Adang Bachtiar

University of Indonesia | UI · Health Administration and Policy

Latar belakang: Sebagai hasil dari persaingan yang semakin meningkat yang ada dalam ekonomi pada skala dunia, institusi kesehatan, serta rumah sakit khususnya, menempatkan penekanan yang lebih besar pada pemenuhan atau melampaui persyaratan pelanggan mereka. Disebabkan oleh rumah sakit ini perlu memisahkan diri dari para pesaingnya serta semakin me...

Background: Patient safety (PS) is a global priority for achieving quality healthcare. Although patient engagement (PE) is a crucial risk-reduction strategy, research on this subject in Indonesia is scarce. Aim: This study aims to explore healthcare recipients’ (HCRs’) perspectives and their potential role in PS. Methods: Exploratory qualitative re...

Background: Ovarian cancer management has not yet given a satisfactory result, and the recurrence rate is still high. One of the reasons for this is resistance to chemotherapy. Melatonin and cisplatin may be involved in the chemotherapy resistance of ovarian cancer. Methods : A laboratory experiment was performed using melatonin and cisplatin in th...

In Indonesia, cervical cancer is the second most common cancer in women after breast cancer. The low level of VIA examinations by women is due to several internal and external factors. This study determines the factors that influence the early detection of cervical cancer. The update in this research is with the high cost of Pap smear examination,...

All parties involved in health care, including patients and their families/caregivers play a significant role to achieve patient safety. Furthermore, patient engagement (PE) has not been adequately implemented to achieve safe healthcare in Indonesia, despite the introduction of the patient-centered care paradigm. This study aims to explore healthca...

The COVID-19 pandemic, the growth of smartphones, and the internet have driven the use of technology for monitoring TB patients. Innovation in management of TB patients is needed to improve treatment outcomes. The study was conducted to obtain a predictive model of medication safety and solution model for at-risk patients, and to improve medication...

Objective: To prove the effect of the combination of cinnamon bark extract with cisplatin in reducing efflux and increasing influx in SKOV3 ovarian cancer cell cultures by measuring the expression of p-glycoprotein, CTR1 and the annexim V. Methods: This research is an experimental study using SKOV3 ovarian cancer cells stored in the SCTE IMERI FKUI...

Background: Ovarian cancer is fifth most common female cancer and third most common cancer in Indonesia, but most are advanced stage patients that experiencing recurrence, which indicates resistance to treatment especially to cisplatin. Melatonin appears as an alternative that can support apoptotic effect of cisplatin as a chemotherapy regimen. Aim...

Background: Studies on safety culture maturity in health care is very rare, and the existing ones only focus on patients and the use of Manchester Patients Safety Framework (MaPSaF) instrument. The objective of this study is to develop a comprehensive instrument for measuring safety culture maturity in hospitals. Design and methods: This study u...

Stunting, the condition of chronic malnutrition since 1000 days of a child's life is still a health problem in Indonesia, ranked second in the world. The causes of stunting include poor parenting, lack of antenatal care, barriers to access to nutrition and clean water, and infection in child. Stunting prevention plays an important role in tackling...

Aldose Reductase (AR) is an important factor in the pathogenesis of several Diabetes Mellitus (DM) complications, including diabetic neuropathy (DN). Vitamin D has a direct effect on the pathogenesis of DN. Aldose reductase inhibition is an important element in the prevention of DM complications. The objective of this paper was to assess the effect...

Background: Advance in screening strategies and management had steadily decreased the mortality rates of breast cancer. In developing countries, conducting screening and early diagnosis of breast cancers may face several problems. This systematic review aims to determine factors affecting the delayed diagnosis of breast cancer in developing countr...

Perencanaan strategis merupakan hal yang sangat menentukan arah perkembangan Rumah Saki tuntuk mencapai visi dan misi rumah sakit. Tujuan penelitian ini adalah untuk mengetahui kondisi internal dan eksternal RSUD Sawah Besar sehingga memiliki rencana strategi pengembangan rumah sakit. Penelitian ini merupakan penelitian deskriptif dengan pendekatan...

Perencanaan strategis merupakan hal yang sangat menentukan arah perkembangan Rumah Saki tuntuk mencapai visi dan misi rumah sakit. Tujuan penelitian ini adalah untuk mengetahui kondisi internal dan eksternal RSUD Sawah Besar sehingga memiliki rencana strategi pengembangan rumah sakit. Penelitian ini merupakan penelitian deskriptif dengan pendekatan...

