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Ahmed Abdel-Moneim

Ahmed Abdel-Moneim
Taif University and Beni Suef University · Virology

PhD, Virology

About

100
Publications
54,883
Reads
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1,602
Citations
Introduction
Ahmed Abdel-Moneim is a Professor of Virology in both Taif and Beni-Suef Universities.Prof. Abdel-Moneim researches are focused on the molecular characterization and genotyping of important viral pathogens in man and animals. Understanding of pathogens-host interaction is another research priority for Prof. Abdel-Moneim.
Additional affiliations
August 2009 - present
Taif University
Position
  • Principal Investigator
Description
  • Molecular evolution of human and animal viral diseases
August 2009 - present
Taif University
Position
  • Professor
August 2009 - present
Taif University
Position
  • Professor
Description
  • TEACHING VIROLOGY AND MICROBIOLOGY, COLLEGE OF MEDICINE, COLLEGE OF DENTISTRY
Education
September 1999 - February 2003
Cairo University
Field of study
  • Virology
September 1996 - March 1999
Cairo University
Field of study
  • Virology

Publications

Publications (100)
Article
Full-text available
Objective: To trace and understand the origin of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through various available literatures and accessible databases. Background: While the world enters the third year of the coronavirus disease 2019 pandemic and the health and socio-economic impacts continue to mount, the origin and mechan...
Article
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Newcastle disease (ND) is one of the most important poultry diseases worldwide and can lead to annual losses of up to 80% of backyard chickens in Africa. A retrospective cohort of 6 years was planned to screen the NDV in intensive chicken and turkey flocks. The existence of velogenic NDV strain was screened in different poultry flocks showing suspe...
Article
Full-text available
Like most of the RNA viruses, SARS-CoV-2 continuously mutates. Although many mutations have an insignificant impact on the virus properties, mutations in the surface protein, especially those in the receptor-binding domain, may lead to immune or vaccine escape variants, or altered binding activities to both the cell receptor and the drugs targeting...
Article
A multi‐country outbreak of the monkeypox virus has gained global attention. As of 25 May, 250 confirmed human monkeypox cases have been reported globally. Monkeypox is caused by the Monkeypox virus, which belongs to the Orthopoxvirus genus and Poxviridae family. Monkeypox is often a self‐limiting infection, with symptoms lasting 2 to 4 weeks with...
Article
Background Long haulers have been recently reported after contracting coronavirus disease (COVID-19). In the present study, we aimed to screen for the neuropsychiatric signs detected <1 to >6 months after infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to determine whether vaccination has an effect on them. Methods An...
Article
Full-text available
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic resulted in more than five hundred million infected cases worldwide. The current study aimed to screen the correlation of different laboratory findings with disease severity and clinical outcomes of coronavirus disease (COVID-19) among Egyptian patients to obtain prognostic i...
Article
Aim: This study aimed to measure the incidence of SARS-CoV-2 infection in neonates from infected mothers and to screen disease severity in neonates. Methods: We conducted a population-based cohort study of neonates from SARS-CoV-2-positive mothers, enrolling mothers who tested positive for SARS-CoV-2 and their neonates. Eleven infants <25 days o...
Article
The novel SARS-CoV-2 variant, Omicron (PANGO lineage B.1.1.529) is being reported from all around the world. The WHO has categorized Omicron as a Variant of Concern (VOC) considering its higher transmissibility and infectivity, vaccine breakthrough cases. As of 6 Jan 2022, Omicron has been reported in at least 149 countries. Therefore, this study w...
Article
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As the latest identified novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC), the influence of Omicron on our globe grows promptly. Compared with last VOC (Delta variant), more mutations were identified, which may address the characteristics of Omicron. Considering these crucial mutations and its implications...
Article
This communication summarizes the presentations given at the 1st international conference of the World Society for Virology (WSV) held virtually during 16–18 June 2021, under the theme of tackling global viral epidemics. The purpose of this biennial meeting is to foster international collaborations and address important viral epidemics in different...
Article
Full-text available
Infectious bronchitis virus GI-23 lineage, although described approximately two decades ago in the Middle East, has recently drawn remarkable attention and is considered an “emerging” lineage due to its current spread to several other regions, including Europe. Despite the relevance, no comprehensive studies are available investigating its epidemio...
