Adel Salah Bediwy

Adel Salah Bediwy
Tanta University · Department of Chest and Heart Surgery

Professor

About

68
Publications
14,855
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
648
Citations
Introduction
Prof. Adel Salah Bediwy currently works as a professor of Chest Diseases at Chest Department, Faculty of Medicine, Tanta University and Consultant of Pulmonolgy at Tanta University Hospital, Egypt. He does researches in Pulmonology, and Sleep Medicine. The current projects are about lung cancer, bronchial asthma, sleep medicine, ILD, respiratory infections, interventional pulmonology, pleural diseases, and COPD.
Additional affiliations
July 2017 - present
Tanta University
Position
  • Professor
July 2012 - July 2017
Tanta University
Position
  • Professor

Publications

Publications (68)
Article
Full-text available
BACKGROUND The relationship between diabetes mellitus (DM) and asthma is complex and can impact disease trajectories. AIM To explore the bidirectional influences between the two conditions on clinical outcomes and disease control. METHODS We systematically reviewed the literature on the relationship between DM and asthma, focusing on their impact...
Article
Full-text available
BACKGROUND Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by heterogeneous symptoms and genetic underpinnings. Recent advancements in genetic and epigenetic research have provided insights into the intricate mechanisms contributing to ASD, influencing both diagnosis and therapeutic strategies. AIM To explore...
Article
Full-text available
BACKGROUND Pulse oximetry has become a cornerstone technology in healthcare, providing non-invasive monitoring of oxygen saturation levels and pulse rate. Despite its widespread use, the technology has inherent limitations and challenges that must be addressed to ensure accurate and reliable patient care. AIM To comprehensively evaluate the advant...
Article
Full-text available
BACKGROUND Fecal calprotectin is a valuable biomarker for assessing intestinal inflammation in pediatric gastrointestinal diseases. However, its role, pros, and cons in various conditions must be comprehensively elucidated. AIM To explore the role of fecal calprotectin in pediatric gastrointestinal diseases, including its advantages and limitation...
Article
Full-text available
BACKGROUND Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficits in social communication and repetitive behaviors. Metabolomic profiling has emerged as a valuable tool for understanding the underlying metabolic dysregulations associated with ASD. AIM To comprehensively explore metabolomic changes in children wi...
Article
Full-text available
Microphallus/Micropenis is a rare condition with significant physical and psychological implications for affected individuals. This article comprehensively reviews micropenis, its etiology, epidemiology, and various treatment options. We conducted a thorough literature review to collect relevant information on micropenis and microphallus, as well a...
Article
Full-text available
BACKGROUND Infants' nutrition significantly influences their growth, development, and overall well-being. With the increasing demand for organic infant formula driven by the perception of health benefits and growing awareness of natural feeding options, it is crucial to conduct a comparative analysis of the gastrointestinal tolerability between org...
Article
Full-text available
Renal tubular acidosis (RTA) can lead to renal calcification in children, which can cause various complications and impair renal function. This review provides pediatricians with a comprehensive understanding of the relationship between RTA and renal calcification, highlighting essential aspects for clinical management. The article analyzed relevan...
Article
Full-text available
Investigating gastrointestinal (GI) motility disorders relies on diagnostic tools to assess muscular contractions, peristalsis propagation and the integrity and coordination of various sphincters. Manometries are the gold standard to study the GI motor function but it is increasingly acknowledged that manometries do not provide a complete picture i...
Article
Full-text available
BACKGROUND It is common for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to occur in the gastrointestinal tract, which can present itself as an initial symptom. The severity of coronavirus disease 2019 (COVID-19) is often reflected in the prevalence of gastrointestinal symptoms. COVID-19 can damage the nerve supply to the...
Article
Full-text available
Background: It is common for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to occur in the gastrointestinal tract, which can present itself as an initial symptom. The severity of coronavirus disease 2019 (COVID-19) is often reflected in the prevalence of gastrointestinal symptoms. COVID-19 can damage the nerve supply to th...
