Abimbola Pius Okiki

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Verified

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• DVM, MSc, PhD
• Professor (Full) at Afe Babalola University

Background Prolonged exposure to LED‐light has been associated with impaired sleep quality and pathogenesis of various diseases, including Alzheimer’s Disease (AD). Red light therapy has been indicated as a non‐invasive way of reducing anxiety, mood and sleep optimization in neurodegenerative disorders but its endogenous mechanisms are insufficient...

Background Prolonged exposure to LED‐light has been associated with impaired sleep quality and pathogenesis of various diseases, including Alzheimer’s Disease (AD). Red light therapy has been indicated as a non‐invasive way of reducing anxiety, mood and sleep optimization in neurodegenerative disorders but its endogenous mechanisms are insufficient...

Schistosomiasis, or Bilharziasis, is a neglected tropical disease caused by Schistosoma parasites, which significantly impacts public health, particularly in Africa. Schistosoma haematobium, the primary species responsible for urogenital schistosomiasis (UGS), is associated with severe chronic conditions, including squamous cell carcinoma (SCC) of...

Bacteriological investigations were carried out on reported cases of low and high mortalities in commercial poultry in the year 2007-2009 in commercial flocks of breeders, layers, broilers, chicks and growers. Pure bacterial isolates obtained from dead birds, mainly Gram negative, were tested for their biochemical and antibiotic susceptibility prof...

The numerous health advantages of citrus fruits are generally well-known. Therefore, this study investigated bioactive properties of ethanol extracts and volatile oils of three citrus fruits (orange, grape and tangerine) wastes. The antioxidant activities of the extracts and volatile oils were assessed using the 2, 2-diphenylpicrylhydrazyl (DPPH) r...

Hepatitis is an inflammatory disease of the liver which can be acute or chronic. It can be caused by viruses (viral hepatitis), certain chemicals, drugs, prolonged or excessive consumption of alcohol (alcoholic hepatitis), some genetic abnormalities or a dysfunctional immune system (autoimmune hepatitis). And of the five types of viral hepatitis, H...

Blood is a life-saving resource. Despite the significance of blood transfusion in saving a millions life in emergencies and medical treatment, the safety of blood transfusion faced challenges of transmitting life threatening transfusion transmissible infectious agents such as hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficie...

Xanthomonas is a genus of proteobacteria that causes plant diseases and affects many crops around the world, including tree crops, leaf and fruit vegetables, cereals, tubers, and other crops. The goal of this study was to conduct comparative analyses of morphological, genetic, and virulence factors, as well as to determine the genotype distribution...

Background Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is one of the top infectious killer diseases in the world. The emergence of drug-resistant MTB strains has thrown challenges in controlling TB worldwide. This study investigated the prevalence of drug-resistant tuberculosis in the states of Nigeria and the risk factors that c...

Microorganisms colonizing the oral cavity have a significant probability of spreading on epithelial surfaces to neighboring sites. Many reports have associated oral bacteria to oral infectious diseases as well as systemic diseases such as cardiovascular disease and diabetes. Oral care is usually neglected in the control of health problems linked wi...

The experiment investigated the effects of various soya bean groups (boiled, fermented, and roasted) on Japanese quail at 3 weeks old. 160 Japanese quail were randomly assigned to four treatments (control, boiling soya beans, fermented soya beans, roasted soya beans) with four duplicates each. The 12-week trial lasted. Data on weekly body weights a...

The study was aimed at assessing the nutritional and medicinal properties of nutmeg, a seed of Myristica fragrans Houtt. Locally sourced nutmeg in Ado-Ekiti, Nigeria, were analysed for their proximate, minerals, vitamins, phytochemicals and bioactive molecules contents. GC-MS analysis of the essential oil was carried out and drug properties of the...

Malaria is a life-threatening disease caused by protozoan Plasmodium species. Plasmodium falciparum is the deadliest species. Reducing and eliminating malaria burden are linked to most of the Sustainable Development Goals (SDG), central to SDG3 targeting the end of malaria by 2030. This study was aimed at assessing the Management of malaria and pre...

Schistosomiasis, also known as bilharzia, is a disease caused by blood flukes of the genus Schistosoma. The most impacted countries are those in Sub-Saharan Africa, which accounts for nearly 90% of the world’s estimated 236.6 million cases. The study was aimed at investigating the occurrence of significant bacteriuria among schistosomiasis positive...

The World Health Organization reported 241 million cases and 627,000 death from malaria in 2020 and Nigeria accounted for 27% of malaria death worldwide. Effective tools are continually developed through global efforts to have a malaria-free world. The study was aimed at assessing the prevalence and management of falciparum malaria among febrile pa...