Article
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The General Organization of the Veterinary Services in Egypt has adopted a sheeppox vaccination policy to control lumpy skin disease (LSD) in cattle. Over the course of the last two years, recurrent outbreaks were reported, with animals showing severe clinical signs and consequentially higher fatalities than that of cases reported in previous LSD o...
Article
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Background: Vaccination against SARS-CoV-2 is important for reducing hospitalization and mortalities. Both Pfizer-BioNTech (BNT162b2) and the Oxford-AstraZeneca (ChAdOx1 nCoV-19) vaccines are used in Saudi Arabia and in many parts of the world. Post-vaccinal side effects were recorded, so we aimed to screen different complaints after vaccination am...
Article
The levels of messenger RNA (mRNA) transcription of FOXP3, IFN-γ, TNF, IL-6 and COX-2 from both COVID-19 infected and control subjects were evaluated using SYBRTM green real-time polymerase chain reaction (RT-PCR). Severe/critical cases showed significantly lower lymphocyte counts and higher neutrophil counts than the mild or moderate cases. There...
Article
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Background: SARS-CoV-2, the causative agent of COVID-19, continues to cause a worldwide pandemic, with more than 147 million being affected globally as of this writing. People’s responses to COVID-19 range from asymptomatic to severe, and the disease is sometimes fatal. Its severity is affected by different factors and comorbidities of the infected...
Article
Full-text available
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to coronavirus disease 2019 (COVID-19) pandemic affecting nearly 71.2 million humans in more than 191 countries, with more than 1.6 million mortalities as of 12 December, 2020. The spike glycoprotein (S-protein), anchored onto the virus envelope, is the trimer of S-protein comprised o...
Article
SARS-CoV-2 is a novel coronavirus, spread among humans, and to date, more than 100 million of laboratory-confirmed cases have been reported worldwide. The virus demonstrates 96% similarity to a coronavirus from a horseshoe bat and most probably emerged from a spill over from bats or wild animal(s) to humans. Currently, two variants are circulating...
Article
Full-text available
SARS-CoV-2 is a newly emerged coronavirus that causes a respiratory disease with variable severity and fatal consequences. It was first reported in Wuhan and subsequently caused a global pandemic. The viral spike protein binds with the ACE-2 cell surface receptor for entry, while TMPRSS2 triggers its membrane fusion. In addition, RNA dependent RNA...
Article
Full-text available
Avian infectious bronchitis is a contagious viral disease, caused by avian infectious bronchitis virus (IBV), that leads to severe losses in the poultry industry all over the world. Since the 1950s, IBV has circulated in the Middle East and North Africa, and no tangible evidence has shown any effects of measures taken to control its spread or evolu...
Article
Full-text available
Lumpy skin disease (LSD) is an acute, sub-acute and chronic devastating disease of cattle. The current study was performed to determine various alterations in some haemato-biochemical parameters in calves naturally infected with lumpy skin disease virus (LSDV). Two groups of calves were enrolled in the study. The first group included nine Laborator...
Article
Full-text available
Middle East respiratory syndrome coronavirus (MERS‐CoV) is a Betacoronavirus that results in a severe fatal respiratory disease; however, it is also associated with mild inapparent infections. The western part of the Kingdom of Saudi Arabia (KSA) contains the holy places where millions of Muslims gathered from all over the world, all year round, wi...
Article
Background HSP70 is a significant cellular stress response protein that has intrinsic and extrinsic pathways to protect cells against apoptosis. It is one of the most induced proteins in cancer cells. The aim of the present study is to investigate the significant role of the HSP70 expression in Egyptian breast cancer (BC) patients and its potential...
Article
Full-text available
Despite the link between HCV and malignant lymphoproliferative disorders has been established, the association between occult hepatitis C virus infection and malignant lymphoproliferative disorders remains obscure. The present study intended to identify the possible association between occult HCV infection and malignant lymphoproliferative disorder...
Article
Full-text available
COVID-19 is the first known pandemic caused by a coronavirus, SARS-CoV-2, which is the third virus in the family Coronaviridae to cause fatal infections in humans after SARS-CoV and MERS-CoV. Animals are involved in the COVID-19 pandemic. This review summarizes the role of animals as reservoirs, natural hosts and experimental models. SARS-CoV-2 ori...
