Adrielle Rodrigues Costa

• Master's Student at Universidade Regional do Cariri

Plant extracts serve as a reservoir of bioactive phytochemicals applicable in various domains, with Gossypium hirsutum L. encompassing constituents such as terpenes, phenolic compounds, and flavonoids, all exhibiting notable antioxidant properties, as well as metal-reducing capabilities, alongside potential toxicity. These compounds are distributed...

The growing bacterial resistance represents a global challenge, making it necessary to search for new therapeutic approaches, such as the use of medicinal plant extracts, to combat resistant microorganisms. Among these species, Erythroxylum rosuliferum O.E. Schulz has stood out due to the promising potential of the Erythroxylum genus, known for its...

Photosynthesis stands out as one of the most important mechanisms for maintaining terrestrial life. However, the means by which photosynthesis occurs are sometimes so complex that they make the teaching and learning process difficult. The objective was to characterize and compare the performance of research in the teaching of Plant Physiology, espe...

The increasing spread of bacterial resistance represents a serious threat to global health. Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli are clinically relevant bacteria driving the search for new strategies to combat resistance. Plant products have emerged as promising alternatives. This study investigated the presence of ph...

Salinity stress is one of the main abiotic factors that negatively impact plant growth and productivity. Continuous exposure to NaCl leads to the accumulation of ions such as sodium (Na⁺), chloride (Cl⁻), and sulfate (SO₄²⁻) in plant cells, impairing nutrient absorption and causing cellular and tissue damage. Therefore, it is necessary to find alte...

Objective: This work aimed to elucidate the chemical profile and the allelopathic potential of the ethanolic extract of Asparagus setaceus leaves collected in the morning (8 A.M) and afternoon (2 P.M). Method: The extract was obtained using cold ethanol and the secondary metabolites classes were identified with specific reagents. For allelopathic a...

Antimicrobial resistance is a global concern, affecting public health and generating economic and social impacts, which requires global strategies to contain its spread and reduce associated deaths. Medicinal plants demonstrate efficacy against pathogenic microorganisms, offering alternatives in the fight against microbial resistance. As a highligh...

Objective: This work aimed to elucidate the chemical profile and the allelopathic potential of the ethanolic extract of Asparagus setaceus leaves collected in the morning (8 A.M) and afternoon (2 P.M). Method: The extract was obtained using cold ethanol and the secondary metabolites classes were identified with specific reagents. For allelopathic a...

This study aims to investigate the essential oil from leaves of Eugenia pohliana (EOEP) in regard to its chemical composition, antimicrobial and drug‐enhancing activity, as well as the reduction of fungal virulence capacity. Chemical characterization using GC‐MS showed as major components the sesquiterpenes δ‐cadinene, Epi‐α‐Muurolol, and bicycloge...

Objective: The objective of this work was to obtain the chemical profile and verify the biological activities of ethanolic extract from the leaves of Asparagus setaceus. Method: The extract was obtained with cold ethanol and the classes of secondary metabolites were identified with specific reagents. The antibacterial assays were performed using th...

Multidrug-resistant bacteria have complicated the treatment of gastrointestinal diseases; their microbial resistance stems from the indiscriminate use of medications and the transfer of resistance genes. Varronia curassavica Jacq., a plant traditionally used to treat rheumatic and gastrointestinal diseases in underserved populations, has sparked in...

The discovery of penicillin by Alexander Fleming in 1928 marked the beginning of the antibiotic era but also led to the development of resistant bacterial strains. Bacterial resistance, worsened by the improper use of antibiotics, has become a growing concern. Phytotherapy, particularly using medicinal plants, emerges as a promising alternative for...

É com grande entusiasmo que apresentamos o quarto volume desta bem-sucedida coletânea de estudos intitulada “Tópicos em ciências da saúde: contribuições, desafios e possibilidades”. Nesta edição, selecionamos artigos, revisões, relatos de caso ou experiência de relevância científica no amplo panorama das Ciências da Saúde. Seguindo o alto padrão do...

Candida species are normally commensal yeasts residing in the human body, under certain circumstances, can trigger pathological conditions such as candidiasis, not to mention antifungal resistance. Lippia sidoides Cham., or pepper-rosmarinus, is a native plant found in the Northeastern semi-arid region of Brazil, cited in ethnobotanical studies for...

