Adriana Campos Passanezi Sant'Ana

Adriana Campos Passanezi Sant'Ana
University of São Paulo | USP · Departamento de Prótese (FOB) (Baurú)

PhD

About

106
Publications
34,899
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1,281
Citations
Additional affiliations
August 2002 - present
University of São Paulo
Position
  • Professor (Associate)
Education
February 1990 - December 1993
University of São Paulo
Field of study
  • Bauru Dental School

Publications

Publications (106)
Article
Aim: This study aims to evaluate and validate the sensibility and the level of agreement between different gingival color measures obtained by a spectrophotometer (SPECTRO) and a photography (PHOTO) method. Methods: Among 40 patients, the color was measured 2 mm apical to the gingival margin by CIE L*, a*, b* system using a reflectance spectrophoto...
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Objective: Gestational diabetes mellitus (GDM) causes maternal and infant morbidity. Periodontitis is associated with adverse pregnancy outcomes. The aim of this study was to evaluate periodontal status, prematurity and associated factors in pregnant women with and without GDM. Methods: This observational cross-sectional study included 80 pregna...
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Eficácia das tecnologias de bloqueio dos tubos dentinários para tratamento da hipersensibilidade dentinária em pacientes periodontais-estudo piloto Eficacia de las tecnologías de bloqueo de los túbulos para la hipersensibilidad dentinaria en pacientes periodontales-estudio piloto Abstract Periodontal patients often report dentin hypersensitivity (D...
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Recently, the use of type I collagen obtained from Nile Tilapia (Oreochromis niloticus) was proposed for the treatment of second and third-degree burning lesions and diabetic ulcers due to its occlusive and healing properties. The aim of this report is to describe the use of Nile tilapia skin as an occlusive barrier to protect palatal wounds after...
Article
In vitro evaluations are essential to gaining a better understanding of re-osseointegration, while reducing animal use and the overall costs of peri-implantitis studies. This pilot study evaluated preosteoblast migration from 3-D-printed scaffolds to decontaminated titanium microimplants, creating a system that tries to mimic the bone–implant inter...
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The purposes of this study are to evaluate the effects of photobiomodulation (PBM) with laser and LED on rat calvaria osteoblasts (rGO lineage), cultured in osteogenic (OST) or regular (REG) medium, after induction of a quiescent state and to test if PBM is capable of osteogenic induction and if there is a sum of effects when combining OST medium w...
Article
Aims: Gingival recession has been associated with dentin hypersensitivity and aesthetic impairment. The impact of gingival recession and periodontal surgical procedures on adult patients' quality of life are scarce. The aim of this study was to evaluate the quality of life of patients submitted to root coverage procedures with subepithelial connec...
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Systemic lupus erythematosus (SLE) is a complex chronic autoimmune disease characterized by tissue damage and widespread inflammation in response to environmental challenges. Deposition of immune complexes in kidneys glomeruli are associated with lupus nephritis, determining SLE diagnosis. Periodontitis is a chronic inflammatory disease characteriz...
Article
This randomized split-mouth preliminary clinical trial aimed to evaluate periodontal parameters and gingival blood flowmetry, comparing sites that received subepithelial connective tissue graft from the palate after deepithelialization (DE) or obtained with parallel incision (PI). Periodontal parameters were evaluated at baseline and 6 months posto...
Article
Aim This prospective cohort study evaluated late complications (LC) on recipient sites comparing two types of connective tissue grafts (CTG). Materials and Methods Participants (n: 60) were treated with coronally advanced flap (CAF) plus CTG harvested by de‐epithelialized technique (DE) (n:31) or two‐parallel incision (PI) (n:29). Areas were evalu...
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Purpose To investigate the influence of implant surface decontaminated and uncontaminated on osteoblast-like cell adhesion and proliferation Materials and methods Commercially available implants of different brands and surface characteristics were selected: Biomet 3i® Nanotite (NT) and Osseotite (OT) , Straumann® SLActive (SLA), and Neodent® Acqua...
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Background The aim of this preliminary study was to analyze the effectiveness of three different protocols of decontamination on five commercial moderate rough implants. Material and methods The types of implants investigated were: Neoporos Drive CM (CM; Neodent®), Drive CM Acqua (ACQ; Neodent®), SLActive (SLA; Straumann®), Osseotite (OT; Biomet 3...
Article
Background: This split-mouth randomized clinical trial compared two different types of subepithelial connective tissue grafts (SCTG) considering clinical parameters and patient-centered outcomes in patients with bilateral recession type 1 multiple gingival recessions after 6 months postoperatively. Methods: A total of 21 patients were surgically...
