5th May, 2022
Cardinal Stefan Wyszynski University in Warsaw
Discussion
Started 1st Jun, 2019
What are the applications of bioinformatics in medicine?
Applications of bioinformatics in medicine is a key factor in technological advancement in the field of modern medical technologies.
In which areas of medical technology are the technological achievements of bioinformatics used?
What are the applications of bioinformatics in medicine?
Please reply
I invite you to the discussion
Thank you very much
Best wishes
Most recent answer
Dear Mamoudou Hamadou,
Thanks for the answer. You highlighted important applications of bioinformatics analysis tools in the context of developing new drug research. Simulating the physicochemical and functional properties of molecules is useful for developing new drugs. The combination of bioinformatics and new information technologies ICT and Industry 4.0 generates new possibilities of using bioinformatic analysis tools in the context of the development of modern medical techniques. In the context of the deliberations on the development and application of bioinformatics, I formulated the following research question: To what extent have bioinformatic analysis tools been helpful in the development of SARS-CoV-2 (Covid-19) coronavirus vaccines? What do you think about it?
What is your opinion on this topic?
Please reply,
Thank you very much,
Kind regards,
Dariusz
1 Recommendation
Popular replies (1)
Please have look on our(Eminent Biosciences (EMBS)) collaborations.. and let me know if interested to associate with us
Here is our lab page: https://www.eminentbio.com/home/members
Here is our publication: https://www.eminentbio.com/home/Publication
Our recent publications In collaborations with industries and academia in India and world wide.
Our Lab EMBS's Publication In collaboration with Universidad Tecnológica Metropolitana, Santiago, Chile. Publication Link: https://pubmed.ncbi.nlm.nih.gov/33397265/
Our Lab EMBS's Publication In collaboration with Moscow State University , Russia. Publication Link: https://pubmed.ncbi.nlm.nih.gov/32967475/
Our Lab EMBS's Publication In collaboration with Icahn Institute of Genomics and Multiscale Biology,, Mount Sinai Health System, Manhattan, NY, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29199918
Our Lab EMBS's Publication In collaboration with University of Missouri, St. Louis, MO, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30457050
Our Lab EMBS's Publication In collaboration with Virginia Commonwealth University, Richmond, Virginia, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852211
Our Lab EMBS's Publication In collaboration with ICMR- NIN(National Institute of Nutrition), Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/23030611
Our Lab EMBS's Publication In collaboration with University of Minnesota Duluth, Duluth MN 55811 USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852211
Our Lab EMBS's Publication In collaboration with University of Yaounde I, PO Box 812, Yaoundé, Cameroon. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30950335
Our Lab EMBS's Publication In collaboration with Federal University of Paraíba, João Pessoa, PB, Brazil. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30693065
Our Lab EMBS's Publication In collaboration with collaboration with University of Yaoundé I, Yaoundé, Cameroon. Publication Link: https://pubmed.ncbi.nlm.nih.gov/31210847/
Our Lab EMBS's Publication In collaboration with University of the Basque Country UPV/EHU, 48080, Leioa, Spain. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852204
Our Lab EMBS's Publication In collaboration with King Saud University, Riyadh, Saudi Arabia. Publication Link: http://www.eurekaselect.com/135585
Our Lab EMBS's Publication In collaboration with NIPER , Hyderabad, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29053759
Our Lab EMBS's Publication In collaboration with Alagappa University, Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30950335
Our Lab EMBS's Publication In collaboration with Jawaharlal Nehru Technological University, Hyderabad , India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/28472910
Our Lab EMBS's Publication In collaboration with C.S.I.R – CRISAT, Karaikudi, Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237676
Our Lab EMBS's Publication In collaboration with Karpagam academy of higher education, Eachinary, Coimbatore , Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237672
Our Lab EMBS's Publication In collaboration with Ballets Olaeta Kalea, 4, 48014 Bilbao, Bizkaia, Spain. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29199918
Our Lab EMBS's Publication In collaboration with Hospital for Genetic Diseases, Osmania University, Hyderabad - 500 016, Telangana, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/28472910
Our Lab EMBS's Publication In collaboration with School of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies, Panangad-682 506, Cochin, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27964704
Our Lab EMBS's Publication In collaboration with CODEWEL Nireekshana-ACET, Hyderabad, Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/26770024
Our Lab EMBS's Publication In collaboration with Bharathiyar University, Coimbatore-641046, Tamilnadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27919211
Our Lab EMBS's Publication In collaboration with LPU University, Phagwara, Punjab, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/31030499
Our Lab EMBS's Publication In collaboration with Department of Bioinformatics, Kerala University, Kerala. Publication Link: http://www.eurekaselect.com/135585
Our Lab EMBS's Publication In collaboration with Gandhi Medical College and Osmania Medical College, Hyderabad 500 038, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27450915
Our Lab EMBS's Publication In collaboration with National College (Affiliated to Bharathidasan University), Tiruchirapalli, 620 001 Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27266485
Our Lab EMBS's Publication In collaboration with University of Calicut - 673635, Kerala, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/23030611
Our Lab EMBS's Publication In collaboration with NIPER, Hyderabad, India. ) Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29053759
Our Lab EMBS's Publication In collaboration with King George's Medical University, (Erstwhile C.S.M. Medical University), Lucknow-226 003, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25579575
Our Lab EMBS's Publication In collaboration with School of Chemical & Biotechnology, SASTRA University, Thanjavur, India Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25579569
Our Lab EMBS's Publication In collaboration with Safi center for scientific research, Malappuram, Kerala, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237672
Our Lab EMBS's Publication In collaboration with Dept of Genetics, Osmania University, Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25248957
Our Lab EMBS's Publication In collaboration with Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/26229292
Sincerely,
Dr. Anuraj Nayarisseri
Principal Scientist & Director,
Eminent Biosciences.