Shackling a person with schizophrenia violates human rights. This process is often carried out when the person has committed acts of violence and hostility. In this study, we focus on considering the shackling of a person with schizophrenia in Indonesia’s context. We used grounded theory (GT; Charmaz, 2011) with 23 participants located in the East...

BACKGROUND: Initial smoking exposure may occur during early adolescence (aged 10–12 years old), and it increases overtime. Although several factors for smoking behaviors exist among adolescents, there are few studies address determinant of smoking behavior by adding others variables in theory of plan behavior such as smoking refusal skills, self-re...

Introduction. Diabetic neuropathy (DN) is the most common form of neuropathy in developed countries. Diabetic duration and glycemic control are risk factors for DN. Evidence that vitamin D can improve glycemic control is still uncertain. In some literatures, there are conflicting reports on the effect of vitamin D on nerve conduction studies (NCSs)...

In this era of COVID-19, suspected breast cancer patients experience delay in diagnosis due to the fear of contracting the virus and reduction of non-COVID-19 health services. Furthermore, it may lead to potential increase in the incidence of advanced cancers in the future. Ultrasound-guided (US-guided) percutaneous core needle biopsy (CNB) is a gr...

Introduction: Breast cancer is the second most frequent cancer worldwide. The main therapeutic modality for breast cancer with brain metastases is radiation. Whole Brain Radiotherapy (WBRT) is a treatment that provides moderate doses of radiotherapy to all brain tissue. Capecitabine was found to be effective for the treatment of breast cancer with...

BACKGROUND Cancer is a complex disease requiring a multidisciplinary approach in establishing prompt diagnosis and treatment. Treatment in a timely manner is crucial for the outcomes. Hence, this study aimed to provide information on treatment delay including patient and provider delays and its associated factors. METHODS Cancer patients were recr...

Layanan kesehatan gigi dan mulut adalah salah satu jenis pelayanan yang disediakan oleh rumah sakit. Pemanfaatan poliklinik gigi di Rumah Sakit Satya Negara masih cukup kurang, yang terlihat pada laporan 3 tahun terakhir terjadi penurunan jumlah kunjungan pasien poliklinik gigi. Tujuan penelitian ini adalah untuk menyusun strategi pemasaran yang te...

Background: Tuberculosis (TB) is an infectious disease that is a major problem in Indonesia, placing Indonesia among the three major countries with the highest TB cases in the world. In addition, reporting of TB data from health service facilities, especially hospitals, is still weak. Since the implementation of Directly Observed Treatment Shortco...

BACKGROUND:Initial smoking exposure may occur during early adolescence (aged 10 to 12 years old), and it increases over time. Although several factors for smoking behaviors exist among adolescents, there is few studies address determinant of smoking behavior by adding others variables in theory of plan behavior such as smoking refusal skills, self-...

Background: Stigma is one of the main factors causing pasung (physical restraint or confinement in Indonesian terms) in schizophrenia patients. It is the main obstacle to reducing the number of pasung throughout the world. Thus, there is a need for appropriate interventions to reduce stigma in schizophrenia patients who go through pasung. This stud...

Objectives: We sought to assess the modulation of interleukin-8 (IL-8) production by vitamin D supplementation in Indonesian patients with diabetic polyneuropathy (DPN). Methods: We conducted a cohort prospective, randomized, placebo-controlled, double-blind trial. This study was approved by the Local Ethical Committee and conducted from July 20...

AIM: This study aimed to examine the relationship between transformational leadership, organizational commitment, work stress, and turnover intentions of Nurse at Private Hospital in Indonesia. METHODS: A quantitative cross-sectional research design was adopted, consist of 97 Nurses. This study used a Confirmatory Factor Analysis, Structural Equati...

Objective: To prove the effect of giving black cumin seed extract (Nigella sativa) to decrease levels of TNF-α, IL-2, sFlt-1, and in PE model mice. Methods: This study is an analytical study with true experimental research design in laboratory mice (Rattus norvegicus) pregnant female has given black cumin seed extract (Nigella sativa) at a dose of...

Objective: This research aimed to show effect of black cumin (nigella sativa) on blood pressure, mean arterial pressure (MAP), proteinuria in preeclamptic model rats. Methods: This is analytical research with true experimental design in laboratory pregnant female rats (Rattus norvegicus), which get black cumin seed extract (Nigella sativa) at a dos...

Objective: Breast cancer is the second most frequent cancer worldwide. The main therapeutic modality for breast cancer with brain metastasis is radiation. Whole Brain Radiotherapy (WBRT) is a regional treatment that provides moderate doses of radiotherapy to all brain tissue. Capecitabine was found to be effective for the treatment of breast cancer...

