Adrian Lussi

• Prof. Dr.med dent, Dipl. Chem.
• Professor at University of Bern

Objective This study aimed to examine and compare the efficacy of mouthwashes containing different proteins and peptide on the prevention of enamel erosion in vivo, as well as to evaluate the participants’ satisfaction with the formulations. Methods Twelve participants were selected and underwent five cross-over mouthwash phases: Water (control);...

Background and Objective: Limited access to health services and low educational levels are factors in the rural population that are associated with the development of oral pathologies. However, the specific risk indicators contributing to erosive tooth wear (ETW) in these populations remain unclear. The objective of this study was to identify risk...

Purpose: To investigate the prevalence and severity of erosive tooth wear (ETW) and evaluate the determinants of ETW among adolescents and adults in Poland. Materials and methods: The study covered three age groups of patients: 15 years old, 18 years old, and adults aged 35-44 years. Calibrated examiners measured ETW according to the Basic Erosi...

The aim of the present consensus paper was to provide recommendations for clinical practice on the individual etiological and modifying factors to be assessed in the individual diagnosis of caries, and the methods for their assessment, supporting personalized treatment decisions. The executive councils of the European Organisation for Caries Resear...

Introduction: This consensus paper provides recommendations for oral health professionals on why and how to assess caries activity and progression with special respect to the site of a lesion. Methods: An expert panel was nominated by the executive councils of the European Organization for Caries Research (ORCA) and the European Federation of Conse...

Background: Tooth brushing is a universal recommendation. However, the recommendations related to the time of its execution are conflicting, especially when dealing with patients at risk of erosive tooth wear (ETW) or dental caries. Summary: Our objective was to summarize the evidence on the timing of brushing with fluoridated toothpaste in rela...

The aim of the present consensus paper was to provide recommendations for clinical practice considering the use of visual examination, dental radiography and adjunct methods for primary caries detection. The executive councils of the European Organisation for Caries Research (ORCA) and the European Federation of Conservative Dentistry (EFCD) nomina...

Abstract The aims of this study were to 1) assess the association between erosive tooth wear (ETW) according to the BEWE (Basic Erosive Wear Examination) scoring system and salivary parameters and 2) compare salivary parameters according to ETW severity in the subgroup of children with ETW. This cross-sectional study included 52 preschool children...

Abstract The objective of this study was to compare the protein profile of the acquired enamel pellicle (AEP) formed in vivo in patients with or without gastroesophageal reflux disease (GERD), and with or without erosive tooth wear (ETW). Twenty-four volunteers were divided into 3 groups: 1) GERD and ETW; 2) GERD without ETW; and 3) control (withou...

Background: This study compared the performance of near-infrared light transillumination (NILT; DIAGNOcam [DC]) in detecting occlusal caries lesions in deciduous molars with the performance of the International Caries Detection and Assessment System (ICDAS), digital radiographic method (RX) and laser fluorescence (DIAGNOdent pen [LFpen]). Methods...

Background: Polyphenols interact with salivary proteins and thus can improve the pellicle's erosion protective properties. This effect could be exploited to create rinsing solutions with polyphenols as active ingredients for erosion prevention. Different from the current gold standard for erosion protective rinsing solutions, these rinses would no...

Erosiver Zahnhartsubstanzverlust wird in den letz- ten Jahren vermehrt beobachtet. Bei einer Demi- neralisation und der damit verbundenen Erwei- chung der Zahnhartsubstanz (Härteabnahme) handelt es sich um eine dentale Erosion. Sobald ein Verlust von Zahnhartsubstanz stattgefunden hat, der durch abrasive Prozesse der erweichten Ober- fläche entsteh...

Two forms of non-carious dental disorder - erosive tooth hard tissue loss and dental erosion - have been increasingly observed in recent years. Dental erosion is the chemical loss of dental hard substances caused by exposure to acids not derived from oral bacteria. Mechanical forces from, for example, the tongue, the cheeks or toothbrushing, increa...

The aim was to evaluate the effect of dissolved calcium and phosphate on dissolution rate of enamel, dentin and compressed hydroxyapatite (HA) in citric acid solution as a function of pH. At pH 2.5, dissolution rate of enamel increased significantly by 6% in 20 mmol/L added calcium but, otherwise, dissolution rates of neither enamel, dentin nor HA...

In recent decades, dentistry has developed significantly in all areas. While in the past, caries was mainly treated operatively, the today's management has shifted toward noninvasive, minimal invasive, and, only if needed, invasive treatment options. Aiming at enabling the most noninvasive or conservative treatment option requires early caries dete...

