Ahmed K Ibrahim

• PhD
• Professor at Assiut University

Leprosy is a granulomatous disease affecting the skin, mucous membrane, and peripheral nerves. Irisin, a novel protein, has been associated with several inflammatory and metabolic diseases and has been demonstrated in peripheral nerve cells. The objective of this study was to compare the plasma irisin levels of newly diagnosed leprosy patients with...

Background: Post-stroke seizures (PSS), a common complication of cerebrovascular stroke (CVS), are classified into early post-stroke seizures (EPSS) and late post-stroke seizures (LPSS). Identifying the frequency, predictors, and health impact of PSS is crucial for optimal post-stroke management. Objective: To determine the risk factors, frequency,...

Background Post-stroke psychosis (PSP) is a rare but serious neuropsychiatric condition characterized by delusions and/or hallucinations following a stroke. Despite its impact on prognosis and quality of life, PSP remains underdiagnosed and undertreated, with limited data on its prevalence and risk factors. The purpose of this study is to assess th...

Psoriasis is a chronic, immune-mediated, hyperproliferative skin disease. Etiopathogenesis of psoriasis is not well understood. Plexin B2 was found to have effects on CD100-mediated T-cell morphology and expressed in the immune system. It may play a role in the pathogenesis of psoriasis. To assess the tissue level of plexin-B2 and plexin B2 related...

Background A biological indicator of cellular immunity is neopterin. In certain studies, psoriasis patients had higher serum, and urine neopterin levels, which were reduced following therapy. Aims To evaluate the effect of acitretin versus narrowband ultraviolet B (NB-UVB) and combinations of them on psoriasis vulgaris and correlate it with neopte...

Background Psoriasis is an autoimmune disease which has an effect on the joints and skin. Tumor Necrosis Factor‐Like Weak Inducer of Apoptosis (TWEAK) is a multi‐functional cytokine which regulates the cellular processes and has been related to a variation of conditions. Objectives To measure the level of serum TWEAK in psoriatic diseased persons...

Background A biological indicator of cellular immunity is neopterin. In certain studies, psoriasis patients had higher serum and urine neopterin levels, which reduced following therapy. Aims To evaluate effect of acitretin versus Narrowband UVB and combination of them on psoriasis vulgaris and correlate it with neopterin level. Patients and metho...

During the COVID-19 pandemic, major challenges are facing pediatric cancer centers regarding access to cancer centers, continuity of the anti-cancer therapy, hospital admission, and infection protection precautions. Pediatric oncologists actively treating children with cancer from 29 cancer centers at 11 countries were asked to answer a survey from...

Background Depression affects about 3.8% of the world’s population. Although marriage may contribute to subjective well-being, some marital variables could increase women’s risk for depression. This study aimed to determine the prevalence of depressive symptoms and their correlates among married females attending primary healthcare facilities. Met...

Background Medical students are at high risk of developing depressive symptoms rather than their age-matched group as medical education is stressful and medical students have psychological and academic stressors. The study aimed to estimate the prevalence of depressive symptoms and the most important correlates associated with it among Assiut Unive...

Background Internet addiction has been a topic of discussion in the academic literature for many years. As of April 2020, about 60 % of the world's population (nearly 4.6 billion people) were active internet user in their early adulthood. The prevalence among adolescent and college students ranged from 0.9 % to 33 %. The current study aimed to expl...

Background and aim Previous studies reported that iron-deficiency could be a risk factor for febrile seizure (FS), as the latter is more common in children younger than 2 years, and iron-deficiency anemia is also common in children of the same age. Yet, the relationship between iron deficiency and FS is not yet determined, and that is why this stud...

Introduction: Despite global efforts to contain the illness, COVID-19 continues to have severe health, life, and economic repercussions; thus, maintaining vaccine development is mandatory. Different directions concerning COVID-19 vaccines have emerged as a result of the vaccine's unpredictability. Aims: To study the determinants of the attitudes...

Background Cognitive impairment is an important aspect for stroke survivors. Little data are available about the frequency and risk factors of post-stroke dementia in Egypt. Objectives The aim of this study is to evaluate the frequency and predictors of post-stroke dementia and its impact on outcome. Methods A total of 380 patients with acute str...

Background: Fragility hip fracture is a common condition with serious consequences. Most outcomes data come from Western and Asian populations. There are few data from African and Middle Eastern countries. Objective: The primary objective was to describe mortality rates after fragility hip fracture in a Level-1 trauma centre in Egypt. The second...