INTRODUCTION: Mothers have an important role in childhood obesity. The role of the mother is influenced by self-care, self-efficacy, child health status, and health information obtained by mothers who form health literacy in the prevention of obesity in children. AIM: The aim of this study was to determine the health behavior prediction model base...

Objective: This study is the first study to test the effect of andaliman on preeclampsia. This study aims to discover whether andaliman fruit extract (Zanthoxylum acanthopodium DC) affects the level of TNF α and IL-6 in preeclamptic LPS Induces mice Methods: This study uses analytical research with quasi-experimental research design in laboratory r...

BACKGROUND: Keloid is a benign fibroproliferative dermal disorder as a result of dysregulation wound healing process in susceptible individuals. The pathogenesis is not clearly known yet, but upregulation of transforming growth factor-β1 (TGF-β1) was found to have a significant role in inducing hyperproliferation of fibroblast cells. Roselle (Hibis...

Background: Several observational studies in Diabetes Mellitus (DM) patients show a significant relationship between vitamin D deficiency and paresthesias, numbness, but also between neurological deficits and electrophysiological. Objectives: The aim of this study was to evaluate association of vitamin D level with Baba's Diabetic Neuropathy Classi...

BACKGROUND: Type 2 Diabetes Mellitus is one of the most common metabolic diseases worldwide. The most common complication of DM is diabetic neuropathy (DN), especially diabetic polyneuropathy (DPN). Vitamin D plays an important role in the pathogenesis of DN, thus affecting its severity which can be assessed using nerve conduction study (NCS). AIM...

Background. Dengue fever is the most serious consequence of mosquito-borne infection worldwide. The pathophysiology of DHF in human is complex which involve endothelial cell activation and impaired endothelial barrier leading to plasma leakage triggering the activation of the haemostatic system. The increased vascular permeability may lead to hypov...

Background: Indonesia is the country with the second highest number of tuberculosis in the world. Patient compliance with tuberculosis treatment is still very low. Thus the success rate of treatment is also unsatisfactory. Concordance behaviour is a model of the doctor-patient relationship that combines aspects of the partnership, sharing decision...

BACKGROUND: Reducing maternal mortality is one of the targets in the Millennium Development Goals (MDGs). In a systematic review, 4.6 per cent (95% CI 2.7-8.2) of pregnancies were complicated by preeclampsia worldwide. Preeclampsia occurs in around 10% of pregnancies in the world whereas developing countries contribute more than developed countries...

AIM: To study the dimensional analysis CD44high CD24low and Ki67 in triple negative breast cancer (TNBC). METHODS: This cross-sectional study was performed on patients with breast cancer in Haji Adam Malik Hospital Medan from 2013 to 2016 to determine the frequency and pathologic features of TNBC by immunohistochemistry stained. RESULTS: By using...

Objective: To determine the risk factors of caries among adolescents in Padang City, by assessing the frequency of sugary snack consumption. Material and Methods: A cross-sectional study was conducted on 150 randomly selected junior high school students using a self-administered questionnaire along with oral examinations. The questionnaire consiste...

Study on specific genetic pathways of condylar phenotype variation related to vertical mandibular asymmetry remain rare. PITX2Study on specific genetic pathways of condylar phenotype variation related to vertical mandibular asymmetry remain rare. PITX2, a gene active in the Nodal Pathway that determines the left-right symmetry during embryogenesis,...

The proper diagnosis of the dentocraniofacial symmetry is a major step in modern orthodontics. Mandibular condyle is the most likely region of temporomandibular joint with the most advanced post-pubertal growth rate. The asymmetrical function of the mandibular that has developed differently, is a naturally occurring phenomenon. However, the dysfunc...

BACKGROUND: Asthma is a chronic airway disease that is based on an inflammatory process and a serious health problem around the world. Asthma is often associated with treatment management factor. Adherence is the patient’s compliance towards their doctor's advice, which is accompanied by their understanding and follows the doctors’ advice consisten...

Asthma problems are often linked to treatment management factors which include the non-maximal behavior of the patients and doctors. The adherence concept emphasizes a strong commitment between physicians and patients to achieve maximum behavior towards the treatment. This study aimed to construct a model of adherence to treatment of patients with...

Objective: To develop and validate a risk score model for recognizing prediabetes among Indonesian adults in primary care. Methods: This was a cross-sectional diagnostic study. After excluding subjects with diabetes from Indonesian National Basic Health Survey (INBHS) data set, 21,720 subjects who have completed fasting plasma glucose test and aged...