The sugarcane cystatin 5 (CaneCPI-5) showed protection against erosion and erosive tooth wear (ETW) under several protocols. However, evaluating these conditions in vivo is hard due to the lack of a suitable device. The aim of this study was to use clinically the relative surface reflection intensity (%SRI) by the Reflectometer Optipen to assess th...

Objectives: This study evaluated the protective impact of acquired enamel pellicle (AEP) engineering with statherin-derived peptide (StatpSpS), considering different AEP formation times. Design: A total of 120 native human enamel specimens were divided into 2 main groups: 1) No AEP engineering and 2) AEP engineering with StatpSpS (pretreatment f...

Propolis is increasingly being discussed as an alternative to commonly used antiseptics. This in vitro study focused on the ethanolic extract of green Brazilian propolis (EEPg) as an additive in an oral health care product. We investigated (i) a potential inflammation-modulation activity of EEPg when a periodontal or Candida biofilm was exposed to...

The objective of this study was to explore the relationship between intrinsic and extrinsic factors and a high cumulative score of the Basic Erosive Wear Examination (BEWE) in a Chilean adult group. A cross-sectional study was performed with the Ethics Committee’s approval from the Universidad de los Andes. A consecutive adult (18 to 46 years old)...

Objective: This study evaluated the preventive effect of a chitosan gel containing CaneCPI-5 against enamel erosion and erosion + abrasion in situ. Methods: Sixteen volunteers participated in a crossover, double-blind protocol, comprising 4 phases: (1) no treatment (Nt); (2) chitosan gel (Cg); (3) chitosan gel + 12,300 ppm NaF (Cg + NaF); and (4...

Objectives The aim of this study was to assess the relationship between erosive tooth wear (ETW) and possible etiological factors in a group of dental students. Materials and methods A total of 126 dental students from a public dental school were included in this study. A questionnaire was used to investigate the possible etiological factors relat...

Controversial results showing that deciduous teeth are more susceptible to erosion than permanent teeth might be related to study designs. We investigated how different conditions (pH: 3.0, 4.0, 5.0; acid agitation: gentle or vigorous; acid exposure times: 1–5 min) affect the susceptibility of both teeth to erosion. Enamel specimens (90 deciduous,...

This study evaluated the combination of a sugarcane cystatin (CaneCPI-5) and sodium fluoride (NaF) in acquired pellicle engineering for the prevention of dental erosion in vitro. 75 human enamel specimens were prepared and divided into 5 treatment groups (n = 15/group): Deionized water (Control); Elmex™ (SnCl2/NaF/AmF); 0.1 mg/ml CaneCPI-5; 500 ppm...

Aim The aim of this paper is to present recommendations from an international workshop which evaluated the methodology and reporting of caries diagnostic studies. As a unique feature, this type of studies is focused on caries lesion detection and assessment, and many of them are carried out in vitro, because of the possibility of histological valid...

Background: Specular reflection can be used to quantify dental erosion, and might also provide similar results for caries. This study assessed the possibility of using specular reflection intensity (SRI; quantitative lesion activity assessment) to measure the progression of initial enamel caries lesions. Methods: Two hundred native enamel specimens...

Die Zahnentwicklung beginnt beim menschli­ chen Embryo 28 bis 40 Tage nach der Ovula­ tion. Epitheliale Zellen wachsen in die ekto­ mesenchymalen Anteile des Kiefers. Es ent­ steht eine epitheliale Ausstülpung. Durch das weitere Eindringen der epithelialen Zellen in das Ektomesenchym wird die Zahnpapille ge­ bildet (Abb. 1, 2 und 3). Zu diesem Zeit...

Aim This systematic review and meta-analysis aimed to assess the diagnostic accuracy and reliability of commonly used caries detection methods for proximal caries diagnostics. Visual examination (VE), bitewing radiography (BWR), laser fluorescence (LF), and fibre-optic transillumination (FOTI) were considered in detail. Material and methods PRISMA...

Aim This systematic review and meta-analysis aimed to assess the diagnostic performance of commonly used methods for occlusal caries diagnostics, such as visual examination (VE), bitewing radiography (BW) and laser fluorescence (LF), in relation to their ability to detect (dentin) caries under clinical and laboratory conditions. Materials and meth...

