Agustín Lara-Esqueda

• Consultant at AXMILAB

Pederin is a vesicant toxic amide, found in the hemolymph of the beetle genus, Paederus. Physical contact with these insects produces a type of irritant dermatitis with variable clinical symptoms. It has been identified that Pederin (a vesicant toxic amide responsible for the ulcerative lesion) is produced by Gram-negative endosymbiotic bacteria of...

Rheumatoid arthritis is globally present in about 1% of the population. This autoinflammatory disease modifies the connective tissue, causing pain and inflammation of the joints. Over time, it causes the loss of joint cartilage and bone mass, decreasing the patient's quality of life. Treatment options now available either give symptomatic alleviati...

Objective: Identify the effects of the National School Coexistence Program on mental health in parents of primary and secondary education students, applied in the 2020-2021 school year, a period characterized by confinement caused by COVID-19. Methodology: research carried out by an exploratory, non-experimental, observational and cross-sectional s...

Introduction: The present study evaluated the quality of medical care for patients diagnosed with diabetes mellitus (DM), hypertension (HBP), and both pathologies (DM+HBP) within a public health system in Mexico. Methods: 45,498 patients were included from 2012 to 2015. All information was taken from the electronic medical record database. Each...

Se hace revisión general de los antibióticos, antimicrobianos no antibióticos y antisépticos, las etapas en la cicatrización de las heridas y resultados clínicos con el uso de la fórmula Vikut como alternativa de antimicrobiano no antibiótico en la cicatrización de heridas agudas y crónicas

Inflammation is an essential component of prostate cancer (PCa), and mefenamic acid has been reported to decrease its biochemical progression. The current standard therapy for PCa is androgen deprivation therapy (ADT), which has side effects such as cognitive dysfunction, risk of Alzheimer's disease, and dementia. Published results of in vitro test...

Introduction: COVID-19 pandemic affects human health and the global economy. Its evolution is unpredictable, making it hard for governments to provide response actions suited for all populations. Meanwhile, informal street workers carry on with their labor despite contingency measures to sustain their lives. The objective was to conduct a case-con...

BACKGROUND Diabetes Mellitus is a worldwide health problem and the leading cause of premature death with increasing prevalence over time. Usually, along with it, Hypertension presents and acts as another risk factor that increases mortality risk. Both diseases impact the country's health while also producing an economic burden for society, causing...

The automobile (or car) is a symbol of the twentieth and twenty-first centuries that move its drivers from one place to another, but it can also bring about behavioral changes in them. Changes in sexual behavior resulting from having a car have not been quantified. Given that emerging adults belong to a vulnerable and psychologically immature group...

las heridas

Potassium permanganate has been reported to be an effective treatment for certain types of wounds. The aim of the present study was to evaluate the use of potassium permanganate in the treatment of diabetic foot ulcers. A single-blind, randomized, controlled clinical trial was conducted on patients with type 2 diabetes mellitus that presented with...

Summary Background: Breast cancer is a public health problem and it is the most common gynecologic neoplasia worldwide. The risk factors for its development are of both hereditary and environmental origin. Certain foods have been clearly associated with modifying the breast cancer risk. The aim of the present analysis was to evaluate the effects of...

Nonalcoholic steatohepatitis (NASH) is currently one of the primary liver diseases. Recent studies have shown a clinical relation between NASH and atherosclerosis. There is much interest in these two diseases because they are both associated with great morbidity and mortality. Inflammation and the overexpression of COX-2 participate in the pathophy...

Background: Breast cancer is a public health problem and it is the most common gynecologic neoplasia worldwide. The risk factors for its development are of both hereditary and environmental origin. Certain foods have been clearly associated with modifying the breast cancer risk. The aim of the present analysis was to evaluate the effects of cow's...

Ante las necesidades actuales nacionales e internacionales que de¬mandan la atención y las acciones inmediatas de disminuir los índices de las enfermedades crónico-degenerativas no transmisibles (ECNT), la Secretaría de Salud y Bienestar Social del Estado de Colima presenta una alternativa más en acciones con un enfoque innovador. La creación de u...

ABsTRAcT ARTIcLE InfO ______________________________________________________________ ______________________ Meclofenamic acid is a nonsteroidal anti-inflammatory drug that has shown therapeutic potential for different types of cancers, including androgen-independent prostate neo-plasms. The antitumor effect of diverse nonsteroidal anti-inflammatory...