Objective To develop and validate a risk score model for recognizing prediabetes among Indonesian adults in primary care. Methods This was a cross-sectional diagnostic study. After excluding subjects with diabetes from Indonesian National Basic Health Survey (INBHS) data set, 21,720 subjects who have completed fasting plasma glucose test and aged...

One of the functions of hospital bylaws are a means to provide legal protection for all all parties that are related to the hospital. Legal protection is essential for prosecuted hospital staff members. One of the reasons for indictments is adverse events. The goal of this research is to discover how the hospital by-laws protects the hospital staff...

Objective: Early childhood caries (ECC) is a health challenge in Indonesia. It causes problems with mastication and digestion, and causes growth and speech disorders, as well as low self-esteem. The prevalence and severity of ECC is increasing. Thus, the study objectives were to analyze the relationship between dental caries activity in mothers and...

Background and Objective: Many instruments have been developed to measure oral health-related quality of life for dental disease, however, no measurement available on clinical consequences of untreated dental caries, specifically for children. The aim of this study was to develop an instrument in this purpose derived from child oral health-related...

In Indonesia, to determine the presence of emotional stress as a risk factor for temporomandibular disorders (TMD) is still difficult. Although the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) axis II could be used to detect any symptoms of depression butit is not suitable for Indonesian society. The aim of this study was...

This study was performed to determine the correlation between aldehyde dehydrogenase-1A1 (ALDH1A1) level and tumor shrinkage after chemoradiation in locally advanced rectal cancer. This is a retrospective study of 14 locally advanced rectal cancer patients with long course neoadjuvant chemoradiation. ALDH1A1 level was measured using ELISA from para...

This paper analyzed the Policy Implementation of Community Health Center (CHC) as Report Obligation Recipient Institution for Narcotic Addicts in Jakarta Province in 2014. The design of the study employed a mixed methods approach of Sequential Explanatory. The implementation analysis employed the model developed by Donald Van Meter and Carl Van Hor...

strong>Background and Purpose : Neoadjuvant chemoradiation (CRT) is the mainstay treatment for locally advanced rectal carcinoma. However, the response is varied due to many factors, including tissue hypoxia. Osteopontin (OPN) is an emerging endogen hypoxic marker with significant correlation towards tumor pO2, also a more accurate chronic hypoxic...

Tooth loss may be a modifiable risk factor for dementia, but the causal relationship has not been evaluatedsufficiently. The purpose of this study was to investigate the association between tooth loss and dementia on the Indonesian elder. The subjects consisted of 208 volunteers (36 males and 172 females) aged 60 years or older. The mini mental sta...

Background: Delayed union, nonunion, and mechanical failure is still problems encountered in limb salvage surgery (LSS) using extracorporeal irradiation (ECI). This study aimed to determine whether bone marrow mesenchymal stem cells (MSC) and recombinant human bone morphogenetic protein-2 (rhBMP-2) improve hostgraft union after osteotomy and also...

Background: This study was aimed to compare the effect of laser photocoagulation (LF), intravitreal bevacizumab (IVB) and combined treatments on biomarkers of oxidative stress such as aldehhyde dehidrogenase (ALDH), malondialdehyde (MDA) level, superoxide dismutase (SOD) activities, and vitreal vascular endothelial growth factor (VEGF) on prolifera...

Objective : Ultraviolet irradiation is the major external factors that cause skin photoaging. Ultraviolet B (UVB) irradiation induces the production of matrix metalloproteinase (MMP) by activating cellular signaling transduction pathways, which are responsible for the degradation of collagen. The imbalance between collagen degradation and synthesis...

Background: Scaffold (biomaterial) biocompatibility test should be performed in vitro prior to in vivo stem cell application in animal or clinical trial. These test consists of direct and indirect toxicity test (MTT assay [3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide]). Those tests were used to identify cell morphological changes,...

Indonesia is in progress to achieve her MDG goals, and some show promising, but no all. Problems are rooted to low ability of public health workers in all levels. There are more than 180 public health higher education programs, unstandardized and only 50% accredited. Based on that situation, the Indonesian Public Health Association in collaboration...

Pemberdayaan masyarakat adalah salah satu strategi dalam pembangunan kesehatan yang digunakan oleh pemerintah Indonesia. Pemberdayaan masyarakat ini menjadi salah satu fungsi puskemas yang wajib dijalankan oleh seluruh puskesmas di tanah air. Walaupun strategi pemberdayaan masyarakat sudah lama digunakan, sampai sekarang belum ada instrumen spesifi...