This study was conducted to determine the prevalence of Hepatitis B and D antibodies among pregnant women attending antenatal clinic at Ekiti State University Teaching Hospital (EKSUTH), Ado-Ekiti. Structured questionnaires were administered to obtain their socio- demographic data. The study made use of consecutive sampling design. A total of 350 p...

Bacterial vaginosis (BV) is a common vaginal disorder in women of the reproductive age group that causes offensive vaginal discharge. BV occurs when Lactobacillus spp., the predominant species in healthy vaginal flora, are replaced by anaerobic bacteria, such as Gardnerella vaginalis. The prevalence is about 15-30% of women of reproductive age grou...

Garcinia kola otherwise known as bitter kola has been used in traditional African medicine for centuries, and is considered to have many beneficial properties. The study was aimed at assessing the nutritional and bioactive components of bitter kola chips. Freshly harvested seeds of Garcinia kola were purchased from local markets in Ado Ekiti, Niger...

The development of resistance among pathogenic microorganisms against conventional or standard antimicrobial drugs has given rise to the need for alternative approaches to therapeutic measures. The methanol, ethanol, acetone, and aqueous extracts of leaves and seeds of Phyllanthus amarus were screened for phytochemical constituents and antimicrobia...

The knowledge of the pharmacokinetic properties of Garcinia kola seeds has led to its increased consumption in places where it is indigenous thereby making its safety assessment at high doses a necessity. The study was carried out using twenty five male adult wistar which were assigned into five groups (n=5). Negative control group (I) received 25...

Traditional medicine also known as indigenous or folk medicine comprises of knowledge systems that developed over generations within various societies before the era of modern medicine. Plants are generally used for treatment of bacterial infections though they are not clinically regulated due to lack of awareness and enough data to support the rep...

The field of biotechnology has witnessed a significant achievement over the past decades. Although biotechnology always sparked a great deal of ethical criticism, the advancement has continued to offer an opportunity to address several social and economic challenges. The potentials of biotechnology remain underexploited in several fields in Nigeria...

RNAi technology is currently employed as an alternate control measure for agricultural pests. However, the variability of RNAi efficiency in insect pests limits the extensive usage of this technology and demands identifying the best target gene for effective RNAi. Four different bacterially-expressed dsRNA and purified dsRNAs coated on artificial d...

Tuberculosis is an age-long disease that has proved challenging to eradicate. In 2019 about 10 million people fell ill of TB and it has caused 1.2 million deaths among HIV negative people and 208,000 deaths among HIV positive individuals [1]. The reduction in incidence rate between 2015 and 2019 was 9% and global target for 2030 is 80% [1]. For the...

Abstract Introduction: the recent zoonotic coronavirus virus outbreak of a novel type (COVID-19) has necessitated the adequate understanding of the evolutionary pathway of zoonotic viruses which adversely affects human populations for therapeutic constructs to combat the pandemic now and in the future. Methods: we analyzed conserved domains of the...

Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly prevalent pathogen. We studied the prevalence of MRSA and its association with vaginitis during pregnancy. Bacteriological investigations of high vaginal swabs of 350 healthy pregnant women attending antenatal clinics were carried out. Staphylococci were isolated from high vagina...

The recent zoonotic coronavirus virus outbreak of a novel type [COVID 19] has necessitated the adequate understanding of the evolutionary pathway of zoonotic viruses which adversely affects human populations for therapeutic constructs to combat the pandemic now and in the future. We analyzed conserved domains of the severe acute respiratory coronav...

The recent zoonotic coronavirus virus outbreak of a novel type [COVID 19] has necessitated the adequate understanding of the evolutionary pathway of zoonotic viruses which adversely affects human populations for therapeutic constructs to combat the pandemic now and in the future. We analyzed conserved domains of the severe acute respiratory coronav...

Enterococcus faecalis is a major cause of nosocomial infection in human and severe extra-intestinal infections in animals. Enterococcus spp possesses the ability to acquire and spread genes linked with antimicrobial resistance which makes them an important nosocomial pathogen. This study aims to determine the distribution of antibiotic resistance a...

Introduction: Tuberculosis is a major cause of disability and death worldwide. One of the targets of Sustainable Goal Development for 2030 is to put an end to tuberculosis epidemics. This study accessed the occurrence of tuberculosis, its co-infection with HIV and rifampicin resistance in the study area, as well as the reliability of acid fast baci...

With Enterococcus species in the leading cause of nosocomial infections and resistance to an array of antibiotics, this study focused to determine the frequency and distribution of vancomycin-resistant Enterococci, the presence of virulence genes and to determine the relative nucleotide sequence relatedness among isolates using 16S rRNA sequence. A...