Article
Full-text available
Grade A (Excellent): 0 Grade B (Very good): B Grade C (Good): C Grade D (Fair): 0 Grade E (Poor): 0 P-Reviewer: Masaru T, Hungary; Masyeni S, Indonesia Abstract Autism spectrum disorder (ASD) is a group of heterogeneous, multi-factorial, neurodevelopmental disorders resulting from genetic and environmental factors interplay. Infection is a signific...
Article
Full-text available
Background: Breast milk is the best and principal nutritional source for neonates and infants. It may protect infants against many metabolic diseases, predominantly obesity and type 2 diabetes. Diabetes mellitus (DM) is a chronic metabolic and microvascular disease that affects all the body systems and all ages from intrauterine life to late adult...
Article
Full-text available
There has been an increasing number of reported cases of acute hepatitis of unknown origin in previously healthy children since first reported on March 31, 2022. This clinical syndrome is identified by jaundice and markedly elevated liver enzymes with increased aspartate transaminase and/or alanine aminotransaminase (greater than 500 IU/L). We cond...
Article
Full-text available
Pleural effusion usually causes a diagnostic dilemma with a long list of differential diagnoses. Many studies found a high prevalence of pleural effusions in critically ill and mechanically ventilated patients, with a wide range of variable prevalence rates of up to 50%-60% in some studies. This review emphasizes the importance of pleural effusion...
Article
Full-text available
The coronavirus disease 2019 (COVID-19) pandemic affects all countries and populations worldwide, significantly impacting people with autism with a high risk of morbidity and mortality due to COVID-19. Approximately 25% of children with autism have an asymptomatic or symptomatic immune deficiency or dysfunction. In addition, they frequently have va...
Article
Full-text available
Milk is related to many gastrointestinal disorders from the cradle to the grave due to the many milk ingredients that can trigger gastrointestinal discomfort and disorders. Cow's milk protein allergy (CMPA) is the most common food allergy, especially in infancy and childhood, which may persist into adulthood. There are three main types of CMPA; imm...
Article
Full-text available
BACKGROUND Insulin pump therapy is a real breakthrough in managing diabetes Mellitus, particularly in children. It can deliver a tiny amount of insulin and decreases the need for frequent needle injections. It also helps to maintain adequate and optimal glycemic control to reduce the risk of metabolic derangements in different tissues. Children are...
Article
Full-text available
Coronavirus disease 2019 (COVID-19) is a real challenge for humanity with high morbidity and mortality. Despite being primarily a respiratory illness, COVID-19 can affect nearly every human body tissue, causing many diseases. After viral infection, the immune system can recognize the viral antigens presented by the immune cells. This immune respons...
Article
Full-text available
Gut microbiota has a significant role in gut development, maturation, and immune system differentiation. It exerts considerable effects on the child's physical and mental development. The gut microbiota composition and structure depend on many host and microbial factors. The host factors include age, genetic pool, general health, dietary factors, m...
Article
Full-text available
Cough is a common respiratory complaint driving patients to seek medical advice. Besides being a fundamental respiratory sign, it is also a crucial neurological sign. There are three main types of coughs: Reflex cough (type I), voluntary cough (type II), and evoked cough (type III). Cough is a reflex predominantly mediated by control centers in the...
Article
Full-text available
Initial data suggest that insulin resistance (IR) is becoming more common in children and adolescents than before. IR is insulin failure in the normal plasma levels to adequately stimulate glucose uptake by the peripheral tissues such as adipose tissues and skeletal muscle, inhibit the hepatic gluconeogenesis and release of glucose into circulation...
Article
Full-text available
For many years, ultrasound was thought to have no indications in pulmonary imaging because lungs are filled with air, creating no acoustic mismatch, as encountered by ultrasound wave beam. Lung ultrasound (LUS) was started in adult critical care settings to detect pleural effusion and acquired more indications over time. In the neonatal intensive c...
