Ahmed Abduljalal Abduljabbar

• PhD. student of Clinical Biochemistry
• Researcher at Erbil polytechnic university

Gentamicin (GM), which is in the aminoglycoside antibiotic class, is frequently preferred today in the treatment of diseases caused by gram-negative bacteria. However, its significant side effects on liver and kidney functions limit its clinical usefulness. The antioxidant and anti-inflammatory medical activities of eucalyptol (EUC, 1.8-cineole) ha...

Nutraceuticals are major contributors to human health because of their modulatory effects on various physiological and pathological processes. Arum rupicola (Kardeh) is a traditional medicinal food used for many gastrointestinal and enzymatic disorders. The present study evaluates the acute toxicity and hepatoprotective effects of methanolic extrac...

Ephedra intermedia has been used as a traditional therapy for various health purposes including gastric disorders. To validate its traditional use, we investigated the acute toxicity and the gastro-protective effects of E. intermedia leaf extract (EILE) in ethanol-induced gastric injury in rats. Sprague Dawley rats were randomly separated into 5 gr...

Background Dorema aucheri gum (DAG) is a bitter flavonoid gum widely used for numerous medicinal purposes including wound recovery. The present work investigates the acute toxicity and wound‐healing effects of DAG in excisional skin injury in rats. Materials and methods Sprague Dawley rats (24) were clustered into four groups, each rat had a full‐...

Corosolic acid (CA) is a well-known natural pentacyclic triterpene found in numerous therapeutic plants that can exhibit many bioactivities including anti-inflammatory and anti-tumor actions. The current investigation explores the chemoprotective roles of CA against azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) in rats. Thirty Spragu...

Cisplatin (CP) is a platinum-based anticancer drug used to treat many different solid tumors. Although CP has strong anticancer properties, its clinical use is limited due to side effects such as ototoxicity, neurotoxicity, myelosuppression and nephrotoxicity. Taxifolin (Tax) is reported to exhibit various possess effects such as antiinflammatory,...

Clinopodium menthifolium (wood calamint) is a folkloric medicinal plant ingested as a treatment for many human disorders including gastric disorders. Our study evaluates the anti-ulcer potentials of Clinopodium menthifolium ethanol extracts (CMEE) in induced gastric ulcers in rats. Thirty Dawley male rats were divided into 5 groups: normal and ulce...

Background: Hypericum perforatum (MEHP) is a broadly used therapeutic plant exhibiting numerous bioactivities. The present study evaluates acute toxicity and hepatoprotective effects of MEHP against thioacetamide (TAA)-induced liver injury in rats. Methods: The toxicity trial included a single oral administration of 2000 and 5000 mg/kg to rats. In...

Wound healing is a complex, intricate, and dynamic process that requires effective therapeutic management. The current study evaluates the wound healing potentials of methanolic extract of Cuminum cyminum L. seeds (CCS) in rats. Sprague Dawley (24) rats were distributed into four cages, wounds produced on the back of the neck, and received two dail...

Mangiferin (MF) is a natural C-glucosylxantone compound that has many substantial curative potentials against numerous illnesses including cancers. The present study's goal is to appraise the chemo preventive possessions of MF on azoxymethane (AOM)-mediated colonic aberrant crypt foci (ACF) in rats. Rats clustered into 5 groups, negative control (A...

The ketogenic diet (KD) is recognized as minimum carbohydrate and maximum fat intakes, which leads to ketosis stimulation, a state that is thought to metabolize fat more than carbohydrates for energy supply. KD has gained more interest in recent years and is for many purposes, including weight loss and managing serious diseases like type 2 diabetes...

Herbal medicine is one of the most common fields explored for combating colon cancers, and Pimpinella anisum L. seeds (PAS) have been utilized widely as medicinal agents because of their increased essential oil (trans-anethole) contents. In this essence, our study investigates the toxic effect and chemoprotective potentials of PAS against azoxymeth...

Objectives Pinostrobin (5-hydroxy-7-methoxyflavanone; PN) is a natural active ingredient with numerous biological activities extensively utilized in tumour chemotherapy. The present study investigates the chemo-preventive potentials of PN on azoxymethane-mediated colonic aberrant crypt foci in rats. Methods Sprague Dawley rats clustered into five...

Sinomenine (SN) is a well-documented unique plant alkaloid extracted from many herbal medicines. The present study evaluates the wound healing potentials of SN on dorsal neck injury in rats. A uniform cut was created on Sprague Dawley rats (24) which were arbitrarily aligned into 4 groups receiving two daily topical treatments for 14 days as follow...

Peptic ulcer disease is the greatest digestive disorder that has increased incidence and recurrence rates across all nations. Prangos pabularia (L.) has been well documented as a folkloric medicinal herb utilized for multiple disease conditions including gastric ulcers. Hence, the target study was investigation the gastro-protection effects of root...

Boric acid (BA) is a naturally occurring weak Lewis acid containing boron, oxygen, and hydrogen elements that can be found in water, soil, and plants. Because of its numerous biological potentials including anti-proliferation actions, the present investigates the chemopreventive possessions of BA on azoxymethane (AOM)-induced colonic aberrant crypt...