O presente trabalho teve como objetivo realizar a avaliação do perfil químico e a atividade antibacteriana do extrato etanólico das folhas de Chenopodium ambrosioides L. contra as bactérias Streptococcus pneumoniae e Klebsiella pneumoniae. Suas folhas foram coletadas e submetidas a testes no município de Juazeiro do Norte- CE. O extrato etanólico f...

The global antibiotic resistance crisis highlights the inappropriate use of medicines by the population and the lack of development of new antimicrobial agents. According to various studies, natural products are promising alternatives for combating bacterial resistance and treating infectious diseases. Accordingly, the present study aimed to analyz...

As microbes develop resistance to various drugs, the treatment of infections becomes increasingly challenging, leading to prolonged illness, heightened severity of infections, elevated mortality rates, and increased healthcare costs. Essential oils are lipophilic and volatile mixtures of compounds that have gained attention in research for novel an...

This study performed a comprehensive bibliometric analysis of research on Anacardium occidentale (AO) up to September 2021, based on Scopus records. Anacardium occidentale (AO) is a plant species commercially available in agricultural sector. The bibliometric analyzes were fragmented into four stages, that is, data acquisition, data pre-processing,...

This article presents a systematic review addressing the effects of the nutraceutical myricetin on liver health. Nutraceuticals are natural or bioactive substances known for their health benefits and their crucial role in the prevention and treatment of liver diseases. In this context, myricetin, a flavonoid found in various food sources, emerges a...

Desde tempos antigos, as plantas têm sido fontes de alimento e medicina, sendo amplamente adotadas, especialmente em comunidades carentes. Apesar do progresso médico, aproximadamente 75% da população global ainda depende das propriedades curativas das plantas. A narrativa destaca a influente expedição liderada por Carl Friedrich Philipp von Martius...

Antibiotic resistance is a significant public health problem resulting from inadequate information about the incorrect use of antibiotics and patient pressure for prescriptions. These factors contribute to indiscriminate use, which poses a risk to public health. The study focused on the Basic Health Unit (BHU) in the municipality of Missão Velha, C...

This study aimed to evaluate the antibiotic effects of the fixed oils of Acrocomia aculeata (FOAA) and Syagrus cearenses (FOSC) against the bacterial strains and the fungi strains of the genus Candida spp. The method of serial microdilution using different concentrations was used for measuring the individual biological activity of the fixed oils. T...

Paullinia cupana (Kunth), popularly known as guarana, is a plant species from the Amazon Region of Brazil that stands out for being one of the most promising herbal medicines of the Brazilian flora since it has relevant biological properties. However, studies are still needed to use this species as a direct approach to evaluate aspects related to b...

Microbial resistance has become a worrying problem in recent decades after the abusive use of antibiotics causing the selection of resistant microorganisms. In order to circumvent such resistance, researchers have invested efforts in the search for promising natural substances, such as essential oils. Thus, the objective of this work was to determi...

Abstract Mannose/glucose-binding lectin from Canavalia ensiformis seeds (Concanavalin A - ConA) has several biological applications, such as mitogenic and antitumor activity. However, most of the mechanisms involved in the in vivo toxicity of ConA are not well known. In this study, the Drosophila melanogaster model was used to assess the toxicity a...

To understand the influence of environmental factors on the metabolic diversity of phytochemical compounds from extracts of leaves and bark of Anacardium occidentale, collected in two different geographic areas, ultraperformance liquid chromatography and mass spectrometry were used, as well as the composition of physicochemical properties of both s...

Species of the genus Miconia are used in traditional medicine for the treatment of diseases, such as pain, throat infections, fever, and cold, and they used as depuratives, diuretics, and sedatives. This work reviewed studies carried out with Miconia species, highlighting its ethnomedicinal uses and pharmacological and phytochemical potential. This...

One of the main global problems that affect human health is the development of bacterial resistance to different drugs. As a result, the growing number of multidrug-resistant pathogens has contributed to an increase in resistant infections and represents a public health problem. The present work seeks to investigate the chemical composition and ant...

Mesosphaerum suaveolens (L.) Kuntze is a species widely used traditionally in the treatment of ailments, such as stomach pain, hemorrhoids, cough, verminosis, ulcer, liver disease, fever, influenza, nasal congestion, and inflammation. is review aims to provide a survey of available information on seven international electronic databases (Google Sch...

Thiazolidine compounds NJ20 {(E)-2-(2-(5-bromo-2-methoxybenzylidene)hydrazinyl)-4-(4-nitrophenyl)thiazole} and NW05 [(2-(benzo (d) (1,3) dioxol-4-ylmethylene)-N-(4-bromophenyl)-thiosemicarbazone] potentiated the effect of norfloxacin in resistant bacteria; however, there are no reports on their effects on Nauphoeta cinerea in the literature. The ob...