Article
Full-text available
Coronavirus Disease 2019 (COVID-19) is a major challenge for health systems worldwide. Molecular diagnosis is a cornerstone in the management of COVID-19. Clinicians should understand the various aspects of molecular testing that may influence their judgment and management. Cycle threshold, viral shedding, and recurrence are among the most common a...
Article
Full-text available
impaired pulmonary function test. There are no studies that correlated the degree of impaired pulmonary function in children with SCD with the degree of impairment of their quality of life. Besides, it is very challenging to segregate the effect of SCD on the child's quality of life from impaired pulmonary function. Hence more studies are needed. A...
Article
Full-text available
The coronavirus disease 2019 (COVID-19) pandemic is a threat worldwide for individuals of all ages, including children. Gastrointestinal manifestations could be the initial presenting manifestation in many patients, especially in children. These symptoms are more common in patients with severe disease than in patients with non-severe disease. Appro...
Preprint
Full-text available
Cough is one of the most common complaints that lead patients to see a doctor. It is not only a basic respiratory sign but also an important neurological sign. There are 3 main types of cough: reflex cough (type I), voluntary cough (type II), and evoked cough (type III). Reflex cough sensitivity may be increased in many neurological disorders, such...
Article
Full-text available
Background Cancer development is associated with deregulated microRNA (miRNA) in body fluids including serum, plasma, and bronchoalveolar lavage (BAL). Early diagnosis and early treatment of lung cancer improve survival and response to treatment. So, finding an easy detectable biomarker is crucially important to improve the disease outcome. So, we...
Article
Background Sickle cell disease (SCD) is relatively common in Bahrain, and airway inflammation in patients with SCD is usually multifactorial. This study aimed to evaluate lung function and induced sputum levels of interleukin (IL)‐6 in Bahraini children and adolescents with SCD and asses their relationship with the recurrence of acute chest syndrom...
Article
Full-text available
Background: EBUS-TBNA represents a new technology in the field of bronchoscopy The primary indications for EBUS-TBNA are staging NSCLC and the diagnostic assessment of mediastinal lymphadenopathy. EBUS-TBNA also has a diagnostic role in suspected benign disease, especially sarcoidosis and tuberculosis. It is a minimally invasive option as the first...
Article
Full-text available
Background Asymmetric dimethylarginine (ADMA) is a new marker of inflammation in different inflammatory disorders. Bronchial asthma as a chronic disease of inflammatory nature is related to an expanded levels of numerous markers of inflammation which are used to assess the degree of severity of childhood asthma and might be the object of new therap...
Article
Full-text available
Abstract Introduction Rapid on-site evaluation (ROSE) is a technique used for immediate interpretation of transbronchial aspirates; there is debate as regards the contribution of ROSE to the diagnostic or staging process in patients with lung cancer undergoing endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Aim of the...
Article
Full-text available
Abstract Background Hypoxemia is the most serious threat to organ function. Therefore, the goal is to reverse tissue hypoxia. The aim of this study was to compare heated and humidified high-flow nasal cannula (HFNC) with conventional low-flow nasal cannula (LFNC) oxygen therapy in acute hypoxemic respiratory failure (RF). Patients and methods This...
Article
Full-text available
Abstract Background Endobronchial ultrasound (EBUS) has become a powerful tool for the diagnosis of mediastinal and hilar lymph nodes (LNs). Elastography has been introduced recently to provide more accurate data about the lesions seen during EBUS. Aim The aim of this study was to evaluate the role of elastography during EBUS for the diagnosis of h...
Article
Full-text available
Background: Receptor of advanced glycation end products (RAGE) is a new marker of inflammation in different inflammatory disorders. Bronchial asthma as an inflammatory disease is associated with increased levels of many markers of inflammation which are used to evaluate the severity of childhood asthma, and may be the targets of new therapeutic opt...
