Abbas Afkhami

Abbas Afkhami
Buali Sina University · Faculity of Chemistry

About

429
Publications
63,770
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
14,184
Citations
Citations since 2016
159 Research Items
9187 Citations
201620172018201920202021202205001,0001,500
201620172018201920202021202205001,0001,500
201620172018201920202021202205001,0001,500
201620172018201920202021202205001,0001,500

Publications

Publications (429)
Book
Full-text available
Analytical Nanochemistry: How Nanotechnology and Analytical Chemistry Impact Each Other explains the fundamental information needed to understand and utilize nanomaterials, including their classification, synthesis, functionalization, characterization methods, separation and isolation techniques, and toxicity. In addition, it covers fundamental inf...
Article
Full-text available
Despite the presence of light-sensitive species in the polyol synthesis of silver nanocubes, the influence of light on it has yet to be investigated. Herein, we demonstrated that light radiation, by generating plasmon-based hot electrons and subsequently increasing the reduction rate of Ag⁺ in the system, in addition to enhancing the growth rate of...
Article
To investigate heteroatom-doped carbon nitride (C3N4) materials as supports, Au nanoparticles anchored on sulfur-doped carbon nitride nanosheets ([email protected]) was prepared and used as a catalyst for arsenic electroreduction. Novel SCNN was synthesized for the first time via a simple thermally induced copolymerization route using ammonium pers...
Article
While the detection of tryptophan enantiomers is of great importance in the field of pharmacy and biotechnology, significant limitations exist in their selective determination using conventional methods. A simple solution is to use immunochromatographic assays, thereby separating enantiomers and detecting them by electrochemical methods. In this st...
Article
Heavy metals determination is of great importance. In this respect, a recently synthesized melamine-based covalent organic framework (Schiff base network1 (SNW1)) was used in this research as a novel modifier to alter a glassy carbon electrode for the simultaneous anodic stripping square wave voltammetric measurement of Pb²⁺ and Hg²⁺ ions. At first...
Article
Metal-organic frameworks (MOFs) have previously been researched for electrochemical sensor development. MOFs are commonly stated to have low conductivity, and improving their conductivity remains a significant challenge. We described the preparation of an electrochemical sensor depending on the in situ growth of NiCo-BTC bimetallic MOFs, as model b...
Article
Full-text available
A novel low-cost method for simultaneous measurement of Cd²⁺ and Pb²⁺ is proposed. In this method, the surface of the glassy carbon electrode (GCE) was modified with multi-walled carbon nanotubes (MWCNTs) and poly(thionine) (PTH), afterward, Pb2+ and Cd2+ were measured simultaneously in the presence of bismuth ions in-situ, using square wave anodic...
Article
Full-text available
Exposure to air pollutants has been linked to the exacerbation of the respiratory disease. The air quality index and air quality health index (AQHI) were used to evaluate the number of asthma hospitalization attributed to air quality using time-series regression analysis with a distributed lag model. This study was performed from March 2014 to Febr...
Article
The lack of simple strategies for the design and fabrication of electrochromic (EC) sensors has obstructed the extensive application of these efficient devices in analytical chemistry. Herein, we introduced a novel EC sensor based on the proton sensitivity of conducting polyaniline (PANI) film to determine amines as a model analyte. Firstly, the EC...
Article
In this research, a highly sensitive electrochemical sensor was developed for the square wave anodic stripping voltammetric determination of Pb2+ at ultra-trace levels. A Glassy carbon electrode was modified with an in-situ electroplated bismuth film and the nanocomposite of a recently synthesized melamine based covalent organic framework (schiff b...
Article
Hollow polymer nanospheres (HPSs) were prepared based on the feeble acid–base interaction-induced assembly in hydrothermal conditions. It was first used as a sorbent in microextraction by packed sorbent method for the separation of the major biomarkers of BTEXs in urine samples. Fourier-transform infrared spectroscopy, X-ray diffraction, scanning,...