Popularly, the fixed oil from the fruits of Caryocar coriaceum Wittm. extracted by extractivists from Chapada of Araripe, it is used for the treatment of various diseases, especially for the treatment of infectious and parasitic diseases. Due to this popular use, it was hypothesized that this product had an effect against pathogenic microorganisms....

Background Saline stress is an important environmental factor that limits the productivity of numerous agricultural crops, such as onion (Allium cepa L.), a vegetable present in gardens and used in various ways. Pulegone has been identified as a component that has a large number of biological functions. Objective The aim of this study was to inves...

The barks of Anacardium occidentale (cashew tree) been used for centuries in the popular pharma-copoeia of South America and West Africa for the treatment of infections and neurodegenerative diseases. Thus, this work aimed to evaluate the biological effect of the ethanolic extract of the barks against strains of Candida spp. and cancer cell lines,...

In recent decades, fungal infections have been increasing, as well as the indiscriminate use of large-scale antifungal. The objective of the present study was to characterize the chemical components of L. montevidensis leaf essential oil (EOLm) and evaluate its antifungal potential and fluconazole modulating activity against Candida strains. The es...

Mercury chloride (HgCl2) acts as a bioaccumulator capable of causing numerous neurological and physiological changes in organisms in a negative way. However, rutin has been considered a very effective antioxidant compound in the treatment of neurodegenerative diseases, as it can neutralize radicals capable of damaging neuronal cells. In this contex...

Dados cientométricos no contexto "desenvolvimento sustentável no Brasil" nos últimos 10 anos Scientometric data in the context "sustainable development in Brazil" in the last 10 years Datos cientométricos en el contexto "desarrollo sostenible en Brasil" en los últimos 10 años

A preocupação com o desenvolvimento sustentável representa a possibilidade de garantir mudanças sociopolíticas que não comprometam os sistemas ecológicos e sociais que sustentam a vida. Neste contexto, foi realizado um levantamento bibliográfico e cientométrico em termos de desenvolvimento sustentável, ferramentas importantes para estudar e mensura...

Objetivou-se realizar uma revisão bibliográfica acerca das atividades biológica e farmacológica de Rhaphiodon echinus. Trata-se de uma revisão integrativa norteada pela seguinte pergunta: Quais as evidências cientificas acerca da atividade biológica e farmacológica da R. echinus? Elegeu-se as bases: MEDLINE, PUBMED, BDENF, SCOPUS e WoS para a pesqu...

Alelopatia é definida pela Sociedade Internacional de Alelopatia como a ciência que estuda qualquer processo envolvendo essencialmente os metabólitos secundários produzidos pelas plantas, algas, bactérias e fungos que influenciam o crescimento e desenvolvimento de sistemas agrícolas e biológicos, incluindo efeitos positivos e negativos. Entretanto,...

Products of natural origin with potential chelating or reducing Fe+ free become promising in antioxidant research, because they have the ability to soften transition metals that can cause cellular damage by oxidative stress. Thus, the aim of this study is to promote the evaluation of the antioxidant potential of essential oil by the orthophenanthro...

There is a growing search in the chemical composition of essential oils, as they have biological and pharmacological activities. Among the plants with homogeneous composition in essential oils stands out the species Eremanthus arboreus (Gardner) MacLeish, (Asteraceae) popularly known as the “candeeiro”. This plant species is native to Chapada of Ar...

Anacardium occidentale (Anacardiaceae), popularly known as cashews, is a vegetable native to South America, consumed worldwide in the food sector. Its leaves and bark are used in the preparation of teas for health maintenance, being indicated in ethnobotanical studies for the treatment of cancer, which is considered a serious public health problem...

Plants are considered a rich source of bioactive compounds and an alternative agent for insect control. Among them, representatives of the Lamiaceae family are the best known for this potential, as they produce volatile compounds with insecticidal activities, known as essential oils, as is the case with Ocimum gratissimum. In this way, the present...

The use in folk medicine of leaves of Mesosphaerum suaveolens for the treatment of diseases of the digestive system and respiratory system, raised the hypothesis that its volatile oil has biological properties against pathogenic microorganisms. To evaluate this hypothesis, the antibacterial, antifungal activity against Candida yeast strains, which...

