Adeola Onakoya

Adeola Onakoya
College of Medicine University of Lagos

Professor

About

50
Publications
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457
Citations

Publications

Publications (50)
Research
Full-text available
Purpose: To explore regional variations in the presentation of newly diagnosed glaucoma in Sub Saharan Africa (SSA). Methodology: This was a multicenter, cross-sectional study in which newly diagnosed, consecutive, glaucoma patients aged older than or equal to 18 years were recruited from 27 eye clinics in 10 countries throughout SSA. Demographic a...
Article
Full-text available
Purpose: To explore regional variations in the presentation of newly diagnosed glaucoma in Sub Saharan Africa (SSA). Methodology: This was a multi-centre, cross-sectional study in which newly diagnosed, consecutive, glaucoma patients aged ≥18 years were recruited from 27 eye clinics in 10 countries throughout SSA. Demographic and ophthalmic exam...
Article
Full-text available
Purpose To determine the status of sub-specialization among Nigerian ophthalmologists as well as their dispositions and barriers against sub-specialization with a view to providing valuable information for the purpose of human resources for eye care planning thereby providing useful insight into the future of ophthalmic practice in Nigeria. Method...
Article
Background: Aim of the study was to determine the relationship between axial length (AL), keratometry and central corneal thickness (CCT), and refractive errors in adult patients attending the Guinness eye centre (GEC), Lagos university teaching hospital (LUTH) Idi-Araba, Lagos.Methods: A descriptive cross-sectional study conducted among consecutiv...
Article
Full-text available
PurposeTo compare the prevalences of diabetic retinopathy in diabetes mellitus patients, with and without primary open-angle glaucoma, with a view to determine if glaucoma is a risk factor for the development of diabetic retinopathy. Methods Cross-sectional, comparative study consisting of 86 diabetic patients with glaucoma matched with 86 diabetic...
Article
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PurposeTo correlate the clinico-cytological features of dry eye among diabetic patients attending Lagos University Teaching Hospital, Lagos.Methods This was a cross-sectional, comparative study among 104 diabetic and 104 age-/sex-matched non-diabetic participants. Demographics were obtained using interviewer-administered questionnaire. Ocular Surfa...
Article
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Background: Low vision is a very important area in Ophthalmology, however, some Ophthalmologists and eye health practitioners are not paying enogh attention to this area of ophthalmic practice. Hence, this determination of prevalence and causes of Low Vision in Kosofe Local Government Area of Lagos, South Western Nigeria. Objective: To determine th...
Article
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Background and Objective: The recent trend in cataract surgery is the use of regional ophthalmic nerve blocks or topical anesthesia. We determined and compared the effect of peribulbar and subtenon block on pain and patients' satisfaction, following small incision cataract surgery (SICS). Methods: This was age-sex-matched comparative study involvin...
Article
ABSTRACT Background: Congenital color vision defect is one of the commonest genetic defects. It affects daily and professional living. Objective: This study was conducted to determine the prevalence of color vision defects among public secondary school students in Kosofe Local Government Area, of Lagos State with a view to providing data that cou...
Article
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Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, have previously been associated with XFS. To further elucidate the genetic basis of XFS, we collected a global sample of XFS cases to refine the association at LOXL1, which previo...
Article
Full-text available
Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, have previously been associated with XFS. To further elucidate the genetic basis of XFS, we collected a global sample of XFS cases to refine the association at LOXL1, which previo...
Article
Full-text available
Purpose: To determine the subspecialty preferences of ophthalmology resident doctors in Nigeria as well as the factors influencing the choice with a view to provide useful insight into the future of ophthalmic practice in Nigeria. Materials and Methods: A descriptive, cross-sectional study was conducted among consenting ophthalmology residents in a...
Article
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Background: Presbyopia is an age-related loss of lens accommodation resulting in difficulty in performing near task with attendant effect on the quality of life. Objective: The objective of the study was to determine the prevalence of presbyopia and presbyopic spectacle correction coverage among public school teachers in Ifo township, with a view t...
Article
Objective The aim of this study was to compare intraocular pressure (IOP) measured with the Tono-Pen® to that measured using the Goldmann applanation tonometer (GAT) in patients with primary open angle glaucoma attending a glaucoma clinic. Subjects and Methods A comparative clinic-based observational study was conducted involving 75 patients (39 m...
Article
Background: There are several challenges associated with trabeculectomy and medical management in Nigeria. This makes laser trabeculoplasty a viable option in glaucoma management. This study compares Selective Laser Trabeculoplasty (SLT) with Argon Laser Trabeculoplasty (ALT) in Nigerians with open angle glaucoma. Methods: This was a retrospective...
Article
Small incision cataract surgery (SICS) offers the benefits of a phacoemulsification (phaco) surgery without the attendant high cost, but it is not without certain risk such as nucleus drop into the vitreous as seen in phaco. A retrospective study of SICS and associated factors leading to nucleus drop during surgery, challenges of management and the...