Article
In this study, a magnetic covalent organic framework (MCOF) was synthesized using a novel and simple solution method to explore its potential as a magnetic adsorbent for dye removal. The synthesis of MCOF was confirmed using different techniques and data demonstrated that the as-prepared nanoparticles were 21–46 nm in diameter. The MCOF, before and...
Article
Full-text available
Phosphorylation of PI3Kγ as a member of lipid kinases-enzymes, plays a crucial role in regulating immune cells through the generation of intracellular signals. Deregulation of this pathway is involved in several tumors. In this research, diverse sets of potent and selective isoform-specific PI3Kγ inhibitors whose drug-likeness was confirmed based o...
Article
Prussian blue analogues (PBA) and their derived materials are intriguing for energy storage platforms due to the intrinsic open framework, tunable composition, low cost, and easy preparation. In recent years, current research has focused on improving their conductivity and energy storage. In this paper, cobalt-manganese Prussian blue analogues (PBA...
Article
A relatively new adsorbent based on covalent organic frameworks (COFs) was employed for the first time to extract and determine Trans, trans-muconic acid (tt-MA), Mandelic acid (MA), Hippuric acid (HA), and 3-Methylhippuric acid (m-MHA) in urine. For this purpose, microextraction was performed using the packed sorbent (MEPS) method. Following the e...
Article
Developing new ultrasensitive assays for the detection of the presence, and determination of the serotype of the most poisonous material known i.e. botulinum neurotoxin (BoNT) is vital to human health and to the wellbeing of the surrounding environment. Here, an electrochemical sandwich immunoassay with high sensitivity is adopted to achieve simult...
Chapter
Nanostructure semiconductor materials with remarkable properties have attracted intense attention in device applications, like electronic devices, photovoltaic solar cell technologies, light-emitting diodes, energy storage devices, field-effect transistors, sensors, etc. The semiconductors possess a band gap lying between that of metals and insulat...
Chapter
Engineering conductive polymers (CPs) onto separation and extraction devices is a promising topic for future research in modern analytical chemistry. This chapter investigates current trends in the characteristics and uses of CPs in the separation stage of study. CPs can provide a variety of opportunities and possibilities for manufacturing novel s...
Chapter
Conductive polymers (CPs), also known as synthetic metals, have been the focus of enormous interest in the research community. In recent years, they have been used in myriad applications due to their intrinsic properties, including good electrical conductivity, flexibility, easy preparation, mechanical strength, biocompatibility, and low cost. Toda...
Chapter
Miniaturization is a general concept addressing the trend of manufacturing small and smaller mechanical, optical, and electronic products and devices. Today, this trend has gained a high interest of researchers of engineering, medicine, materials science, physics, chemistry, and computer science. An analytical process consists of six general steps...
Chapter
Spectroscopy methods, as the basic analytical instrumentation methods, are employed in different sciences. They have a wide range of applications in chemistry. Small spectrometers are divided into laboratory portable instruments, field analyzers, and process analyzers. Miniaturized spectroscopic instruments are one class of portable spectrometers....
Chapter
Recent advances in miniaturized sensing devices have led to the design of integrated analytical devices such as biosensors and sensors. Nowadays, miniaturized sensors are highly desired for real-time and fast-response measurements in clinical diagnostics. This chapter discusses different categories of lab-on-a-chip devices based on the application...
Chapter
Separation instruments including gas chromatography, high pressure/performance liquid chromatography, capillary electrophoresis, and ion chromatography have become a part of most of the analytical laboratories. These methods are primarily used for the separation of complex samples and quantitation of a target analyte in the sample. Some of these in...
Chapter
With the rapid development of sensors and biosensors and the advent of smartphones, smartphone-based sensing systems have emerged as new devices for detecting various analytes. These devices take advantage of both the high sensitivity of sensors and biosensors and the variety of functions of smartphones, which can be considered as fast, low-cost, a...