Uterine cervical cancer (UCC) is one of the main causes of cancer‑associated mortality in women. Inflammation has been identified as an important component of this neoplasia; in this context, anti‑inflammatory drugs represent possible prophylactic and/or therapeutic alternatives that require further investigation. Anti‑inflammatory drugs are common...

Breast cancer is the most common gynecologic malignancy known worldwide. The consumption of certain foods may modify the risk for its development. Peanuts and other seeds have shown anticarcinogenic effects in vitro, but there are a few studies that evaluate the effect of their consumption on the development of breast cancer. The aim of the present...

Abstract: Recent studies have demonstrated a clinical relation between steatohepatitis and atherosclerosis. Both pathologies are of much interest due to the great morbidity and mortality associated with them and studies in animal models are necessary in order to find new therapies. The aim of the present study was to establish a new model for the s...

A high-fat diet and male obesity are aspects associated with germinal epithelial alterations and male infertility. Some reports have shown that certain tetracyclines can protect the germinal epithelium from toxic drugs. The aim of the present study design was to evaluate the possible effect of doxycycline on testicular germ cells in individuals fed...

Dengue is a mosquito-borne infection that causes a mild to moderate disease and, occasionally, a potentially lethal complication called dengue hemorrhagic fever or dengue hemorrhagic fever (DHF / DHF / dengue severe). In recent decades it has become an international public health problem, by its most severe (DH / DHF). The high incidence in 2009 pr...

La Diabetes Mellitus pertene-ce al abanico de enfermeda-des crónico-degenerativas que aqueja a la población geriátrica creciente. Las caídas en adul-tos mayores con Diabetes Melli-tus son una porción importante del problema de salud pública que representan las caídas, su mortalidad y morbilidades sub-secuentes. Las intervenciones para el manejo de...

The findings of a case study assessing the design and implementation of an electronic health record (EHR) in the public health system of Colima, Mexico, its perceived benefits and limitations, and recommendations for improving the implementation process are presented. In-depth interviews and focus group discussions were used to examine the experien...

The world-wide incidence of dengue increased in a spectacular form in the last few decades, approximately a 40% of the world-wide population runs the risk of contracting the disease. The costs of the medical attention, plus the cyclical tendency of Dengue, have become a challenge for the health systems, product of migration, globalization, urbaniza...

Unlabelled: The prevalence of diabetes in Mexico among those 20-64 years of age has increased from 7.2% in 1993 to 10.7% in 2000. National population-based surveys in Mexico demonstrated that 50% of the total population with diabetes had blood glucose levels of 200mg/dl or higher. Thus, diabetes care has become one of the most important public hea...

Background: Today, Mexico faces a complex situation of public health diseases still suffer from underdevelopment, such as those associated with infectious diseases and malnutrition while facing challenges from advanced countries, such as cancer, obesity, heart disease and diabetes. Diabetes is a disease of high prevalence in our country and is undo...

La obesidad y el sobrepeso han modifica-do, sin duda y para siempre, la práctica médica al hacer que muchos especialistas se acerquen al entendimiento y manejo de las enfermedades cró-nicas, independientemente de la especialidad o preferencia terapéutica que tengan, ya que en su gran mayoría estos pacientes son enfermos cróni-cos. En el presente te...

Las enfermedades crónico degenerativas representan un riesgo importante para los paises. Aunado al envejecimiento acelerado que viven muchos otros, hacen que sea compleja su atención. Existe un elevado costo asociado a su atención y sobre todo un elevado costo de oportunidad en las poblaciones jóvenes, toda vez que se está presentando el fenomeno d...

Title A. Diabetes and Associated Risk Factor along the US-Mexico border. Results from the US- Mexico Border Diabetes Prevention and Control Project Purpose of the study B. To assess the prevalence of diabetes, its risk factors, and access to health in adults from the U.S.-Mexico border. To plan the development of a bi-national diabetes preven...

El gobierno federal desarrolla acciones para reducir la mortalidad por las �enfermedades crónicas no transmisibles� (ECNT). Una de ellas es la creación de unidades médicas de especialidad (Uneme) diseñadas para el tratamiento especializado de las ECNT (sobrepeso, obesidad, riesgo cardiovascular y diabetes). La intervención se basa en la participaci...

The federal government has implemented several strategies to reduce mortality caused by chronic non-communicable diseases (CNTD). One example is the development of medical units specialized in the care of CNTD (i.e. overweight, obesity, cardiovascular risk and diabetes), named UNEMES (from its Spanish initials). These units--consisting of an ad-hoc...

to determine the relationship between the abdominal obesity and cardiovascular risk factors in apparently healthy subjects from Mexico City. a total of 186 apparently healthy men and nonpregnant women from Mexico City, were enrolled in a cross-sectional study. A detailed medical history and physical examination were performed. Abdominal obesity was...