The basic function of toothpastes is biofilm removal in order to prevent caries and gingivitis. Toothpastes should provide maximal fluoride availability, optimal abrasivity, and ingredients that do not interfere with fluoride release but should have additional beneficial effects. Further, the effect on cells of the oral cavity is of the utmost impo...

Caries diagnostic studies differ with respect to their design, included patients/tooth samples, use of diagnostic and reference methods, calibration, blinding and data reporting. Such heterogeneity makes comparisons between studies difficult and could represent a substantial risk of bias (RoB) when it is not identified. Therefore, the present repor...

Objectives: While air polishing with abrasive powders has been proved efficient for sub- and supragingival application, only few studies concerning the quality of supragingival biofilm removal using the low-abrasive erythritol powder (EP) exist. The aim of the present randomized controlled trial was to clinically compare the efficacy of supraging...

Aims To compare the dental caries prevalence using the International Caries Detection and Assessment System (ICDAS) and the caries risk by Caries Management by Risk Assessment (CAMBRA) in individuals with cerebral palsy (CP) and normoactives (NAs). Methods and results Sixty children and adolescents aged 6–12 years (30 CP/30 NA) were clinically eva...

Objective: As a preventive measure, tin (Sn2+)-containing products have a great potential to prevent enamel surface loss during erosive challenges, but adverse effects of high Sn2+ concentrations, such as astringent feeling of the teeth, are reported. Therefore, the main aim of this in vitro study was to develop a solution with lower Sn2+ concentr...

Objective This study investigated the mechanism of action of different proteins/peptides (separately or in combination), focusing on how they act directly on the native enamel surface and on modifying the salivary pellicle. Methods A total of 170 native human enamel specimens were prepared and submitted to different treatments (2 h; 37 °C): with d...

Given the importance of microorganisms in the pathogenesis of the two most prevalent oral diseases (i.e. caries and periodontitis), antiseptics are widely used. Among the antiseptics chlorhexidine (CHX) is still considered as gold standard. The purpose of this in-vitro-study was to determine the antimicrobial activity of new CHX digluconate contain...

The pH value of a biofilm influences the pathogenesis and therapy of oral diseases such as caries and periodontitis. This study aimed to investigate the influence of different initial pH values on the microbial composition, bacterial counts, metabolic activity, and quantity of three defined biofilms representing oral health, caries, and periodontal...

The formation of a physiological biofilm cannot be avoided under normal circumstances. However, the consequences of a supragingivally located biofilm, such as caries, gingivitis and, as a further effect, periodontitis, are relatively easy to avoid. The simplest and most common method used worldwide for the elimination of biofilm is periodic mechani...

Untreated dental caries is the most prevalent disease worldwide. Development of caries is associated with the intake of sugar. The microorganisms utilize the sugar and create an acidic environment, which results in mineral loss. The appropriate use of fluoride is associated with a decline of caries. Another approach in preventing caries might be th...

The goal of modern periodontal therapy, both during the initial stages and during maintenance, is to create biologically acceptable tooth surfaces through sub- and supragingival cleaning, which enables binding of the connective tissue to the greatest extent possible. In past centuries, the focus of periodontal treatment was on the removal of the su...

Aim: To provide recommendations for dental clinicians for the management of dental caries in older adults with special emphasis on root caries lesions. Methods: A consensus workshop followed by a Delphi consensus process were conducted with an expert panel nominated by ORCA, EFCD, and DGZ boards. Based on a systematic review of the literature, as...

Purpose The aim of this study was to evaluate the performance of the DIAGNOdent Pen (KaVo, Biberach, Germany) with respect to the fluorescence detection and quantification of microorganisms after the use of root canal solutions. Methods Forty roots from extracted bovine incisors were divided into four groups (n = 10) according to the contamination...

This study compared the protein profile of the acquired enamel pellicle (AEP) formed under three conditions: in vitro, in situ, and in vivo. Nine volunteers participated in all procedures. In the in vitro condition, the volunteers donated saliva, in which specimens were incubated to form the AEP. In the in situ condition, the volunteers used an ora...

Objective This study correlates the mechanical and biological response of commercially available resin-based composites (RBCs) to clinically relevant light-curing conditions. Methods Two RBCs (Venus and Venus Pearl; Kulzer) that use different monomer and photo-initiator systems, but have a similar filler volume and shade, were exposed to either ju...

Objective To investigate the modification of the salivary pellicle with different polyphenol-rich teas and natural extracts for the protection against dental erosion. Methods We performed two experiments: one with teas (Green tea, Black tea, Peppermint tea, Rosehip tea, negative control [NC]) and other with natural extracts (Grape seed, Grapefruit...