Chapter
The increasing advancement in the micro/nanofabrication process has made it possible and facile to miniaturize expensive complex benchtop instruments to create instruments as small as regular cellphones with the ability to perform experiments in the field without special training. The electrochemical biosensors can be miniaturized to portable bioel...
Article
Full-text available
The iontophoresis delivery of insulin (INS) remains a serious challenge due to the low permeability of the drug through the skin. This work aims to investigate the potential of water-soluble polypyrrole nanoparticles (WS-PPyNPs) as a drug donor matrix for controlled transdermal iontophoresis of INS. WS-PPyNPs have been prepared via a simple chemica...
Article
This paper introduced needle traps filled with the new Schiff base network-1/single-walled carbon nanotube (SNW-1/SWCNT) adsorbent for sampling and analyzing phenolic compounds (phenol, 3-chlorophenol, o-cresol, and p-cresol) in air. In this perusal, the SNW-1/SWCNT adsorbent was synthesized and packaged using a 22-gauge spinal needle. This approac...
Article
Full-text available
Air pollutants are the most important environmental factors that contributed to cardiovascular disease (CVD). The present study aimed to investigate the number of hospitalization due to heart failure (HF) and myocardial infarction (MI) following the air pollutant exposure using a time-series regression analysis with a distributed lag model in Hamad...
Article
Full-text available
Metal−organic frameworks (MOFs) have received extensive attention in adsorption applications owing to their high surface area. However, some MOFs do not perform well as the extraction medium when used under aqueous conditions. The low hydrostability of MOFs limits the practical application of these materials in solid-phase microextraction (SPME). H...
Article
Beta-blockers (β-blockers) are a special type of medicine that are prescribed for a wide range of health problems including cardiovascular diseases. There is a narrow border between the therapeutic and toxic levels of β-blockers and at high dosages. β-blockers can cause serious side effects. Besides, β-blockers are used as a doping agent at some sp...
Article
New magnetic molecularly imprinted polymers (mag-MIP) were developed for 1-Aminopyrene (1-Ap) detection in human urine samples. 1-Ap is a biomarker for exposure to the 1-Nitropyrenes (as a mutagenic compound) present in the particles emitted from various sources mainly the diesel engines. Fe3O4 (as a magnetic core), TEOS, 1-Ap (as a template), MAA...
Article
Developing sensitive strategies to detect the biomarkers is responsible for early detection of a genetic disorder and cancer-related biomarkers. Herein, a rational design of high catalytic activity of artificial enzyme mimics with enhancing the robustness of functional nanozymes has been introduced to detect PSA as a model target. Using a separatio...
Article
A sandwich-type electrochemical immunoassay was introduced for the determination of the prostate-specific antigen (PSA) biomarker. A direct and simple galvanic replacement reaction was performed between the Ag framework and metallic salts of tetrachloroauric(iii) acid trihydrate and chloroplatinic acid to produce a trimetallic composite of AgAuPt....
Article
Achieving efficient chiral discrimination by a convenient method remains a challenge in pharmaceutical and biotechnology industries. Our aim in this paper was to develop a dual-signaling enantioselective sensing strategy based on the competitive binding assay. A combination of β-cyclodextrin (β-CD) and methylene blue (MB) was used as an enantiosele...
Article
The development of preconcentration methods in the design of electrochemical sensors is attractive due to the lack of efficient strategy for the preconcentration of organic analytes. Herein, we described the employment of electropolymerization as a novel preconcentration approach in the electrochemical determination of melamine (Mel). In this effor...
Article
Full-text available
This study aims to develop a promising electrochemical sensor based on polymer film overoxidation following the electrochemical polymerization of p-aminophenol on a bare glassy carbon electrode (GCE) surface for the voltammetric determination of sumatriptan succinate (SUM). Cyclic voltammetry (CV), Fourier-transform infrared spectroscopy (FT-IR), s...
