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Scanning electrochemical microscopy (SECM) is discussed as a versatile tool to provide a unique approach of localized electrochemical information in the context of biosensing research. The step‐by‐step immobilization of DNA aptamer with intrinsic redox activity on screen‐printed carbon electrode (SPCE) was successfully monitored using SECM imaging...
A label-free electrochemical aptasensor was fabricated for reagentless determination of tetracycline (TET) in water. A 5′-amino-modified 76-mer oligonucleotide was immobilized on screen-printed carbon electrode via carbodimide coupling. Cyclic voltammetry experiments revealed an unexpected electroactivity of immobilized aptamer, showing a quasi-rev...