwent laparos...
Supplementary Data from the publication entitled: "SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study"
Background:
Parathyroid gland (PG) is an endocrine organ which may display different immunohistochemical stainings with chief cells and oxyphilic cells in normal as well as hyperplasic/tumoral lesions.
Purpose:
In this study, we aimed to identify the demographic properties and diagnostic value of the GATA3 antibody, which is a transcription fact...
Background
80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on...
p>Background: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications...
INTRODUCTION: Helicobacter pylori (H.pylori) has been shown to play a role in the development of chronic active gastritis, atrophic gastritis, gastrointestinal metaplasia, dysplasia, and gastric cancer, respectively. In our study, we aimed to evaluate the patients who underwent endoscopic examination in terms of endoscopic, pathological and laborat...
Background The COVID-19 pandemic caused by SARS-CoV-2 commenced in Wuhan China in 2019 and soon spread worldwide. SARS-CoV-2 enters the cell by binding to the ACE II receptor and begins viral replication. The effects and clinical findings of SARS-CoV-2 on the liver, kidney, heart, gastrointestinal (GI) system and especially lungs have been widely d...
Case report: Adrenal pseudocysts are rare bening lesions that usually mimick solid tumors on imaging. Although they are asymptomatic and often discovered incidentally, distinguishing them from clinically important adrenocortical masses may be problematic before surgery. We report the case of a 50-years-old female who was referred to endocrinology o...
Purpose
Novel thyroidectomy techniques have been described to minimize the visible scar. Hereby, we aim to present our experience with Trans Oral Robotic Thyroidectomy (TORT) without axillary access.
Material and Methods
Between August 2018 and March 2019, 6 eligible patients were enrolled to undergo TORT. Procedures were performed by using the Da...
Introduction: Thyroid surgery for benign and malign diseases is one of the most common procedures performed in surgical practice. Complication rates are higher in malignant and inflammatory diseases, recurrent surgeries and in hyperthyroid patients. Hypocalcemia is one of these complications. There are many studies investigating the effect of incid...
Background:
The COVID-19 pandemic caused by SARS-CoV-2 commenced in Wuhan China in 2019 and soon spread worldwide. It is a viral disease that involves many organs and progresses with high mortality. SARS-CoV-2 enters the cell by binding to the ACE II receptor and begins viral replication. A serious immune response occurs where it settles leading to...
Purpose: We aimed to investigate the effect of COVID-19 pandemic on general surgical emergencies. On the other hand, we analyzed the effectiveness of the measures we have taken and the incidence of COVID-19 of patients and healthcare professionals.
Method: In the pandemic period between March 14 and May 15, 2020, and in the same period of the previ...
Introduction: Aim of this study was to compare the results of laparoscopic adrenalectomy (LA) vs. robotic adrenalectomy (RA) performed in two referral endocrine surgery centers.
Method: Patients who underwent laparoscopic and robotic adrenalectomy between 2012 and 2019 were reviewed retrospectively. A 50 mm cut-off value for tumor diameter was use...
Aim: Parathyroid adenoma is the underlying etiology in 85% of patients with hyperparathyroidism. Parathyroid adenomas can be treated with focused parathyroid surgery, which is a minimally invasive method, if they can be localized in the preoperative period. In approximately 10% of cases, adenoma cannot be localized by the most commonly used imaging...
The 2019 novel coronavirus disease (COVID-19) was initially seen in Wuhan, China, in December 2019. World Health Organization
classified COVID-19 as a pandemic after its rapid spread worldwide in a few months. With the pandemic, all elective surgeries and
non-emergency procedures have been postponed in our country, as in others. Most of the endocri...
Objective: The aim of this observational clinical study was to evaluate the success of angiographic selective venous sampling (ASVS) in locating parathyroid adenoma in patients with primary hyperparathyroidism (PHPT), in whom the other imaging modalities have failed, and and to evaluate its possible contribution to the applicability of minimal inva...
COVID-19 pandemic is spreading rapidly in Turkey. We aimed to examine the numbers and demographic data of patients who applied to the general surgery outpatient clinics and operated in this process. Our primary outcome is to reveal the response of general surgery patients to the COVID-19 pandemic. The first COVID-19 case in Turkey has appeared in M...
Background: With increased utilization of robotic technology, robotic adrenalectomy (RA) becamepopular in certain high-volume centers as an alternative to conventional laparoscopic adrenalectomy (LA).The aim of the present study was to evaluate clinical and surgical outcomes of RA in two high-volume centers in Turkey.
Methods: Between 2012 and 2019...
Aim: A reticulin staining pattern (RSP) can be used for the differential diagnosis of endocrine gland lesions, as in the adrenal and hypophysis glands. We aimed to use RSP for the differential diagnosis of parathyroid gland lesions.