Objective: Saliva is the most important biological factor to protect against erosive tooth wear (ETW). Gastroesophageal reflux disease (GERD) patients have an increased risk of ETW due to the frequent presence of intrinsic acids in the oral cavity. Remarkably, not all GERD patients suffer from ETW, which might be due to differences in the composit...

Objectives The aim of this in vivo prospective clinical study was to validate a near-infrared light transillumination (NILT) device for the detection of proximal caries lesions and compare it to the established diagnostic method of bitewing radiography (BWR). Materials and methods A total of 116 interproximal posterior teeth/surfaces without gross...

Objectives: Biallelic variants in solute carrier family 24 member 4 (SLC24A4) have been previously reported to cause non-syndromic autosomal recessive amelogenesis imperfecta (AI) of the pigmented hypomaturation type (MIM #615887). We here describe a novel variant in SLC24A4 causing mild enamel hypomaturation defects also in heterozygous individua...

In the pedigree, one of the individuals was marked as unaffected whereas it is heterozygous for the SLC24A4 mutation.

Objectives: To provide consensus recommendations on how to intervene in the caries process in adults, specifically proximal and secondary carious lesions. Methods: Based on two systematic reviews, a consensus conference followed by an e-Delphi consensus process were held with EFCD/ORCA/DGZ delegates. Results: Managing an individual’s caries risk us...

Zusammenfassung Schmelz und Dentin bestehen zum größten Teil aus dem harten mineralischen kristallinen Material „Apatit“. Die Zahnoberfläche steht in ständigem Austausch mit ihrer Umgebung: mit dem Speichel, dem Biofilm Plaque und allem, was in den Mund hineingelangt. Dazu gehören kariogene und erosive sowie die Remineralisation fördernde Substanze...

Purpose: To evaluate the cumulative incidence and progression of erosive tooth wear (ETW) and identify risk factors over 18 months in a cohort of 11- to 14-year-old schoolchildren in Mexico. Methods: The study was conducted in public schools located in northern Mexico City. Permanent teeth of 424 schoolchildren were examined using the basic erosiv...

This paper provides recommendations for dentists for the treatment of dental caries in children, with an emphasis on early childhood caries (ECC), primary teeth, and occlusal surfaces in permanent teeth. A consensus workshop followed by an e-Delphi consensus process was conducted with an expert panel nominated by the European Organization for Carie...

Objectives To investigate the effect of toothpastes on dentine surface loss and tubule occlusion, and the association of toothpaste-related factors to each of the outcomes. Materials and methods One hundred and sixty human dentine specimens were randomly distributed into 10 groups, according to different toothpastes. The specimens were submitted t...

Background: Some studies have addressed the influence of optical magnification on the detection of caries lesions using a visual scoring system. However, there is a lack of research related to the use of the CAST and ADA-CCS visual scoring systems. In addition, the reliability and accuracy of ADA-CCS index in permanent teeth were not studied yet....

Introduction: Plant-based diets are associated with a lower: (i) body mass index, (ii) rates of death from ischemic heart disease, (iii) serum cholesterol, (iv) incidence of high blood pressure, (v) type II diabetes mellitus and cancer, with an overall longer life expectancy. However, little data concerning the oral health in individuals on a plan...

Dental erosion is the partial demineralisation of the tooth surface caused by repeated exposure to acids. The loss of surface tissue, which results from simultaneous and/or subsequent exposure to mechanical forces is known as erosive tooth wear (ETW). Excessive consumption of acidic beverages and foods has been the main focus of research into erosi...

Purpose: During biofilm formation, bacterial species do not attach directly onto the enamel surface, but rather onto the salivary pellicle. Salivary pellicle modification with casein and mucin can hinder erosive demineralisation of the enamel, but it should also not promote bacterial adhesion. The aim of our study was to assess whether salivary pe...

Objectives: To determine the prevalence, severity and distribution of erosive tooth wear lesions in adult patients at the Universidad de los Andes Health Center in the San Bernardo Metropolitan Region, Chile, during a period of 4 months in 2016. Methods: A cross-sectional study was conducted. A consecutive sample of patients from 18 to 46 years...

Background: Dental caries morbidity stages and their impact on oral health-related quality of life (OHRQoL) have not yet been established. Aim: To compare the association of dental caries morbidity stages with OHRQoL in children and adolescents from public schools of Patos-PB, Brazil. Design: A cross-sectional study was performed on 461 studen...