Abstract Objective: This study investigated possible hematological and biochemical effects of eigth-week exposure to an indoor Wi-Fi on male rats. Methods: Experimental animals were divided into four groups; group 1 (control: without exposure), groups 2 to 4 were exposed to a 2.5 GHz EMF emission from an installed indoor Wi-Fi device for 4, 6 and...

Aims: Rhizome of turmeric is known to possess therapeutic activities and has been used in medical practice as an anti-diabetic, hypolipidemic, hepatoprotective, anti-diarrheal, and anti-asthma agent. This study was designed to investigate the anti-inflammatory and antimicrobial activities of Curcuma longa. Methodology and results: Rhizomes of Curcu...

Nono is a spontaneously fermented yoghurt-like milk product consumed is a staple food commodity in parts of the Sub- Saharan West Africa. Nono is usually consumed along with 'Fura' as 'Fura da Nono' in Nigeria. Studies on physicochemical and bacteriological qualities were carried out on samples of Nono obtained from 5 different sources in Ado-Ekiti...

Rhizomes of Curcuma longa (Turmeric) purchased from local farmers in Ado Ekiti, Nigeria, were analysed for their nutritional, phytochemical and antimicrobial properties as well as the bioactive constituents of its essential oil. The dried rhizomes were found to be rich in energy, protein, carbohydrate and fat, with high concentrations of Ca2+, Fe2+...

The study was aimed at assessing the physicochemical properties and antimicrobial qualities of ‘ABUAD moringa soap’, a herbal soap produced with Moringa oleifera leaf by ‘ABUAD Farm’, Afe Babalola University, Ado Ekiti, Nigeria. The physicochemical properties and antimicrobial qualities of ABUAD moringa soap on some selected bacteria and fungi were...

The study reports bacteriological investigations carried out on a case of high mortality (10%) reported over a period of one week in a flock of turkey, 450 in number, aged 16 weeks old, in a poultry farm in Ado-Ekiti, Nigeria. Clinical signs were those of weakness, recumbence, diarrhoea (yellowish to greenish in colour) and weight loss. Post morter...

The occurrence of fascioliasis among cattle slaughtered for consumption at the Ekiti central abattoir was investigated using the faecal sedimentation concentration technique, as well as gross and histological investigations of liver tissues. Three hundred and fifty cattle slaughtered for consumption at Ado Ekiti Central Abattoir in Ekiti State, Nig...

The poultry industry in Nigeria keeps expanding on a daily basis and it is faced with the problem of egg glut almost yearly. Most of the poultry are raised in rural environments where there is no available and avoidable power supply for egg preservation. The study was aimed at using locally available and cheap materials for preservation of eggs qua...

The poultry industry in Nigeria keeps expanding on a daily basis and it is faced with the problem of egg glut almost yearly. Most of the poultry are raised in rural environments where there is no available and avoidable power supply for egg preservation. The study was aimed at using locally available and cheap materials for preservation of eggs qua...

Leaves of Euphorbia heterophylla (Milk weed) is frequently used in herbal medicine for curing of several conditions in many parts of Nigeria. The study was aimed at elucidating the leaves' anti-inflammatory potentials and mechanisms of action. The leaves were assessed for their phytochemical contents. The in vitro anti-inflammatory activities of me...

The study was aimed at using waste-soil fungi for production of cellulase enzyme. Fungi were isolated from soil samples obtained from Odo-Aremu dumping sites in Ado-Ekiti, Nigeria. Three fungal species namely Aspergillus niger, Aspergillus flavusand Trichoderma spp. were isolated. The fungal isolates were assayed for their ability to produce cellul...

Mycological investigation was carried out on soil samples from different parts of Ado Ekiti, including lands with heavy spillage of used engine oil. The isolated fungi from soil samples were tested for lead tolerance and biosorption. Fungal lead tolerance was determined at 500 – 2000ppm, while lead biosorption was determined at a concentration of 1...

The study assessed the prevalence of symptoms of asthma among Nigerian poultry workers and the possible pathological changes in lung associated with dust exposure through an indirect experimental exposure of poultry dust to albino rats. Questionnaire was developed to elicit data on symptoms of asthma, and administered to 250 poultry workers as well...

This study was designed to investigate the prevalence of pathogenic microorganisms associated with vaginitis among women of reproductive age in Owo, Nigeria and its environment. Sixty five women visiting the gynaecology unit of the Federal Medical Centre Owo were recruited for this study between December 2010 and May 2011. High vaginal swabs were o...

