Ahmad Jezzini

Ahmad Jezzini
Washington University in St. Louis | WUSTL , Wash U · Department of Anatomy and Neurobiology

PhD

About

16
Publications
4,720
Reads
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1,134
Citations
Additional affiliations
February 2020 - present
Washington University in St. Louis
Position
  • Instructor
September 2015 - February 2020
Washington University in St. Louis
Position
  • Researcher
December 2010 - August 2015
Stony Brook University
Position
  • PostDoc Position
Education
January 2006 - December 2009
Università di Parma
Field of study
  • Neuroscience
November 2003 - September 2004
Claude Bernard University Lyon 1
Field of study
  • Neuroscience

Publications

Publications (16)
Article
Full-text available
Multiple lines of evidence link economic choices to the orbitofrontal cortex (OFC), but other brain regions may contribute to the computation and comparison of economic values. A particularly strong candidate is the basolateral amygdala (BLA). Amygdala lesions impair performance in reinforcer devaluation tasks, suggesting that BLA contributes to va...
Article
Full-text available
Most of the research on cortical processing of taste has focused on either the primary gustatory cortex (GC) or the orbitofrontal cortex (OFC). However, these are not the only areas involved in taste processing. Gustatory information can also reach another frontal region, the medial prefrontal cortex (mPFC), via direct projections from GC. mPFC has...
Article
Full-text available
In the last few years, the insula has been the focus of many brain-imaging studies, mostly devoted to clarify its role in emotions and social communication. Physiological data, however, on which one may ground these correlative findings are almost totally lacking. Here, we investigated the functional properties of the insular cortex in behaving mon...
Article
Full-text available
Evidence from a large number of brain imaging studies has shown that, in humans, the insula, and especially its anterior part, is involved in emotions and emotion recognition. Typically, however, these studies revealed that, besides the insula, a variety of other cortical and subcortical areas are also active. Brain imaging studies are correlative...
Article
Full-text available
Primates interact with the world by exploring visual objects; they seek opportunities to view novel objects even when these have no extrinsic reward value. How the brain controls this novelty seeking is unknown. Here we show that novelty seeking in monkeys is regulated by the zona incerta (ZI). As monkeys made eye movements to familiar objects to t...
Article
Humans and animals can be strongly motivated to seek information to resolve uncertainty about rewards and punishments. In particular, despite its clinical and societal relevance, very little is known about information seeking about punishments. We show that attitudes toward information about punishments and rewards are distinct and separable at bot...
Preprint
Full-text available
Primates interact with the world by exploring visual objects; they seek opportunities to view novel objects even when these have no extrinsic reward value. How the brain controls this novelty seeking is unknown. Here we show that novelty seeking in monkeys is regulated by the zona incerta (ZI). As monkeys made eye movements to familiar objects to t...
Article
The brain mechanism for controlling continuous behavior in dynamic contexts must mediate action selection and learning across many timescales, responding differentially to the level of environmental uncertainty and volatility. In this review, we argue that a part of the frontal cortex known as the anterior cingulate cortex (ACC) is particularly wel...
Article
Full-text available
Over the last two decades the insula has been described as the sensory “interoceptive cortex”. As a consequence, human brain imaging studies have been focusing on the role of insula in the sensory perception of emotions. However, evidence from neurophysiological studies on non-human primates have shown that the insula is involved in generating emot...
Conference Paper
Full-text available
Multi-electrode arrays contain an increasing number of electrodes. The manual selection of good quality signals among hundreds of electrodes becomes impracticable for experimental neuroscientists. This increases the need for an automated selection of electrodes containing good quality signals. To motivate the automated selection, three experimenter...
Article
Full-text available
Mirror neurons are a distinct class of neurons that discharge both during the execution of a motor act and during observation of the same or similar motor act performed by another individual. However, the extent to which mirror neurons coding a motor act with a specific goal (e.g., grasping) might also respond to the observation of a motor act havi...
Article
Full-text available
The insula of Reil is a wide cortical region (~ 160mm² in rhesus monkey) buried in the depth of the sylvian fissure with an incomplete opercularization in non-human primates that reaches a complete opercularization only in the human brain. Researchers attributed to the insula and adjoining perisylvian regions in both monkeys and humans a very wide...
Article
Full-text available
We recorded motor-evoked potentials (MEPs) to transcranial magnetic stimulation from the right opponens pollicis (OP) muscle while participants observed an experimenter operating two types of pliers: pliers opened by the extension of the fingers and closed by their flexion ("normal pliers") and pliers opened by the flexion of the fingers and closed...
Article
Full-text available
The capacity to use tools is a fundamental evolutionary achievement. Its essence stands in the capacity to transfer a proximal goal (grasp a tool) to a distal goal (e.g., grasp food). Where and how does this goal transfer occur? Here, we show that, in monkeys trained to use tools, cortical motor neurons, active during hand grasping, also become act...
Article
Full-text available
This paper reports on a novel type of silicon-based microprobes with linear, two and three dimensional (3D) distribution of their recording sites. The microprobes comprise either single shafts, combs with multiple shafts or 3D arrays combining two combs with 9, 36 or 72 recording sites, respectively. The electrical interconnection of the probes is...

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Projects

Projects (2)
Project
The project focuses on the neural basis of the emotions, investigating their behavioral, interoceptive and phenomenological aspects by means of electrical stimulation. The aim is to integrate correlative (e.g. fMRI and EEG) studies on emotion with those obtained by using electrical stimulation, i.e. a gold-standard technique for investigating the causal link between brain regions and their functions.
Project
The project focuses on the behavioral and neuroscientific investigation of emotions in humans and non-human primates. The starting assumption is that the classic experience/expression dichotomous account of emotions, according to which to experience and to express an emotion are two independent processes, should be abandoned. The project capitalize upon Dewey’ s and Mead’s account of emotions, according to which emotion expression is part of the emotional experience.