Abdulfatai Olakunle Ojewale

• PhD
• Lagos State University

Abstract: Introduction: The present study was designed to evaluate the nephroprotective activities of ethanolic roots extract of Pseudocedrela kotschyi against oxidative stress and nephrotoxicity in alloxan induced diabetic albino rats. Methodology: Diabetes was induced in Albino rats by administration of alloxan monohydrate (150 mg/kg, i.p). The e...

This presentation gives an exclusive pictorial and theoretical explanation of the following: -Fascia and compartments of the shoulder, proximal and distal arm, middle forearm, cubital fossa. -Anterior and Posterior axioappendicular muscles of the shoulder. - Flexor and Extensor compartment of the Forearm. - Flexor and Extensor Tendons at the wrist...

Background The Sciatic nerve (SN) depicts sex and side-associated dimorphic features that are of clinical relevancy. The study investigated the sex and side-related morphologic and morphometric variations of the nerve using cadavers. Methods A cross-sectional cadaveric study on 62 Ugandan cadavers were used. Continuous variables were reported usin...

Background: Sodium fluoride (NaF) causes testicular toxicity via an oxidative stress mechanism. Solanum aethiopicum (SAE) contains abundant antioxidant and androgenic properties. This study investigated the ameliorating potential of SAE extract against NaF-induced testicular damage in rats. Methods: Forty-eight (48) adult male Sprague Dawley rats (...

Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine and metabolic disorder, causes irregular menstrual cycles, dyslipidemia, excessive body weight, oxidative stress, hyperandrogenism, and infertility. This study focused on the impact of Cyperus esculentus (CES) on letrozole-induced PCOS in female Sprague-Dawley rats. Twenty (20) normal ra...

Gross anatomy case report

Objective: Amaranthus hybridus (AH) is a food plant commonly eaten in our country known as a good source of vitamins, minerals, and antioxidants. The present study was designed to investigate the ameliorative potentials of aqueous extract of A. hybridus on Monosodium Glutamate (MSG) -induced testicular toxicity in adult Wistar rats. Methods: Thi...

Glucocorticoid therapy has been linked with several of adverse effects which ultimately lead to diabetics, hyperlipidemia and osteoporosis. The aim of this study is to investigate the effect of N-acetylcysteine (NAC) against dexamethasone-induced renal dysfunction alteration of hematological and bone minerals indices in rats. The animals were divid...

Transfluthrin is a fast-acting insecticide used in household and hygiene products, mainly against flying insects, such as mosquito and flies, and in agriculture material pests. Its uses in these areas have not been without health risk to humans and the ecosystem. Therefore, the current study was designed to investigate the effect of smoke emanating...

Objective: To evaluate the effects of aqueous leaf extract of Adansonia (A.) digitata L on dexamethasone-induced testicular damage in male Wistar rats. Methods: Twenty adult male Wistar rats weighing 170-190 g were divided into four groups. Group栺received 0.5 mL of phosphate buffer orally for 28 days and served as the normal control group; gro...

Objectives: Lead primarily affects male reproductive functions via hormonal imbalance and morphological damage to the testicular tissue with significant alteration in sperm profile and oxidative markers. Though, different studies have reported that Cocos nucifera L. oil has a wide range of biological effects, this study aimed at investigating the...

Proton pumps are membrane-bound enzymes important in generating gradients that help in maintaining cellular ion homeostasis, cell membrane potential, water, and solute transport across the cell surface. This study investigated the modulatory role of vitamin E on proton pump activity and reproductive parameters in cadmium-induced testicular damage....

Tetrapleura tetraptera (TT) has been used as a spice, dietary supplement and medicine for various ailments. This study evaluate influence of Tetrapleura tetraptera extract on testis and copulatory behavior in sexually mature male rats. Thirty-two male and sixty-four virgin female rats weighing 150-200g were used for this study. Male rats randomly d...

Background Polycystic Ovarian Syndrome (PCOS) is a multifactorial endocrine-metabolic disorder that highly contributes to the prevalence of infertility globally. The increased consumption of refined carbohydrate, particularly fructose has been associated with pandemic metabolic disorders, including in women of reproductive age. However, the effects...

Diabetes mellitus has developed into one of the debilitating diseases disturbing the health of many people living with cardiovascular diseases in modern times. The root of Ageratum conyzoides was investigated for its effects on alloxan-induced diabetic Wistar rats’ cardiac tissues. Thirty-two (32) Wistar rats weighing between 180 and 190 g were ran...

Background: Thyroidal ultrasound has been used to detect neck lesions and nodules for decades. However, cystic thyroid disease is rare with few reported series. Different consensus exists concerning availability of medical treatment and the limited role of surgical management. Case presentation: We present a 31-year-old female with obvious neck swe...

Ethanol consumption has been linked with social and medical problems, coupled with damage of multiple organs including the cerebellum. The present study is aimed at investigating the histological and biochemical changes in the cerebellum of Wistar rats associated with ethanol exposure. The experimental animals were grouped into five groups designat...

Introduction The aim of the present study was to evaluate the hepatoprotective activities of the ethanolic roots extract of Ageratum conyzoides (AC) in alloxan-induced hepatic damage in diabetic rats. Materials and Methods Diabetes was induced in Wistar rats by the administration of alloxan (150 mg/kg, intraperitoneal). The ethanolic roots extract...

This study investigated the hepatoprotective role of ethanolic extract of Moringa oliefera (M.O) on liver function (Biomarkers) in cadmium chloride (CdCl2)-induced hepatotoxicity on the liver of albino Wistar rats. Sixty-six adult male albino wistar rats weighing between 130g – 180g were used. LD50 was determined for both CdCl2and MO using twenty-s...

This study investigated the hepatoprotective role of ethanolic extract of Moringa oliefera (M.O) on liver function (Biomarkers) in cadmium chloride (CdCl 2)-induced hepatotoxicity on the liver of albino Wistar rats. Sixty-six adult male albino wistar rats weighing between 130g-180g were used. LD 50 was determined for both CdCl 2 and MO using twenty...

Aims: The study was designed to investigate the testiculo protective effects of ethanolic roots extract of Pseudocedrela kotschyi on alloxan-induced testicular damage in diabetic rats. Study Design: Experimental diabetes using animal models. Place and Duration of Study: Department of Anatomy, College of Medicine, Lagos State University, Ikeja, Lago...

Objective: The study investigated the activities of antihypoglycemic and antihypolipidemic of ethanolic roots extract of Crossopteryx febrifuga (CF) in alloxan-induced diabetic rats. Methods: Twenty male albino rats were randomly distributed to four groups; I, II, III and IV with each consisting of five animals received extracts as follows: Group I...

This study investigated the effect of ethanolic roots extract of Pseudocecrela kotschyi on some hematological and biochemical parameters in alloxan-induced diabetic rats. Twenty-Five (25) wistar rats were randomly divided into five (5) experimental groups: control, diabetic, standard drug (glibenclamide) and Pseudocedrela kotschyi treated diabetic...