Bacteriological investigations were carried out on faecal samples of 76 patients, less than one year of age, attending paediatric clinic of Ekiti State University Teaching Hospital Ado Ekiti and two Primary Health Centres in Ado Ekiti, on diarrhoea related illnesses; in the year 2013. The bacteria isolated were Proteus vulgaris, Pseudomonas aerugin...

This study was designed to investigate the bacteria found in association with respiratory tract infections (RTI) and the susceptibility of such bacteria to aqueous and methanolic extracts of Zingiber officinale (ginger). Bacteriological studies were carried out on sputum from 110 patients, made up of 57 males and 53 females, aged 24-80 years, atten...

The study was carried out to determine the effects of methanolic extract of Moringa oleifera on bacterial isolates from urine of patients with urinary tract infection (UTI). One hundred and fifty urine samples were collected for this study at Ekiti State Teaching Hospital, Ado Ekiti, Nigeria, between March 2015 and June 2015. Ethical clearance was...

Phyllanthus amarus is valued in many countries its broad spectrum of pharmacological activities for a variety of ailments. The study evaluated and compared the nutritional and phytochemical components of the dried leaf and seed of the plant. Proximate analysis revealed that both leaf and seed are rich in carbohydrate and energy, low in fat, ash, cr...

Moringa oleifera is a plant that is in high demand for its nutritional and medicinal values. This study was aimed at assessing the nutritional and phytochemical constituents of the leaf of Moringa oleifera cultivated in Ado Ekiti, Nigeria. Samples of leaf of M. oleifera were obtained from six different moringa cultivating locations in Ado Ekiti. Th...

Background: The assessment of maternal immunity of poultry birds transferred to young chicks was carried out using both local breed and broiler chickens, with an objective to determine the antibody level pattern and hematological parameters of chickens in the first thirty one (31) days of life. Method: One hundred and twenty birds were used for t...

The study was designed to detect fungi and quantify aflatoxins B1 and B2 microbial load levels and toxin binding efficacy of hydrated sodium calcium aluminosilicate (HSCAS) on growth and nutrient utilization of Clarias gariepinus African catfish fingerlings diet formulated with mouldy groundnut cake (MGNC). MGC containing 185.00 ± 7.07 μg/kg and 13...

Bacteriological investigation was carried out on the meat processing equipments and environment where animals were slaughtered at the central abattoir in Ado Ekiti in this study. Samples were collected from equipments such as knives, buckets, tables etc used in meat processing from the central abattoir in Ado Ekiti and also from the environment of...

The study was aimed at assessing the prevalence of mites in poultry dust and its possible contribution to respiratory diseases among the Nigerian poultry workers. Settled dusts from 20 poultry confinements were analysed for the presence of mites. Questionnaire was administered to assess the symptoms of respiratory ill-health and socio-demographic p...

This study was conducted to assess the health implications of feeding broiler chicken with diet naturally contaminated with mycotoxins, because of frequent compromise with quality of poultry feed in countries with developing economy. Eighty day old Anak Titan broiler chickens were randomly divided into two groups of forty chickens with each group r...

The assessment of maternal immunity of poultry birds transferred to young chicks was carried out using both local breed and broiler chickens, with an objective to determine the antibody level pattern and hematological parameters of chickens in the first thirty one (31) days of life. One hundred and twenty birds were used for the study. Ninety (90)...

Bacteriological investigations were carried out on reported cases of low and high mortalities in commercial poultry in the year 2007-2009 in commercial flocks of breeders, layers, broilers, chicks and growers. Pure bacterial isolates obtained from dead birds, mainly Gram negative, were tested for their biochemical and antibiotic susceptibility prof...

Industrialized agriculture has resulted in a public health crisis for farmers, farm workers and their families. This study, which involved measurement of the concentrations of air-borne dust and ammonia in poultry buildings using active samplers and assessing the physical and psychological health status of poultry workers via questionnaire, was con...

An attempt was made to enumerate the micro-flora in trachea of broiler chickens challenged with Newcastle disease virus (NDV) following supplementation with different extracts of local sources. After 30 days of treatment with extracts of Aloe vera (AV), Lumbricus rubellus (LR), Archachatina marginata (AM) and G. lucidium (GL) ad libitum as suppleme...

Bacteriological investigations were carried out in both air-borne and settled dust in poultry confinements. Poultry dusts were also analysed for heavy metals and toxic chemicals. Bacterial load in settled dust and air in poultry confinements were found to be7-26 x 107cfu/g and 2-20 x 107cfu/m3 respectively. Isolated bacteria in poultry confinements...