We undertook this study to establish the prevalence of overweight, obesity, abdominal obesity, high blood pressure, and high glucose and triglyceride levels in school-age children from Mexico City, as well as to determine how overweight and obesity are related to the other risk factors. The study was a cross-sectional survey comprised of 1819 child...

Proactive worksite strategies that change the physical or sociocultural environment(s) to incorporate obligatory physical activity may be necessary to engage sedentary people. This study describes implementation and evaluation of an intervention, Pausa para tu Salud (Pause for Your Health), that integrated a brief period of group exercise into the...

Introduction: Proactive worksite strategies that change the physical or sociocultural environment(s) to incorporate obligatory physical activity may be necessary to engage sedentary people. This study describes implementation and evaluation of an intervention, Pausa para tu Salud (Pause for Your Health), that integrated a brief period of group exer...

Objective: To estimate the frequency of abdominal obesity among a sample of Mexican patients and their primary care physicians. Methods: A convenient sample of primary care physicians were randomly selected in six large cities of Mexico. Every physician enrolled an arbitrary number of patients, aged between 18 and 80 years, excluding pregnant women...

To elaborate Mexican growth charts based on international methodology. Data were obtained from the Mexican National Health Survey. The survey was stratified and probabilistic representative of all the country. Nationwide open population living in urban and rural areas. Boys (8545) and girls (9983) from 10 to 18 years participating in the survey. Ag...

Atherosclerotic ischaemic heart disease is the second leading cause of general mortality in Mexico due to the growing prevalence of atherosclerotic risk factors in our society. The data of the FRIMEX study (Factores de Riesgo en México, Risk Factors in Mexico), considered together with those of other contemporary epidemiological surveys, will aid i...

Las enfermedades cardiovasculares representan la principal causa de morbilidad y mortalidad. El 25% de los fallecimientos por debajo de los 60 años de edad está relacionado con las enfermedades crónicas no transmisibles. Estos padecimientos son más frecuentes en países en vías de desarrollo; los cambios en los hábitos alimenticios con altos conteni...

Cardiovascular diseases are the main cause of death and disability in México. 25% of deaths under 60 years of age are related to chronic degenerative diseases. These disorders are more common in developing countries and are caused by an excessive intake of fatty acids, sodium, alcohol, tobacco consumption and decrease in physical activity. The prev...

Background: The fast epidemiological transition that occurred in Mexico for several decades has increased the importance of the chronicdegenerative diseases, particularly, those of cardiovascular origin. Factors as the systemic arterial hypertension, hypercolesterolemia, smoking, disglucemic condition and obesity are determinants of cardiovascular...

Objective: To know the percentage of patients with diabetes type 2 that receive insulin as part of their treatment. Material and method: In three different cities (areas) of the Mexican Republic a survey was applied to patients with diabetes. In this survey it was possible to identify age, sex, residence, type of diabetes, type of insulin and how l...

A study on the treatment of obese adolescents with the use of sibutramine in private practice is presented. Patients consisted of 24 boys and 43 girls with obesity (body mass index [BMI]>85th percentile sex-specific BMI for age and sex) ranging from 12 to 18 years of age. Patients were given sibutramine 10 mg per day for 6 months. With the last obs...

A number of cross-sectional or serial studies have demonstrated the clinical impact of microproteinuria and macroproteinuria by identifying individuals at risk of both end-stage renal disease and major cardiovascular events. This study focused on the prevalence of proteinuria in Mexico and its relationship with other cardiovascular risk factors suc...

Background: Most of the non transmissible chronic diseases of high prevalence can be prevented. For this, it is important to identify prediction factors that allow us to create strategies in order to reduce its presentation. Objective: To propose the application of low height and waist perimeter as tools to predict the risk of non transmissible chr...

Propósito: A través de una Re–encuesta Nacional sobre Hipertensión Arterial Sistémica (HTAS) y Factores de Riesgo Cardiovascular, en población adulta con HTAS identificada en encuestas nacionales de salud del año 2000; Determinar: 1) Las tasas de morbilidad y mortalidad. 2) La incidencia e interrelación en el tiempo con otros factores de riesgo, ta...

Objective: Based on a National Re-survey on Hypertension (HTA) and other cardiovascular risk factors performed in Mexico during 2003 and 2004 in the adult population with HTA, as identified in the 2000 National Survey of Health, this study was planed to determine: 1) morbidity and mortality rates; 2) the incidence and interrelation with other risk...

