Abdul Mujib

Abdul Mujib
Jamia Hamdard (Deemed to be University) · Botany

Ph.D

About

114
Publications
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Introduction
Dr. A. Mujib, DAAD fellow (Germany), Dept. of Botany, SCLS, Jamia Hamdard, New Delhi; M.Sc; Ph. D, Univ. of Kalyani, W.B; Formerly Research Associate and Mission Engineer, Dept. of Chemical Eng, IIT, Kharagpur. Research fields plant biotech, embryogenesis, proteomics, gene expression; mutagenesis, chromosome, molecular- flow cytometric analyses, biotic-abiotic elicitation. Published 160 articles; supervised 18 Ph. Ds; on editorial board of 45 Journals; reviewing articles for 85 Journals.

Publications

Publications (114)
Article
Full-text available
The present study investigated the impact of gamma ray irradiation on callus biomass growth and the yield of vincristine and vinblastine of in vitro grown tissues of Catharanthus roseus. The biochemical alteration underlying the synthesis of secondary metabolites has also been studied and a comparison of yield was prepared. The embryogenic tissues...
Article
Full-text available
Tylophora indica (Burm.f.) Merrill. is a pharmacologically important plant, popular for alkaloidal and non-alkaloidal richness. Large scale propagation of T. indica is difficult in the wild as the seeds are small and the frequency of germination is very poor. In the present study, the genome size estimation of in vitro regenerated (indirect, direct...
Article
Full-text available
An efficacious and reproducible in vitro regeneration technique for safflower was established using varying concentrations and composition of plant growth regulators (PGRs) supplemented Murashige and Skoog (MS) medium. Successful in vitro seed germination in half strength MS (H-MS) with 1.4 µM GA3 resulted in procurement of sterile explants (cotyle...
Chapter
The asexual, non-zygotic (somatic) embryogenesis was reported over 60 years ago. It is a unique process in which somatic cell transforms into embryo in cultured condition affirming cellular totipotency. Since its first report, somatic embryogenesis has been noted in different plant genera of a dicot, monocot, and lower fern groups. In the present c...
Chapter
Somatic or in vitro embryogenesis is a unique embryo producing process from vegetative cells observed in plants since 1958. Even over 60 years of research, the transition of somatic cells into embryonic fate is still not elucidated fully. Various networks and signaling elements have been noted to play important role in this "vegetative to reproduct...
Article
Full-text available
Caladium × hortulanum 'Fancy' is an important ornamental plant grown in pots and landscapes and known for its colorful leaves often used for interior decorations. In this work, we present a method of in vitro regeneration from three explants source through direct somatic embryogenesis (DSE) wherein the regenerated plants were screened for ploidy ch...
Article
Somatic embryogenesis is an important and wonderful biotechnological tool used to develop whole plant from a single or a group of somatic cells. The differentiated somatic cells become totipotent stem cells by drastic reprogramming of a wide range of cellular activities, leading to the acquisition of embryogenic competence. After acquiring competen...
Article
Full-text available
Genus Zephyranthes consists of economically important plant species due to their high ornamental value and presence of valuable bioactive compounds. However, this genus propagates by asexual division only which gives slow propagation rate. Plant tissue culture has the potential to provide efficient techniques for rapid multiplication and genetic im...
Article
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Background: Somatic embryogenesis (SE) is an intricate molecular and biochemical process principally based on cellular totipotency and a model in studying plant development. In this unique embryo-forming process, the vegetative cells acquire embryogenic competence under cellular stress conditions. The stress caused by plant growth regulators (PGRs...
Article
Plant cell tissue and organ culture techniques provide an efficient way for the biosynthesis of high-value secondary metabolites in which elicitation has been recognized to be a potent approach in enriching the bioactive compounds. In this study, an effort was made to assess the influence of Cadmium chloride (CdCl 2) on alliin yield of different in...
Article
Various strategies have been developed globally to conserve germplasm by propagating plants. One important technique is in vitro propagation and preservation through tissue culture. In many investigated plants, the long in vitro conservation is plagued with several limitations like genetic variations, developmental errors in cells or tissues due to...
Chapter
Synthetic seed technology has been successfully employed in various medicinal and ornamental plants. It has immense potential in preserving callus, somatic embryo (SE), and other important tissues of valuable germplasm. The method can also be exploited as a tool of multiplication in diverse plant groups. Synthetic seed production in plants facilita...
