Adrià Rofes

Adrià Rofes
University of Groningen | RUG · Neurolinguistics and Language Development

PhD Cognitive Neuroscience, MSc Clinical Linguistics

About

54
Publications
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520
Citations
Citations since 2016
41 Research Items
501 Citations
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2016201720182019202020212022050100150

Publications

Publications (54)
Article
Full-text available
Neurosurgical mapping studies with nouns and finite verbs are scarce and subcortical data are non-existent. We used a new task that uses finite verbs in six Italian-speaking patients with gliomas in the left language-dominant hemisphere. Language-relevant positive areas were detected only with nouns in four patients, with both tasks yet in distinct...
Article
Full-text available
Background The European Low-Grade Glioma network indicated a need to better understand common practices regarding the managing of diffuse low-grade gliomas. This area has experienced great advances in recent years. Method A general survey on the managing of diffuse low grade gliomas was answered by 21 centres in 11 European countries. Here we foc...
Article
Full-text available
Multidisciplinary efforts are being made to provide surgical teams with sensitive and specific tasks for language mapping in awake surgery. Researchers and clinicians have elaborated different tasks over time. A fair amount of work has been directed to study the neurofunctional correlates of some of these tasks, and there is recent interest in thei...
Article
Full-text available
People with primary progressive aphasia (PPA) present language difficulties that require lengthy assessments and follow-ups. Despite individual differences, people with PPA are often classified into three variants that present some distinctive language difficulties.We analyzed the data of 6 fluency tasks (i.e., “F”, “A”, “S”, “Fruits”, “Animals”, “...
Article
Full-text available
Background Animal fluency is a widely used task to assess people with Alzheimer’s disease (AD) and other neurological disorders. The mechanisms that drive performance in this task are argued to rely on language and executive functions. However, there is little information regarding what specific aspects of these cognitive processes drive performanc...
Article
Full-text available
Background. People with gliomas need specialized neurosurgical, neuro-oncological, psycho-oncological, and neuropsychological care. The role of language and cognitive recovery and rehabilitation in patients’ well-being and resumption of work is crucial, but there are no clear guidelines for the ideal timing and character of assessments and interven...
Article
Full-text available
Background People with gliomas need specialized neurosurgical, neuro-oncological, psycho-oncological, and neuropsychological care. The role of language and cognitive recovery and rehabilitation in patients’ well-being and resumption of work is crucial, but there are no clear guidelines for the ideal timing and character of assessments and intervent...
Article
Introduction: People with gliomas need specialized neurosurgical, neuro-oncological, psycho-oncological, and neuropsychological care. The role of language and cognitive recovery and rehabilitation in patients’ well-being and resumption of work is crucial, but there are no clear guidelines for the ideal timing and character of assessments and interv...
Chapter
The comparison between nouns and verbs has been a topic of interest for many researchers over the last 50 years. This comparison, and subsequent behavioral and (partly) anatomic dissociation, has allowed researchers to delve into many topics including the behavioral architecture of the language system and its neural correlates, the underlying natur...
Book
Full-text available
La Prova integral d’afàsia és l’adaptació al català del Comprehensive Aphasia Test de Swinburn, Porter i Howard (2004). Es tracta d’una prova per avaluar i diagnosticar l’àfasia en catalanoparlants que s’ha desenvolupat sota la iniciativa del grup international Collaboration of Aphasia Trialists amb l’objectiu d’obtenir una eina de diagnòstic en mé...
Article
Full-text available
Introduction: Fluency tasks require language (i.e., semantics, phonological output lexicon, and phonological assembly) and executive functions (i.e., inhibition; mental set shifting; updating, and monitoring). Little is known about whether people with human immunodeficiency virus (HIV) are more impaired on a specific type of fluency task and what a...
Article
According to embodied cognition theories, concepts are represented in sensory and motor brain systems. These sensory-motor representations can give rise to priming effects. Action verbs (e.g., to push) presumably have a higher association with motor features, and sound verbs (e.g., to buzz) with auditory features. This study assesses whether motor...
Article
Full-text available
Navigated Transcranial Magnetic Stimulation (nTMS) is used to understand the cortical organization of language in preparation for the surgical removal of a brain tumor. Action naming with finite verbs can be employed for that purpose, providing additional information to object naming. However, little research has focused on the properties of the ve...
Conference Paper
Full-text available
In the present study, we combined dMRI and nTMS during an action naming task with finite verbs (Ohlerth et al., 2020) to investigate the neural underpinnings of transitive and unergative verbs. After performing fiber tracking of the left and right AF (Fekonja et al., 2019), we identified and stimulated frontal, parietal, and temporal cortical termi...
Article
Full-text available
The objective of this systematic review is to create an overview of the literature on the comparison of navigated transcranial magnetic stimulation (nTMS) as a mapping tool to the current gold standard, which is (intraoperative) direct cortical stimulation (DCS) mapping. A search in the databases of PubMed, EMBASE, and Web of Science was performed....
Article
Full-text available
Introduction Infectious agents such as viruses, bacteria, parasites, fungi, and arthropods can affect the meninges and/or the brain and trigger/relate to difficulties with language tasks. We reviewed the literature on language impairments in people with Central Nervous System (CNS) infections. Aims To review published reports of CNS infections tha...
Chapter
Intraoperative mapping of the neural processes that support noun and verb production has generally focused on naming of objects and actions. Action naming has been proposed as a good complement to object naming for intraoperative language mapping. While action naming taps into similar language functions as object naming, the processing of verbs may...
Article
Full-text available
Background: The human white matter pathway network is complex and of critical importance for functionality. Thus, learning and understanding white matter tract anatomy is important for the training of neuroscientists and neurosurgeons. The study aims to test and evaluate a new method for fiber dissection using augmented reality (AR) in a group whi...
Article
Full-text available
Healthy ageing leads to changes in the brain that impact upon sensory and cognitive processing. It is not fully clear how these changes afect the processing of everyday spoken language. Prediction is thought to play an important role in language comprehension, where information about upcoming words is pre-activated across multiple representational...
