Abdallah Hussien Fathy

Abdallah Hussien Fathy
Ain Shams University · Laboratory Animal Facility

PhD

About

19
Publications
130,845
Reads
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46
Citations
Citations since 2016
18 Research Items
46 Citations
201620172018201920202021202202468101214
201620172018201920202021202202468101214
201620172018201920202021202202468101214
201620172018201920202021202202468101214
Introduction
Dr. Fathy completed his Ph.D. at the Faculty of Science, Al Azhar University. He is working as Laboratory Animal Facility Managing Director at Faculty of Pharmacy Ain Shams University. His research experiences are in radiotherapy and radiation toxicity, chemotherapy, hepatocellular carcinoma, carcinogenesis, drug-induced toxicity, and assessment of medicinal plant constituents as well as novel synthetic organic compounds. He is also a member of some national committees.

Publications

Publications (19)
Conference Paper
Full-text available
The present study was designed to determine the possible protective effects of the olive oil (7 g/kg) with fig (1 g/kg) and date-palm fruit (1 g/kg) extracts (OFD) against the toxicity hazards of doxorubicin (DOX) which was used as chemotherapy of cancer and/or γ-radiation which was used as radiotherapy of cancer. The DOX-treated groups were inject...
Article
Full-text available
Hepatocellular carcinoma (HCC) is one of the most life-threatening cancers. The present study was designed to chronologically analyze the HCC chemically induced by diethylnitrosamine (DEN) in male Wistar rats during 27 weeks. DEN was given to rats in drinking water (100 mg/L) to induce HCC. In the present study, the DEN administered groups recorded...
Article
Full-text available
Abstract | Chemotherapy and radiotherapy are among the traditional methods used in cancer treatment and they cause toxicity to normal cells. The purpose of the present study is to determine the possible hepatoprotective role of olive oil (7 g/kg) with fig (1 g/kg) and date-palm fruit (1 g/kg) extracts (OFD) together as potent antioxidants in allevi...
Article
Full-text available
Abstract Diethylnitrosamine (DEN) is a well-known carcinogen. The aim of our study was to determine the role of olive oil (7 g/kg) with fig (1 g/kg) (OF) and (or) date palm (1 g/kg) (D) fruit extracts during DEN treatment of male Wistar rats. The OF–DEN and (or) D–DEN groups were given oral antioxidants daily for two weeks before and during DEN tre...
Article
Full-text available
The goal of this study was to determine the possible beneficial effect of olive oil (7 g/kg) with fig (1 g/kg) and date palm fruit (1 g/kg) extracts (OFD) on the toxicity hazards of doxorubicin (DOX) and (or) γ-radiation. The DOX-treated groups received doses of 2.5 mg/kg body weight via intravenous (IV) injection weekly for four consecutive weeks....
Poster
Full-text available
Certificate Elsevier Reviewer Recognition
Poster
Full-text available
Certificate for Publons Peer Review Award
Data
ReviewerCertificate
Data
Selected JCR Year: 2017 Selected Editions: SCIE,SSCI Selected Category Scheme: WoS
Preprint
Diethylnitrosamine (DEN) is a well-known carcinogen. The aim of the present study is to determine the role of olive oil (7 g/kg) with fig (1 g/kg) (OF) and/or date-palm (1 g/kg) (D) fruit extracts during DEN administration to male Wistar rats. The OF-DEN and/or D-DEN treated groups received the antioxidant treatments orally and daily for 2 weeks be...
Data
The natural antioxidant plant materials used in the present study were the extra-virgin olive oil obtained from the fruit of the olive tree (Olea europaea L.; Family Oleaceae), dried ripe fruit of fig (Ficus carica L.; Family Moraceae) and date-palm fruit (phoenix dactylifera L.; Family Arecaceae). We purchased the extra-virgin olive oil from the G...
Preprint
The present study is an endeavor to explore the beneficial effects of olive oil as well as fig and date palm extracts (OFD) as natural antioxidants against hepatocellular carcinoma (HCC) proliferation in rats treated with doxorubicin (DOX) and/or gamma radiation (R). Rats were given diethylnitrosamine (DENA, 100 mg/L) in drinking water to induce ad...
Preprint
The aim of the present study is to determine the possible protective effects of fig with olive oil (FO) and/or dates (D) during diethylnitrosamine (DEN) administration to rats. The FO groups were administered with fig extract (1 g/kg body weight) and olive oil (7.6 ml/kg body weight) via oral gavage for 23 weeks. The D treated groups were treated w...
Preprint
Manuscript number JEP_2017_1805 Title Protective effect of extra virgin olive oil with fig and date palm extracts against diethylnitrosamine-induced hepatocarcinogenesis in male Wistar albino rats for 23 weeks Article type Research Paper Abstract Ethnopharmacological relevance: The extra virgin olive oil, ripe dried fruits of Ficus carica Linn. (Mo...
Article
Full-text available
The present study was designed to determine the possible protective and therapeutic effects of olive oil, Ficus carica and both against radiation-induced oxidative stress and biochemical changes in liver of albino rats. A patch of 114 male Wister albino rats averaged weights 120±5 g at the beginning of the experiment were distributed into 8 main gr...

Questions

Questions (78)
Question
Public opinion on the morality of animal research is on the downswing in the United States. But some researchers think letting the public know more about how animals are used in experiments might turn things around. Online News Editor David Grimm joins Sarah Crespi to talk about these efforts.
Question
The patients weren't crazy—Knut Lundin was sure of that. But their ailment was a mystery. They were convinced gluten was making them sick. Yet they didn't have celiac disease, an autoimmune reaction to that often-villainized tangle of proteins in wheat, barley, and rye. And they tested negative for a wheat allergy. They occupied a medical no man's land.

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Projects

Projects (4)
Project
One of the approaches to protect the liver is by prophylaxis. In the present project, We testing the possible synergistic action of some natural antioxidants against HCC in male Wistar rat model for 23 weeks
Project
​- Sequential analysis of chemically-induced hepatocarcinogenesis in Wistar rat model during 27 weeks. - Establishing evidence-based novel staging system of HCC with more than 40 parameters. - Assessment of different stages of HCC (early, intermediate, advanced, and late stages). - Excellent model for testing anticancer drugs at various stages of hepatocarcinogenesis. - Testing chemopreventive and chemotherapeutic antioxidants.
Project
Revealing the possible synergistic action of the extra-virgin olive oil with fig and date-palm fruit extracts against the toxicity hazards of doxorubicin and ionizing radiation