Background The Biarum species (Kardeh) has been consumed as a traditional functional food and medicine for decades. The current study investigates the phytochemistry, in-vitro and in-vivo bioactivities of methanol extracts of B. bovei. Methods The Gas-chromatography mass spectrophotometer (GS/GS-MS) was used to analyze the phytochemical profile of...

Many countries follow the recommendation of the World Health Organization by practicing physical gathering avoidance as one health measure to decrease COVID-19 the spread. The current study identifies the opinions and awareness of citizens about the commitments of workers (bakers, butchers, and food sellers) to health instructions and prevention. T...

Gynura procumbens is an edible flowering plant that has been utilized as traditional therapy for numerous diseases. The current experiment investigates the hepatoprotective potentials of the ethanol extract of Gynura procumbens leaf (EEGPL) against thioacetamide (TAA)-induced liver cirrhosis in rats. Thirty Sprague Dawley rats were randomly divided...

Sinapic acid (SA) is a natural pharmacological active compound found in berries, nuts, and cereals. The current study aimed to investigate the protective effects of SA against thioacetamide (TAA) fibrosis in rats by histopathological and immunohistochemical assays. The albino rats (30) were randomly divided into five groups (G). G1 was injected wit...

In an increasing interest in natural antiulcer compounds that may have gastric healing effects and possibly prevent ulcer recurrence, Polygonatum odoratum appears as a strong candidate. The gastroprotective potentials of P. odoratum rhizome extract (PORE) were explored on ethanol-induced gastric ulceration in rats. Sprague Dawley rats were caged in...

Onosma species (Boraginaceae) are well known as medicinal plants due to their wide range of pharmaceutical potential. The present study aims to investigate the anticancer (in vitro) and chemo-protective (in vivo) efficacies of Onosma mutabilis extract (OME) in the azoxymethane (AOM)-induced aberrant crypt foci (ACF) in rats. The in vitro antiprolif...

The genus Onosma belongs to the Boraginaceae family and contains over 230 species. The present review sheds light on the ethnopharmacology, phytoconstituents, bioactivity, and toxicology of the Onosma species from previous investigations. Furthermore, the paper also highlights the unresolved issues for the future investigations. The review included...

Pinostrobin was used in traditional medication for management of numerous syndromes. In the current study, histology, immunohistochemistry, and hepatoprotection effects of Pinostrobin were assessed against thioacetamide (TAA) hepatotoxicity in rats. Thirty rats were arbitrarily separated into five groups. Group 1 was intraperitoneally (i.p) injecte...

Pinostrobin was used in traditional medication for management of numerous syndromes. In the current study, histology, immunohistochemistry, and hepatoprotection effects of Pinostrobin were assessed against thioacetamide (TAA) hepatotoxicity in rats. Thirty rats were arbitrarily separated into five groups. Group 1 was intraperitoneally (i.p) injecte...

Pinostrobin was used in traditional medication for management of numerous syndromes. In the current study, histology, immunohistochemistry, and hepatoprotection effects of Pinostrobin were assessed against thioacetamide (TAA) hepatotoxicity in rats. Thirty rats were arbitrarily separated into five groups. Group 1 was intraperitoneally (i.p) injecte...

Tinospora crispa has been known as an herbal medicine with many biological activities. The current study evaluates silver nanoparticles in accelerating the rate of wound healing and closure of excision wounds in rats. A novel technique was followed to synthesize nanosilver particles, x-ray diffraction, UV–Vis's spectroscopy, and transition electron...

Papaver decaisnei (P. decaisnei) has been used as folkloric medicine for many health issues including gastric problems. The current study investigates the gastroprotective roles of P. decaisnei against ethanol-induced ulcers in rodents. Sprague Dawley rats (30) were separated into five groups: the normal group (G1) and the ulcer control group (G2)...

This research in vivo assessed the impact of the ethanolic extract of Annona muricata (A. muricata) on the histopathology, immunohistochemistry, and biochemistry of thioacetamide (TAA)-induced liver cirrhosis in Sprague Dawley rats. The rats, gavaged precisely with two doses of A. muricata (250 mg/kg and 500 mg/kg) with TAA, presented a substantial...

The medicinal plants (Astragalus species) have been used traditionally as anti-inflammatory, antioxidant, and Anti-diabetics. The current research investigates the phytochemistry and some biological activity of methanol extract of different parts of Astragalus bruguieri Bioss., a wild medicinal plant grows on Safeen mountain, Erbil, Iraq. The metha...

The prevalence of gastric ulcers has increased in recent years, mainly because of non-steroidal anti-inflammatory drug utilization. Therefore, the current study investigates the gastroprotective effect of p-Cymene on absolute ethanol-induced acute gastric mucosal hemorrhagic lesions in rats. Thirty Sprague Dawley rats were randomly separated into f...

e Papaver L. plant (Papaver decaisnei) has ethnobotanical records in many countries including Iraqi Kurdistan. e current study investigates the methanol (99.9%) extracts (10 μg/mL) of roots, leaves, and flowers of Papaver decaisnei in terms of phytochemistry by gas chromatography-mass spectrophotometry GC-MS, in vitro antioxidant activity by radica...

e Papaver L. plant (Papaver decaisnei) has ethnobotanical records in many countries including Iraqi Kurdistan. e current study investigates the methanol (99.9%) extracts (10 μg/mL) of roots, leaves, and flowers of Papaver decaisnei in terms of phytochemistry by gas chromatography-mass spectrophotometry GC-MS, in vitro antioxidant activity by radica...

