Adrián Colomer

Adrián Colomer
Universitat Politècnica de València | UPV · Institute for Research and Innovation in Bioengineering (i3B)

PhD

About

72
Publications
11,344
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470
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Introduction
Telecommunications Engineer and Master in Telecommunication Technologies, Systems and Networks since 2013 and 2014 respectively. Adrian is PhD student in the Telecommunications program and his research line focuses in the early detection of eye diseases using fundus images. He is author of several national and international publications on this field. Adrian works in ACRIMA project (TIN2013-46751-R) and his work has been supported by the Spanish Government under the FPI Grant BES-2014-067889.
Additional affiliations
May 2013 - present
May 2013 - February 2016
Universitat Politècnica de València
Position
  • PhD Student

Publications

Publications (72)
Article
Background: Embryo morphology is a predictive marker for implantation success and ultimately live births. Viability evaluation and quality grading are commonly used to select the embryo with the highest implantation potential. However, the traditional method of manual embryo assessment is time-consuming and highly susceptible to inter- and intra-ob...
Preprint
Full-text available
In this paper, we present a self-training-based framework for glaucoma grading using OCT B-scans under the presence of domain shift. Particularly, the proposed two-step learning methodology resorts to pseudo-labels generated during the first step to augment the training dataset on the target domain, which is then used to train the final target mode...
Article
Full-text available
In recent times, bladder cancer has increased significantly in terms of incidence and mortality. Currently, two subtypes are known based on tumour growth: non-muscle invasive (NMIBC) and muscle-invasive bladder cancer (MIBC). In this work, we focus on the MIBC subtype because it has the worst prognosis and can spread to adjacent organs. We present...
Article
Melanoma is an aggressive neoplasm responsible for the majority of deaths from skin cancer. Specifically, spitzoid melanocytic tumors are one of the most challenging melanocytic lesions due to their ambiguous morphological features. The gold standard for its diagnosis and prognosis is the analysis of skin biopsies. In this process, dermatopathologi...
Article
Full-text available
Glaucoma is one of the leading causes of blindness worldwide and Optical Coherence Tomography (OCT) is the quintessential imaging technique for its detection. Unlike most of the state-of-the-art studies focused on glaucoma detection, in this paper, we propose, for the first time, a novel framework for glaucoma grading using raw circumpapillary B-sc...
Article
Full-text available
Epigenetic alterations have an important role in the development of several types of cancer. Epigenetic studies generate a large amount of data, which makes it essential to develop novel models capable of dealing with large-scale data. In this work, we propose a deep embedded refined clustering method for breast cancer differentiation based on DNA...
Article
Full-text available
Atrial fibrillation (AF) is the most common cardiac arrhythmia. At present, cardiac ablation is the main treatment procedure for AF. To guide and plan this procedure, it is essential for clinicians to obtain patient-specific 3D geometrical models of the atria. For this, there is an interest in automatic image segmentation algorithms, such as deep l...
Preprint
Full-text available
Recently, bladder cancer has been significantly increased in terms of incidence and mortality. Currently, two subtypes are known based on tumour growth: non-muscle invasive (NMIBC) and muscle-invasive bladder cancer (MIBC). In this work, we focus on the MIBC subtype because it is of the worst prognosis and can spread to adjacent organs. We present...
Preprint
Glaucoma is one of the leading causes of blindness worldwide and Optical Coherence Tomography (OCT) is the quintessential imaging technique for its detection. Unlike most of the state-of-the-art studies focused on glaucoma detection, in this paper, we propose, for the first time, a novel framework for glaucoma grading using raw circumpapillary B-sc...
Preprint
Prostate cancer is one of the main diseases affecting men worldwide. The gold standard for diagnosis and prognosis is the Gleason grading system. In this process, pathologists manually analyze prostate histology slides under microscope, in a high time-consuming and subjective task. In the last years, computer-aided-diagnosis (CAD) systems have emer...
Preprint
Full-text available
The Gleason scoring system is the primary diagnostic and prognostic tool for prostate cancer. In recent years, with the development of digitisation devices, the use of computer vision techniques for the analysis of biopsies has increased. However, to the best of the authors' knowledge, the development of algorithms to automatically detect individua...
