Abdelazeem Algammal

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Abdelazeem verified their affiliation via an institutional email.

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• Full Professor, Ph.D
• Professor and Head of Department at Suez Canal University

Background: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods:...

Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territor...

Proteus mirabilis is a common opportunistic pathogen causing severe illness in humans and animals. To determine the prevalence, antibiogram, bioflm-formation, screening of virulence, and antimicrobial resistance genes in P. mirabilis isolates from ducks; 240 samples were obtained from apparently healthy and diseased ducks from private farms in Port...

Methicillin-resistant Staphylococcus aureus (MRSA) is a major human pathogen and a historically emergent zoonotic pathogen with public health and veterinary importance. In humans, MRSA commonly causes severe infectious diseases, including food poisoning, pyogenic endocarditis, suppurative pneumonia, otitis media, osteomyelitis, and pyogenic infecti...

Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for several difficult-to-treat infections and staphylococcal food poisoning (SFP). This study was conducted to investigate the prevalence and en- terotoxigenicity of MRSA in broiler chicken meat and giblets. A total of 5.5% (8/144) of the examined samples were contaminated with mecA...

This is the supplementary information for the paper "Characterising Acute and Chronic Care Needs: Insights from the Global Burden of Disease Study 2019" published in Nature Communications. The document provides complementary study results, presented as supplementary figures and tables. The list of contributors is also included.

Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global B...

Neurological disorders have been the leading cause of global health loss, yet the neurological burden in China remains poorly understood. Researchers in this study comprehensively examined the distribution and trends of burden due to neurological disorders in China and its provinces. They found that neurological disorders extensively affected the C...

Although iron deficiency is well documented, less is known about dietary involvement in symptomatic iron deficiency manifesting in medical conditions. In this study, we quantified the global burden of dietary iron deficiency, focusing on where inadequate dietary iron intake leads to clinical manifestations such as anemia. We analyzed data from the...

Although iron deficiency is well documented, less is known about dietary involvement in symptomatic iron deficiency manifesting in medical conditions. In this study, we quantified the global burden of dietary iron deficiency, focusing on where inadequate dietary iron intake leads to clinical manifestations such as anemia. We analyzed data from the...

Background and Aim: The human gut microbiome plays a crucial role in maintaining health. Artificial sweeteners, also known as non-nutritive sweeteners (NNS), have garnered attention for their potential to disrupt the balance of the gut microbiome. This review explores the complex relationship between NNS and the gut microbiome, highlighting their p...

The transmission of aflatoxins from fish products to consumers primarily occurs through the contamination of fish flesh and feed by aflatoxigenic fungi. This study comprehensively examined the prevalence and extent of fungal contamination in the flesh of Oreochromis niloticus and Mugil cephalus, as well as in fish feed. Furthermore, it assessed the...

Background Bovine mastitis caused by Staphylococcus aureus is considered a public health threat globally. Herein, we aimed to investigate the occurrence, agr typing, antimicrobial resistance patterns, biofilm production, and PCR-based detection of the virulence, biofilm, adhesion, and enterotoxins genes of S. aureus strains recovered from clinical...

Background and aim Brevundimonas spp. are ubiquitous in the environment, but they are infrequently isolated from clinical specimens. Brevundimonas spp. cause bacteremia and sepsis, less frequently pneumonia, which resist numerous antibiotics, such as fluoroquinolone and beta lactams. The aim of this study was to investigate the epidemiological dist...

Summary Background: Overweight and obesity is a global epidemic. Forecasting future trajectories of the epidemic is crucial for providing an evidence base for policy change. In this study, we examine the historical trends of the global, regional, and national prevalence of adult overweight and obesity from 1990 to 2021 and forecast the future traje...

The coral microbiome is highly related to the overall health and the survival and proliferation of coral reefs. The Red Sea’s unique physiochemical characteristics, such a significant north–south temperature and salinity gradient, make it a very intriguing research system. However, the Red Sea is rather isolated, with a very diversified ecosystem r...

Background Despite the well documented consequences of obesity during childhood and adolescence and future risks of excess body mass on non-communicable diseases in adulthood, coordinated global action on excess body mass in early life is still insufficient. Inconsistent measurement and reporting are a barrier to specific targets, resource allocati...