Mob :+91 97522 95342
21 Recommendations
All replies (31)
From pediatrics side, Genomictechnologies produces a huge amount of information, unprecedented in biology. Bioinformatics can help to addresse these needs in data acquisition, storage, processing and integration that research in genomics generates.
2 Recommendations
Through combining computer science, mathematics, physics, and biology, Bioinformatics helps us to analyze genome sequence data including human genome data to identify mishaps associated with diseases. It is useful in genomics to characterize and quantify genes, and also in Proteomics, Transcriptomics, Drug Discovery as well as Personalized Medicine.
3 Recommendations
in genomics, proteomics...Scientists in the throes of research use an extensive data bank to access structural information on proteins and nucleic acids. Meanwhile, geneticists use a highly specialized form of software to analyze the hybridization pattern of DNA chips. The past decade has been tremendously successful for biotechnology and pharmaceutical industries. This success has been a result of astounding technical advancements in genome sequencing (genomics), protein identification (proteomics), and data analysis-collectively called bioinformatics ... Rashidi, H. H., & Buehler, L. K. (1999). Bioinformatics basics: applications in biological science and medicine. CRC press.
5 Recommendations
In molecular medicine... Altman, R. B. (1998). Bioinformatics in support of molecular medicine. In Proceedings of the AMIA Symposium (p. 53). American Medical Informatics Association.
5 Recommendations
In precision med... Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small group or even individual patients based on their genetics, environment and lifestyle. Precision medicine relies heavily on developments in systems biology and omics disciplines, including metabolomics. Combination of metabolomics with sophisticated bioinformatics analysis and mathematical modeling has an extreme power to provide a metabolic snapshot of the patient over the course of disease and treatment or classifying patients into subpopulations and subgroups requiring individual medical treatment.... Azad, R. K., & Shulaev, V. (2019). Metabolomics technology and bioinformatics for precision medicine. Briefings in bioinformatics, 20(6), 1957-1971.
5 Recommendations
Bioinformatics will serve to identify susceptibility genes and illuminate the pathogenic pathways involved in illness, and will therefore provide an opportunity for development of targeted therapy. Recently, potential targets in cancers were identified from gene expression profiles. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1122955/
3 Recommendations
As an interdisciplinary field of science, bioinformatics combines biology, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for in silico analyses of biological queries using mathematical and statistical techniques. https://en.m.wikipedia.org/wiki/Bioinformatics
3 Recommendations
The application of bioinformatics is proving quite useful in this field as the human genome has helped unlock the genetic components for many diseases. Potential applications include drug discovery, personalized medicine, preventative medicine and gene therapy. https://www.usfhealthonline.com/resources/key-concepts/what-is-bioinformatics/
3 Recommendations
Bioinformatics applied to the whole genome sequences and their mutations could predict de development of certain type of cancer at a given age. The cybernetic of physiological parameters could also predict the evolution of a given disease. Bioinformatics is also able to test in silico the interaction(s) of given molecules on their targets.
2 Recommendations
Bioinformatics, as a subdiscipline of biology and computer science, is concerned with the acquisition, storage, analysis, and dissemination of biological data, most often DNA and amino acid sequences.
1 Recommendation
Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim of better understanding the genetic basis of disease, unique adaptations, desirable properties...
1 Recommendation
There is a tremendous application of bioinformatics in the field of homology and similarity tools, protein function analysis, personalised medicine, Gene therapy, Drug development, Comparative Studies and also climate change studies. https://www.longdom.org/scholarly/applications-of-bioinformatics-journals-articles-ppts-list-2874.html
1 Recommendation
machine learning-based bioinformatics has been very useful in precision medicine. It can be used for signature-building (based on omics data or a combination of omics and clinical features) to stratify patients for prognosis, drug treatment, early disease detection etc. and biomarker discovery. In order to make machine learning accessible for medical researchers, we have developed a no-code auto-machine learning platform. Our beta version is free, just sign up https://demo.solvergen.com/accounts/login/
1 Recommendation
One key area of bioinformatics is in the area of drug discovery and the areas of bioinformatics needed in drug discovery are molecular docking, molecular dynamics and simulations, free energy calculations and network pharmacology. These are important to save the lives of Laboratory and experimental animals. It is also efficient in saving time and energy.