Materials and methods: In this study, we evaluated 97 parathyroid lesions in 85 patients, as well as 29 normal parath...
Vücut yüzeyinde oluşacak bir insizyon skarından kaçınmak amacı ile vücudun
ağız, üretra, vajina, anüs gibi doğal açıklıkları kullanılarak yapılan cerrahi
yöntemleri ‘Natural Orifice Transluminal Endoscopic Surgery’ (NOTES) olarak
tanımlanmıştır. Bu teknikte temel amaç hedef bölgeye minimal doku travması ile
ulaşarak, cilt insizyonu ile ilgili kompl...
ABSTRACT Despite the lower incidence of adrenal adenomas in general population, their frequency is increasing in the routine clinical practice due to improved accesibility of health benefits and development of radiologic imaging in last decade. Two questions should be answered primarily: Is the mass hormonally functional? Is it suspicious for malig...
Purpose
The use of nondepolarizing neuromuscular blocking agents (NMBAs) may affect intraoperative neuromonitoring (IONM) during anesthesia used during thyroid and parathyroid surgery.
Methods
The use of sugammadex was evaluated in a prospective clinical study during thyroid surgery. Between July 2018 and January 2019, 129 patients were prospective...
In this study, we aimed to evaluate the diagnostic value of thyroid imaging reporting and data system (TIRADS) in the estimation of malignancy and assess the concordance between TIRADS and the histopathology results of the postoperative specimens. Consecutive ultrasound imaging records of patients with multinodular goiter from January 2010 to Decem...
This presentation is about Transperitoneal laparoscopic adrenalectomy (TLA) and Posterior retroperitoneoscopic adrenalectomy (PRA) which are two popular approaches for minimally invasive adrenalectomy today. The presentation includes a brief description of two techniques with videos, pitfalls, advantages and disadvantages of these methods. An evide...
Aim: We aimed to compare the short-term results of patients who underwent laparoscopic (Group L) and robotic (Group R) transperitoneal adrenalectomy for adrenal masses.
Materials and Methods: The demographic characteristics, multidisciplinary endocrine council, radiology, operative and histopathology records of the patients operated between 2013-20...
Introduction: Since the first endoscopic intervention to the central neck for parathyroidectomy, numerous remote-access approaches have been described. The transoral approach offers several advantages as the shorter distance between oral vestibule requiring less dissection, access to both thyroid lobes and avoidance of any cutaneous scarring. As Tr...
Introduction: The laparoscopic adrenalectomy (LA) has become the gold standard since the transperitoneal laparoscopic approach was first reported.
Aim: To evaluate the applicability, safety and short-term results of laparoscopic surgery in adrenal masses over 6 cm.
Material and methods: Demographic data, hormonal activities, imaging modalities, ope...
Objectives: This study aims to compare the preoperative sonographic findings, fine-needle aspiration biopsy (FNAB) and postoperative histopathological results in patients who underwent total thyroidectomy. Patients and Methods: A total of 884 patients (199 males, 685 females; mean age 46.8±12.7 years; range, 16 to 82 years) who underwent total thyr...
İlk versiyonu 2014 yılında hazırlanmış olan bu kılavuz, iyi klinik uygulamalar kapsamında 2012 yılında kurulmuş olan Tiroid & Endokrin Cerrahisi branş poliklinik hizmetleri ve Multidisipliner Endokrin Konseyi tarafından hasta yönetiminin standardizasyonu amacıyla Sağlık Bilimleri Üniversitesi, Tıp Fakültesi, Bakırköy Dr. Sadi Konuk Eğitim ve Araştı...
Objectives: The purpose of this study was to calculate the long-axis-to-short axis ratio of breast masses pre-diagnosed as fibroadenoma (FA) on ultrasonography and determine its role in predicting malignancy.
Materials and Methods: Between January 2011 and March 2014, 1,154 patients who underwent tru-cut biopsy for the evaluation of solid breast m...
Objective: The aims of this study were firstly to evaluate the radiology and histopathology findings of patients diagnosed with intraductal lesions and who had undergone biopsies. The second objective was to investigate the surgery requirements in those cases diagnosed with intraductal papilloma (IDP) post operatively.
Material and Methods: Patient...
INTRODUCTION: Sacrococcygeal pilonidal disease is an infection and also chronic inflammation of the sacral region which has been generally seen in young patient population. Though, numerous surgical techniques have been described in the medical literature, a recent Cochrane review shows that the resection with an off-midline close technique should...
Adrenocortical cancer is seen rarily in the population but with a poor prognosis. The age distribution is bimodal and mostly seen in first and 5th decade. It may be associated with some hereditary cancer syndromes. In 60% of patients tumor can be functional and 35% of them it secretes more than one hormone. There is a distant metastasis in 30-40% o...