Article
Screening and early treatment of retinopathy of prematurity (ROP) is important to reduce visual impairment in at risk infants. To determine the frequency and risk factors associated with ROP in preterm infants in Lagos University Teaching Hospital. This was a prospective cohort study of preterm infants with gestational age (GA) less than 32 weeks c...
Article
Background: Glaucoma is the commonest cause of irreversible blindness in Nigeria and raised intraocular pressure (IOP) is the only modifiable risk factor. Selective laser trabeculoplasty (SLT), one of the treatment modalities, has been reported to have a cross-over effect on the fellow untreated eyes. Objectives: To determine the lOP lowering ef...
Article
Objective: To determine the pattern of presentation of uveitis at the Guinness Eye Centre of the Lagos University Teaching Hospital, Lagos, Nigeria. Materials and methods: The case files of all patients with the diagnosis of uveitis who presented at the center from January 2006 to December 2010 were reviewed. Data on age, sex, ethnicity, symptom...
Article
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To determine changes in post-cataract surgery central corneal thickness (CCT) at Lagos University Teaching Hospital by assessing the time it takes for the cornea to return to its preoperative thickness value. This study is a prospective, hospital-based open within-patient controlled study with the unoperated eye controlling for the operated one. Tw...
Article
Background: Screening and early treatment of retinopathy of prematurity (ROP) is important to reduce visual impairment in at risk infants. Aim: To determine the frequency and risk factors associated with ROP in preterm infants in Lagos University Teaching Hospital. Methods: This was a prospective cohort study of preterm infants with gestationa...
Article
Full-text available
The awareness, perceptions and experiences of Nigerian Primary Open Angle Glaucoma (POAG) patients were assessed using a hospital based cross-sectional study design. One hundred and twenty POAG patients attending a glaucoma clinic in Lagos Nigeria were recruited consecutively. They underwent face-to-face interviews with trained interviewers using a...
Article
Diabetic retinopathy is an important complication of diabetes mellitus, which may lead to blindness. The study is to analyze posterior segment lesions in Diabetes Mellitus patients seen in Guinness Eye Centre, Lagos University Teaching Hospital in relation to the number, duration and severity. All the case files of Diabetes Mellitus patients seen d...
Article
Full-text available
Knowledge of the presentation pattern of glaucoma helps in providing more understanding of the disease, leading to better control. The aim of this study was to determine the presentation pattern among newly diagnosed glaucoma patients in Lagos, Nigeria. This was a multicenter cross-sectional survey of newly diagnosed glaucoma patients, recruited ov...
Article
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To assess the current techniques of ophthalmic anesthesia in Nigeria. A cross sectional survey among Nigerian ophthalmology delegates attending the 36(th) Annual Scientific Congress of the Ophthalmology Society of Nigeria. Self administered and anonymous questionnaires were used and data were collected to include details of the institution, preferr...
Article
Conjunctival masses are growth on the surface of the outer eye; which may represent benign or malignant transformations. To determine the pattern of presentation of conjunctival masses at the Guinness Eye Centre (GEC), Lagos University Teaching Hospital (LUTH) Idi-Araba over a 13 year period (Jan 1995-Dec 2007). A retrospective review of the clinic...
Article
There is paucity of studies on the prevalence and pattern of ocular complication in HIV patients in developing countries where 90% of all HIV sufferers live. Most studies were carried out in industrialized countries and are not representative of the spectrum of ocular complication of HIV and it's prevalence in developing countries. To determine the...
Article
The eye developes from prosencephalon, the primitive forebrain and hence share similar embryonic origin with brain. This gives insight into primary or secondary involvement of eyes in intra-cranial pathology. The study was done to describe ocular findings in hydrocephalus patients and effect of intervention on the complications. Forty one consecuti...
Article
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To compare two vision-specific quality of life (QOL) instruments - the disease-specific 15-item Glaucoma Quality of Life questionnaire (GQL-15) and the nonglaucoma-specific 25-item National Eye Institute Visual Function Questionnaire (NEIVFQ25). The QOL of 132 glaucoma patients being managed in Lagos University Teaching Hospital and an equal number...
Article
Purpose: To estimate the outpatient clinic burden and surgical workload related to glaucoma in Lagos, Nigeria. Methods: A multicentre study involving the 2 tertiary eye institutions, 7 secondary eye centers with eye care facilities, and the largest private eye hospital in Lagos state, Nigeria. Data on outpatient department (OPD) visits were coll...
Article
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Purpose: To describe the frequency, causes and Visual Outcome of ocular trauma seen in Lagos University Teaching Hospital (LUTH), Lagos. Study Design: A retrospective study. Methods: The case records of patients referred to Guinness Eye Center in LUTH, with ocular trauma during the last 4 years were reviewed. The age and gender of patients, type...
Data