Article
In vitro cultures play a promising role for production of pharmaceutically important plant secondary metabolites and the use of elicitation can mitigate the low productivity of active compounds. In the present study, the influence of cadmium chloride (CdCl2) elicitation on alkaloid yield was investigated in Rauvolfia serpentina. This heavy metal wa...
Research
analyses of genome size of tissue cultured and field grown plants.
Article
In the present study, an efficient in vitro propagation protocol has been developed from clove explants of Allium sativum L., one of the oldest vegetable and medicinal plant used worldwide. Garlic is propagated vegetatively as cross-fertilization is strictly precluded due to sterile flowers. Due to a low rate of multiplication, limited genetic impr...
Chapter
Plant tissue culture (PTC) has immensely contributed in the field of science for the last 100 years, particularly, in the latter half of the 20th century after the discovery of somatic embryogenesis and other associated findings/techniques. The technique is highly reliable in taping the economic potentials of medicinal and crop plants. PTC also pla...
Article
Full-text available
In the present study, the induction of callus, callus biomass growth and the yield of taxol were investigated in Taxus wallichiana. This is the first report of a quantification study of taxol in in vitro grown tissues of Taxus obtained from Jammu and Kashmir provinces, India. For callus induction, three different explant types (leaf, cone and stem)...
Article
Coriandrum sativum is an important spice plant known for its unique fragrance. Coriander oil is also one of the major essential oils in world global market. The oil yield varies with different coriander varieties; and the content and quality of oil is governed by several factors. In recent times, a variety of technologies have been exploited to imp...
Article
Full-text available
Somatic embryogenesis (SE) is an intricate in vitro multi-step biotechnological tool used to develop embryos/plants from a single or a group of somatic cells. It is a model technique for understanding various plant developmental pathways. A lot of research is going on to elucidate the mechanism underlying the process of SE. This study was aimed at...
Article
Full-text available
An efficient and reproducible protocol for plant regeneration from protoplasts has been developed in two Coriandrum sativum varieties – Co-1 and Rajendraswathi (RS). The RS coriander is rich in oil and shows resistance to diseases whereas Co-1 is known for better yield. In the present study, protoplast isolation – the first step of fusion was under...
Article
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The plant extracts of Catharanthus roseus L. (G). Don has been used in alternate medicine for years, but the curing mechanism of these extracts is still not scientifically elucidated. The purpose of this study was to examine the effect of in vitro and ex vitro cultivated plant extracts in protecting the model rat against diethyl nitrosamine (DEN) i...
Article
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Meet Our Editorial Board Member Abdul Mujib Hamdard University (Jamia Hamdard) New Delhi, India Dr. Abdul Mujib is a Ph.D, a DAAD fellow (Germany), now associated with the Department of Botany, Hamdard University, New Delhi, India. He received his M.Sc. and Ph. D degree from the University of Kalyani, W.B (India). He was appointed and served earlie...
Article
Full-text available
The biotechnological approach of exploiting cell culture elicitation (amendment) offers an attractive alternative strategy to overcome the limited availability of biologically active and medicinally important secondary metabolites. The present study investigated the influence of abiotic aluminum chloride (AlCl3) elicitation on alkaloid yield in Rau...
Article
Full-text available
Catharanthus roseus (L.) G. Don, Apocynaceae, is an immensely important medicinal plant, produces a variety of anticancerous compounds. The yield of two most investigated alkaloids vinblastine and vincristine is unfortunately very low. A vast array of technologies including elicitation have recently been used to enrich Catharanthus alkaloid in cult...
Article
Full-text available
The plant extracts of Catharanthus roseus L. (G). Don has been used in alternate medicine for years, but the curing mechanism of these extracts is still not scientifically elucidated. The purpose of this study was to examine the effect of in vitro and ex vitro cultivated plant extracts in protecting the model rat against diethyl nitrosamine (DEN) i...
Chapter
Full-text available
Catharanthus roseus (L.) G. Don is an important plant of medicinal importance. A number of active compounds of this plant are anti-cancerous in nature. Two such compounds are vinblastine and vincristine; unfortunately, the level of these phytocompounds is very low. In this chapter, the influence of elicitation, one of the important biotechnological...
Article
Full-text available
In the present study, an improved plant regeneration protocol via primary and secondary somatic embryogenesis was established in two Co-1 and Rajendra Swathi (RS) varieties of Coriandrum sativum L. Callus was induced from root explants on 2, 4-D (0.5-2.0 mg/l) supplemented MS. The addition of BA (0.2 mg/l) improved callus induction and proliferatio...