Article
Full-text available
Background: In early stages, individuals with primary progressive aphasia (PPA) report language symptoms while scoring within norm in formal language tests. Early intervention is important due to the progressive nature of the disease. Method: We report a single-case study of an individual with logopenic variant PPA (lvPPA). We tested whether letter...
Article
Full-text available
Neurosurgery has the potential to cure epilepsy but carries the risk of permanent language impairment. This risk can be estimated and minimized using Electrical Stimulation Mapping (ESM), which uses cognitive tasks and cortical stimulation to identify “eloquent” and “resectable” areas. One such task, counting, is often used to screen and characteri...
Conference Paper
Clinicians often use speech to characterize neurodegenerative disorders. Such characterizations require clinical judgment, which is subjective and can require extensive training. Quantitative Production Analysis (QPA) can be used to obtain objective quantifiable assessments of patient functioning. However, such human-based analyses of speech are co...
Preprint
Full-text available
Healthy ageing leads to changes in the brain that impact upon sensory and cognitive processing. It is not fully clear how these changes affect the processing of everyday spoken language. Prediction is thought to play an important role in language comprehension, where information about upcoming words is pre-activated across multiple representational...
Article
Predictors of treatment effects allow individual tailoring of treatment characteristics, thereby saving resources and optimizing outcomes. Electrical stimulation coupled with language intervention has shown promising results in improving language performance in individuals with Primary Progressive Aphasia (PPA). The current study aimed to identify...
Poster
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In early stages of frontotemporal degeneration, individuals who develop Primary Progressive Aphasia (PPA) complain of communication difficulties, while scoring within norm in language assessments (Czarnecki et al., 2008). Given the progressive nature of the disease, it is important to intervene early (Croot, Nickels, Laurence, & Manning, 2009). How...
Poster
Full-text available
In early stages of frontotemporal degeneration, individuals who develop Primary Progressive Aphasia (PPA) complain of communication difficulties, while scoring within norm in language assessments (Czarnecki et al., 2008). Given the progressive nature of the disease, it is important to intervene early (Croot, Nickels, Laurence, & Manning, 2009). How...
Article
Full-text available
Objective: Imaging studies in diffuse low-grade gliomas (DLGG) vary across centers. In order to establish a minimal core of imaging necessary for further investigations and clinical trials in the field of DLGG, we aimed to establish the status quo within specialized European centers. Methods: An online survey composed of 46 items was sent out to...
Article
Full-text available
Electrical Stimulation (ES) is a neurostimulation technique used to localize language functions in people with intractable epilepsy and/or brain tumors. This technique involves the application of an electrical current directly to the cortex and subcortical/axonal areas. Hence, it is an excellent method to map language functions in vivo. We reviewed...
Article
Full-text available
Background: The relationship between spontaneous speech and formal language testing in people with brain tumors (gliomas) has been rarely studied. In clinical practice, formal testing is typically used, while spontaneous speech is less often evaluated quantitatively. However, spontaneous speech is quicker to sample and may be less prone to test/ret...
Article
Full-text available
Imageability is a psycholinguistic variable that indicates how well a word gives rise to a mental image or sensory experience. Imageability ratings are used extensively in psycholinguistic, neuropsychological, and aphasiological studies. However, little formal knowledge exists about whether and how these ratings are associated between and within la...
Article
Full-text available
Comparative research on aphasia and aphasia rehabilitation is challenged by the lack of comparable assessment tools across different languages. In English, a large array of tools is available, while in most other languages, the selection is more limited. Importantly, assessment tools are often simple translations and do not take into consideration...
Poster
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The establishment of this research network is funded by the European Cooperation in Science and Technology (COST). For more information please visit www.aphasiatrials.org
Conference Paper
Full-text available
Stem-, Spraak-, en Taalpathologie
Article
Full-text available
The neurofunctional correlates of verbs and nouns have been the focus of many theoretically oriented studies. In clinical practice, however, more attention is typically paid to nouns, and the relative usefulness of tasks probing nouns and verbs is unclear. The routine administration of tasks that use verbs could be a relevant addition to current ba...
Article
Full-text available
During awake surgery, picture-naming tests are administered to identify brain structures related to language function (language mapping), and to avoid iatrogenic damage. Before and after surgery, naming tests and other neuropsychological procedures aim at charting naming abilities, and at detecting which items the subject can respond to correctly....
Article
Full-text available
Background: Castilian-Spanish, Catalan, Galician, and European Portuguese are the most widely spoken languages of the Ibero-Romance group. An increasing number of authors have addressed the impact of aphasia on the morphosyntax of these varieties. However, accurate linguistic characterisations are scarce and the different sources of data have not b...
Poster
Full-text available
Adria Rofes, Barbara Santini, Pasquale Mirtuono, Roberto Foroni, Giampietro Pinna, Lyndsey Nickels, Gabriele Miceli
Conference Paper
Full-text available
Language role of the frontal terminations of the inferior fronto-occipital fascicle in awake patient Adrià Rofes1,2, Andrea Talacchi3, Barbara Santini3, Giada Zocatelli3, Franco Alessandrini3, Lyndsey Nickels4, and Gabriele Miceli2 1. International Doctorate in Experimental and clinical Approaches to Language And the Brain (IDEALAB); 2. Center for...
Article
Full-text available
Intraoperative language mapping in awake surgery is typically conducted by asking the patient to produce automatic speech and to name objects. These tasks might not map language with sufficient accuracy, as some linguistic processes can only be triggered by tasks that use verbs and sentences. Verb and sentence processing tasks are currently used du...
Article
Full-text available
Background: Morphological errors of tense and agreement are salient in agrammatic aphasia. The PADILIH predicts impairments in discourse linking that translate to greater difficulties in referring to a past event time than to a future or a present event time. In Catalan, the Periphrastic conditional tense (e.g., “if the man had had time, he would h...