Background: Melasma has significant emotional and psychological effects and significant negative impact on patients’ quality of life (QoL). Melasma QoL Scale (MELASQoL) is a specific questionnaire that has been developed to assess the effect of melasma on patient’s QoL. Objective: Translation, cultural adaptation, reliability and validation of mela...

BACKGROUND Succinylcholine is a preferred muscle relaxant for rapid sequence intubation. Postoperative myalgia (POM) is one of its commonest adverse effects with unknown pathogenesis. Various modalities were examined to reduce POM. We hypothesized that duloxetine may reduce incidence and severity of fasciculation or succinylcholine-induced POM in o...

Background: burnout syndrome is a serious and growing problem among medical staff. Its adverse outcomes not only affect health-care providers' health, but also extend to their patients, resulting in bad-quality care. The COVID-19 pandemic puts frontline health-care providers at greater risk of psychological stress and burnout syndrome. Objectives...

Abstract: Background: Fetuses, infants and children seem to be the most susceptible to the harmful effects of Environmental Tobacco Smoke (ETS). Significant maternal and fetal exposure to ETS inside the home may affect fetal health. The aim of the study was to evaluate the toxic effects of perinatal exposure to Second-Hand Smoke (SHS) on the infan...

Introduction Percutaneous coronary intervention (PCI) has improved recanalization of infarct-related arteries (IRA); however, TIMI-III flow does not always mean an efficient myocardial reperfusion. Myocardial blush grade (MBG) is used as a predictor for coronary microvascular obstruction. We assessed the association between ankle-brachial index (AB...

Rheumatoid arthritis (RA) is one of the most widespread autoimmune disorders and it has a genetic background with a variety of genes affecting the degradation of the immune system. Along these lines, we assessed the relationship between the BsmI, and FokI VDR polymorphisms and inflammable records identified with infections activity. Such as interle...

Background: Heart failure is the most common cause of hospitalization in elderly patients. It is likely that many of the mechanisms that contribute to reductions in systolic and diastolic function, seen in diabetic patients, place them at an increased risk of heart failure. Diuretic therapy, especially loop diuretics, is the usual way of managing c...

Background: Heart failure is the most common cause of hospitalization in elderly patients. It is likely that many of the mechanisms that contribute to reductions in systolic and diastolic function seen in diabetic patients also place them at an increased risk of heart failure. Diuretic therapy, especially loop diuretics, is the usual way of managin...

Background: Planar-based measurements of lesions in metastatic melanoma have limitations in estimating tumor burden of a patient and in predicting response to treatment. Volumetric imaging might add predictive value to Response criteria in Solid Tumor (RECIST)-measurement. Based on clinical observations, we explored the association between baselin...

Background: For children with cleft palates, surgeries at a young age are necessary to reduce feeding or phonation difficulties and reduce complications, especially respiratory tract infections and frequent sinusitis. We hypothesized that dexmedetomidine might prolong the postoperative analgesic duration when added to bupivacaine during nerve bloc...

Background Stroke is a medical emergency and considered the 2nd leading cause of mortality worldwide. High morbidity and mortality of stroke are due to some complications like cerebral edema, infection, and associated heart disease. Stroke may cause stress hyperglycemia and electrolyte disturbance that may be independent predictors for increased mo...

Background and aim Diabetic retinopathy is a serious and common complication of diabetes that causes irreversible blindness. The aim of the present study was to assess the knowledge, attitudes, and practice regarding diabetic retinopathy among patients attending a diabetic clinic and identify the effect of an educational program about diabetic reti...

Abstract Background and aim: Diabetic retinopathy is a serious and common complication of diabetes that cause irreversible blindness. The aim of the present study was to assess the knowledge, attitudes and practice of diabetic retinopathy among patients attending a diabetic clinic and identify the effect of an educational program about diabetic ret...

Introduction Acne scarring is a common undesirable complication of acne vulgaris. Fractional erbium-yttrium aluminum garnet (YAG) 2940 nm laser and platelet-rich plasma have been used in treating acne scars with variable outcomes. The objective of this study is to assess the efficacy of fractional erbium-YAG 2940 nm laser and platelet-rich plasma a...

Background: Various adjuvants were added to intrathecal anesthetics to improve quality of the block and postoperative analgesia. We hypothesized that intrathecal dexmedetomidine and magnesium sulfate (MgSO4 ) may add similar effects. Our objectives were to compare their effects as adjuvants to intrathecal bupivacaine on postoperative analgesia, st...

Introduction: Erectile dysfunction is a common condition among diabetic men. Many treatments are now available with variable responses. Aim: This study aimed to evaluate the effect of daily oral L-arginine plus tadalafil in diabetic patients with mild to moderate erectile dysfunction. Methods: A double-blinded, randomized, controlled clinical trial...