Objectives:This study aims to report the incidence of inadvertent parathyroid gland removal during thyroidectomies, as documented by pathology reports, and investigate its association with hypocalcemia.Materials and Methods:The patients who underwent thyroidectomy at our department between 2009 and 2013 were retrospectively reviewed. The patients w...
It is known that intestinal microbiota feeding habits in healthy humans have a direct effect on the formation of intestinal microbiota, while simultaneously playing the most important role in the development of the immune system. Our aim in this study was to investigate the effectiveness of this treatment method. Although there is no consensus on h...
Background: To evaluate the applicability, safety and short-term results of laparoscopic surgery in adrenal masses over six centimetres.
Methods: Demographic data, preoperative hormonal activities, imaging modalities, surgical and medical history, operative findings, operation time, conversion to open surgery, complications, duration of hospital st...
Aim: Fine needle aspiration biopsy (FNAB) is currently a widely accepted screening procedure in diagnosis of thyroid nodules, there has been confusion related to diagnostic terminology in the assessment of samples. This confusion has been caused by multiple category names, descriptive reports without assigning to a category, and different terminolo...
Introduction: Hypocalcaemia due to transient or definitive hypoparathyroidism is the most frequent complication after total thyroidectomy. We aimed to compare the impact of age on postoperative hypocalcemia and to determine which risk factors are important for hypocalcemia incidence.Methods: Eight hundred seventy-one patients, who underwent total t...
Adrenal neoplasms composed of more than one cell type and demonstrating a mixed histologic appearance are uncommon. A 57-year-old woman presented with history of nausea, increase in the frequency of urination, abdominal pain and hypertension. Laboratory workup revealed elevated urinary dopamine and metanephrine excretion in 24 hour urine collection...
Objective: We aimed to evaluate the outcomes of our multidisciplinary endocrine board (MEB) which is established for more specific treatment management of the patients with endocrine gland diseases.
Material and Methods: The MEB is established at 2012 in our institution. Prior to this date, the setup of board was a general tumor board (GTB) in whi...
Background and Objectives
Colonoscopy is the gold standard for detection of polyps and is preventive against colorectal cancers. Flat adenomas are small, superficial lesions and have a high rate of going undetected during conventional white-light endoscopy. This article adds to the scant body of literature in English regarding in vivo detection and...
Preoperative preparation of the hyperthyroid patient for thyroidectomy is imperative to avoid perioperative complications due to severe thyrotoxicosis. 24-years old woman was admitted at our clinic for uncontrolled Graves’ disease. In our case, agranulocytosis introduced by propylthiouracil. Therefore, surgery was the only chance of an effective th...
Objective: We aimed to determine the feasibility of TIRADS classification in differentiating benign from malignant thyroid nodules.
Methods: Consecutive ultrasound imaging records of patients with multinodular goiter from January 2010 and December 2015 who underwent surgery were retrospectively reviewed. The risk of malignancy of each TIRADS categ...
Objective: To investigate the impact of adrenal tumor board (ATB) in the management of adrenal gland diseases.
Methods and Materials: The data of patients with adrenal diseases evaluated in the ATB rounds between May 2013 and November 2016 were reviewed retrospectively in terms of demographics, diagnostic, laboratory, imaging, surgery and histopath...
Introduction: Indocyanine green dye with near-infrared fluorescent (ICG-NIRF) imaging has been used effectively to identify
tumoral tissue and its resection margins. This technique has been popularized for robotic surgery. We aimed to describe our initial experience with ICG-NIRF imaging during robotic right adrenalectomy in a patient with Cushing’...
Background
Liver resection is the treatment option with the best chance for cure in patients with malignant liver tumors. However, there are concerns regarding postoperative recovery in elderly patients, which may lead to a preference of non-resectional therapies over hepatectomy in this patient population. Although laparoscopic liver resection (LL...
The management of disappearing colorectal liver metastases in the postadjuvant chemotherapy setting is challenging. We describe a novel technique that facilitates laparoscopic resection of disappearing metastatic liver lesions with great precision. Details of this new technique are described in 2 patients with colorectal cancer synchronously metast...
Background
The introduction of robotic technology has revolutionized radical prostatectomy surgery. However, the potential benefits of robotic techniques may have trade-offs in increased mental demand for the surgeon and the physical demand for the assisting surgeon. This study employed an innovative motion tracking tool along with validated worklo...
Background and Objectives
Gastrointestinal cancers are the most frequently occurring cancers worldwide. Diagnosis and removal of polyps during screening endoscopy decreases the prevalence of colon cancer and cancer-related mortality, and it is considered to be the gold standard in gastrointestinal system cancer prevention. Technological innovations...