Preprint
Full-text available
Prostate cancer is one of the main diseases affecting men worldwide. The Gleason scoring system is the primary diagnostic tool for prostate cancer. This is obtained via the visual analysis of cancerous patterns in prostate biopsies performed by expert pathologists, and the aggregation of the main Gleason grades in a combined score. Computer-aided d...
Preprint
Full-text available
Prostate cancer is one of the most prevalent cancers worldwide. One of the key factors in reducing its mortality is based on early detection. The computer-aided diagnosis systems for this task are based on the glandular structural analysis in histology images. Hence, accurate gland detection and segmentation is crucial for a successful prediction....
Preprint
Full-text available
Melanoma is an aggressive neoplasm responsible for the majority of deaths from skin cancer. Specifically, spitzoid melanocytic tumors are one of the most challenging melanocytic lesions due to their ambiguous morphological features. The gold standard for its diagnosis and prognosis is the analysis of skin biopsies. In this process, dermatopathologi...
Article
Prostate cancer is one of the main diseases affecting men worldwide. The gold standard for diagnosis and prognosis is the Gleason grading system. In this process, pathologists manually analyze prostate histology slides under microscope, in a high time-consuming and subjective task. In the last years, computer-aided-diagnosis (CAD) systems have emer...
Article
Full-text available
Velocity-based training is a contemporary method used by sports coaches to prescribe the optimal loading based on the velocity of movement of a load lifted. The most employed and accurate instruments to monitor velocity are linear position transducers. Alternatively, smartphone apps compute mean velocity after each execution by manual on-screen dig...
Article
Background and Objective Prostate cancer is one of the main diseases affecting men worldwide. The Gleason scoring system is the primary diagnostic tool for prostate cancer. This is obtained via the visual analysis of cancerous patterns in prostate biopsies performed by expert pathologists, and the aggregation of the main Gleason grades in a combine...
Article
Background and objective: Optical coherence tomography (OCT) is a useful technique to monitor retinal layer state both in humans and animal models. Automated OCT analysis in rats is of great relevance to study possible toxic effect of drugs and other treatments before human trials. In this paper, two different approaches to detect the most signifi...
Article
Full-text available
Background and objective:Glaucoma is the leading cause of blindness worldwide. Many studies based on fundus image and optical coherence tomography (OCT) imaging have been developed in the literature to help ophthalmologists through artificial-intelligence techniques. Currently, 3D spectral-domain optical coherence tomography (SD-OCT) samples have b...
Chapter
Full-text available
Prostate cancer is one of the most prevalent cancers worldwide. One of the key factors in reducing its mortality is based on early detection. The computer-aided diagnosis systems for this task are based on the glandular structural analysis in histology images. Hence, accurate gland detection and segmentation is crucial for a successful prediction....
Chapter
New paradigms in aviation, as the expected shortage of qualified pilots and the increasing number of flights worldwide, present big challenges to aeronautic enterprises and regulators. In this sense, a concept known as Single Pilot Operations arises in the task of dealing with these challenges, for which, automation becomes necessary, especially in...
Article
Full-text available
Capsule endoscopy (CE) is a widely used, minimally invasive alternative to traditional endoscopy that allows visualisation of the entire small intestine. Patient preparation can help to obtain a cleaner intestine and thus better visibility in the resulting videos. However, studies on the most effective preparation method are conflicting due to the...
Chapter
Full-text available
Taking into account that glaucoma is the leading cause of blindness worldwide, we propose in this paper three different learning methodologies for glaucoma detection in order to elucidate that traditional machine-learning techniques could outperform deep-learning algorithms, especially when the image data set is small. The experiments were performe...
Preprint
Taking into account that glaucoma is the leading cause of blindness worldwide, we propose in this paper three different learning methodologies for glaucoma detection in order to elucidate that traditional machine-learning techniques could outperform deep-learning algorithms, especially when the image data set is small. The experiments were performe...