Introduction: Erectile dysfunction is a common condition among diabetic men. Many treatments are now available with variable responses. Aim: This study aimed to evaluate the effect of daily oral l-arginine plus tadalafil in diabetic patients with mild to moderate erectile dysfunction. Methods: A double-blinded, randomized, controlled clinical...

Abstract Background: Early awareness of pregnant women about neonatal jaundice (NNJ) has an essential role in preventing severe hyperbilirubinemia and its dangerous complications. Aim: the study aimed to assess the level of knowledge and attitude of pregnant women regarding NNJ and to evaluate the effect of an educational program for neonatal jaund...

Background and aim: Varicocele is one of the most common causes of male infertility. Leptin that has a role in sperm motility may have a role of varicocele. We aimed to study the effect of varicocelectomy on the serum and seminal leptin in patients with asthenozoospermia and the correlation between leptin levels, sperm parameters and varicocele gr...

Phone: +201092991101 Seminal and Serum Leptin levels in Male Patients with Varicocele and isolated Asthenozoospermia before and after Repair. ABSTRACT Background and Aim: Varicocele is one of the most common causes of male infertility.

CITATIONS 0 READS 132 5 authors, including: Some of the authors of this publication are also working on these related projects: galactin-3 and brain natriuretic peptide versus echocardiography in the early detection of cirrhotic cardiomyopathy View project Abstract Background: Early awareness of pregnant women about neonatal jaundice (NNJ) has an e...

Microorganisms, organic matter, heavy metals are the main pollutants in sewage water. The increasing water demand pressurized people to use the sewage water. Different systems, chemicals and physical treatments were used in sewage water treatment. The aim of this work is to study the effect and correlations of primary (Ca(OH)2 filtration and H2O2)...

Abstract: Vitamin D deficiency has been recognized as a worldwide epidemic, affecting even healthy population. The awareness and practices of primary health care physicians regarding vitamin D needs to be highlighted, as improving the knowledge of physicians will improve the knowledge of the public as a whole. This study aimed to address the knowle...

Abstract: Background: Saudi Health Information Survey reported that diabetes affects 13.2% of the population while 16.3% are borderline, also obesity affects 28.7% of the population. Diabetes has a major impact on health and quality of life. whereas, early control of type 2 diabetes also reduces the risk of mortality. Aim: we aimed to explore the p...

Introduction The association between anticardiolipin antibodies (aCL) and cardiac disease in the presence of systemic lupus erythematosus (SLE) has been reported in various clinical trials. However, the correlation between these auto-antibodies and right ventricular (RV) function has been inadequately investigated. Objective The present study inve...

Background: The new modified Melasma Area and Severity Index (mMASI) score, the recently used outcome measure for melasma, has not been tested to determine its sensitivity to change in melasma. Objective: To determine the reliability, validity, and sensitivity to change overtime of the mMASI score in assessment of the severity of melasma. Metho...

Background: Psoriasis has a significant negative impact on patients’ quality of life. Psoriasis Disability Index (PDI) is a psoriasis-specific questionnaire that was developed by Finlay and Coles, which concerns the functional lifestyle disabilities caused by psoriasis. It has been used internationally for almost 20 years and has been translated in...

Background/aims: Cirrhotic cardiomyopathy (CCM) is defined as an abnormal heart structure and function in cirrhotic patients. CCM includes systolic and diastolic dysfunction, electrophysiological abnormalities, and structural changes, both microscopic and macroscopic. Currently, there is no one diagnostic test that can identify patients with CCM....

Context: Striae distensae are linear atrophic dermal scars covered with flat atrophic epidermis. They may cause disfigurement, especially in females. Many factors may cause striae distensae such as steroids, obesity, and pregnancy. Although there is no standard treatment for striae; many topical applications, peeling, and light and laser systems h...

Background Low vitamin D status has been associated with vitiligo. Narrowband ultraviolet B (NB-UVB) therapy has improved vitamin D balance in psoriasis and atopic dermatitis; however, few data are available on such effect in vitiligo and the relationship of vitamin D levels with disease severity and repigmentation. Objective To investigate the inf...

Worldwide, the incidence of skin cancer has increased due to increased UV exposure to solar and artificial sources. In Saudi Arabia, skin cancer ranked the 9th most common cancer for both sexes. However, it is considered to be a preventable disease. WHO has proposed several preventive methods to avoid the damaging effects of excessive exposure to U...

