Abdul Samad

Abdul Samad
Veterinary Research Institute, Pakistan · Directorate of Archaeology and Museums

About

88
Publications
47,890
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1,173
Citations
Citations since 2017
27 Research Items
867 Citations
2017201820192020202120222023050100150
2017201820192020202120222023050100150
2017201820192020202120222023050100150
2017201820192020202120222023050100150

Publications

Publications (88)
Article
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Molecular anthropology is a new feature of archeology that can provide additional useful information to illustrate our past. Ancient DNA basically had small pieces of DNA that has been around for a long time. This DNA can be used as a sample to study different parts of a population that lived a long time ago. In order to study the continuity in mat...
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Vindoline is an important alkaloid produced in Catharanthus roseus leaves. It is the more important monomer of the scarce and costly anticancer bisindole alkaloids, vincristine, and vinblastine, as unlike catharanthine (the other monomer), its biosynthesis is restricted to the leaves. Here, biotic (bacterial endophyte, phytoplasma, virus) and abiot...
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Recent archaeological excavations at Bhamāla have brought to light many important discoveries in the history of Buddhist art and architecture. One of these is the parinirvāna statue of Buddha measuring 14 meters in length. Radiocarbon dates of the charcoal/charred wood recovered from inside the terracotta sculptures discovered inside the parinirvān...
Article
The secondary metabolites produced by the microorganisms have great importance in developing different medications, pesticides, and plant growth regulators. Curvularia lunata (Wakker) Boedijn, a plant pathogenic fungus, causes the leaf blight disease in Sweet basil (Ocimum basilicum L.). In the present study we have isolated and identified the fung...
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Catharanthus roseus produces many terpenoid indole alkaloids (TIAs) but is famous for its scarce and costly anticancer bisindole alkaloids, vinblastine and vincristine that are formed by coupling of monomeric TIAs, catharanthine and vindoline. Biosynthetic potential of the plant for bisindoles is very low due to their high cytotoxicity. The best op...
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Menthol mint (Mentha arvensis L.) is cultivated commercially for extraction of essential oil from upper ground herbage (leaves + stem). The essential oil of menthol mint is mainly used for production of menthol and the by-product dementholised oil (DMO) that find extensive applications in pharmaceutical and cosmetic industry. A new genotype of ment...
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rd to 5 th century CE) provide evidence for the early use of painted and gilt terracotta sculptures in three-quarter life size narrative panels in early Buddhist monastic institutions. A detailed scientific analysis of the terracotta sculptures discovered from the P terracotta sculptures. In the past, many of the terracotta sculptures from sites in...
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Tourism being one of the greatest and fastest growing industries of the world is contributing significantly to the development of countries and the host communities. But this industry is facing many problems in most of the developing countries including Pakistan. Most of the issues are raised due to lack of planning which not only dissatisfies the...
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Cannabis sativa L. (Cannabaceae) is one of the earliest cultivated plant, containing many of the valuable natural components useful for health as well as livelihood. Cultivation of Cannabis is done by sowing its seeds in the field provided with favourable physical and chemical parameters for germination. In this study, optimum temperature and time...
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Tourism being one of the fastest growing industries in the world is also facing many problems especially in the developing countries like Pakistan. Many of these problems really create hurdles to get the desired results that may be taken otherwise. If these problems associated with this industry are overcome, it will not only facilitate and satisfy...
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Plant pathogens damage agriculture sector to a large extent, resulted in poor crop yield and quality. A well followed practice to curb plant diseases are mostly involved with application of conventional fungicides (synthetic chemical). However, their continuous and uncontrolled use has emerged as big challenge for humans due to the hazardous effect...
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The World Heritage site of Bhamala is located on the right bank of the Haro River. This important Buddhist establishment was for the first time excavated by Sir John Marshall in 1930-31. Field investigations at the site were resumed in 2012-13 by the Department of Archaeology, Hazara University (Mansehra), in collaboration with the Directorate of A...
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Ancient steppes for human equestrians The Eurasian steppes reach from the Ukraine in Europe to Mongolia and China. Over the past 5000 years, these flat grasslands were thought to be the route for the ebb and flow of migrant humans, their horses, and their languages. de Barros Damgaard et al. probed whole-genome sequences from the remains of 74 indi...
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Bhamala, one of the most important Buddhist establishments is located on the right bank of the Hero river in the Khanpur region of Taxila Valley. Recent Excavations at the site have brought to light many remarkable discoveries, which include the earliest monumental Parinirvana statue of the Buddha, the terracotta sculptures, coins and other metal o...