Article
Background and Objective: Prostate cancer is one of the most common diseases affecting men worldwide. The Gleason scoring system is the primary diagnostic and prognostic tool for prostate cancer. Furthermore, recent reports indicate that the presence of patterns of the Gleason scale such as the cribriform pattern may also correlate with a worse pro...
Article
Full-text available
Optical coherence tomography (OCT) is a well-established bedside imaging modality that allows analysis of skin structures in a non-invasive way. Automated OCT analysis of skin layers is of great relevance to study dermatological diseases. In this paper, an approach to detect the epidermal layer along with the follicular structures in healthy human...
Preprint
Nowadays, glaucoma is the leading cause of blindness worldwide. We propose in this paper two different deep-learning-based approaches to address glaucoma detection just from raw circumpapillary OCT images. The first one is based on the development of convolutional neural networks (CNNs) trained from scratch. The second one lies in fine-tuning some...
Preprint
Full-text available
Worldwide, prostate cancer is one of the main cancers affecting men. The final diagnosis of prostate cancer is based on the visual detection of Gleason patterns in prostate biopsy by pathologists. Computer-aided-diagnosis systems allow to delineate and classify the cancerous patterns in the tissue via computer-vision algorithms in order to support...
Article
Full-text available
Estimated blind people in the world will exceed 40 million by 2025. To develop novel algorithms based on fundus image descriptors that allow the automatic classification of retinal tissue into healthy and pathological in early stages is necessary. In this paper, we focus on one of the most common pathologies in the current society: diabetic retinop...
Chapter
Wireless Capsule Endoscopy is a technique that allows for observation of the entire gastrointestinal tract in an easy and non-invasive way. However, its greatest limitation lies in the time required to analyze the large number of images generated in each examination for diagnosis, which is about 2 h. This causes not only a high cost, but also a hig...
Chapter
The increasing use of whole slide digital scanners has led to an enormous interest in the application of machine learning techniques to detect prostate cancer using eosin and hematoxylin stained histopathological images. In this work the above problem is approached as follows: the optical density of each whole slide image is calculated and its eosi...
Article
Background and objective: Prostate cancer is one of the most common male tumors. The increasing use of whole slide digital scanners has led to an enormous interest in the application of machine learning techniques to histopathological image classification. Here we introduce a novel family of morphological descriptors which, extracted in the approp...
Article
Full-text available
Analysis of histopathological image supposes the most reliable procedure to identify prostate cancer. Most studies try to develop computer aid-systems to face the Gleason grading problem. On the contrary, we delve into the discrimination between healthy and cancerous tissues in its earliest stage, only focusing on the information contained in the a...
Article
Full-text available
Recent works show that Generative Adversarial Networks (GANs) can be successfully applied to image synthesis and semi-supervised learning, where, given a small labelled database and a large unlabelled database, the goal is to train a powerful classifier. In this paper, we trained a retinal image synthesizer and a semi-supervised learning method for...
Chapter
Full-text available
Diabetic Retinopathy (DR) is a severe and widely spread eye disease. Exudates are one of the most prevalent signs during the early stage of DR and an early detection of these lesions is vital to prevent the patient’s blindness. Hence, detection of exudates is an important diagnostic task of DR, in which computer assistance may play a major role. In...
Chapter
Full-text available
A new approach for the segmentation of gland units in histological images is proposed with the aim of contributing to the improvement of the prostate cancer diagnosis. Clustering methods on several colour spaces are applied to each sample in order to generate a binary mask of the different tissue components. From the mask of lumen candidates, the L...
Chapter
Full-text available
The performance of a Glaucoma assessment system is highly affected by the number of labelled images used during the training stage. However, labelled images are often scarce or costly to obtain. In this paper, we address the problem of synthesising retinal fundus images by training a Variational Autoencoder and an adversarial model on 2357 retinal...
Chapter
Full-text available
Regular screening for the development of diabetic retinopathy is imperative for an early diagnosis and a timely treatment, thus preventing further progression of the disease. The conventional screening techniques based on manual observation by qualified physicians can be very time consuming and prone to error. In this paper, a novel automated scree...