Article
Background: Previous data suggest that bone demineralization may promote bone graft consolidation as well as proliferation and differentiation of pre-osteoblasts, but the biological mechanisms involved in this process need to be clarified. This study investigated the effects of bone demineralization with citric acid (CA) and tetracycline (TCN) on...
Article
Background: Bone demineralization has shown to be advantageous in autogenous onlay bone grafts and in pre-osteoblasts cultures, but such procedure has never been evaluated in particulate bone grafts. This study aimed to investigate the role of two demineralizing agents in the repair of the 8-mm critical-size defects in rats' calvaria. Methods: E...
Article
Gingival recessions are a highly prevalent issue that is often associated with interproximal tissue deficiency. An intervention in these scenarios is of extreme importance since these defects can lead to aesthetic, phonetic and other dental problems. Unfortunately, the treatment of advanced gingival recessions is a major challenge in periodontics b...
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Purpose: The aim of this study was to investigate the response of osteogenic cell lineage and gingival fibroblastic cells to different surface treatments of grade IV commercially pure Titanium (cpTi) disks. Material and methods: Grade IV cpTi disks with different surfaces were produced: machined (M), sandblasting (B), sandblasting and acid subtr...
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Objectives This study evaluated clinical outcomes of acellular dermal matrix (ADM) allograft compared with autogenous free gingival graft (FGG) for gingival augmentation after 15 years. Material and methods Twenty-two patients were originally included and evaluated by de Resende et al. (Clin Oral Investig 23:539–550, 2019), and 12 accepted to part...
Article
Background: The aim of this study was to evaluate the cytotoxicity of cyanoacrylate adhesives in an indirect contact assay in human gingival fibroblast (FGH) and oral osteoblasts (GO) lineages. Methods: Cover glasses were glued with adhesives following the ISO 10993-2012 protocol. The groups were: C (control with cells and regular Dulbecco Modifie...
Article
Root conditioners are used to promote root surface biomodification to increase the success rate of root coverage. Citric acid and tetracycline are commonly used. There is recent indication for using antimicrobial photodynamic therapy (aPDT) with this purpose. The aim of this study is to evaluate the effects of citric acid/tetracycline gel and aPDT...
Article
Photogrammetry is a mathematical technique that generates three-dimensional coordinates of specific points identified from multiple images of the same object obtained at different angles. This technique may be a low-cost alternative for traditional scanning. The objective of this proof of concept was to evaluate the accuracy and precision in obtain...
Article
Background and Objective The aim of this interventional, parallel‐assignment, single‐blinded, randomized, efficacy study was to investigate the efficacy of the treatment of gingival recessions by osteogenic cell transfer. This is the first randomized clinical trial of this nature. Material and Methods Treatment of Miller class I or II gingival rec...
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Previous studies have shown substances capable of similar effects of demineralization, accelerating the process of bone remodeling. This study investigated preosteoblasts behavior in cell culture after bone demineralization with citric acid and tetracycline. Seventy‐four Wistar rats provided 144 calvarial bone samples, 126 of which were randomly di...
Article
The main treatment of periodontal disease is the mechanical removal of supra and subgingival biofilm. Adjuvant therapies as antimicrobial photodynamic therapy (aPDT) may offer improved clinical and microbiological results. The aim of this in vitro study was to evaluate the effect of toluidine and methylene blue dyes, associated with red laser and L...
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This article deals with establishing a new link between trauma from occlusion and periodontal pockets based on the know‐how and background gradually developed. To provide a better understanding to the reader, a historical perspective is firstly presented. The main features on the controversy of the role played by trauma from occlusion on the physio...
Article
A 47-year-old Caucasian male presented with a radiolucent area around the apical region of an implant placed using the socket shield technique. A second surgical procedure was performed to curette the lesion and fill the defect with a xenogeneic bone graft. Twenty months after implant placement and 10 months after the second surgery, there was no s...
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A reabilitação de pacientes parcialmente desdentados é um tratamento viável e com excelente prognóstico. Todavia, a disponibilidade óssea em altura é um fator crucial para o sucesso desse tratamento. O levantamento de seio maxilar, apesar da baixa qualidade óssea da maxila posterior, é considerado um procedimento bastante previsível. Entretanto, té...
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Objetivo: revisar a literatura sobre o tratamento das doenças periodontais associado à probióticos, identificando as funcionalidades e os principais agentes microbianos empregados. Material e método: foi realizada busca nas bases de dados eletrônicas PubMed e ScienceDirect, empregando os termos de busca probiotics e periodontal diseases. Como crité...