Background Overweight and obesity is a global epidemic. Forecasting future trajectories of the epidemic is crucial for providing an evidence base for policy change. In this study, we examine the historical trends of the global, regional, and national prevalence of adult overweight and obesity from 1990 to 2021 and forecast the future trajectories t...

Summary Background Epilepsy is one of the most common serious neurological disorders and affects individuals of all ages across the globe. The aim of this study is to provide estimates of the epilepsy burden on the global, regional, and national levels for 1990–2021. Methods Using well established Global Burden of Diseases, Injuries, and Risk Facto...

Supplement to: GBD Epilepsy Collaborators. Global, regional, and national burden of epilepsy, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Public Health 2025; published online Feb 24. https://doi.org/10.1016/ S2468-2667(24)00302-5

Supplement to: GBD Epilepsy Collaborators. Global, regional, and national burden of epilepsy, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Public Health 2025; published online Feb 24. https://doi.org/10.1016/ S2468-2667(24)00302-5

Background: Decades of steady improvements in life expectancy in Europe slowed down from around 2011, well before the COVID-19 pandemic, for reasons which remain disputed. We aimed to assess how changes in risk factors and cause-specific death rates in different European countries related to changes in life expectancy in those countries before and...

Pasteurella multocida is incriminated in fowl cholera in poultry and snuffles in rabbits, causing significant economic losses in the poultry industry worldwide. This study investigated the prevalence, kmt1 gene sequencing, antibiogram, pathogenicity, and PCR detection of the virulence and resistance genes of P. multocida recovered from chickens, du...

Vibrio alginolyticus is associated with severe infections in marine fish and immunocompromised people. This study investigated the prevalence, genetic typing, associated virulence traits, unveiling resistance genes, and the pathogenicity of V. alginolyticus isolated from sea bream. A total of 200 sea bream (Sparus aurata) were gathered from seclude...

Background Klebsiella pneumoniae is a significant nosocomial pathogen that has developed resistance to multiple antibiotics, often forming biofilms that enhance its virulence. This study investigated the efficacy of a novel nanoformulation, AgNPs@chitosan-NaF, in combating K. pneumoniae biofilms. Methods Antimicrobial susceptibility testing was pe...

The coral microbiome is highly related to the overall health and the survival and proliferation of coral reefs. As the Red Sea's unique physiochemical characteristics, such a significant north-south temperature and salinity gradient, make it a very intriguing research system. However, the Red Sea is rather isolated, with a very diversified ecosyste...

The aquaculture sector has recently shown increasing interest in novel natural molecules as components of eco-friendly, safe, and antibiotic-free diets. The metabolic itaconate molecule, known for its antioxidant, anti-inflammatory, and immunomodulatory properties, has emerged as a promising candidate. However, limited research exists on the specif...

Summary Background Diarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age groups of children younger than 5 years are scarce, and the burden in children older than 5 years and in adults is also un...

Background The capacity to anticipate future health issues is important for both policy makers and practitioners in the USA, as such insights can facilitate effective planning, investment, and implementation strategies. Forecasting trends in disease and injury burden is not only crucial for policy makers but also garners substantial interest from...

In recent years, the global health landscape has been marked by the resurgence of infectious diseases that were once considered under control. Among these viruses, Monkeypox (Mpox), a zoonotic virus from the Orthopoxvirus genus, has emerged as a significant public health concern. Originally confined to central and western African regions, this zoon...

Nanomaterials such as selenium nanoparticles (SeNPs) are commonly used in everyday products and offer numerous health benefits to aquatic animals. Vitamin C (Vit C) is an essential micronutrient for fish because of its strong antioxidant properties. However, the combined effects of SeNPs and Vit C on enhancing disease resistance in Nile tilapia (Or...

Background Over the past several decades, the overweight and obesity epidemic in the USA has resulted in a significant health and economic burden. Understanding current trends and future trajectories at both national and state levels is crucial for assessing the success of existing interventions and informing future health policy changes. We esti...

Methods appendix to: GBD 2021 US Obesity Forecasting Collaborators. National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050. Lancet 2024; published online Nov 14. https://doi.org/10.1016/S0140-6736(24)01548-4. This appendix formed part of the origin...