Article
Full-text available
and Aims . Treatment of hepatic hydrothorax is a clinical challenge. Chest tube insertion for hepatic hydrothorax is associated with high complication rates. We assessed the use of pigtail catheter as a safe and practical method for treatment of recurrent hepatic hydrothorax as it had not been assessed before in a large series of patients. Methods...
Article
Full-text available
Abstract Background Pulmonary tuberculosis (TB) sometimes has diagnostic difficulties and a lot of differential diagnosis such as pneumonia. The aim of this work was to assess the role of serum neopterin in differentiating between pulmonary TB and pneumonia and to estimate the effect of antituberculous drugs for 2 months on serum levels of neopteri...
Article
Full-text available
Background: Receptor of advanced glycation end products (RAGE) is a new marker of inflammation in different inflammatory disorders. Bronchial asthma as an inflammatory disease is associated with increased levels of many markers of inflammation which are used to evaluate the severity of childhood asthma, and may be the targets of new therapeutic opt...
Article
Full-text available
Background: Metabolic syndrome is a medical disorder that predisposes to cardiovascular diseases. Excessive daytime sleepiness (EDS) is a common finding in patients with metabolic syndrome. Aim: To assess the presence of EDS among subjects with metabolic syndrome and to find its correlations with apnea hypopnea index (AHI), Hamilton depression rati...
Article
Full-text available
Background and objective Multidetector CT (MDCT) and ultrasonography (US) are of increasing importance for assessment of many pulmonary disorders. Our aim was to evaluate their role in diagnosis of pleural diseases. Methods Patients from Tanta University Hospital who were suspected to have pleural lesions (symptoms, signs and/or suggestive chest X...
Article
Full-text available
Pancreatico-pleural fistula is a rare entity and it accounts for a small percentage of cases of pleural effusion. We present a case of massive right sided pleural effusion that was attributable to pancreatico-pleural fistula in a 46 year old male alcoholic patient who had dyspnea, trepopnea and dull aching right sided chest pain. ERCP showed a fist...
Article
Full-text available
Background Children with nocturnal enuresis (NE) are believed to have deep sleep with high arousal threshold. Studies suggest that obstructive sleep apnea–hypopnea syndrome (OSAHS) and NE are common problems during childhood. We sought to assess the prevalence of OSAHS in children with refractory NE and whether its severity is associated with the f...
Article
Full-text available
Gastroesophageal reflux (GER) is a common disorder in children with bronchial asthma. It has been identified as a potential trigger, complication and even differential diagnosis for asthma. Our aim was to find out the efficacy of the combined use of both the proton pump inhibitor esomeprazole and the antidopaminergic prokinetic domperidone versus t...
Conference Paper
The objective. was to investigate L-Carnitine level and the effects of its supplementation in children with moderate persistent Asthma. Methods. Free and total serum carnitine levels were measured in 50 children having moderate persistent asthma and 50 healthy control children. The patients group was randomly divided into two subgroups. Subgroup A...
Article
Full-text available
Background: Children with nocturnal enuresis (NE) are believed to have deep sleep with high arousal threshold. Studies suggested that obstructive sleep apnoea-hypopnoea syndrome (OSAHS) and NE are common problems during childhood. We sought to asses the prevalence of OSAHS in children with refractory nocturnal enuresis and whether its severity is a...
Article
Full-text available
Background and Objectives: Gastroesophageal reflux (GER) is a common finding in asthmatic children and has been identified as a potential trigger for asthma. The aim of this study was to investigate the efficacy of combined use of both esomeprazole and antidopaminergic prokinetic domperidone versus the sole use of esomeprazole in improving asthma s...
Article
Background: Obstructive sleep apnea (OSA) is associated with depression, anxiety, and cognitive impairment that can be improved with treatment. Objectives: To assess depression, anxiety, and executive functions in patients with OSA before and after treatment with continuous positive airway pressure (CPAP). Participants and methods: Twenty patients...
