Ahmad Rizal Ganiem

Ahmad Rizal Ganiem
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Ahmad Rizal verified their affiliation via an institutional email.
Verified
Ahmad Rizal verified their affiliation via an institutional email.
  • MD, PhD
  • Neurology, Neuroinfection at Padjadjaran University

About

128
Publications
37,531
Reads
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1,838
Citations
Introduction
A lecturer in neurology, a researcher on the field of neuroinfection
Current institution
Padjadjaran University
Current position
  • Neurology, Neuroinfection
Additional affiliations
Hasan Sadikin Hospital
Position
  • Head of Department
January 2013 - present
Padjadjaran University
Position
  • Subdivision of Neuro-infection
January 2007 - present
Hasan Sadikin Hospital
Position
  • adult meningitis
Education
December 2006 - April 2013
Radboud University
Field of study
  • Medical Sciences

Publications

Publications (128)
Article
Background: Immunopathology contributes to the high mortality of tuberculous meningitis, but the biological pathways involved are mostly unknown. We aimed to compare cerebrospinal fluid (CSF) and serum metabolomes of patients with tuberculous meningitis with that of controls without tuberculous meningitis, and assess the link between metabolite co...
Article
Full-text available
The objective of this study was to determine the effect of Virtual Reality using smart phone on pain reduction in primiparity women during labour process. Labor pain experienced in labour is affected by the processing of multiple physiological and psychosocial factors. Perceptions of labour pain intensity vary. Very occasionally women feel no pain...
Article
Background.: Damaging inflammation is thought to contribute to the high morbidity and mortality of tuberculous meningitis (TBM), but the link between inflammation and outcome remains unclear. Methods.: We performed prospective clinical and routine laboratory analyses of a cohort of adult patients with TBM in Indonesia. We also examined the LTA4H...
Article
Full-text available
High-dose intravenous (i.v.) rifampicin improved the outcome of tuberculous meningitis (TBM) in a previous study. Unfortunately, i.v. rifampicin is not available in many high-endemic settings. This study examined exposures to and safety of higher oral rifampicin doses compared with i.v. rifampicin. Thirty adult Indonesian TBM patients were randomis...
Article
Full-text available
Pediatric TB meningitis (TBM) is a highly-morbid, oft-fatal disease. Standard treatment includes isoniazid, rifampin, pyrazinamide, and ethambutol. Current rifampin dosing achieves low cerebrospinal fluid (CSF) concentrations, and CSF penetration of ethambutol is poor. In adult trials, higher-dose rifampin and/or a fluoroquinolone reduced mortality...
Article
Full-text available
Abstrak Emesis gravidarum adalah mual-muntah yang menimbulkan gangguan aktivitas sehari-hari, bahkan bisa membahayakan bagi ibu dan janin. Mual muntah dialami sekitar 50−90% wanita. Ada dua cara yang sering digunakan untuk menghilangkan rasa mual, yaitu secara farmakologis salah satunya dengan pemberian vitamin B6 dan non-farmakologis dengan akupun...
Article
Full-text available
Recent data suggest that intensified antimicrobial treatment may improve the outcome of tuberculous meningitis (TBM). Considering that drug exposure is the intermediate link between dose and effect, we examined the concentration-response relationship for rifampicin and moxifloxacin in TBM patients. In an open-label, phase 2 clinical trial performed...
Article
Full-text available
Background Cryptococcal meningitis (CM) is a severe AIDS-defining illness with 90-day case mortality as high as 70% in sub-Saharan Africa, despite treatment. It is the leading cause of death in HIV patients in Asia and Africa. No major advance has been made in the treatment of CM since the 1970s. The mainstays of induction therapy are amphotericin...
Article
Full-text available
Introduction Previous studies, mostly from Africa, have shown that serum cryptococcal antigenemia may precede the development of cryptococcal meningitis and early death among patients with advanced HIV infection. We examined cryptococcal antigenemia as a risk factor for HIV-associated mortality in Indonesia, which is experiencing a rapidly growing...
Article
Full-text available
HIV-associated subacute meningitis is mostly caused by tuberculosis or cryptococcosis, but often no etiology can be established. In the absence of CT or MRI of the brain, toxoplasmosis is generally not considered as part of the differential diagnosis. We performed cerebrospinal fluid real time PCR and serological testing for Toxoplasma gondii in ar...
Data
STROBE checklist for the manuscript: “Cerebral toxoplasmosis mimicking subacute meningitis in HIV-infected patients; a cohort study from Indonesia”. (DOC)
Article
Full-text available
Bacteriological confirmation of tuberculous (TB) meningitis is difficult. Culture is slow and microscopy has insufficient sensitivity. We evaluated real time PCR targeting insertion sequence IS6110 among 230 consecutive adult patients with subacute meningitis in a referral hospital in Indonesia. Cerebrospinal fluid (CSF) samples were examined using...
Article
Background: Intensified antibiotic treatment might improve the outcome of tuberculous meningitis. We assessed pharmacokinetics, safety, and survival benefit of several treatment regimens containing high-dose rifampicin and moxifloxacin in patients with tuberculous meningitis in a hospital setting. Methods: In an open-label, phase 2 trial with a...
Article
Indonesia has a concentrated but rapidly growing HIV epidemic. We examined the effect of HIV on causative organisms, clinical features and prognosis of adult meningitis. A prospective cohort study. All adult patients at a referral hospital who underwent cerebrospinal fluid examination for suspected meningitis were examined for HIV and included in a...

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