Supplementary appendix 2. Results appendix to: GBD 2021 US Obesity Forecasting Collaborators. National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050. Lancet 2024; published online Nov 14. https://doi.org/10.1016/S0140-6736(24)01548-4 This appendix...

Background Stillbirth is a devastating and often avoidable adverse pregnancy outcome. Monitoring stillbirth levels and trends—in a comprehensive manner that leaves no one uncounted—is imperative for continuing progress in pregnancy loss reduction. This analysis, completed as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (G...

Background: The widespread use of antimicrobials in agriculture, coupled with bioactive chemicals like pesticides and growth promoting agents, has accelerated the global crisis of antimicrobial resistance (AMR). Agroecosystems provides a platform in the evolution and dissemination of antibiotic-resistant bacteria (ARB) and antibiotic resistance gen...

Supplement to: GBD 2021 Tobacco Forecasting Collaborators. Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021.Lancet Public Health 2024; 9: e729–44. Appendix 3: Authorship appendix to “Forecasting the effects of smokin...

Background : Smoking is the leading behavioural risk factor for mortality globally, accounting for more than 175 million deaths and nearly 4·30 billion years of life lost (YLLs) from 1990 to 2021. The pace of decline in smoking prevalence has slowed in recent years for many countries, and although strategies have recently been proposed to achieve t...

Since the last century, antibiotics have been our re- liable weapons against infectious diseases. In addition to their medicinal applications in human and veterinary medicine, antibiotics are also used in agriculture. How- ever, the uncontrolled usage of antibiotics has led to the emergence of drug-resistant microbial strains and the rise of their...

Vibrio parahaemolyticus is associated with severe food-borne illness in humans as well as substantial financial setbacks in the fishing sector. To investigate the prevalence, pathogenicity, virulence, as well as the resistance patterns of V. parahaemolyticus retrieved from Oreochromis niloticus, 180 O. niloticus (moribund fish; n = 120 and apparent...

Aeromonas veronii, a threatening fish pathogen, is implicated in food-borne infections in humans, contributing to substantial economic losses in the aquaculture sector. To examine the occurrence, resistance profiles, 16SrRNA sequence analysis, virulence-determinant and resistance genes, and pathogenicity of A. veronii isolated from Nile tilapia (Or...

Enterobacter cloacae is regarded as a hazardous fish pathogen that causes severe diseases and major economic losses in the fish industry. In this study, 150 Mullet species, including 70 Mugil cephalus and 80 Mugil capito were collected randomly from Lake Temsah in Ismailia Governorate, Egypt during the period from May 2022 to July 2022. Subsequentl...

Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditio...

Background Recently, lipase processing for biodiesel production has shown a global increase as it is considered a potential alternative clean-fuel source. The current study’s objective is to investigate of lipolytic activity of lipase produced from different strains of Pseudomonas aeruginosa (P. aeruginosa) in biodiesel production using edible plan...

Background Bacillus cereus is implicated in severe foodborne infection in humans. This study intended to assess the occurrence, groEL gene sequencing, biofilm production, and resistance profiles of emerged multidrug resistant (MDR) B. cereus in meat and meat product samples. Moreover, this work highlights the virulence and toxigenic genes (hblAB...

Background

Background and aim: This study aimed to detect New Delhi metallo-beta-lactamase 1(NDM-1) harboring Moraxella lacunata and Sphingomonas paucimobilis for the firsttime in Iraq. Material and methods: One hundred and sixty-nine bacterial isolates were collectedfrom blood samples in Baghdad children hospital. Two bacterial species based on the selectio...

Environmental pollution is a serious problem that can cause sicknesses, fatality, and biological contaminants such as bacteria, which can trigger allergic reactions and infectious illnesses. There is also evidence that environmental pollutants can have an impact on the gut microbiome and contribute to the development of various mental health and me...

Gallibacterium anatis (G. anatis), a member of the Pasteurellaceae family, normally inhabits the upper respiratory and lower genital tracts of poultry. However, under certain circumstances of immunosuppression, co-infection (especially with Escherichia coli or Mycoplasma), or various stressors, G. anatis caused respiratory, reproductive, and system...