Article
Full-text available
The objective. was to investigate L-Carnitine level and the effects of its supplementation in children with moderate persistent Asthma. Methods. Free and total serum carnitine levels were measured in 50 children having moderate persistent asthma and 50 healthy control children. The patients group was randomly divided into two subgroups. Subgroup A...
Conference Paper
Full-text available
Objectives. To assess the induced sputum substance P (ISSP) levels in children having difficult-to-treat asthma (DA) with and without gastroesophageal reflux (GER). We aimed also to evaluate the association of GER with childhood DA, relationship of GER severity with childhood asthma control test (C-ACT), FEV1, peak expiratory flow (PEF) variability...
Article
Background: Obstructive sleep apnea (OSA) is a relatively common disorder which has a negative impact on the psychological well-being of affected individuals. Objective: To assess the association between OSA and depression as well as the effect of treatment with continuous positive airway pressure (CPAP). Methods: A total of 37 newly diagnosed in...
Article
Full-text available
Objectives. To assess the induced sputum substance P (ISSP) levels in children having difficult-to-treat asthma (DA) with and without gastroesophageal reflux (GER). We aimed also to evaluate the association of GER with childhood DA, relationship of GER severity with childhood asthma control test (C-ACT), FEV1, peak expiratory flow (PEF) variability...
Article
Full-text available
Objectives: Gastroesophageal reflux (GER) is a common in asthmatic children and was identified as a trigger for asthma. We aimed to investigate efficacy of use of esomeprazole-domperidone combination versus using only esomeprazole in improving asthma severity in children with difficult to treat asthma. Patients and Methods: Our study included 89 ch...
Article
Full-text available
Background. Use of small-bore pigtail catheter is a less invasive way for draining pleural effusions than chest tube thoracostomy. Methods. Prospectively, we evaluated efficacy and safety of pigtail catheter (8.5–14 French) insertion in 51 cases of pleural effusion of various etiologies. Malignant effusion cases had pleurodesis done through the cat...
Article
Full-text available
Obstructive sleep apnea (OSA) is a relatively common disorder which has a negative impact on the psychological well-being of affected individuals. To assess the association between OSA and depression as well as the effect of treatment with continuous positive airway pressure (CPAP). A total of 37 newly diagnosed individuals with OSA underwent an ov...
Data
The objective. was to investigate L-Carnitine level and the effects of its supplementation in children with moderate persistent Asthma. Methods. Free and total serum carnitine levels were measured in 50 children having moderate persistent asthma and 50 healthy control children. The patients group was randomly divided into two subgroups. Subgroup A...
Article
Sickle cell disease (SCD) is a common genetic disorder of hemoglobin in Bahrain with a lot of pulmonary complications either acute or chronic including its effect on pulmonary function tests (PFT). IL-6 is an inflammatory cytokine that was found to be high in serum of SCD patients. Objective: To study PFT and evaluate BAL IL-6 level in adult Bahra...
Chapter
Full-text available
The lung may act as an endocrine gland secreting certain hormones or substances that can affect heart functions forming what is known as humoral heart–lung interaction. The lung helps in deactivation of 5-hydroxytryptmine, acetylcholine, norepinephrine, bradykinin and prostaglandins E1, E2 and F2. It produces angiotensin converting enzyme that help...
Article
Full-text available
Objectives. To assess the induced sputum substance P (ISSP) levels in children having difficult-to-treat asthma (DA) with and without gastroesophageal reflux (GER). We aimed also to evaluate the association of GER with childhood DA, relationship of GER severity with childhood asthma control test (C-ACT), FEV(1), peak expiratory flow (PEF) variabili...
Article
Full-text available
Background. Soluble triggering receptor expressed on myeoid cells-1 (sTREM-1) has recently been found to be high in infected pleural fluid (PF). Objectives. Diagnostic accuracy of PF sTREM-1 for differentiating uncomplicated parapneumonic effusions (UPPEs) from complicated parapneumonic effusions (CPPEs) was evaluated prospectively. Methods. Serum...

Network

Cited By