The conducted research was done in Grda rasha field (Salahaddin University) for one month to compare the impacts of Alcea kurdica powder, Rifaxmine, and Ranitidine as anti-lesion and immune-strengthening agents on stress-induced quails which are affecting their growth rate and in severe cases causing gizzard erosion and deep intestinal lesions. To...

The conducted study compares the phytochemical and the antimicrobial potential of four varieties of Brassica napus seed oils. The plant seeds were cultivated during the winter growing season. Soxhlet extractor and Gas Chromatography-Mass Spectrometer (GC-MS) were used for essential oil analysis. The micro broth dilution assay was applied to test th...

The Papaver L. plant have been well known as a source of pharmaceutically valuable alkaloids (noscapine, thebaine, codeine, roemerine, papaverine and morphine). The current study investigates the phytochemical, in-vitro antioxidant, and anticancer activities of papaver decaisnei , an endemic plant species to the flora of Kurdistan-Iraq. The chemica...

Background: Diabetic Mellitus is an independent risk factor in patients with coronavirus disease 2019 (COVID-19), but data on the association of diabetes, acute kidney injury, and COVID-19 severityare limited to Middle East populations. Materials and Methods: This cohort study aimed to investigate these associations in 256 patients sequentially adm...

The traditional use of Onosma L. species as a remedy motivated scientists to discover great biological/pharmacological potentials in this plant. In the current study, in addition to the phytochemical composition of methanol (MeOH), water, and ethyl acetate extract of aerial parts of Onosma mutabilis Boiss., an endemic plant species in the flora of...

One of the preeminent factors of Coronary heart disease contemplated to be Hyperlipidemia. High cholesterol additives activates hyperlipidemia and Oxidative stress in rats eliciting biochemical and toxicological changes. Traditionally, Terminalia arjuna bark consumed as medicinal agents for various purposes, mainly as cardiac protectives. The prese...

The traditional use of Onosma L. species as a remedy motivated scientists to discover great biological/pharmacological potentials in this plant. In the current study, in addition to the phytochemical composition of methanol (MeOH), water, and ethyl acetate extract of aerial parts of Onosma mutabilis Boiss., an endemic plant species in the flora of...

The current work aims to study three seed cultivars of rapeseed (Brassica napus), as well as trying to provide a phytochemical insight of different rapeseed cultivars to be potentially cultivated as natural alternative hydrocarbon sources to petroleum hydrocarbons. The three seed cultivars, namely Heros, Sultan and Reandy were purchased from Britai...

The current work aims to study three seed cultivars of rapeseed (Brassica napus), as well as trying to provide a phytochemical insight of different rapeseed cultivars to be potentially cultivated as natural alternative hydrocarbon sources to petroleum hydrocarbons. The three seed cultivars, namely Heros, Sultan and Reandy were purchased from Britai...

The research project designed for the first time on comparison of Hybrirock seeds and pactol seeds of Brssica napus L. A plant affiliation of Brassicaceae family. The objective of this study was to phytochemically analyzing of France purchased Hybrirock and local pactol seeds by Gas chromatography mass spectrophotometry and comparison of their esse...

Gastroprotective role of Kurdish traditional wild plant

Homocysteine (Hcy) has been considered as an independent risk factor for coronary artery disease (CAD Oxidative stress and free radicals are known to have important roles in the development ofAngina Pectoris. Oxidative stress is present in cardiovascular diseases (CVDs), and hyperhomocysteinemia, an independent risk factor for these diseases, may p...

This study was conducted to investigate the potential of onion and garlic oils and their mixture supplementation under heat stress on the egg production, egg weight, total lipid concentration and antioxidant activity of local quail hens. Sixty birds at 42 weeks' age were evenly divided randomly into 4 treatments: feed in control (T0) free of onion...

The current study was conducted on 38 week old of local quails. The quails were divided into four groups, randomly allocated to four dietary treatments. The diet of the first group was supplemented with 2 ml/kg of onion oils, diet of the second group supplemented with 2 ml/kg of garlic oils, the third group was supplemented with a mix of (1 ml/kg o...

Thalassemia as a blood disorder has been known to passes down by parent to their offspring. The root of this disorder mainly returns to the Mediterranean Countries. Too much damage or degradation of erythrocytes is primarily the causative factor of the thalassemia as a result of producing defeated Hemoglobin Molecules, due to changes occurring in t...

Abstract: This experiment aimed at determination of vitamin D along with some Hematological parameters among women refugees from different camps and apparently healthy individuals in Hawler province; Kurdistan region of Iraq. 50 women refugees and 45 controls individual were studied between April and June, 2015. The results showed a lower level (p...