The plants produce a variety of compounds that are not directly associated with their growth and are derived from their secondary metabolisms. Such compounds can be used in the formulation of bioherbicides, in the control of weeds. Among the chemical groups that most present allelopathic actions are the phenolic compounds which are present the flav...

The emergence of fungal resistance to commercial drugs has been a major problem for the WHO. In this context, research with natural products is promising in the discovery of new active substances. Thus, this work evaluated the antifungal effect of a medicinal plant (i.e., Mesosphaerum suaveolens) against strains of the genus Candida, tested the com...

Essential oils are compounds produced by secondary plant metabolites and are found in leaf trichomes, moreover, they are characteristic because they present strong odors and present biological activities. Thus, the objective of this work was to evaluate the insecticidal action of Mesosphaerum suaveolens essential oil against nymphs of Nauphoeta cin...

The use of cactus for forage may cause soil contamination by allelochemicals in order to compromise the future planting or even reforestation of that site. The objective of this work was to evaluate the allelopathic action of cladodes and roots of Cereus jamacaru, Pilosocereus gounellei and Tacinga inamoena on the germination and development of Cen...

The oil presented the α-Terpinene as the major compound with 54.09% presence. Antibacterial activity demonstrated significant MIC against Staphylococcus aureus (256 μg/mL) and moderate against Pseudomonas aeruginosa (512 μg/mL). The modulating effect of antibiotics was significant against P. aeruginosa potentiating the effect of all the antibiotics...

Mesosphaerum suaveolens (L.) Kuntze (Lamiaceae), conhecida como "bamburral", é utilizada na medicina popular, entretanto, pouco se sabe dos constituintes químicos dela, os seus efeitos tóxicos e terapêuticos. Caracterizar os compostos polifenólicos dos extratos de M. suaveolens, bem como a sua atividade antioxidante e tóxica. Os componentes químico...

Introduction: Tarenaya spinosa (Jacq.) Raf. (Cleomaceae), mussambe, stands out for its strong smell, which is produced by its essential oil. Oils originating from secondary metabolism display biological activities such as insecticidal, antifungal, larvicidal, and others. Objective: Evaluate the insecticidal and larvicidal activity of oil from T. sp...

Introduction: Fungal infections, particularly those caused by the genus Candida, are an important public health problem. Lantana camara L. stands out among the medicinal species with abundant biological and pharmacological activity. Objective: Analyze the phytochemical profile of essential oil of L. camara and evaluate its antioxidant capacity and...

Hyptis suaveolens (L.) Poiteau, known as “Bamburral” is a plant widely used in Brazilian folk medicine, however, there are no toxicological studies to ascertain its safety. Thus, we aimed to investigate the phytochemical and toxic effects of essential oil and infusion of the dry leaves of H. suaveolens in Drosophila melanogaster and Artermia salina...

The association of herbal products with standard antimicrobial drugs has recently gained more attention as a hope to overcome infectious diseases caused by multidrug-resistant microorganisms. Here, we investigated for the first time the antimicrobial (antifungal and antibacterial) activity of ethanolic and aqueous extracts of R. echinus against mul...

Introduction: The use of plants as insecticides may be an alternative to many synthetic products because their toxicity to animals is low and they are easily biodegradable in the environment. The species Lantana montevidensis (Spreng.) Briq. (Verbenaceae), chumbinho, is a subshrub rich in secondary metabolites it uses for its own defence. The exper...

Rev Cub de Plant Med. 2017;22(1) ARTÍCULO ORIGINAL Estudo químico-biológico do óleo essencial de Lantana montevidensis (chumbinho) (Spreng.) Briq. (Verbenaceae) contra Drosophila melanogaster Estudio químico-biológico del aceite esencial de Lantana montevidensis (Chumbinho) (Spreng.) Briq. (Verbenaceae) contra Drosophila melanogaster Chemical-biolo...

Introduction: Leishmaniasis is a complex of tropical diseases caused by more than twenty different species of intracellular protozoa from the genus Leishmania. Chagas disease is one of the main public health problems in many countries. It mostly affects the poor, rural population. Melissa officinalis L. is a perennial herb, an exotic plant from the...

A especie Lantana camara L., camara, pertencente a Familia Verbenaceae tipica das Americas e Africa, nativa do Brasil e Uruguai e um arbusto infestante e ornamental, distribuidas por todos os Estados brasileiros. As folhas dessa especie tem sido utilizadas popularmente no tratamento de coceiras, dor de estomago, dente, reumatismo, cortes, gripe, as...

Protoco de bioensaio de toxicidade com Artemia salina Leach.