Article
Full-text available
Bhamala, one of the most important Buddhist establishment is located on the right bank of the Hero river in the Khanpur region of Taxila Valley. Recent Excavations at the site have brought to light many remarkable discoveries, which include the earliest monumental Parinirvana statue of the Buddha, the terracotta sculptures, coins and other metal ob...
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The article presents a catalogue of the numismatic material collected during the excavation at Bhamala, Taxila/Haro valley carried out by the Directorate of Archaeology and Museums, Government of Khyber-Pakhtunkhwa and Department of Archaeology, Hazara University Mansehra, from 2014 to 2017. This catalogue completes and updates the previous data fr...
Article
Begomoviruses (family Geminiviridae) are responsible for extreme yield reduction in a number of economically important crops including medicinal and aromatic plants (MAPs). Emergence of new variants of viruses due to recombination and mutations in the genomes, modern cropping systems, introduction of susceptible plant varieties, global trade in agr...
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Whitefly-transmitted begomovirus induces leaf curling and stunting of Mentha arvensis (Kosi) and is responsible for heavy economic losses in and around Lucknow, India. The complete genome was amplified, sequenced and assembled as 2759 bp long, with 1376 bp betasatellite molecule. Because no DNA-B amplicon was detected, the virus was classified as “...
Article
Full-text available
The World Heritage site of Bhamala is located on the right bank of the Haro River. This important Buddhist establishment was for the first time excavated by Sir John Marshall in 1930-31. Field investigations at the site were resumed in 2012-13 by the Department of Archaeology, Hazara University (Mansehra), in collaboration with the Directorate of A...
Article
Essential oil of Mentha spicata L. var. viridis 'Ganga', an indigenously developed variety, was chemically profiled using various gas chromatographic techniques. Piperitenone oxide was characterized as the most exclusive constituent (69.7%) along with a new C³-oxygenated p-menthane alcohol, diosphenolene (1.6%). Enantiomeric discrimination revealed...
Article
Uraria picta (Prishniparni) is a perennial leguminous medicinal herb, distributed across tropical Africa and Asia, including India, Sri Lanka, and Malay Islands. The flavonoid content of U. picta imparts antithrombotic, anti-inflammatory, and hepato-protective activities (Kale et al. 2012). During August 2013, a new fungal disease was observed on t...
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Andrographolide and neoandrographolide are major bioactive molecules of Andrographis paniculata, a well-known medicinal plant. These molecules exhibited varying degrees of anti-inflammatory and anticancer activities in-vitro and in-vivo. Role of begomovirus protein C2/TrAP in biosynthesis of andrographolide was identified through molecular modeling...
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Begomoviruses infect a wide range of plant species and are emerging as one of the most detrimental pathogens. Recombination has led to the evolution and emergence of new species of begomoviruses that are better adapted to new hosts. With the development of computational recombination detection programs, better detection methods and increased availa...
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The infection of Eclipta yellow vein virus [EcYVV-IN, Accession No. KC476655], recently reported for the first time, on Andrographis paniculata was studied for redox-mediated alteration mechanism in infected plants. A. paniculata, an important medicinal plant, is used in traditional Indian, Chinese and modern system of medicine. Andrographolide, on...
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Damask Rose (Rosa damascena; Family Rosaceace) is one of the most expensive essential oil bearing crop of many countries including India. A previously undescribed “Rose witches'-broom” infestation was detected and exhibited symptoms of little leaf, apical proliferation and chlorosis during winter season in the experimental farms of CSIR-CIMAP, Luck...
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Clary sage (Salvia sclarea L.) is an industrial crop grown for its high value essential oil, widely used in perfumery and cosmetic industries. In the present work, agromorphological characteristics, essential oil content and composition and randomly amplified polymorphic DNA (RAPD) markers were studied to estimate the relationships among 11 clary s...
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Current study aims to explore natural anti-phytopathogenic compounds for plant disease management. Syzygium cumini essential oil and its isolated compounds were screened for their antifungal assay against two phytopathogenic fungi, Rhizoctonia solani AG 4HG-III and Choanephora cucurbitarum. The chemical composition of isolated oil was identified by...
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Sweet basil (Ocimum basilicum), a member of the Lamiaceae, is used as an ornamental as well as a culinary herb. It is a rich source of the phenolic compound methyl chavicol and is used as a traditional medicinal plant in India, where the crop is grown on ~2,500 ha annually (4). The species is native to India, where it has been cultivated for >5,000...