Die Zahnzwischenräume sind die am schwierigsten zu reinigenden Stellen im Gebiss. Neben einer erschwerten Zugänglichkeit zeichnen sich die Interdentalräume durch eine Variabilität in der Grösse und Anatomie aus. Konventionelle Zahnbürstenborsten erreichen diese Zahnflächen nur ungenügend, und die Biofilmentfernung ist unvollständig.

DIAGNOdent device emits red light from a specific laser diode that induces fluorescence of bacterial porphyrins. The intensity of caries fluorescence is correlated with the intensity of bacterial contamination, i.e., with lesion depth. DIAGNOdent has been intended to act as a second opinion device in case of questionable occlusal and proximal surfa...

Our understanding of erosive tooth wear and its contributing factors has evolved considerably over the last decades. New terms have been continuously introduced, which frequently describe the same aspects of this condition, whereas other terms are being used inappropriately. This has led to unnecessary confusion and miscommunication between patient...

DESCRIPTION A unique, multidisciplinary manual for the treatment of pediatric dental emergencies for general practitioners and non-pediatric specialists Management of Dental Emergencies in Children and Adolescents presents the diagnostic skills, treatment options, and management strategies necessary to provide effective and appropriate dental car...

The aim of this study was to evaluate the performance of Galilean and Keplerian loupes in the endodontic lumen with and without integrated light. Although the use of an operating microscope is widely recommended in endodontics it is uncertain whether an adequate loupe system with coaxial light source might replace the microscope for some endodontic...

Abstract Background There is a need for analytical techniques for measuring Erosive Tooth Wear (ETW) on natural surfaces in clinical studies. The purpose was to investigate the use of two instruments aimed to assess initial to more advanced stages of ETW. Methods Human premolar enamel samples (2x3mm) (n = 24), were polished flat and mounted in resi...

In order to better understand the therapeutic differences between deciduous and permanent teeth, one needs to be perfectly clear about the developmental and histological differences between them. This chapter aims at recapitulating the main features of tooth development: the development of enamel, dentin, and cementum. Particular attention is paid...

Objective: This study analyzed the effect of desensitizing and/or anti-erosive toothpastes on dentine permeability. Methods: One-mm dentin discs were prepared from human molars and exposed to EDTA solution (5 min, 17%). Initial dentine permeability was measured, under constant pressure. Specimens were randomly allocated into 10 groups: four anti...

There is increasing evidence that the excessive consumption of acidic drinks and foods contributes to dental erosion and may be an important contributing factor for erosive tooth wear. The aims of the present contribution were twofold: (1) to assess the erosive potential of 116 dietary substances and medications; (2) to determine the chemical prope...

«Black Stain» ist eine schwarze oder schwarz-braune, exogene Zahnverfärbung. Sie ist charakterisiert durch dunkle Linien oder Gruppen von schwarzen Punkten im zervikalen Drittel der Zahnkrone und verläuft parallel zum Gingivasaum. Es handelt sich um eine spezielle Form von stark an der Zahnoberfläche anhaftender Ablagerung (Plaque) mit erhöhter Ten...

Zahnerosionen weisen eine steigende Prävalenz auf. Aufgrund der Zerstörung kann die Lebensqualität betroffener Personen beeinflusst und Restaurationen erforderlich werden. Prophylaxe ist daher wichtig. In Beratungsgesprächen mit dem Fachpersonal kommt immer wieder die Frage nach der Erosivität verschiedener Getränke und Speisen auf, spielen sie doc...

Purpose: The effects of arginine as a toothpaste additive were assessed on oral streptococci with and without a known arginine deiminase system (ADS) and cariogenic biofilms. Materials and methods: Suspensions of Streptococcus mutans, S. sobrinus and the ADS-positive (ADS+) S. sanguinis and S. gordonii were cultured with or without 1.5% L-argini...

Aim: Drinks have different erosive potentials, but their chemical composition usually associated with erosion can be quite similar. The pellicle, and a modification thereof, might be responsible for these differences. The aim of this study was to analyze how the erosive potentials of some drinks on enamel change in the presence or absence of a pell...

Objective: This study investigated the influence of the degree of conversion (DC), resin-based composites (RBC) composition, and the effect of additional violet light from one light curing unit (LCU) on cell attachment/growth, eluate cytotoxicity, and gene expression. Methods: The effect of different DC of RBCs on human gingival fibroblasts (HGF...

