Southern Cross University
Question
Asked 3 October 2013
What are saponins and what are their health benefits?
Certain beneficial effect of saponins such as lowering of plasma cholesterol levels in humans, anticarcinogenic activity, inhibitory effect on infectivity of HIV in vitro, antioxidant activity of saponins and protective effect on liver injury. Considerable quantity of soyasaponins are reported in soybean and beans. Soyasaponins are classified into two major groups, soyasaponin A and B. Group A acetylated saponins present in soybean are mostly responsible for undesirable bitter and astringent taste, whereas Group B saponins possess several health benefits. Recent in vitro studies have established that the health benefits such as hypocholesterolemic (cholesterol lowering) effect, anti-carcinogenic, anti-oxidative, anti-tumor, anti-virus, anti-hepatic, anti-diabetic and hepato-protective properties of food legumes are due to presence of group B saponins. Dietary saponins of soybeans are advantageous in preventing hypercholesterolemia and aortic atherosclerosis.
Most recent answer
Thank you Dr. Farhang.
Regards,
Denise Goodfellow
Popular answers (1)
Banaras Hindu University
Saponins are naturally occurring surface active glycosides mainly produced by plants, besides some bacteria and lower marine animals. Their structure consists of a sugar moiety linked to a hydrophobic aglycone called sapogenin. The sugar moiety may contain glucose, galactose, rhamnose, methylpentose, glucuronic acid or xylose, while the aglycone portion may be a steroid or a triterpene. Steroidal saponins are mainly abundant in monocotyledons, while dicotyledons predominantly contain triterpenoid saponins. Saponins may help reduce cholesterol levels, strengthen the immune system, treats diabetes, and inhibit tumor growth. They also improve lipid metabolism and may help prevent and treat obesity. Please see the following RG links for more details.
Article Saponin as anticarcinogens
5 Recommendations
All Answers (10)
Faculty of Agriculture, Menoufia University, Shibin El-Kom, Egypt
Saponins are phytochemicals which can be found in most vegetables, beans and herbs. The best known sources of saponins are peas, soybeans, and some herbs with names indicating foaming properties such as soapwort, saoproot, soapbark and soapberry.
Saponins are glucosides with foaming characteristics. Saponins consist of a polycyclic aglycones attached to one or more sugar side chains. The aglycone part, which is also called sapogenin, is either steroid (C27) or a triterpene (C30). The foaming ability of saponins is caused by the combination of a hydrophobic (fat-soluble) sapogenin and a hydrophilic (water-soluble) sugar part. Saponins have a bitter taste. Some saponins are toxic and are known as sapotoxin.
Health Benefits of Saponins
Saponins cause a reduction of blood cholesterol by preventing its re-absorption.
Saponins have antitumor and anti-mutagenic activities and canlower the risk of human cancers, by preventing cancer cells from growing.
Saponins also seem to help our immune system and to protect against viruses and bacteria.
Saponins have a protective role on bone loss.
The non-sugar part of saponins have a direct antioxidant acitivity, which may results in other benefits such as reduced risk of cancer and heart diseases.
2 Recommendations
Francis Laboratories, c/o SLT Dept, Rivers state Polytechnic
study has also shown that saponins are the active ingredients in certain herbs such as heinsia crinata that mediate the antidiabetic activity of the herb.
Southern Cross University
Saponins are found in some plants used by Aboriginal people for their medicinal properties, for example, Acacia holosericea, A. auriculiformis, and Alphitonia excela.
Banaras Hindu University
Saponins are naturally occurring surface active glycosides mainly produced by plants, besides some bacteria and lower marine animals. Their structure consists of a sugar moiety linked to a hydrophobic aglycone called sapogenin. The sugar moiety may contain glucose, galactose, rhamnose, methylpentose, glucuronic acid or xylose, while the aglycone portion may be a steroid or a triterpene. Steroidal saponins are mainly abundant in monocotyledons, while dicotyledons predominantly contain triterpenoid saponins. Saponins may help reduce cholesterol levels, strengthen the immune system, treats diabetes, and inhibit tumor growth. They also improve lipid metabolism and may help prevent and treat obesity. Please see the following RG links for more details.
Article Saponin as anticarcinogens
5 Recommendations
Central University of Himachal Pradesh
Saponins are strongly bitter-tasting, surface active compounds with a structure consisting of a steroid or triterpenoid aglycone and one or more sugar chains, which are present in quinoa seeds at significant levels.
3 Recommendations
Faculty of Science and Technology, Al-Neelain UniversityAl
Saponins are naturally available compounds that are found in all cells of legume plants. Chemically, saponins contain a carbohydrate part linked to a triterpenoid or steroids.
Benefits of saponin:
1. Reduce risk of cancer
2. Lowering cholesterol level
3. Reduce blood lipid
4. Lowering blood glucose level
5. It is used for inhibition dental caries and
6. It is used for inhibition platelets aggregation
7. It is used as antidote against acute lead poisoning.
Isfahan University of Technology
You could study the following link to get general/overview information about the saponin compound.
1 Recommendation
Similar questions and discussions
Invitation for collaboration and contribution to review papers and research projects in toxicology, pharmacology, and medicinal plants
- Deleted profile
Dear all,
I am writing to invite those colleagues who may be interested in collaborating with me for writing papers in toxicology, pharmacology, and medicinal plants.
Please don't hesitate to contact me via my Gmail address as follows:
Also, you can share your CV, too.
With kindest regards,
Mohammad Amrollahi-Sharifabadi, Ph.D.
Department of Basic Sciences, Faculty of Veterinary Medicine, Lorestan University,
Khorramabad 68151-44316, Iran.
Asst.Prof, Toxicology, https://orcid.org/0000-0002-4458-7689
Related Publications
In den Samen von Digitalis purpurea L. wurden vier Hauptsaponine festgestellt, eines davon enthielt ein bisher unbekanntes Aglykon, das den Namen Digalogenin erhielt. Für dieses konnte die Formel eines 5α.20β.25α‐Spirostan‐diols‐(3β.15β) Nomenklatur nach Fieser.
bewiesen werden.