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Publications
Publications (16)
Aims: To evaluate the accuracy of a continuous intracoronary (IC) adenosine infusion, administered through a novel HYPEREM™IC over-the-wire microcatheter, to measure fractional flow reserve (FFR).
Methods and Results: The HYPEREMIC trial was a randomised, non-inferiority, crossover
study in which patients with intermediate coronary lesions were en...
Background:
The ischemic consequences of coronary artery stenosis can be assessed by invasive fractional flow reserve (FFR) or by noninvasive imaging. We sought to determine (1) the concordance between wall thickening assessment during clinically indicated stress echocardiography (SE) and FFR measurements and (2) the factors associated with hard e...
Introduction
The ischaemic consequences of a coronary artery stenosis can be assessed by invasive fractional flow reserve (FFR) or by non-invasive imaging. We sought to determine (i) the concordance between wall thickening assessment and FFR during clinically indicated stress echocardiography (SE) and FFR measurements and (ii) the predictors of har...
Introduction Haemodynamically significant coronary artery disease (CAD) is an important indication for revascularisation. Wall motion analysis during stress echocardiography (SE) is a noninvasive alternative to invasive fractional flow reserve (FFR) for evaluating hemodynamically significant CAD. We sought to determine the diagnostic accuracy of SE...
Objective:
Non-invasive cardiac imaging may suffer from poor image quality in morbidly obese individuals. This study aimed to determine the clinical value of contemporary stress echocardiography (SE) in morbidly obese patients referred for assessment of suspected coronary artery disease (CAD).
Methods:
This prospective, multicentre observational...
A 71-year-old woman presented with a 2-month history of intermittent solid dysphagia and weight loss of 7 kg. She reported no difficulty with swallowing liquids and also denied any anorexia, vomiting, nausea or change in voice. In addition, she had no change in bowel habit, jaundice or pale stools. Her medical history included paroxysmal atrial fib...
Background Significant obesity is an increasing global health problem. Obese individuals often have a clustering of cardiovascular risk factors such as hypertension, diabetes and dyslipidaemia. Thus, symptomatic patients often have a high pre-test probability of coronary artery disease (CAD) and are frequently referred for cardiac stress testing. T...