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Background: Glaucoma is a common cause of blindness. Particularly in West Africa where most affected patients present late in the clinic, glaucoma is often associated with psychological complications with possible effect on quality of life. Methods: The study was carried out in the glaucoma clinic of Lagos University Teaching Hospital on consenting...
Article
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ENGLISH/ ABSTRACT [ENGLISH/ ABSTRACT [ENGLISH/ ABSTRACT [ENGLISH/ANGLAIS ANGLAIS ANGLAIS ANGLAIS] ] ] ] Affiliations: Inconsistent relationship exists between plasma homocysteine (Hcy), an "emerging" atherosclerotic risk factor and other traditional atherosclerotic risk factors. Previous studies have chiefly originated from the industrialised West,...
Article
To evaluate the quality of life (QOL) of primary open angle glaucoma (POAG) patients attending a tertiary eye institution in Lagos, Nigeria and identify clinical and sociodemographic factors affecting it. A hospital-based cross-sectional analytical study design was used to compare 132 patients with varying degrees of severity of glaucoma (cases) wi...
Article
The Vitreous Humour is the transparent biological gel which fills the posterior 5/6th of the eyeball. Extravasations of blood into this delicate tissue may cause visual loss. The study was to determine the causes and pattern of vitreous haemorrhage in Guinness eye centre, Lagos University Teaching Hospital. Retrospective consecutive case series of...
Article
To collate the self-reported assessment of familiarity with some aspects of managerial competencies on the part of some surgeons and their observations on the managerial environment of their health institutions and draw appropriate policy implications. Cross-sectional study using a structured questionnaire. The study was conducted during the 50th A...
Article
Vernal keratoconjunctivitis (VKC) (Spring Catarrh) is a chronic, seasonally exacerbated bilateral external allergic ocular inflammation which causes a lot of ocular discomfort to children and young adults and, in severe or poorly managed cases, can even lead to blindness. To determine age/sex distribution, seasonal pattern, and frequency of clinica...
Article
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Marfan's syndrome is a connective tissue disorder inherited as an autosomal dominant disorder. It causes a myriad of distinct clinical problems, of which the musculoskeletal, cardiac, and ocular system problems predominate. Nearly 50 percent of patients have to undergo aortic surgery in their lifetime resulting in reconstruction or replacement of t...
Article
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To investigate the association between Primary Open Angle Glaucoma (POAG), Intraocular Pressure (IOP) and systemic hypertension. Cross-sectional, convenient and controlled study. Eye Clinic of the Lagos University Teaching hospital, Idi-Araba, Lagos, Nigeria. Consecutive newpatients with documented history of hypertension medication of over three m...
Article
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To determine the influence of the use of central nervous system (CNS) stimulants on visual functions and occurrence of road traffic accidents (RTA) amongst commercial drivers. A cross-sectional study in which two hundred and fifteen consecutive drivers were interviewed and their eyes examined. Ife Central Local Government Area (LGA) of Osun State,...
Article
Objectives: To compare the pharmacodynamic activities of Garcinia Kola nut (GK) extract with known antiglaucoma medication using the movements and sites of separation on thin layer chromatography. Study Design: Experimental Study Materials and Methods: Garcinia kolanuts were obtained from Ogun state. Drugs in comparison were 0.5% Betaxolol, 0.5%...
Article
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Objective: To determine the commonest post-operative complications of cataract surgery seen at LUTH over a 5year period. Methodology: All case notes and operation notes of patients who have had cataract surgery over a period of 5years [Jan'98-Dec'02] were retrospectively studied and analyzed. Results: A total of 272 eyes in 254 patients were operat...
Article
To determine the commonest type of ocular emergencies seen at L.U.T.H. over a period of one year. Data of all consecutive patients seen as emergencies within the designated period was taken. These included age, sex, symptoms, signs, agents of injury, duration and the complications. A total of 304 patients were seen. 207 (68.0%) of them were males,...
Article
To determine the effects of the visual functions on the occurrence of road traffic accidents (RTA) amongst commercial drivers in Ife central local government area (LGA) of Osun state of Nigeria. A cross-sectional study. Four major motor parks located at Ife Central LGA. Of the estimated 270 commercial drivers in the four major parks of the LGA, 215...
Article
To ascertain the efficacy of Lodoxamide 0.1 in the reduction of Clinicopathological signs of the conjunctiva in Vernal Keratoconjunctivitis. Prospective, non-comparative, Convenient Interventional Case Series. One Hundred consecutive patients; 57 males and 43 females within age range 2-55 years diagnosed with active and untreated Vernal conjunctivi...
Article
Objective : To study the pattern of normal intraocular pressure (IOP) in Lagos, Nigeria. Study Design : Prospective non-randomized uncontrolled hospital-based study. Methodology : Consecutive new patients coming into three different eye clinics between June and August 2001 had their IOP measured by applanation. The demographic characteristics and l...
Article
Twenty-eight eyes of 26 age-matched patients who had planned extracapsular cataract extraction with or without intraocular lens implantation were enrolled into a double blind randomised actively controlled study of 2 groups. Each group of 14 eyes was assigned to receive 0.1% diclofenac sodium (Naclof) eye drops or 1% prednisolone acetate eye suspen...

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