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We have investigated in vitro antifungal efficiency of nitrogen doped carbon nanohorn (NCNH) against Rhizoctonia solani (R. solani) plant pathogenic fungi. NCNH with size of 50-60 nm and concentrations of 10, 50, 100 and 150µg mL-1 were used. The results showed that growth of fungi in the presence of NCNH was significantly (p>0.05) inhibited at 150...
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Andrographis paniculata (Family Acanthaceae), also called Kalmegh, is a medicinal herb in India well-known for its various pharmaceutical properties (1). In August 2012, during a survey in the northern parts of India, several Kalmegh plants in Barabanki District of Uttar Pradesh Province showed typical virus-like symptoms along with prominent letha...
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Beta-site APP cleaving enzyme1 (BACE1) catalyzes the rate determining step in the generation of Aβ peptide and is widely considered as a potential therapeutic drug target for Alzheimer’s disease (AD). Active site of BACE1 contains catalytic aspartic (Asp) dyad and flap. Asp dyad cleaves the substrate amyloid precursor protein with the help of flap....
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Andrographis paniculata (family Acanthaceae), also known as “King of Bitters” or Kalmegh, is an important medicinal plant used for the treatment of various diseases. It has antimicrobial, antiviral, anti-inflammatory, hepatoprotective, antidiabetic, antihyperglycemic, and antioxidant properties (1). During June 2014, while performing a routine surv...
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Menthofuran is an aromatic organic compound that naturally occurs in oil extracted from flower buds of Mentha piperita, making a major contribution to the aroma of the oil. The menthofuran content of Indian peppermint varieties varies from 5 to 12 %, with the exception of cv. CIM-Indus that has a methofuran content of as high as 25 %. The demand fo...
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A novel strain of Pseudomonas monteilii, PsF84 was isolated from tannery waste soil, Jajmau, Kanpur, India. 16S rRNA gene sequence phylogenetic analysis confirmed the taxonomic affiliation of PsF84 as P. monteilii. An antifungal volatile organic compound (VOC) was active against hyphal growth of Fusarium oxysporum (CIMAP-IMI-357464) in vitro was is...
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Geminiviruses are ssDNA viruses that infect a wide range of plant species. Andrographis paniculata (family Acanthaceae), an herb commonly known as Kalmegh, is famous for its medicinal properties such as anti-inflammatory, antibiotic, antimalarial, anticancerous, antidiabetic, antihepatotoxic, antioxidant, and is helpful in curing various diseases (...
Article
Opium poppy (Papaver somniferum L.) of the family Papaveraceae is cultivated in different parts of the world such as Tasmania, Afghanistan, Egypt, India and Pakistan for the production of pharmaceutically important alkaloids including morphine, codeine, thebaine and papaverine. These alkaloids are frequently used as an analgesic, anti-tussive and a...
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Artemisia anuua L. (Quinghao; Family Asteraceae) is a natural source of a potent anti-malarial drug artemisinin. Salt stress inhibits its growth; seed germination is the most sensitive and crucial stage of its life cycle. Sodium chloride tolerance during germination is important for establishment of plants that grow in saline habitats. The objectiv...
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1-Hydroxyphenazine (1-OH-PHZ), a natural product from Pseudomonas aeruginosa strain SD12, was earlier reported to have potent antifungal activity against Rhizoctonia solani. In the present work, the antifungal activity of 1-OH-PHZ on 40S ribosomal S9 protein was validated by molecular docking approach. 1-OH-PHZ showed interaction with two polar con...
Article
Mint (Mentha spp.; family Lamiaceae) is an important essential oil-bearing crop cultivated on the Indian subcontinent as a cash crop for the international market and industrial purposes. Since May 2010, typical symptoms such as yellow vein, leaf yellowing, mosaic, crinkling, and cupping were observed, which led to significant yield loss in spearmin...
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The Mexican marigold (Tagetes erecta) is cultivated commercially in India for medicinal, ceremonial, and decorative purposes. It is native to Mexico and the United States. The natural phytochemical thiophene extracted from T. erecta has been shown to have antibacterial activity. It is also grown to extract lutein, a common yellow/orange food color....
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A new strain of Streptomyces was isolated from heavy metal polluted soil of industrial (tannery) area of Jajmau, Kanpur, India. The strain was designated as Streptomyces sp. CIMAP A2 based on cultural, morphological and physiological studies. Further, molecular characterization of the strain was carried out based on sequencing 1520 bp fragment of 1...