To determine the prevalences of overweight, obesity, type 2 diabetes mellitus (DM) and hypertension (HT) in the Mexican population and compare them with those of a previous Mexican urban survey and an American survey. A structured, randomised, nationally representative Mexican sample was compared with a 1993 Mexican urban survey and the US Third Na...

Objectives To determine the prevalences of overweight, obesity, type 2 diabetes mellitus (DM) and hypertension (HT) in the Mexican population and compare them with those of a previous Mexican urban survey and an American survey. Design A structured, randomised, nationally representative Mexican sample was compared with a 1993 Mexican urban survey...

Objective: To evaluate the accomplishment of the treatment basic goals of every person with diabetes type 2 that attend the Mutual Help Groups (GAM) of the Mexican Ministry of Health (SS). Material and methods: This transversal comparative study was carried out in 15 Mexican states, through the accomplishment reports of the treatment basic goals of...

To assess the ability of the body mass index (BMI) to detect obesity-associated morbidity in subjects with a normal or short stature. Information was obtained on 119 975 subjects from a cardiovascular risk factors detection program. Standardized questionnaires were used. Capillary glucose and cholesterol concentrations were measured. Diabetes, arte...

To evaluate the accomplishment of the treatment basic goals of every person with diabetes type 2 that attend the Mutual Help Groups (GAM) of the Mexican Ministry of Health (SS). This transversal comparative study was carried out in 15 Mexican states, through the accomplishment reports of the treatment basic goals of the GAM integrants by June of 20...

Aims: To know the prevalence and the interaction among the principal cardiovascular risk factors such as hypercholesterolemia (HCL), hypertension (HTA), overweight, carbohydrates metabolism disturbances, and smoking, an urban survey was performed in the six Mexican Republic states, where the national population is more concentrated. Methods: This s...

To establish the prevalence of overweight and obesity in Mexican children 10 to 17 years of age according to the percentiles from both the Centers of Disease Control and Prevention (CDC) and the International Obesity Task Force (IOTF). Heights and weights were measured in children from nationally representative, randomly chosen households in the Me...

To know the prevalence and the interaction among the principal cardiovascular risk factors such as hypercholesterolemia (HCL), hypertension (HTA), overweight, carbohydrates metabolism disturbances, and smoking, an urban survey was performed in the six Mexican Republic states, where the national population is more concentrated. This survey was trans...

To describe the clinical characteristics of the diabetic population that formed part of a population-based survey conducted in México. In 2000, information was obtained from 42,886 subjects aged > or =20 years using a multistage sampling procedure. Standardized questionnaires were used. Anthropometric measurements, blood pressure, and capillary glu...

To determine optimum anthropometric cutoffs for predicting the likelihood ratios of type 2 diabetes mellitus (DM) and hypertension (HT) in Mexicans. Data from a randomly selected, nationally representative health survey (2000) with 11,730 men [37.4 (+/- 12.9) years] and 26,647 women [37.3(+/- 12.9) years] were assessed for values of body mass index...

Purpose: To determine the prevalence and interrelation of noncommunicable chronic diseases (NCCD), obesity, smoking, and proteinuria in the adult population (between 20 and 69 years of age) of Mexico, and their stratification according to age, gender, and geographical area. Method: During the year 2000, a probabilistic national survey was performed...

To determine the prevalence and interrelation of noncommunicable chronic diseases (NCCD), obesity, smoking, and proteinuria in the adult population (between 20 and 69 years of age) of Mexico, and their stratification according to age, gender, and geographical area. During the year 2000, a probabilistic national survey was performed in 45,300 person...

Aims. Hypertension remains as a major cause of cardiovascular morbidity in México. The Health National Survey 2000 of México was performed to analyze the current status of the prevalence of some risk factors such as diabetes, hypertension (HTA), obesity, smoking, and proteinuria. Methods. A National Survey was carried out in México where 45,300 ind...

Hypertension remains as a major cause of cardiovascular morbidity in México. The Health National Survey 2000 of México was performed to analyze the current status of the prevalence of some risk factors such as diabetes, hypertension (HTA), obesity, smoking, and proteinuria. A National Survey was carried out in México where 45,300 individuals betwee...

Objective: To estimate the frequency of abdominal obesity among a sample of Mexican patients and their primary care physicians. Methods: A convenient sample of primary care physicians were randomly selected in six large cities of Mexico. Every physician enrolled an arbitrary number of patients, aged between 18 and 80 years, excluding pregnant women...