University of Cape Coast
Question
Asked 23 December 2018
What are the procedures of Paternity and Maternity testing? Are they 100% correct?
Paternity testing is matching paternal DNA and maternity testing is matching of Mitochondrial DNA.
Is it so?
How these tests are performed?
What are the other tests available?
Are they 100% effective to confirm paternity or maternity?
Most recent answer
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Popular answers (1)
Gruppo Ricerca Geriatrica, Genova, Italy
Paternity/maternity tests are performed when it is necessary to determine the biological origin of a child.
The test is based on the fact that each person inherits half of their DNA molecules (chromosomes) from their mother, and half – from their father. In order to determine the biological origin of a child, the profiles of DNA molecules of the possible father, the child, and the mother are compared. The DNA profile (STR genotype) is almost unique for each person, since the probability that two males who are not blood relatives might have an identical DNA profile is extremely low. This property of DNA profiles is also used in the paternity test in order to determine the biological origin of a child.
The accuracy of the paternity test is directly proportional to the number of DNA regions (loci) to be tested. In recent history, DNA profiles with 10 DNA loci were compared in paternity tests in Latvia. Today, a DNA profile in which at least 15 DNA loci are compared in samples of a man, a child and a woman is recognised as the best method for proving paternity. Already for the second year GenEra laboratory compares results in 24 loci.The loci to be analysed are determined by international forensic institutions, therefore today almost all laboratories test the same set of loci and the results are often compatible.
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All Answers (30)
University of Yaoundé I
A paternity test is not currently 100 percent accurate. With a DNA percentage test, the result, which is deemed the “probability of parentage,” is 0 percent when the alleged father of the baby is not biologically related. The result is typically 99.99 percent when the alleged father of the baby is biologically related to the child. Very rare individuals may have two separate sets of genes, also known as chimeras, as opposed to a single distinct set, which can result in a false positive test.
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Consultant Pathologist and Transfusion Medicine Specialist to Patankar Pathology, Laha Diagnostic , Madhur Pathology and Emergency Blood Bank , Gwalior, India
I agree with Carine Temegne Nono
Good question to fallow
1 Recommendation
Gruppo Ricerca Geriatrica, Genova, Italy
Paternity/maternity tests are performed when it is necessary to determine the biological origin of a child.
The test is based on the fact that each person inherits half of their DNA molecules (chromosomes) from their mother, and half – from their father. In order to determine the biological origin of a child, the profiles of DNA molecules of the possible father, the child, and the mother are compared. The DNA profile (STR genotype) is almost unique for each person, since the probability that two males who are not blood relatives might have an identical DNA profile is extremely low. This property of DNA profiles is also used in the paternity test in order to determine the biological origin of a child.
The accuracy of the paternity test is directly proportional to the number of DNA regions (loci) to be tested. In recent history, DNA profiles with 10 DNA loci were compared in paternity tests in Latvia. Today, a DNA profile in which at least 15 DNA loci are compared in samples of a man, a child and a woman is recognised as the best method for proving paternity. Already for the second year GenEra laboratory compares results in 24 loci.The loci to be analysed are determined by international forensic institutions, therefore today almost all laboratories test the same set of loci and the results are often compatible.
Ref.
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University of Baghdad
I think it is not 100 percent accurate because the results of DNA analysis, "The results of the analysis depend on the accuracy of the analysis in terms of sterilization of the laboratory and the absence of bacterial and non-medical factors that can affect the outcome of the analysis, As well as full knowledge of those who are analyzing the steps to be done accurately.
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Government of West Bengal
What is about testing of maternity?
Only Mitochondrial DNA matching?
How it is performed?
Damascus University
A good question to follow, is there no longer a trust among the couples
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Government of West Bengal
Dear colleagues,
I have interest about the scientific aspects only.
As per the laws, so far I know, paternity or maternity information can not be used in personal cases like divorce or inheritance in the court, except the medico- legal cases.
Thanks.
Thanks.
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Bidhan Chandra Krishi Viswavidyalaya (Agricultural Univ)
No specific idea about procedures.....But by following the answers, learnt something.
Regarding the second part of your question, I can have a general opinion based on my personal belief and wisdom. That is ....."No".
2 Recommendations
Narayana Dental College and Hospital
Invasive prenatal paternity testing. It is possible to determine who the biological father of the fetus is while the woman is still pregnant through procedures called chorionic villus sampling or amniocentesis.
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Narayana Dental College and Hospital
Paternity testing can be done by older methods including ABO blood group typing, analysis of various other proteins and enzymes, or using human leukocyte antigen (HLA). However, DNA testing became the only formal and exact method for the paternity testing now. For DNA testing of paternity determination, the DNA collection using an easily obtained cheek swab saliva sample. Fast, proprietary and confidential genetic profiling of the child and alleged father with 99.999% probability/accuracy of results. In the common DNA paternity case, the alleged father and child are tested using polymerase chain reaction (PCR), Short tandem repeat (STR) and restriction fragment length polymorphism (RFLP) methodologies. Results for a DNA paternity case are available in an average of 3-4 days from receipt by the most paternity testing laboratory. Cheek swab saliva testing can be done immediately after birth, and typically the child and alleged father are tested. Results exclude or confirm the biological father with an accuracy rate exceeding 99.9%
for further information please check the pdf
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Austrian Research Centre for Forests
Paternity/maternity EXCLUSION is 100 % (assuming no technical errors in the lab or so), but determination of the "real" parent among some candidates will only get to 99.99999..... % depending on probability
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