Bacteriological investigations were carried out in both air-borne and settled dust in poultry confinements. Poultry dusts were also analysed for heavy metals and toxic chemicals. Bacterial load in settled dust and air in poultry confinements were found to be7-26 x 107cfu/g and 2-20 x 107cfu/m3 respectively. Isolated bacteria in poultry confinements...

Licenciado sob uma Licença Creative Commons [I] Micro-fungi and mycotoxins in poultry dust [I] Microfungos e micotoxinas em poeira de confinamento [A] Abstract Dust in poultry confinement facilities were investigated for their fungi and mycotoxins contents. Concentrations of mi-crofungi in the air of poultry confinement facilities were determined u...

Low production performances in Nigerian poultry industry is of a serious concern. This study, an experimental exposure of broiler chicken to feed naturally contaminated with mycotoxins, is part of the efforts to unravel this problem of low productivity. Broiler chickens aged 1 day to 8 weeks were fed with diet compounded with naturally contaminated...

Vegetable workers were assessed for the prevalence of physical and psychological ill-health, symptoms associated with avian influenza (AI), as well as, their awareness of AI pandemic threat, using structured questionnaire. Vegetable workers reported significantly higher symptoms of physical ill health than control (P = 0.002). Symptoms associated w...

Avian influenza (AI) H5NI arrived Nigeria in the year 2006 with apathy towards poultry and poultry products. Our study was conducted among residents living near poultry farms (RLNPF), who were daily exposed to emissions from poultry farms, during the AI H5NI outbreak in the year 2006 and a year later. The physical and mental health statuses were as...

Low Egg Production Performances Associated with Multi-drug Resistant Bacteria among Nigerian Commercial Layer Flocks. Nigerian Journal of Animal Production 37(1): 101-108 (Nigeria) Abstract: Bacteriological investigations were carried out on commercial layer flocks of 10 poultry farms in parts of Lagos and Ogun States of Nigeria, in the years 2005...

A stronger association has earlier been reported between drug resistant human isolates of Escherichia coli and poultry isolates of E. coli than between drug-resistant and drug-susceptible human isolates of E. coli, in their phylogenic distribution, virulence and genotypes. It has been suggested that many of the drug-resistant human isolates were mo...

Poultry workers commonly report respiratory diseases as well as symptoms of general ill health. Albino rats, used as animal model, were exposed to sieved poultry dust inhalation in an exposure chamber. Blood samples were collected from the exposed rats and analysed for their haematological and biochemical qualities. Bronchoalveolar lavage (BAL) flu...

Infectious bursal disease (IBD) outbreak was reported in a flock of 11-week-old hyaline pullets on a commercial poultry farm located in Agbado town of Ogun State, Nigeria. The diagnosis of the disease was based on clinical signs and pathological lesions followed by assessment of IBD antibody seroprofile status by the Idexx ELISA technique. Mortalit...

Infectious bursal disease (IBD) outbreaks in 3 commercial poultry farms were reported. The diagnosis of the disease was based on clinical signs and pathological lesions, followed by the Ouchterlony agar precipitation test. All the affected chickens were from vaccinated flocks. Very mortality and morbidity were recorded; 66% mortality from flocks wh...

Four hundred freshly laid table eggs, average weight 56.83 ± 3.21g, were collected from 5 different poultry farms in Lagos suburbs. Three hundred of the eggs were stored in the laboratory under ambient temperature. The remaining 100 eggs were stored in the refrigerator. The physical, nutritional and bacteriological qualities of the eggs were assess...

Investigation was carried out on the prevalence of Salmonella typhi in stools of hospitalized typhoid fever patients in Lagos metropolis. Studies were carried out between January and December 2003. Four hundred and thirty four patients were hospitalized and treated for typhoid fever in the ten hospitals monitored during the period of this study. Th...

Assessment of physical health status of wood workers in 7 saw-mills was conducted via questionnaire. Microbiological analysis of air-borne dust and settled sawdust in the sawmill environments were investigated as possible predisposing factor to ill health. A total of 258 saw mill workers and 63 controls with mean age 32.26"8.73 years (mean±S.D) and...

Bacteriological investigation of vegetables cultivated using poultry manure in Ojo town of Lagos State, Nigeria, was carried out and its attendant health risks assessed. Five vegetables commonly consumed raw were harvested, the bacterial load assessed, followed by washing separately with vinegar (4% acetic acid), normal saline and sterile distilled...

Sera obtained from 86 Yankasa breed of sheep, made up of 60 males and 26 females, were tested for prevalence of sperm antibodies by gelatine agglutination assay (Kibrick test). Seroprevalence of sperm antibodies were demonstrated in 20.93% of the sampled sheep; 23.33% of the female and 15.38 of the males tested positive. The prevalence of circulati...