Additiya Paramanya

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• PhD
• Professor (Assistant) at Ramnarain Ruia College

This study provided a thorough evaluation of a Spirulina platensis extract-infused cream, assessing its physical properties, stability, microbial safety, spreadability, irritancy, moisture retention, and bioactive potential. The cream exhibited highly desirable attributes, making it a promising candidate for cosmetics, meeting industry standards. I...

Polysaccharides are one of the most abundantly occurring macromolecules. Their practical uses run through a much broader spectrum. With many engaging and noteworthy properties of polysaccharides, these molecules have many medical applications and have a wide array of biological functions. In this context, polysaccharides have also been studied for...

Glycation, a non-enzymatic interaction between the carbonyl groups of sugars and the amino groups of macromolecules, leads to the formation of deleterious advanced glycation end-products (AGEs). Diseases such as neurodegenerative disorders, cardiovascular complications, and diabetes are characterized by the involvement of glycated products. This st...

Glucose, the predominant carbohydrate in the human body, initiates nonenzymatic reactions in hyperglycemia, potentially leading to adverse biochemical interactions. This study investigates the interaction between glucose and Bovine Serum Albumin (BSA), along with the protective effects of Spirulina platensis PCC 7345 aqueous extract. Phycobiliprote...

Background and Objectives Phycocyanin, a water-soluble blue pigment extracted from cyanobacteria, is used in various industries. Research has explored its health benefits like antioxidants and anti-inflammatory properties. However, challenges remain in extracting it efficiently and ensuring stability. This study employs a Quality by Design (QbD) ap...

The discovery of antibiotics saved many lives. Infections were not as deadly a problem for clinicians as they once were. However, due to inappropriate and excessive use of antibiotics, antibiotic resistance has increased dramatically worldwide. Infectious diseases are becoming more challenging to control, and they cause increased morbidity and mort...

The discovery of antibiotics saved many lives. Infections were not as deadly a problem for clinicians as they once were. However, due to inappropriate and excessive use of antibiotics, antibiotic resistance has increased dramatically worldwide. Infectious diseases are becoming more challenging to control, and they cause increased morbidity and mort...

Human race has been using plants and cyanobacteria for thousands of years for various purposes like food, feed, and medicines. One of them is Spirulina, a powdered form of multicellular organism’s biomass belonging to the family of cyanobacteria, which is used as food in many countries since centuries. The organisms required to produce spirulina ca...

Background Spirulina ( Arthrospira platensis), a cyanobacterium, is being consumed worldwide owing to its high nutritional value and therapeutic potential. Objectives This study aims to determine the phytochemical content, antioxidant capacity, and antiglycation property of A. platensis PCC 7345 aqueous extract against glucose, fructose, and ribos...

Bee products, including honey, have been utilized since ancient times for nutritional and therapeutic purposes. Recently, other bee products such as bee pollen, royal jelly, and propolis have caught a lot of attention. Being high in antioxidants and bioactive compounds, these products have established their applications in the pharmaceutical field...

Diabetes has become a major metabolic disorder in the last few decades. It is manifested as dysregulation of glucose metabolism at one of the steps involving transport, absorption, and metabolic regulation by insulin. Changes in lifestyle and food consumption habits have also increased the number of people with diabetes. Some physicians prescribe s...

Microorganism-based bioremediation is a well-sought after method for industrial wastewater treatment and forms the primary stage. The current research suggests using Spirulina platensis as an organism of choice for bioremediation. This study provides an insight into the potential use of primary-treated wastewater as the growth media for Spirulina p...

Polycystic ovarian syndrome (PCOS) is one of the prevailing endocrine disorders causing reproductive as well as metabolic dysfunctions in women. First described by Stein and Leventhal in 1935, as a condition where approximately 10 small cysts (∼2 and 9 mm diameter) on one or both ovaries and/or the ovarian volume exceeds 10 ml of at least one ovary...

Excessive generation of wastewater is one of the major reasons for pollution in natural reservoirs. Given the normal circumstances, natural water bodies revive and rejuvenate themselves; but upon increased waste load, the self-revival system of the ecosystem slows down, causing water pollution. Hazardous waste, especially heavy metals and organi...

Polycystic ovarian syndrome (PCOS) is one of the most common endocrine and reproductive disorders observed in women. Its pathophysiology indicates its involvement in plenitude of diseases and/ or disorders. Although the absolute cause of PCOS has not been established, its prevalence in diabetic patients is noteworthy. Glycation and insulin resistan...

Coronaviruses usually target and affect the respiratory tracts of birds and mammals. In humans, the coronaviruses can cause respiratory infections ranging from a simple common cold to serious infections causing severe acute respiratory illness, including fever, cough, and shortness of breath. A ‘once-in-a-century pandemic’ i.e. COVID-19 started wit...

Secondary metabolites (SMs) are the nonessential compounds synthesized by plants that help them to combat stressed conditions. Being sessile, plants produce SMs to maintain the integrity of the cellular structure and perform functions required for their growth and development in extreme environments. They carry out a multitude of functions ranging...

(Medicinal and aromatic plants (MAPs) are important sources of herbal medicine. Despite their vast potential in the medicinal and pharmaceutical fields, most of them have not been used to their optimum. Nanotechnology, a science at nanoscale, has emerged as a promising tool in the MAPs research and has established its wide application in therapeuti...

Obesity is one of the common metabolic diseases which is tremendously on the rise. According to the World Health Organization (WHO), the number of patients has increased three times since 1975. A person with Body Mass Index (BMI) equal to or higher than 30.0 is considered obese. Previously considered only as a cosmetic concern, obesity has now been...

Oxidative stress is a phenomenon wherein there is an imbalance between the rate of oxidant formation and its elimination from the body. It has been known to be a promoting factor of various acute and chronic diseases, some of which are lethal. Oxidative stress usually occurs when the generation of oxidants, as a byproduct of the metabolic processes...

Spirulina (Arthrospira) sp. is a genus of free-floating, multicellular cyanobacteria which have find its application as a dietary supplement or whole food for humans as well as other species. It consists of two species namely, S. platensis and S. maxima. Typically available in its dried form, 100 gm of Spirulina powder contains several essential nu...

Plants are the primary sources for most of the food items for all organisms. Human beings have also used plants for purposes other than food, for example, for making tools and houses as well as medicine. Most of the civilizations have a rich history of traditional medicine based on plant extracts or preparations. In last few centuries, the active c...

Diabetes has become a dangerous health threat and a socio-economic problem for the world. Change in the lifestyle and food habits have added to the increasing list of causative factors of diabetes. Hyperglycemia is used as the marker for identification of this disorder. This causes the generation of a group of harmful products commonly known as adv...