Article
Gladiolus is a valuable asexually propagated plant of horticultural importance. Here, in the present communication, in vitro embryogenesis protocol and 2C DNA content of embryo regenerated plant are described. Callus was first induced from corms on 2, 4. D and NAA + BAP amended MS medium and the frequency was maximum (75.12%) in 0.5 mg/l NAA + 0.5...
Article
Full-text available
Althaea officinalis L. (marshmallow) belonging to the Malvaceae family, is an important plant that contains a variety of important phytocompounds including asparagine, pectin, flavonoids, polyphenolic acid, and scopoletin. The yield of these compounds can be improved using biotechnological methods that allow for a steady and continuous regeneration...
Chapter
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Climbing plants are groups of plants that often show unique horticultural uses because of their beauty-imparting features. As the stems are weak, these plants have evolved various climbing devices in order to support growth and development. This climbing habit is predominantly seen in angiosperms and some members of ferns, and Gnetum is the only re...
Article
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The influence of fungus elicitor Aspergillus flavus on alkaloid yield was investigated in Catharanthus roseus. The study reveals increased yield of vinblastine and vincristine in cultivated tissues. Different concentrations of extract applied to solid MS medium were: 0.05 % (T1), 0.15 % (T2), 0.25 % (T3), and 0.35 % (T4) along with control (T0). Th...
Chapter
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The process of in vitro embryogenesis has several basic and applied applications especially in fast and mass propagation of elite ornamental germplasm. In this chapter, somatic embryogenesis is described in two important ornamental plants. The select plants Gladiolus and Caladium are the monocot genera, belonging to the family Iridaceae and Araceae...
Book
Somatic embryogenesis (SE) is a unique process by means of which a vegetative/somatic plant cell transforms into an embryo. This in vitro embryogeny has immense fundamental and practical applications. The SE process is complex and is controlled by a variety of external and internal triggers. This book compiles the latest advances in embryogenesis r...
Article
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Since the first report on Camptothecin detection in Nothapodytes nimmoniana by Govindachari and Viswanathan (Phytochem 11:35–29, 1972), considerable work has been done on biotechnology and its applications on the species. Plant tissue culture techniques have applications in clonal propagation, CPT production, and conservation of N. nimmoniana. Disc...
Article
Full-text available
An improved synthesis of vinblastine and vincristine was observed in Catharanthus roseus L. (G). Don by using NaCl as an elicitor. Various in vitro grown embryogenic tissues were cultivated under salinity stress for enhanced synthesis of alkaloids. Different levels of salt [control (0 mM), NT1 (25 mM), NT2 (50 mM), NT3 (75 mM), NT4 (100 mM), and NT...
Article
Full-text available
An efficient somatic embryo encapsulation and in vitro plant regeneration technique were established with Caladium bicolor, an important ornamental plant. Tuber derived embryogenic callus (95.50%) was obtained on Murashige and Skoog (MS) medium amended with 0.5 mg L-1 α-Naphthalene acetic acid (NAA) + 0.5 mg L-1 6-Benzyladenine (BA). The embryogeni...
Article
Full-text available
An efficient somatic embryo encapsulation and in vitro plant regeneration technique were established with Caladium bicolor, an important ornamental plant.Tuber derived embryogenic callus (95.50%) was obtained on Murashige and Skoog (MS) medium amended with 0.5 mg L-1 α-Naphthalene acetic acid (NAA) + 0.5 mg L-1 6-Benzyladenine (BA). The embryogenic...
Article
Full-text available
Nothapodytes nimmoniana is an endangered medicinal tree and regarded most convenient natural source for large scale isolation of anticancer alkaloid camptothecin. In order to meet pharmaceutical market demand for camptothecin and conserve natural population of the species, in vitro culture techniques can be employed for mass propagation and product...
Article
Full-text available
The purpose of this study was to evaluate and compare the use of liquid and solid Murashige and Skoog (MS) medium in different culture vessels for mass production of Catharanthus roseus, an important source of anticancerous compounds, vincristine and vinblastine. Three media conditions i.e. agar-solidified medium (S), liquid medium in agitated coni...
Article
Full-text available
Catharanthus roseus (L.) G. Don is an important medicinal plant as it contains several anti-cancerous compounds, like vinblastine and vincristine. Plant tissue culture technology (organogenesis and embryogenesis) has currently been used in fast mass propagating raw materials for secondary metabolite synthesis. In this present communication, scannin...
Article
Full-text available
Catharanthus roseus (L.) G. Don is an important medicinal plant as it contains several anti-cancerous compounds, like vinblastine and vincristine. Plant tissue culture technology (organogenesis and embryogenesis) has currently been used in fast mass propagating raw materials for secondary metabolite synthesis. In this present communication, scannin...