Avian salmonellosis is concomitant with high financial crises in the poultry industry as well as food-borne illness in man. The present study is designed to investigate the emergence of Salmonella Enteritidis and Salmonella Typhimu-rium in diseased broilers, resistance profiles, and monitoring virulence and antibiotic resistance genes. Consequently...

KEYWORDS innate immunity, adaptive immunity, human urinary system, nervous system, interleukins, toll-like receptors, cytokines

Marine pollution and bacterial disease outbreaks are two closely related dilemmas that impact marine fish production from fisheries and mariculture. Oil, heavy metals, agrochemicals, sewage, medical wastes, plastics, algal blooms, atmospheric pollutants, mariculture-related pollutants, as well as thermal and noise pollution are the most threatening...

Background and aim: In early December 2019 started coronavirus disease 2019 (COVID-19) pandemic in China by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection which transmitted from bats to humans. According to WHO, there are more than two hundred million confirmed cases of COVID-19 including more than seven million deaths, so w...

Background and aim Binary copper-cobalt oxide nanoparticles (CuO\CoO NPs) are modern kinds of antimicrobials, which may get a lot of interest in clinical application. This study aimed to detect the effect of the binary CuO\CoO NPs on the expression of papC and fimH genes in multidrug-resistant (MDR) isolates of Klebsiella oxytoca to reduce medicati...

The similarity of the Listeria innocua genome with Listeria monocytogenes and their presence in the same niche may facilitate gene transfer between them. A better understanding of the mechanisms responsible for bacterial virulence requires an in-depth knowledge of the genetic characteristics of these bacteria. In this context, draft whole genome se...

Background The function of different populations of the immune system in bladder cancer (BCa) is well established. However, the cohesive role of the immune cell profile of schistosomal BCa at systemic and tissue levels is still lacking, especially in endemic countries. The balance hypothesized between protumorigenic and antitumor molecules determin...

Poultry feathers are rich with keratin protein and so represent environmental pollutant due to contamination with different microbes. The goal of this study is to recycle feather wastes and decrease pollutants using graphene-based material mixed with keratinase enzyme, which is purified from bacteria isolated from slaughterhouses. Fifteen isolates...

Background Pseudomonas aeruginosa is incriminated in septicemia, significant economic losses in the poultry production sector, and severe respiratory infections in humans. This study aimed to investigate the occurrence, oprL sequencing, antimicrobial resistance patterns, virulence-determinant, Quorum sensing, and antibiotic resistance genes of P. a...

The concern of antimicrobial resistance (AMR) is considered to feature among the to threats to global health (World Health Organization, 2019, 2022). Several issues are recognized as relevant etiologic factors in the emergence of AMR, including worldwide misuse or overuse of antibiotics. According to recorded reports, low- and middle-income countri...

Tenacibaculosis occurs due to the marine bacterial pathogen Tenacibaculum maritimum. This ulcerative disease causes high mortalities for various marine fish species worldwide. Several external clinical signs can arise, including mouth erosion, epidermal ulcers, fin necrosis, and tail rot. Research in the last 15 years has advanced knowledge on the...

The coronavirus disease 2019 (COVID-19) pandemic has prompted a lot of questions globally regarding the range of information about the virus’s possible routes of transmission, diagnostics, and therapeutic tools. Worldwide studies have pointed out the importance of monitoring and early surveillance techniques based on the identification of viral RNA...

Staphylococcus aureus is one of the most common causes of mastitis, leading to severe economic losses in the dairy industry. It is also zoonotic, with potential risks to public health. This study aimed to detect the occurrence of S. aureus-resistant strains isolated from cattle, buffalo, their environment, milk and dairy products; and to investigat...

The emergence of pathogens conferring resistance to last-resort therapies like tigecycline, colistin, and carbapenems limiting the therapeutic options and raising concerns about the emergence of new "superbugs". The current study reports the first incident of a blaNDM-5 and tet(X4) co-harboring E. coli with resistance to carbapenem and tigecycline...

Aeromonas veronii is associated with substantial economic losses in the fish industry and with food-borne illness in humans. This study aimed to determine the prevalence, antibiogram profiles, sequence analysis, virulence and antimicrobial resistance genes, and pathogenicity of A. veronii recovered from Mugil seheli. A total of 80 fish were randoml...