Abdullah Al Noman

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Verified

Abdullah Al verified their affiliation via an institutional email.

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• Bachelor of Pharmacy
• Student at BRAC University

Cannabidiol (CBD), derived from Cannabis sativa, has gained remarkable attention for its potential therapeutic applications. This thorough analysis explores the increasing significance of CBD in treating neurological conditions including epilepsy, multiple sclerosis, Parkinson's disease, and Alzheimer's disease, which present major healthcare conce...

Aims: The aim of this study is to develop mefenamic acid-loaded microspheres using a hydrophilic polymer and a solvent evaporation method for sustained drug release, aiming to reduce the frequency of dosing. Background: Mefenamic acid is an anti-inflammatory drug commonly used to manage pain, especially menstrual cramps. Microspheres, which are sph...

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms such as tremors, stiffness, and bradykinesia, as well as non-motor symptoms like cognitive impairment and mood swings. PD is a multifactorial disease comprised of environmental and genetic etiologies. In addition to family history, Variants in the LRRK2 gene ar...

Background: Oropouche virus (OROV), part of the Peribunyaviridae family, is an emerging pathogen causing Oropouche fever, a febrile illness endemic in South and Central America. Transmitted primarily through midge bites (Culicoides paraensis), OROV has no specific antiviral treatment or vaccine. This study aims to identify host-targeted therapeutic...

Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily marked by amyloid-beta (Aβ) plaque accumulation and neurofibrillary tangles, which lead to cognitive decline. Oxidative stress and neuroinflammation are key contributors to the disease's progression, with elevated production of Reactive Oxygen Species (ROS) exacerbating...

This study aims to provide clinical and scientific information about the effects of various anti-inflammatory medicines on patients with cardiovascular disease (CVD). We also discussed the anti-inflammatory strategies and molecular mechanisms being investigated in pre-clinical or clinical CVD research. Numerous studies on anti-inflammatory medicine...

The decline of one’s cognitive skills owing to ageing along with conditions like Parkinson’s and Alzheimer’s disease is partly caused by changes in the expression of relevant genes, which do not require the sequence of DNA to be altered. This study looks at the processes of DNA methylation, histone alterations, and non-coding RNAs in cognitive decl...

Non-coding RNA (ncRNA) has been recognized to be an essential regulator of cellular processes and gene expression in cancer. The present study covers the various roles of ncRNAs, including circular RNAs (circRNAs), long non-coding RNAs (lncRNAs), and microRNAs (miR-NAs), that affect cancer properties. Oncogenesis, metastasis, and treatment resistan...

A complicated neural developmental condition, autism spectrum disorder (ASD) is marked by difficulties with social interaction, communication, and repetitive behaviours. There is increasing interest in complementary and alternative medicines, including medicinal plants, to treat the symptoms of ASD as incidence rates rise globally. This thorough an...

Pregnancy-related smoking and nicotine exposure by the mother can impact the developing brain of the baby and increase the likelihood that the kid will have autism or other neurodevelopmental disorders. However, conflicting epidemiological evidence links prenatal nicotine exposure to ASD, and the molecular processes involved remain unknown. The dat...

Cardiovascular diseases remain a significant reason for illness and death globally. Although certain interleukins have been extensively researched about cardiovascular disease (CVD), new findings have identified unique members of the interleukin family that could potentially play a role in cardiovascular well-being and ailments. This review discuss...

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline, synaptic dys-function, and neuroinflammation, with oxidative stress playing a crucial role. Coenzyme Q10 (CoQ10), known for its antioxidant properties, has been proposed as a potential therapeutic agent due to its ability to mitigate oxidative damage and ma...

Background: The interplay between breast cancer treatment and osteoporosis has important consequences for anticancer therapy and patient bone health. Many breast cancer therapies involve hormonal treatments that lower estrogen levels, which can lead to an increased risk of osteoporosis due to reduced bone mineral density. Aromatase inhibitors, chem...

This study explores the complex link between vitamin D and neurological illnesses, focusing on how vitamin D affects possible risk factors, therapeutic applications, and the trajectory of the disease. An epidemiological study has linked vitamin D insufficiency to several neurological conditions, including Parkinson's disease, Alzheimer's disease, a...

ChatGPT is one of the promising AI-based language models which has the potential to contribute to pharmacy settings in many aspects. This paper focuses on the possible aspects of pharmacy management where ChatGPT can contribute, the prevalence of its use in Saudi Arabia as a practical insight, case studies showing the potential of ChatGPT in answer...

The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spread quickly. The continuous transmission of a novel coronavirus and its capacity to spread between individuals motivated scientists to develop novel treatment strategies for future COVID-19-like pandemics. RNA-dependent RNA...

Artificial intelligence (AI) has immense potential to revolutionize pharmacy operations by simplifying procedures, improving efficiency, and expediting pharmaceutical research. Nevertheless, obstacles such as steep expenses, absence of faith in AI, worries about unemployment, threats to privacy, and the incapacity to substitute human decision-makin...

The level of evidence is a fundamental structure for assessing the excellence of evidence while making healthcare choices. It assesses medical research according to its structure, credibility, and relevance. The different degrees of proof are frequently represented as a triangle shape, with the most powerful proof on the highest point. The pyramid...

Autism spectrum disorder is a neuronal developmental disorder which is commonly established in the early age of life and persist throughout the lifespan. Currently, there are very little option of pharmacological therapies approved for use in ASD. Mainly the treatment approach is different type of therapies are used like behavioral therapy, occupat...

This paper gives an overview of therapeutic drug monitoring. The primary objectives of TDM are to prevent therapeutic failures carried on by poor compliance or prescribing a drug at a dose that is too low, as well as negative or toxic effects brought on by an excessive dose. Moreover, it gives information about when and what type of drug needs ther...

Mucormycosis is a fungal infection which is caused by a growing number of mucorales in the body. It infects people through air, soil, food or open wound. Generally, infecting immunosuppressed persons and people with Diabetes Mellitus, Diabetic ketoacidosis, organ transplant patients, autoimmune disorders, burns, and trauma. It has high mortality ra...