Article
Full-text available
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged early in December 2019 and currently affects most of the countries in all continents. As was very well highlighted by Correia, 1 there are a number of major scientific uncertainties underpinning the nature of SARS-CoV-2 that must be addressed; one of which is the degree to whi...
Article
Full-text available
Seasonal influenza viruses constitute a major global concern. Currently, H3N2 and H1N1pdm09 are the commonly circulating influenza A viruses. The haemagglutin and neuraminidase genes of influenza A(H3N2) and A(H1N1)pdm09 viruses from Egyptian paediatric patients with respiratory distress were sequenced. Mutational analysis of all published sequence...
Article
Full-text available
The World Society for Virology (WSV) was founded and incorporated as a nonprofit organization in the United States in 2017. WSV seeks to strengthen and support both virological research and virologists who conduct research of viruses that affect humans, other animals, plants, and other organisms. One of the objectives of WSV is to connect virologis...
Article
It is common practice to screen for human cytomegalovirus (CMV) and herpes simplex virus (HSV) among women with infertility problems, recurrent abortion or exhibiting intrauterine growth restriction during pregnancy. Nonetheless, limited information exists about the incidence of these viruses in Saudi Arabia. The IgG and IgM antibodies of 761 women...
Chapter
The viruses under the family Orthomyxoviridae are responsible for a variety of important respiratory diseases in humans and different animal species. The seven genera under the family are the influenza viruses A, B, C and D, Quaranjavirus, Thogotovirus and Isavirus. Viruses are highly evolving, and the genetic reassortment among viruses is seen onl...
Article
Full-text available
The applications of correct diagnostic approaches play a decisive role in timely containment of infectious diseases spread and mitigation of public health risks. Nevertheless, there is a need to update the diagnostics regularly to capture the new, emergent, and highly divergent viruses. Acute gastroenteritis of viral origin has been identified as a...
Article
Full-text available
HCV naturally infects both humans and chimpanzees. The high burden of the disease is related to the induction of chronic liver disease in 80% of infected humans with 20 % of the infected people develop liver cirrhosis and end‐ stage liver diseases as well as hepatocellular carcinoma (1). About half of the infected people did not show any noticeable...
Article
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Background and objectives: The human respiratory syncytial virus (hRSV) is among the important respiratory pathogens affecting children. Genotype-specific attachment (G) gene sequencing is usually used to determine the virus genotype. The reliability of the fusion (F) gene vs. G gene genotype-specific sequencing was screened. Materials and Methods:...
Article
Background: Peroxisome proliferator-activated receptors (PPARs) are transcription factors that belong to the superfamily of nuclear hormone receptors. Three PPARs members, PPAR-alpha, PPAR- delta and PPAR- gamma, have been characterized. PPAR-delta in humans is encoded by the PPARD gene and has been shown to possess a role in regulating fatty acid...
Article
Full-text available
Porcine astroviruses (PAstVs) have extended their distribution globally and have a high prevalence; however, their clinical significance is still under investigation. Thus far, information about their prevalence and diversity in the Indian pig population is unknown. This study is the first report on the prevalence and genetic characterization of PA...
Article
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[This corrects the article DOI: 10.1371/journal.pone.0193594.].
Article
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Human bocavirus is associated with respiratory disease worldwide, mainly in children. There are conflicting results, however, regarding the existence of the HBoV in blood donors. Three hundred whole blood samples from non-immunodeficient healthy blood donors were screened for the presence of HBoV by polymerase chain reaction. The HBoV genotype of p...
Data
Deduced nucleotide sequence of the VP1/NC of HBoV-1 from Saudi blood donors in comparison to different HBoV published strains. Strains related to the HBoV-1 genotype are boxed. Representative strains from HBoV-2, HBoV-3 and HBoV-4 are included. (PDF)
Article
Full-text available
Human respiratory syncytial virus causes severe lower respiratory tract infection in neonates and children. Genotype ON1, with duplication of 72-nt in the G gene, was first detected in Canada and then recorded in other countries. In the current study, we describe the first detection of the ON1 genotype among children in Egypt in 2014/2015. Sequence...
Article
Full-text available
Objective The current study was intended to evaluate the knowledge and awareness toward Middle East respiratory syndrome coronavirus (MERS-CoV) of pilgrims from Saudi Arabia and from different Arabian countries. Methods A prospective study was conducted among pilgrims from Saudi Arabia and those from other Arab nations. A total number of 2120 part...