Article
Full-text available
Coriandrum sativum L. is an annual herb belonging to the family Umbelliferae. It is used as a spice plant in Indian subcontinent and it has several medicinal applications as well. In this present article, an efficient plant regeneration protocol from protoplasts via somatic embryogenesis was established and is reported. This is the first ever proto...
Article
Full-text available
The genus Zephyranthes rosea is a member of the family Amaryllidaceae. The plant is widely cultivated as ornamental. The objective of this study was to optimize an in vitro propagation method for the production of genetically stable Z. rosea plant. The chromosomal status of the regenerated plants was also studied to determine their ploidy levels an...
Article
Full-text available
Nothapodytes nimmoniana is an endemic endangered tree and convenient source for large scale isolation of anticancer alkaloid camptothecin. Due to indiscriminate collection of its wood chips for camptothecin, population of the species is under heavy exploitation pressure in India. Plant tissue culture techniques offer alternative strategies for clon...
Article
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An efficient system for plant regeneration of Senna occidentalis from hypocotyl-derived callus was developed. Callus was induced from leaf and hypocotyl explants on MS medium amended with 9.04 μM 2,4-D + 2.22 μM BAP and 10.74 μM NAA + 2.22 μM BAP. Medium browning due to leaching of compounds from callus was encountered and ameliorated through incor...
Article
Full-text available
Somatic embryogenesis has been employed in various basic and applied studies such as cellular differentiation of plants, generating transgenic en masse and for mass propagation of elite, endangered and ornamental plants. The studies undertaken in some monocot genera (Eucharis, Hippeastrum, Crinum, Caladium, Gloriosa and Allium) suggest that in vitr...
Article
Full-text available
A protocol has been developed for in vitro plant regeneration from a nodal explant of Dracaena sanderiana Sander ex Mast. Nodal explant showed high callus induction potentiality on MS medium supplemented with 6.78 μM 2,4-dichlorophenoxyacetic acid (2,4-D) followed by 46.5 μM chlorophenoxy acetic acid (CPA). The highest frequency of shoot regenerati...
Article
Full-text available
Omamentals are important groups of plants in plant kingdom. Conventionally, these groups of plants propagate vegetatively. During the last few decades plant tissue culture method has been used successfully for commercial production of a wide range of economic and elite plants including omamentals. Although the in vitro technology assures true-to-ty...
Chapter
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Secondary metabolites are mainly derived from plants and are used by humans from time immemorial. A plant cell, tissue, and organ culture has an inherent capacity to manufacture valuable chemical compounds as the parent plant does in nature. In vitro plant materials are one of the good sources for the production of secondary metabolite and elicitat...
Chapter
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Soil salinity is one of the most important problems worldwide, which has decreased crop production to a great extent. The major or deleterious effects of salinity on plant growth and development are associated with low osmotic potential of soil solution, nutritional imbalance etc. Consequently these can ultimately lead to plant death because of gro...
Chapter
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Medicinal and aromatic plants contribute to a variety of resources that play an imperative role in the human sustenance and eradication of human sufferings. Medicinal plants have been subjugated both in an organized (Ayurvedic, Unani) and unorganized (folk, tribal and native) form. However, over-exploitation during changeover from traditional to mo...
Article
Full-text available
Somatic embryogenesis has been employed in various basic and applied studies such as cellular differentiation of plants, generating transgenic en masse and for mass propagation of elite, endangered and ornamental plants. The stud-ies undertaken in some monocot genera (Eucharis, Hippeastrum, Crinum, Caladium, Gloriosa and Allium) suggest that in vit...
Article
Full-text available
An in vitro method to improve the production of vincristine (VCR) was developed by using CaCl2 elicitor in embryogenic suspension culture of C. roseus. CaCl2 at various levels [0 mM (T0), 5 mM (T1), 25 mM (T2), 50 mM (T3), 75 mM (T4) and 100 mM (T5)] was added in MS medium as an elicitor molecule. Cultural growth in terms of absolute dry mass, pack...
Article
Full-text available
Garlic, an important flavoring agent and a medicinally useful plant, can take up selenium from its immediate surrounding medium and incorporate it at high concentrations into amino acids and phytochemicals. Selenium, supplied as 0.5, 1.0, 2.0, and 4.0 mg L−1 Na2SeO3 increased the amino acid, protein, proline, and alliin content of in vitro-grown ca...