Casein and mucin have been shown to improve the erosion-protective properties of the pellicle when applied in combination. The aim of this in vitro study was to optimize the concentrations of these 2 proteins to achieve a maximum protective effect. For the 2 parts of this study, we prepared a total of 195 human enamel specimens and randomly assigne...

Objective: The purpose of this in vitro study was to evaluate the antimicrobial effect of activated irrigation with different modes of erbium-doped yttrium aluminum garnet (Er:YAG) laser application on microorganisms related to secondary endodontic infection. Background: Er:YAG laser has been recommended as an adjuvant tool for root canal disinfec...

Objectives: The study evaluated the suitability of pure crystalline hydroxyapatite (HA) as a substitute for human (H) and bovine (B) enamel in erosion experiments. Methods: Human and bovine enamel and hydroxyapatite specimens (n = 18 each) were submitted to demineralisation by HCl at pH values of 3.0, 2.6 and 2.0 (1.0, 2.5, and 10 mmol/l concent...

Objective This study aimed to assess the prevalence of erosive tooth wear among 3‐ to 5‐year‐old children in Hong Kong and to determine the effect of socioeconomic factors, dental habits and oral hygiene on their dental erosive wear status. Methods Stratified random sampling was adopted. Their parents were asked to complete a questionnaire regardi...

Background Erosive tooth wear (ETW) has gained increasing clinical relevance. It is estimated that worldwide 30–50% of deciduous and 20–45% of permanent teeth are affected. One of the most important nutritional factors causing ETW is the overconsumption of soft drinks, but also patient-related factors like reflux or eating disorders can lead to ero...

Objective To assess the association between erosive tooth wear (ETW) and consumption of different kinds of beverages in a group of schoolchildren 11–14 years old in Mexico City. Methods Cross-sectional study in a sample of students (n = 512) in Mexico City. The Basic Erosive Wear Examination (BEWE) was used to quantify ETW. Beverage consumption (BC...

Aim: To evaluate the erosive preventive effect of toothpastes in permanent (PT) and deciduous teeth (dt). Design: Enamel samples were divided into five groups (n = 20): G1: placebo toothpaste; G2: NaF toothpaste; G3: AmF-NaF-SnCl2 anti-erosion toothpaste; G4: SnF2-toothpaste; and G5: NaF anti-erosion toothpaste for children. The samples were exp...

The aim of this in vitro study was to investigate the impact of saliva on the abrasion of eroded enamel using two measuring methods. A total of 80 bovine enamel specimens from 20 bovine incisors were allocated to four experimental groups (n = 20 specimens per group). After baseline surface microhardness (SMH) measurements and profilometry all speci...

Erosive tooth wear is defined as irreversible loss of dental tissues due to intrinsic or extrinsic acids, exacerbated by mechanical forces. Recent studies have suggested a higher prevalence of erosive tooth wear in males, as well as a genetic contribution to susceptibility to erosive tooth wear. Our aim was to examine erosive tooth wear by performi...

Purpose: Using the ICDAS (International Caries Detection and Assessment System), to assess caries experience in the primary dentition of preschool children living in a socioeconomically poor area with a nonfluoridated water supply, and to compare the stages of caries manifestation between children from private and public schools. Materials and me...

Objectives: This in vivo study compared the protein profile of the acquired enamel pellicle (AEP) in volunteers 1) with gastroesophageal reflux disease (GERD) and erosive tooth wear (ETW) (BEWE ≥ 9; GE group); 2) with GERD without ETW (BEWE = 0; GNE group) and 3) control (without GERD and BEWE = 0; C group). Materials and methods: Twenty-four su...

Background Little is known about fluoride toothpastes effect on deciduous teeth submitted to erosive tooth wear Objectives To evaluate the preventive effect of different toothpastes on surface loss (SL) after severe erosion/abrasion model and to compare this effect between permanent (PT) and deciduous teeth (dt). Design Enamel samples were random...

Objectives: Matrix metalloproteinases (MMPs) in dentin and saliva can degrade collagen. Divalent metals are known inhibitors of MMPs, but stannous - such as in the form of stannous chloride (SnCl2) or stannous fluoride (SnF2) - is yet to be tested for a possible inhibitory effect. In this study, we tested the inhibitory effect on the proteolytic a...

Objectives: This study aimed to assess the prevalence and severity of erosive tooth wear among 3- to 5-year-old children in Hong Kong and to determine the effect of socioeconomic factors, dental habits and oral hygiene on their dental erosion status. Methods: This survey was conducted in 2016 with ethics approval from the University of Hong Kong....