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A bacterial strain, Streptomyces sp. CIMAP- A1 was isolated from Geranium rhizosphere and identified by morphological, physiological, biochemical and molecular characters (16S rDNA gene sequence). Phylogenetically, it was found most closely related to S. vinacendrappus, strain NRRL-2363 with 99% sequence similarity. The strain had potential antagon...
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A new strain, SD12, was isolated from tannery waste polluted soil and identified as Pseudomonas aeruginosa on the basis of phenotypic traits and by comparison of 16S rRNA sequences. This bacterium exhibited broad-spectrum antagonistic activity against phytopathogenic fungi. The strain produced phosphatases, cellulases, proteases, pectinases, and HC...
Article
High-throughput analysis of a large number of samples for pharmacokinetic study is necessary in drug development and pharmacovigilance. Usually, drug quantification for pharmacokinetics and bio-availability is achieved through matrix extraction and HPLC analysis, which is time, labour and cost intensive method. A prompt and solvent free method is t...
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Full-text available
A new strain, SD12, was isolated from tannery waste polluted soil and identified as Pseudomonas aeruginosa on the basis of phenotypic traits and by comparison of 16S rRNA sequences. This bacterium exhibited broad-spectrum antagonistic activity against phytopathogenic fungi. The strain produced phosphatases, cellulases, proteases, pectinases, and HC...
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The present article presents the results of a recent (2009) survey of understandings and attitudes to heritage and culture in Chitral, Pakistan. Chitral has two main ethnic-religious groups: the Muslim Kho and the Kalasha, who are the largest non-Muslim minority group in the Hindu Kush. Very little is known formally of Chitral history and prehistor...
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Stevia rebaudiana Bertoni (Asteraceae) is one of the most important commercial crops in the world (4). It is known to produce glycosides that are up to 300 times sweeter than sucrose and do not affect blood sugar levels. Unlike artificial sweeteners like saccharin, they are non-carcinogenic and safe for diabetics. An unknown disease emerged during...
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A new severe little leaf disease was observed on P. grandiflora, popular as Moss-rose Purslane, widely grown in temperate zones. Characteristic symptoms, ultrastructural studies, antibiotic response and amplification of 16S ribosomal DNA fragments (about 1.5 kb) by polymerase chain reaction (PCR) from infected samples, suspect the involvement of ph...
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A new disease of Trachyspermum ammi, commonly known as Ajwain in India, was observed in Lucknow, India. The symptoms included small chlorotic leaves, highly proliferating shoots, witches’ broom appearance, shortened internodes and an overall stunted growth. Poor flower heads and fruit setting caused considerable yield losses for farmers. In transmi...
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We have used apical meristem culture to develop an efficient protocol for reducing phytoplasma infection of Artemisia roxburghiana Besser var. purpurascens (Jacq.) Hook. plants. Shoot tips of different sizes from phytoplasma-infected field-grown plants were treated with 0.1% mercuric chloride (HgCl2) for 1min followed by a 30-s exposure to 70% etha...
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Mung bean is an important source of food for humans and animals in tropical and subtropical countries, and is also used for green manure. During spring 2008, mung bean plants in Faisalabad, Pakistan, showed severe symptoms of phyllody, virescence and a bushy appearance. Stem, leaf and stalk phloem sections from plants with and without symptoms were...
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cv. Viridis at CIMAP, Lucknow, and in adjoining areas theoccurrence of a begomovirus-caused disease was for the first time observedduring May and June 2005. Typical symptoms were foliar rugosity, lightyellow mosaic, upward curling, crinkling and retarded growth leading todrastic reduction in the herb’s yield. In 2007, the disease incidence wasrecord...
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Portulaca grandiflora (family Portulacaceae), commonly known as moss rose purslane, is a popular ornamental plant widely grown in temperate climates because it blooms all summer. Portulaca is also used for medicinal purposes since it is rich in vitamins A, B1, and C and has antimicrobial and cytotoxic activity. Since March 2005, 30 to 50% of P. gra...
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This paper reports the characterisation of a naturally occurring Cucumber mosaic virus (CMV) infection, causing mosaic, leaf distortion and stunting of periwinkle (Catharanthus roseus). The virus isolate showed wide host range, biophysical properties similar to CMV, isometric particles of 28 nm, capsid protein of 26 kDa, serological reaction with C...