Adam Schuller

Adam Schuller
Boise State University | BSU · Department of Community and Environmental Health

Bachelor of Science

About

5
Publications
146
Reads
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8
Citations
Introduction
Interests: differential DNA methylation as a mechanism underlying disease progression; environmental origins of neurodegenerative disease; epigenetic techniques in forensic science.
Additional affiliations
January 2020 - present
Boise State University
Position
  • Research Assistant
Description
  • Investigate the relationship between environmental woodsmoke, epigenetic modifications, and Alzheimer's disease. Specifically interested in effects of DNA methylation on neuroinflammation and contributions to amyloid beta and tau pathologies.
November 2018 - July 2019
The University of Akron
Position
  • Research Assistant
Description
  • Involved in ongoing work regarding effects of chronic opioid use on cortical bone remodeling in a rabbit model.
January 2016 - May 2017
Northeast Ohio Medical University
Position
  • Research Assistant
Description
  • Assisted with projects characterizing cytokine profiles in AD and glaucoma mouse models. Visualized neuro-pathology using fluorescence microscopy and immunohistochemistry. Quantified protein using ProteinSimple Wes platform.
Education
August 2020 - May 2024
Boise State University
Field of study
  • Biomolecular Science
August 2015 - May 2019
University of Akron
Field of study
  • Biology

Publications

Publications (5)
Article
Full-text available
Woodsmoke poses a significant health risk as a growing component of ambient air pollution in the United States. While there is a long history of association between woodsmoke exposure and diseases of the respiratory, circulatory, and cardiovascular systems, recent evidence has linked woodsmoke exposure to cognitive dysfunction, including Alzheimer’...
Article
Full-text available
Wildfires are now a common feature of the western US, increasing in both intensity and number of acres burned over the last three decades. The effects of this changing wildfire and smoke landscape are a critical public and occupational health issue. While respiratory morbidity due to smoke exposure is a priority, evaluating the molecular underpinni...
Article
Background: Visual disturbances often precede cognitive dysfunction in patients with Alzheimer's disease (AD) and may coincide with early accumulation of amyloid-β (Aβ) protein in the retina. These findings have inspired critical research on in vivo ophthalmic Aβ imaging for disease biomarker detection but have not fully answered mechanistic quest...
Article
Full-text available
Due to the high prevalence of opioid prescription following orthopedic procedures, there is a growing need to establish an animal model system to evaluate the effects of opioids on bone remodeling. Rabbits have been employed as model organisms in orthopedic research as they exhibit well-defined cortical bone remodeling similar to humans. Existing r...
Poster
In the Htau model of Alzheimer’s disease (AD), one which expresses neurofibrillary tangle (NFT) pathology, a bone mineral density (BMD) deficit has been observed. This phenotype has been correlated with significant loss of tryptophan hydroxylase (TPH) positive cells in the dorsal raphe nucleus (DRN), a region known to play a role in bone modulation...

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Projects

Project (1)
Project
To characterize extra-pulmonary effects of wildfire smoke exposure using molecular techniques to analyze changes in epigenetic patterns, protein expression, and enzyme activity.