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Purpose: The objective of this study was to investigate the impact of oral health on the quality of life of patients with head and neck cancer (HNC) before and after oncologic treatment. Methods: Forty cancer-free individuals (Cf group) and 40 HNC patients (Hnc group) were included in this study. Hnc group was also divided into two subgroups: Hn...
Article
Aim Orthodontic implant site augmentation was proposed for exodontia of a hopeless tooth to improve bone architecture before implant installation. However, the use of orthodontic appliances to perform slow vertical movements and tooth extraction demands an interdisciplinary approach, increasing time and costs. The aim of this study is to present a...
Article
Background The granulation tissue (GT) present in surgically‐created early healing sockets has been considered as a possible source of osteoprogenitor cells for periodontal regeneration, as demonstrated in animal studies. However, the in vitro osteogenic properties of tissue removed from human surgically‐created early healing alveolar defects (SC‐E...
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Pacientes com necessidades especiais (PNE) representam uma porcentagem significativa da população brasileira, correspondendo a 24% da parcela populacional. Entretanto, esses pacientes podem enfrentar diversas barreiras de acesso ao tratamento. O objetivo desse trabalho é conhecer as percepções e dificuldades encontradas por estudantes de Odontologi...
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Root demineralization is used in Periodontics as an adjuvant for mechanical treatment. The aim of this study was to evaluate the effects of root surface modification with mechanic, chemical, and photodynamic treatments on adhesion and proliferation of human gingival fibroblasts and osteoblasts. Root fragments were treated by scaling and root planin...
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Purpose: This animal study investigated vertical bone formation (VBF) around implants and used histomorphometric analysis to compare different bone-filling materials associated with a massive titanium dome as a tissue barrier. Materials and methods: Seven dogs were submitted to surgical procedures with extraoral access to the lower edge of the m...
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D Vitamin (calciferol) presents an important role in bone metabolism (turnover) and maintenance of calcium and phosphorus levels in blood. The main source of production is sun-stimulated skin. However, characteristics of modern life, such as fear of dermatological damage and use of protective agents, have hindered/reduced sun exposure. In this way,...
Article
O estresse psicológico está relacionado com a Periodontia como um dos fatores da etiopatogenia da doença periodontal (DP) através da interação com o sistema neuroendócrino imunológico. Entre os marcadores biológicos que medem níveis de estresse encontram-se cortisol, α-amilase e cromogranina A (CgA). Esta revisão de literatura baseou-se na pergunta...
Article
Objective: The aim of this study was to compare the effect of root biomodification by lasers, citric acid and antimicrobial photodynamic therapy (aPDT) on viability and proliferation of human gingival fibroblasts (FGH). Design: Groups were divided in control (CC - only cells), and root fragments treated by: scaling and root planing (positice con...
Article
Pyogenic granuloma is a traumatic lesion that affects the mucocutaneous tissues of oral cavity. It is more prevalent in gingival tissues and in young women. The purpose of this report is to present an atypical case where anatomical features, detectable only by complementary exams, implied on the recurrence of the lesion. A 21-year-old caucasian fem...
Article
Background: The oral squamous cell carcinoma (OSCC) survival rate is influenced by the fact that diagnoses occur mostly in late stages of the disease. Thus, there is a clear contribution in the early findings, making the use of minimally invasive techniques for diagnosis, such as analysis of salivary markers, interesting tools. Methods: A system...
Article
Background and overview: The aim of this study was to describe the effects of bruxism in peri-implant bone loss 6 years after the placement of a successful implant-supported prosthesis, to describe its treatment, and to propose a differential diagnosis of the lesion. Case description: A 62-year-old, nonsmoking, systemically healthy partially ede...
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Objetivo: O objetivo deste artigo foi revisar os dados na literatura sobre possíveis mecanismos que estabeleçam uma relação entre o câncer oral e a doença periodontal. Material e Métodos: Foi realizada uma busca nas bases de dados Pubmed, Scopus e Web of Science por publicações até abril de 2016. Resultados: Os artigos analisados apontaram evidênci...
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The aim of this systematic literature review was to evaluate which type of periodontal preventive and therapeutic approaches presents superior outcomes in patients with Down syndrome (DS). Studies reporting different methods of periodontal care from DS patients were considered eligible. Included clinical studies should indicate at least two periodo...
Data
List of titles selected for full-text analysis and the reasons for inclusion. (DOCX)
Data
List of titles selected for full-text analysis and the reasons for exclusion. (DOCX)
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Focused Clinical Question: How to diagnose, classify and treat cases of Altered Passive and Active Eruption? Summary: Frequently, a Gummy Smile is related to aesthetic problems and is caused by several factors such as: vertical maxillary growth, dentoalveolar extrusion, short upper lip, upper lip hyperactivity, Altered Passive Eruption, (APE), and/...