Conference Paper
The performance of a Glaucoma assessment system is highly affected by the number of labelled images used during the training stage. However, labelled images are often scarce or costly to obtain. In this paper, we address the problem of synthesising retinal fundus images by training a Variational Autoencoder and an adversarial model on 2357 retinal...
Article
This work investigates the characterization of bright lesions in retinal fundus images using texture analysis techniques. Exudates and drusen are evidences of retinal damage in diabetic retinopathy (DR) and age-related macular degeneration (AMD) respectively. An automatic detection of pathological tissues could make possible an early detection of t...
Chapter
Exudates are the most noticeable sign in the first stage of diabetic retinopathy. This disease causes about five percent of world blindness. Making use of retinal fundus images, exudates can be detected, which helps the early diagnosis of the pathology. In this work, a novel method for automatic hard exudate detection is presented. After an exhaust...
Article
Full-text available
The purpose of the present study is to investigate whether the effectiveness of a new ad on digital channels (YouTube) can be predicted by using neural networks and neuroscience-based metrics (brain response, heart rate variability and eye tracking). Neurophysiological records from 35 participants were exposed to 8 relevant TV Super Bowl commercial...
Conference Paper
La Degeneración Macular Asociada a la Edad (DMAE) es una enfermedad degenerativa que afecta a la mácula, estructura anatómica que se encuentra en el centro de la retina. Esta enfermedad es la principal causa de ceguera en adultos mayores de 50 años ya que la mácula es la zona del ojo encargada de la visión central. Uno de los signos más característ...
Article
Full-text available
This work focuses on finding the most discriminatory or representative features that allow to classify commercials according to negative, neutral and positive effectiveness based on the Ace Score index. For this purpose, an experiment involving forty-seven participants was carried out. In this experiment electroencephalography (EEG), electrocardiog...
Article
Some important eye diseases, like macular degeneration or diabetic retinopathy, can induce changes visible on the retina, for example as lesions. Segmentation of lesions or extraction of textural features from the fundus images are possible steps towards automatic detection of such diseases which could facilitate screening as well as provide suppor...
Conference Paper
Retinal blood vessels are considered as being interference on the retinal images for the task of detecting significant features of the most frequent eye diseases. If these blood vessel structures could be suppressed, it might lead to a more accurate segmentation of retinal lesions as well as a better extraction of textural features to be used for p...
Research
Full-text available
The main aim of this final degree project was to design and to develop a platform with modular architecture. This application allows the visualization of images obtained through Magnetic Resonance. Also this software it is provide of the main tools (filtering, change brightness and contrast, ruler to measure, creating reports, etc.) for image proce...
Research
Full-text available
This Master's thesis aims to analyse physiological signals registered in a laboratory environment during the recreation of different situations or experiences. For this purpose the performance of acquisition instruments, biosignal preprocessing, feature extraction and statistical analysis has been some of the researched topics in this work. The ov...
Conference Paper
This paper describes a new approach to identify significant points in retinal images. Significant points such as bifurcations and crossovers define and characterize the retinal vascular network. This approach is based on using hit-or-miss transformation to detect terminal, bifurcation and simple crossing points and performs a post-processing stage...
Article
This work investigates discrimination capabilities in the texture of fundus images to differentiate between pathological and healthy images. For this purpose, the performance of Local Binary Patterns (LBP) as a texture descriptor for retinal images has been explored and compared with other descriptors such as LBP filtering (LBPF) and local phase qu...
Conference Paper
This work focuses on differentiating between pathological and healthy fundus images. The goal is to distinguish between diabetic retinopathy (DR), age-related macular degeneration (AMD) and normal images by analysing the texture of the retina background. Local Binary Patterns (LBP) are used as texture descriptors. The two class problems DR vs. norm...
Conference Paper
Full-text available
This study aims to analyse the brain activity occurring during the observation of football videos randomly intermingled in a documentary. The electroencephalography recording is employed to measure the signal scalp of 20 healthy subjects. The signal preprocessing is performed using Independent Component Analysis (ICA) and ADJUST. The cerebral activ...