Book
Magnetic Nanomaterials in Analytical Chemistry provides readers with the first comprehensive review of magnetic nanomaterials in a variety of Analytical Chemistry applications. Magnetic nanomaterials that can be controlled using external magnetic fields have opened new doors for the development of new sample preparation methods. They have attracted...
Article
A polymer dot modified histidine-functionalized graphene quantum dot carrier, [email protected], was synthesized to investigate the in vitro sunitinib (STB) delivery via luminescence spectrometer. The carrier’s synthesis, with an average size of 34 nm, was proved by Fourier transform infrared (FTIR), Transmission Electron Microscopy (TEM), and Dyna...
Article
A new subset of furan-pyrazole piperidine derivatives was used for QSAR model development. These compounds exhibit good Akt1 inhibitory activity; moreover, antiproliferative activities in vitro against OVCAR-8 (Human ovarian carcinoma cells) and HCT116 (human colon cancer cells), were confirmed for them. Based on the relevant three-dimensional (3D)...
Chapter
Due to their superparamagnetism property as well as the high surface-to-volume ratios, magnetic nanomaterials (MNMs) have been utilized as both sorbents and sensors in analytical chemistry. Different aspects of the application of MNMs in analytical chemistry have widely been reviewed. However, the application of MNMs in the magnetic field sensors h...
Chapter
Today, the development of fast and reliable methods for providing quantitative information is an ongoing need in analytical chemistry. Taking advantage of both nanoscale size and magnetic manipulability, magnetic nanomaterials (MNMs) have found a wide range of applications in different fields from chemistry to biomedicine. MNMs also have been utili...
Article
The dose of administered chemotherapy drugs is crucial to determine due to the potential for efficient or adverse outcomes for cancer patients. To date, no user-friendly and low-cost method of doxorubicin (DOX) detection using nontoxic and biodegradable materials has been reported. For this reason, in this work, we have developed for the first time...
Article
Full-text available
The increasing efforts devoted to fabricating electrochromic (EC) devices have motivated a lot of studies to develop new EC materials. Herein, we introduce two poly(phenothiazine)-type redox active polymer films as new EC materials. Poly(methylene blue) (PMB) and poly(thionine) (PTH) films were electrochemically deposited onto the transparent fluor...
Article
Solid-phase microextraction (SPME) is extensively employed in analytical chemistry to improve extraction efficiency. The development of SMPE methods is still a great challenge thanks to its poor selectivity. Herein, we have reported the application of electrochemically controlled solid-phase microextraction (EC-SPME) based on a conducting molecular...
Article
In an overview, the relationships between activity, property, and chemical structure of the anthracycline derivatives, as topoisomerase II enzyme inhibitors, were studied in pairs. These analogs were investigated in three categories with known half-maximal inhibitory concentration (IC50), known octanol/water partition coefficient (logP), and both I...
Article
Full-text available
The construction of graphene-based microfibers with reinforced mechanical and electrical properties has been the subject of numerous researches in recent years. However, the fabrication of graphene-based fibers with remarkable optical features still remains a challenge and has not been addressed so far. This paper aims to report a series of flexibl...
Article
Full-text available
In the present study, both gaseous and particulate (PM with dae <2.5 µm) phases of polycyclic aromatic hydrocarbons (PAHs) were measured in the ambient air of Hamadan city, Iran. For this reason, two low-volume samplers equipped with glass fiber filters were used for sampling of particulate phase (N = 30) and XAD-2 sorbent tubes were applied for sa...
Article
Conductive polymers (CPs) have been previously investigated as active redox material for developing electrically controlled drug release. These systems usually suffer from their low drug loading capacity which is a great challenge in drug delivery systems. Here, we offered the fabrication of electrically controlled drug release based on the one-ste...