Article
Full-text available
The World Health Organization Global Vaccine Action Plan aims to accelerate the control of preventable diseases, including seasonal influenza; however, seasonal influenza vaccination reluctance persists. The current study aimed to assess the knowledge and attitudes of Saudi nationals regarding seasonal influenza vaccinations. An anonymous questionn...
Article
The 2009 H1N1 pandemic (H1N1pdm09) was associated with a considerable influenza-related morbidity and mortality. Among the complications, Mycobacterial tuberculosis was recorded as a coinfection with influenza in rare cases. The full-length sequences of the viral haemagglutinin and neuraminidase of H1N1pdm09 influenza A virus were analyzed from a r...
Chapter
Full-text available
The abstract is published online only. If you did not include a short abstract for the online version when you submitted the manuscript, the first paragraph or the first 10 lines of the chapter will be displayed here. If possible, please provide us with an informative abstract. Avian infectious bronchitis virus is the prototype of the gammacoronavi...
Article
Full-text available
The human respiratory syncytial virus is a common respiratory pathogen in children. Improved diagnosis of the virus is dependent on the development of tools for the rapid detection and estimation of the viral loads. In this study RT-qPCR using TaqMan hydrolysis probe based on the F gene detection was developed to identify and quantify hRSV in clini...
Article
Full-text available
Purpose: Human bocavirus (HBoV) exsits in four genotypes: 1 to 4, with HBoV-1 being the most prevalent genotype. The aim of the current study was to genetically analyze the full-length genome of the HBoV-1 of recently detected Egyptian strains. Methodology: Seven overlapping sets of primers were developed to amplify an almost complete HBoV-1 gen...
Article
Full-text available
Highly pathogenic avian influenza subtype H5N1 represents a threat to the poultry industry and human health worldwide. Inapparently infected birds are suspected to play an essential role in the spread of avian influenza virus. In the current study, a total of 25,646 samples (16,185 chicken, 4696 ducks, 1633 geese and 3132 turkeys) from apparently h...
Article
Full-text available
Background: The emergence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae constitutes a serious problem because of the transfer of resistance genes from one organism to another. Objectives: To screen the antibiotic susceptibility of E. coli and K. pneumoniae from inpatients at King Abdul-Aziz Hospital, A...
Article
Full-text available
Human bocavirus (HBoV) is a prevalent virus worldwide and is mainly associated with respiratory disorders. Recently, it was detected in several disease conditions, including cancers. Colorectal cancer (CRC) is the third main cause of cancers worldwide. Risk factors that initiate cell transformation include nutritional, hereditary and infectious cau...
Article
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Group A rotavirus is responsible for inducing severe diarrhea in young children worldwide. Rotavirus vaccines are used to control the disease in many countries. In the current study, the sequences of human rotavirus G and P types in Saudi Arabia are reported and compared to different relevant published sequences. In addition, the VP4 and VP7 genes...
Article
Full-text available
In 2012 Middle-East respiratory syndrome coronavirus (MERS-CoV) was evolved in the Arabian Peninsula. Tremendous and successful efforts have been conducted to discover the genome structure, epidemiology, clinical signs, pathogenesis, diagnosis and antiviral therapy. Taphozous perforatus bats are the incriminated reservoir host and camels are the cu...
Article
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Human infection with H7 influenza subtypes usually resulted in mild disease with a rare mortalities, however, human infection with the avian low pathogenic H7N9 influenza virus resulted in about 38.6 % human fatality. Due to the new cross-species barrier of this virus subtype, there is an urgent need to better understand the susceptibility to comme...
Article
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Outside Asia, Egypt is considered to be an influenza H5N1 epicentre and presents a far greater pandemic risk than other countries. The long-term endemicity of H5N1 and the recent emergence of H9N2 in poultry call attention to the need for unravelling the epidemiology, ecology and highly diverse gene pool of influenza A virus (IAV) in Egypt which is...
Article
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Donkey domestication drastically changed ancient transport systems in Africa and Asia, enabling overland circulation of people and goods and influencing the organization of early cities and pastoral societies. Genetic studies based on mtDNA have pointed to the African wild ass as the most probable ancestor of the domestic donkey, but questions rega...