Questions

Questions (2)
Question
I wonder whether there is a meta-analysis indicating participant demographic characteristics in psycholinguistic studies. My impression is that we tend to recruit highly educated people such as students and older individuals with university degrees. However, I wonder whether anyone has looked at this in a more systematic manner, possibly revealing other biases for sex, language, etc. Thank you!
Question
Friederici (2012) reviewed the chronometry of auditory sentence processing, from auditory perception, recognition of the word form’s lexical status (word v pseudoword, 50-80ms), recognition of the word’s syntactic category, phrase structure building (120-150ms), lexical-semantic access (110-170ms), and latter sentential semantic aspects that deal with the semantic and thematic fit of the sentence (e.g., 200-400ms)
Theories of sentence processing, such as the garden-path theory (Frazier et al., 1982) indicate that we initially consider syntactic aspects, and only when those are processed, we continue with semantic processes. In a divergent manner, the constrained based theory (McDonald, 1994) indicates that all available information in a sentence can be processed at any time, hence, syntactic aspects do not necessarily need to be processed first.  
Now, if 110ms is the time when lexical-semantic access occurs at its earliest, while phrase structure building occurs at its earliest at 120ms, can this mean that in some (?rare) instances lexical-semantic access may occur before or at the same time than phrase structure building?
Refs.
Frazier, L., & Rayner, K. (1982). Making and correcting errors during sentence comprehension: Eye movements in the analysis of structurally ambiguous sentences. Cognitive psychology, 14, 178-210.
Friederici, A. D. (2012). The cortical language circuit: from auditory perception to sentence comprehension. Trends in cognitive sciences, 16(5), 262-268.
MacDonald, M. C., Pearlmutter, N. J., & Seidenberg, M. S. (1994). The lexical nature of syntactic ambiguity resolution. Psychological review, 101, 676.

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Projects

Projects (2)
Project
This project aims to investigate the level of training, awareness and knowledge of dementia, and communication disorders in dementia, and then using this information to address the anticipated lack of awareness and knowledge gaps amongst speech and language therapits (SLTs) professionals in Brazil. The project is aligned with the mission of the Global Brain Health Institute (GBHI). This project is funded by the GBHI and Alzheimer's Association.