Background: Osteoporosis is a global public health problem currently affecting millions of people worldwide, and Saudi Arabia is not an exception. Awareness and perceptions of susceptibility and belief in the seriousness of a disease can help in its prevention and control. We aimed to assess knowledge, attitude, and practices for osteoporosis amon...

Background: Pancreatic adenocarcinoma (PAC) is one of the most fatal human malignancies and complete surgical resection is the only treatment that offers a hope for prolonged survival. However, even after curative resection, the overall 5-year survival rate is only 10%-29%. Aim: we aimed to examine the preoperative and operative predictors for surv...

Vitamin deficiency is considered to be a major public health problem in Saudi Arabia, especially during summer. The major source of vitamin D is sun exposure. In this study, we aimed to determine the optimum time for sun exposure in four different cities (North, South, West and East regions) in the Kingdom of Saudi Arabia. In the current study ampo...

Aim of work: Idiopathic pulmonary fibrosis (IPF) is the second most common cause of admission to Chest Department at Assiut University hospital, the pattern of presentation, method for diagnosis and Co-morbidities need further studies. Aim: To explore demographic data and pattern of presentation of patients with IPF in upper Egypt and to study the...

Breast cancer is the first cancer among females in the Kingdom of Saudi Arabia, accounting for 27.4% of all newly diagnosed female cancers in 2010. There are several risk factors affecting the incidence of breast cancer where some factors influence the risk more than the others. We aimed to identify the different risk factors related to breast canc...

Background: Breast cancer has been ranked as the 1st cancer in women in Kingdom of Saudi Arabia. Screening, early detection and proper treatment of Breast Cancer was associated with more chances of better prognosis and long-term survival. The role general practitioner’s role is to provide professional knowledge, skills and support for patients as w...

Background: It is generally believed that osteoporosis is the most common metabolic disease affecting bone worldwide and the Kingdom of Saudi Arabia is not an exception. Awareness among physicians is essential for early detection and timely treatment and hence fractures prevention. Aim: We aimed to assess knowledge, attitude and practices for osteo...

Atopic dermatitis (AD) is a chronic inflammatory skin disorder with an immunologic basis. It may have negative medical and social impacts on a patient and his family. To assess serum level of vitamin D among children with AD and determine its association with AD severity using the AD Scoring System Index. A case-control study. Twenty-nine patients...

Surgery remains the mainstay of therapy for pancreatic head (PH) and periampullary carcinoma (PC) and provides the only chance of cure. Improvements of surgical technique, increased surgical experience and advances in anesthesia, intensive care and parenteral nutrition have substantially decreased surgical complications and increased survival. We e...

Background: Pancreatic adenocarcinoma is considered to be one of the most fatal human malignancies, Complete surgical resection is the only treatment that can offer hope for prolonged survival. However, even after a curative resection, the overall 5-year survival rate is only 10% to 29%. This bad prognosis is principally due to late diagnosis at an...

Background Varicocele is the most common cause of male infertility. Varicocele affects spermatogenesis negatively by increasing the levels of reactive oxygen species. Varicocelectomy may improve spermatogenesis and semen parameters. Aim To detect the efficacy of microsurgical varicocelectomy in decreasing seminal oxidative stress and improving sper...

Background Many university students experience some symptoms of depression during the course of their studies but there is evidence that students from less advantaged backgrounds may be more vulnerable. Methods The study was a cross-sectional online survey of 923 undergraduate students attending 6 UK Universities in the academic year 2009–2010 who...

Background: Depression is a common health problem, ranking third after cardiac and respiratory diseases as a major cause of disability. There is evidence to suggest that university students are at higher risk of depression, despite being a socially advantaged population, but the reported rates have shown wide variability across settings. Purpose:...

The Zagazig Depression Scale has been validated in Egyptian populations and the shortened form (ZDS-SF) found high rates of depression in Egyptian students. Preliminary research has supported the validity and reliability of the measure in a UK student but further work is needed. The study aimed to determine the criterion validity of the ZDS-SF agai...

There is some evidence that university students are at higher risk of depression; but rates have been found to vary widely across different countries, and there have been few surveys in representative samples. This study was carried out to assess the reliability of the Arabic-language Zagazig Depression Scale (ZDS) in a sample of Egyptian universit...

Worldwide population surveys show that prevalence of mental disorders in developing countries was as common as in industrialized countries. College life is an important stage in every person's life; unfortunately, it may be the time to experience depression for the first time. Latterly, there has been a steady increase in the number of university s...

It is thought that depressive disorders will be the second leading cause of disability worldwide by 2020. Recently, there is a steady increase in the number of university students diagnosed and treated as depression patients. It can be assumed that depression is a serious mental health problem for university students because it affects all age grou...