Abdelmalik Belkhiri

University of Constantine 3 · Pharmacy, faculty of medicine

Aim. The present study was carried out to evaluate the wound healing potential of crude Hydroalcoholic fruit extracts of Grape ( Vitis vinifera L.) and Pomegranate ( Punica granatum L.) in experimental animals. Material and methods. Extracts were formulated as ointments (250 mg), and their wound healing properties were determined by using two model...

The current study shows the research on phytochemical concerning the phenolic components of Algerian pomegranate fruit extract (Punica granatum L.) using Ultra Performance Liquid Chromatography Diode-Array Detection Electrospray Ionization Mass Spectrometry (UPLC-DAD-ESI-MS). In this study; about more than 50 phenolic compounds, including 40 phenol...

Varroa destructor is an external parasitic mite that is a serious pest of honeybees and has caused severe losses of colonies worldwide. One of the feasible alternative treatments being used for their control is the application of essential oils, which are generally inexpensive and most pose few health risks. The investigation was designed to determ...

In this study we discuss Mentha pulegium shoot multiplication and the capacity of in vitro plants to produce essential oils (EOs). EO was obtained by hydrodistillation from dried leaves and flowering stems of in vitro and field-grown plants, and their chemical composition was examined by GC-MS. The differences in yield as well as quantitative and q...

Four edible fruits from Vitis vinifera, Punica granatum, Citrus aurantium and Opuntia ficus indica from Algeria were analyzed in order to determine the total polyphenol, total flavonoid and flavonol contents using classical spectrophotometric methods. The antioxidant activity was established by three different single-electron-transfer-based assays...

Introduction. The alcohol extract of Pellitory ( Anacyclus pyrethrum ) roots has been previously shown to exert anticancer activities on the Human Colorectal Cancer Cell Line (HCT) by targeting apoptosis, metastasis and cell cycle arrest. However, the nature of the cytotoxic molecules associated with this activity remains unexplored. Aims . This st...

Mentha rotundifolia (L.) Huds is an aromatic plant used for its medicinal values. This study aims to select appropriate conditions for in vitro propagation of M. rotundifolia (L.) Huds and to evaluate yield and antioxidants activity of its essential oils (EOs). The explants were cultured on Murashige and Skoog (MS) medium containing different conce...

The study was aimed at determining the chemical composition, toxicity effect and field varroacidal efficacy of the essential oil distilled from the leaf of Eucalyptus globulus (Eg) grown in Algeria. Brine shrimp lethality (BSL) assay and bee hives infected by Varroa destructor were used to assess the toxicity and acaricidal effect, respectively. St...

The objective of this research was to determine the chemical composition, evaluate toxicity and acaricidal effect of essential oil of Eucalyptus robusta to control Varroa destructor of bees. Essential oilof Eucalyptus robusta (E. robusta) was extracted from fresh leaves by steam distillation using a Clevenger apparatus and was analysed by chromatog...

A detailed study was performed on the antioxidant activity of the alcoholic extract of different plant parts of Cleome Arabica ssp. arabica (CAA) in relation with their total phenolic, flavonoid and proanthocyanidins contents in order to find possible sources for future novel antioxidants in food and pharmaceutical formulations. The total yield, to...

Purpose: To investigate the analgesic properties of hydro-alcohol fruit extracts of Vitis vinifera (grape) and Punica granatum (pomegranate) in albino male mice. Methods: The analgesic activity of the fruit extracts was examined in vivo using thermal stimulus assays (tail immersion and hot plate) and chemically-induced writhing test. The extracts w...

Purpose: To investigate the analgesic properties of fruit extracts of Vitis vinifera (grape) and Punica granatum (pomegranate) in Albino mal mice. Methods: The analgesic activity of fruit extracts of V. vinifera and P. granatum were examined in vivo using thermal stimulus assays (i.e., tail immersion and hot plate) and acetic acid-induced writhing...

The aim of this study was to determine the chemical characterization and to assess full-thickness-excised wound-healing activity of the oil of Pistacia lentiscus L. fruits grown in Algeria. The fatty acid composition of P. lentiscus L. extracts were analyzed by GC–MS and their total protein amounts were determined by elemental analysis. Total thick...

The current study was undertaken to evaluate in vitro the antileishmanial activity of three plants growing wild in Algeria : Juglans regia, Lawsonia inermis and Salvia officinalis. The hydroalcoholic extracts of these plants were tested on the growth of the promastigotes of Leishmania major. The plant extract effects were compared with three contro...

Skin wound healing is a complex and dynamic process involving a sequence of integrated events including inflammation, granulation tissue formation, matrix deposition and remodeling [1, 2]. The search for natural compounds which can stimulate tissue repair has gained importance in the recent years aiming the development of non-toxic formulations for...

Opuntia ficus indica and Pistacia lentiscus L. seeds are used in traditional medicine. The objective of this study was to investigate the toxicity of the fixed oil of Opuntia ficus indica and Pistacia lentiscus L. seeds in mice through determination of LD50 values, and also the physicochemical characteristics of the fixed oil of these oils. The acu...

Pistacia lentiscus fatty oil (PLFO) is a well known natural remedy in eastern Algeria folk medicine. It is widely used in the treatment of respiratory disorders and dermal burns. The present study has been carried out to investigate effects of this oil on fasting glucose and some functional parameters of the liver and kidney in white male New Zeala...

Several natural products have been shown to accelerate wound healing process. The present study was undertaken to evaluate the effect of Pistacia lentiscus fruits fatty oil on cutaneous wound healing in rat, and to compare this effect to that of saponifiable and unsaponifiable oily fractions. Full-thickness excision wounds were made on the back of...