Article
Magnetic nanomaterials (MNMs) have gained high attention in different fields of studies due to their ferromagnetic/superparamagnetic properties and their low toxicity and high biocompatibility. MNMs contain magnetic elements such as iron and nickel in metallic, bimetallic, metal oxide, and mixed metal oxide. In electroanalytical methods, MNMs have...
Article
Magnetic solid-phase extraction (MSPE) coupled with the spectrophotometric method for the simultaneous quantification of aluminum and beryllium ions based on mean centering of ratio (MCR) method is reported in the current work, for the first time. Two new magnetic ion-imprinted polymers (MIIPs) were synthesized using Chrome Azurol S as the ligand,...
Article
A comprehensive study on anthracycline derivatives was done. A quantitative structure–activity relationship (QSAR) study on the half-maximal inhibitory concentration (IC50) of these analogs was developed. These antitumor compounds are used as topoisomerase II enzyme inhibitors. Genetic algorithm (GA) was applied for feature extraction. Multiple lin...
Article
Hybrid spectroelectrochemical sensors (HSESs) have been introduced in recent years to improve the analytical performance of chemical sensors. The development of these methods is still a serious challenge due to the lack of efficient electrochemical stimulation strategy. In this research, we have reported the development of an HSES based on the elec...
Article
This paper reports on the development of an extraction method called “ultrasound-assisted dispersive liquid antisolvent precipitation (UA-DLAP)”. The developed method is a combination of dispersive liquid-liquid microextraction (DLLME) and liquid antisolvent precipitation (LAP) methods. Unlike DLLME, the extraction solvent in UA-DLAP is replaced wi...
Article
This work presents an effective strategy for the well-oriented immobilization of antibodies in which boronic acid is directly attached to the surface and with no need of the long and flexible spacer. A magnetic graphene nanoribbon-boronic acid-based immunosensor was developed and tested for the impedimetric detection of lymphoma cancer cells, a blo...
Article
In this paper, we have presented the syntheses feasible scheme for reliable and suitable construction, using a two-step hydrothermal/ grinding method, [email protected]2/UiO-66-NH2 (gAT/U6N) composites. The photocatalytic efficiency was calculated by the elimination of Rhodamine B (RhB) by visible light radiation. Consequently, the optimized (AT30-...
Article
Nickel zinc ferrite (Ni0.5Zn0.5Fe2O4) nanoparticles decorated poly (vinyl alcohol) was constructed by the electrospinning method and used for determining the sunitinib amount in real sample. In this study, resonance light scattering (RLS) technique was used for studying the interaction of nanofibers with sunitinib. Similar Ni0.5Zn0.5Fe2O4 nanoparti...
Article
Nowadays, environmental pollution is one of the major worldwide problems. There are various types of pollutants (i.e., organic, inorganic, and biological materials), which can contaminant water resources, land, and air. Therefore, there is a high demand to develop and design new devices for the detection and determination of various contaminants in...
Article
Dopamine β-hydroxylase (DBH) is involved in various neuronal transmission processes in the brain. Due to the severe diseases caused by abnormity levels of such important enzyme in human serum, sensitive and rapid detection of DBH at early stages is crucial, particularly for clinical analysis. Herein, we developed optical sensors for DBH that includ...
Article
Significant levels of infectious diseases caused by pathogenic bacteria are nowadays a worldwide concern implying considerable public healthcare challenges and huge economic detriment. Due to the fast spread of these bio-threat agents and the outbreak of diseases, a rapid detection of pathogens at early stages is crucial, particularly in low-resourc...
Article
Nickel–zinc ferrite (Ni0.5Zn0.5Fe2O4) nanosorbent was prepared and used for the efficient simultaneous preconcentration of arsenite and arsenate ions from aqueous solutions. The prepared nanoparticles were characterized by XRD measurements which indicated that the Ni0.5Zn0.5Fe2O4 nanoparticles were synthesized well. The SEM results showed an averag...