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Animal model proposition in order to investigate vertical bone regeneration around partially inserted implants in the inferior border of canine mandible.
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Advantages of lip frenectomy with high-intensity diode laser – a case report There are clinical conditions in periodontics where the labial frenulum it is positioned in gingival papillae getting very close to the gingival margin, predisposing the development of recessions, causing diffi culty in cleaning, generating persistent infl ammation, restri...
Article
Black-pigmented bacteria (BPB) are Gram-negative anaerobic, non-motile, proteolytic rods strongly implicated in the pathogenesis of periodontal disease. Although pigments are produced in vitro, black pigmentation is rarely found clinically. However, it may compromise aesthetics and contribute to gingival inflammation. The aim of this report is to d...
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The evaluation of education environment is essential to provide to the professors a better understanding of the teaching process. One valuable tool for this assessment is the Dundee Ready Educational Environment Measure (DREEM). This questionnaire has 50 questions and is divided in five dimensions: D1–Perceptions of teaching, D2–Perceptions of teac...
Poster
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Occlusal trauma may be a co-factor which can increase the rate of progression of an existing periodontal disease. The treatment of occlusal discrepancies as part of periodontal treatment may have beneficial long term effects. Thus, despite extensive research over the years, the role of occlusion in the etiology and pathogenesis of periodontitis is...
Article
Background: Antimicrobial photodynamic therapy (aPDT) in Dentistry has important effects as bacterial destruction in areas with periodontal disease. Some dyes applied in aPDT could present low pH and, consequently, result in tooth demineralization. This study evaluated demineralization produced by aPDT with toluidine blue O (TBO) at low pH and ana...
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Aim: To report a well succeeded use of cyanoacrylate adhesive for fixating a resorbable membrane during a guided tissue regeneration procedure (GTR). Background: The immobilization of membranes in GTR is essential for establishing proper environment for cell differentiation and tissue regeneration. However, some membranes are very difficult to b...
Article
Many techniques and flap designs have been used to treat gingival recession by root coverage, but subepithelial connective tissue graft (SCTG) seems to be the gold standard procedure. In an attempt to improve the healing process and increase the success rate of root coverage, some authors have used root modifiers, including different root condition...
Poster
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A deficiência de altura ou espessura de rebordo ósseo na região superior anterior representa um desafio terapêutico à reabilitação oral suportada por dentes ou implantes. A reanatomização de rebordos atróficos por meio de enxerto de tecido conjuntivo subepitelial tem sido amplamente utilizada para correção estética de rebordo desdentado, porém apre...
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Background: Previous studies have demonstrated that bone demineralization can improve consolidation in bone grafts. The biologic mechanisms underlying this phenomenon remain unclear. Methods: Twelve adult male guinea pigs were used in this experiment. Forty-five bone samples removed from the calvaria of nine animals were divided in groups (n = 9...
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Background: The aim of this systematic review is to evaluate the long-term outcomes of patients with periodontitis submitted to periodontal therapy/maintenance and implant placement. Methods: Studies reporting clinical and/or long-term implant outcomes from partially edentulous patients with periodontitis who were treated and followed periodonta...
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Clinical education in dental practice is a challenge for professionals and students. The traditional method of clinical training in Periodontology usually is based on following the procedure and practicing under supervision, until achieving proficiency. However, laboratory practice is required before direct care in patients. Specific anatomic plast...
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Objetivo: Avaliar a eficacia da matriz colagena suina (MC) no recobrimento radicular (RR) e aumento da faixa de gengiva ceratinizada (CGC) ao redor de dentes e de implantes. Metodos: Foram investigados no MEDLINE ensaios clinicos randomizados comparando a eficacia da MC ao enxerto de conjuntivo subepitelial (ECS) e/ou deslize coronal de retalho (DC...
Poster
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Esta revisão sistemática da literatura teve por objetivo investigar a efetividade do uso da matriz colágena suína (MCS) como substituto alógeno no tratamento das recessões gengivais, aumento da faixa de gengiva ceratinizada, na reconstrução do rebordo alveolar e em procedimentos regenerativos periodontais e peri-implantares. Foram selecionados arti...
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Considering that grafted gingival tissue might have to be adapted to the receptor area and that fibroblasts have the ability to respond to bacterial stimuli through the release of various cytokines, this study investigated whether fibroblasts from the palatal mucosa behave differently when grafted onto the gingival margin regarding cytokine secreti...