1 Recommendation
Yes, bioinformatics is currently one of the key determinants of progress in the improvement of medical techniques and therapeutic therapies.
Greetings,
Dariusz Prokopowicz
2 Recommendations
The human genome will have profound implications for biomedical and clinical research. Completion of the human genome and the use of bioinformatics tools means that we can look for genes that are directly related to different diseases and will help to better understand the molecular basis of these diseases. Such new knowledge of molecular mechanisms of disease will enable better treatment, care, and even preventive testing.
1 Recommendation
Dear Jafar Sepahvand,
Thanks for your answer to the question: What are the applications of bioinformatics in medicine?
You have added a significant new perspective on this issue.
Thank you very much,
Greetings,
Dariusz Prokopowicz
3 Recommendations
Please have look on our(Eminent Biosciences (EMBS)) collaborations.. and let me know if interested to associate with us
Here is our lab page: https://www.eminentbio.com/home/members
Here is our publication: https://www.eminentbio.com/home/Publication
Our recent publications In collaborations with industries and academia in India and world wide.
Our Lab EMBS's Publication In collaboration with Universidad Tecnológica Metropolitana, Santiago, Chile. Publication Link: https://pubmed.ncbi.nlm.nih.gov/33397265/
Our Lab EMBS's Publication In collaboration with Moscow State University , Russia. Publication Link: https://pubmed.ncbi.nlm.nih.gov/32967475/
Our Lab EMBS's Publication In collaboration with Icahn Institute of Genomics and Multiscale Biology,, Mount Sinai Health System, Manhattan, NY, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29199918
Our Lab EMBS's Publication In collaboration with University of Missouri, St. Louis, MO, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30457050
Our Lab EMBS's Publication In collaboration with Virginia Commonwealth University, Richmond, Virginia, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852211
Our Lab EMBS's Publication In collaboration with ICMR- NIN(National Institute of Nutrition), Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/23030611
Our Lab EMBS's Publication In collaboration with University of Minnesota Duluth, Duluth MN 55811 USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852211
Our Lab EMBS's Publication In collaboration with University of Yaounde I, PO Box 812, Yaoundé, Cameroon. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30950335
Our Lab EMBS's Publication In collaboration with Federal University of Paraíba, João Pessoa, PB, Brazil. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30693065
Our Lab EMBS's Publication In collaboration with collaboration with University of Yaoundé I, Yaoundé, Cameroon. Publication Link: https://pubmed.ncbi.nlm.nih.gov/31210847/
Our Lab EMBS's Publication In collaboration with University of the Basque Country UPV/EHU, 48080, Leioa, Spain. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852204
Our Lab EMBS's Publication In collaboration with King Saud University, Riyadh, Saudi Arabia. Publication Link: http://www.eurekaselect.com/135585
Our Lab EMBS's Publication In collaboration with NIPER , Hyderabad, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29053759
Our Lab EMBS's Publication In collaboration with Alagappa University, Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30950335
Our Lab EMBS's Publication In collaboration with Jawaharlal Nehru Technological University, Hyderabad , India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/28472910
Our Lab EMBS's Publication In collaboration with C.S.I.R – CRISAT, Karaikudi, Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237676
Our Lab EMBS's Publication In collaboration with Karpagam academy of higher education, Eachinary, Coimbatore , Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237672
Our Lab EMBS's Publication In collaboration with Ballets Olaeta Kalea, 4, 48014 Bilbao, Bizkaia, Spain. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29199918
Our Lab EMBS's Publication In collaboration with Hospital for Genetic Diseases, Osmania University, Hyderabad - 500 016, Telangana, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/28472910
Our Lab EMBS's Publication In collaboration with School of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies, Panangad-682 506, Cochin, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27964704
Our Lab EMBS's Publication In collaboration with CODEWEL Nireekshana-ACET, Hyderabad, Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/26770024
Our Lab EMBS's Publication In collaboration with Bharathiyar University, Coimbatore-641046, Tamilnadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27919211
Our Lab EMBS's Publication In collaboration with LPU University, Phagwara, Punjab, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/31030499
Our Lab EMBS's Publication In collaboration with Department of Bioinformatics, Kerala University, Kerala. Publication Link: http://www.eurekaselect.com/135585
Our Lab EMBS's Publication In collaboration with Gandhi Medical College and Osmania Medical College, Hyderabad 500 038, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27450915
Our Lab EMBS's Publication In collaboration with National College (Affiliated to Bharathidasan University), Tiruchirapalli, 620 001 Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27266485
Our Lab EMBS's Publication In collaboration with University of Calicut - 673635, Kerala, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/23030611
Our Lab EMBS's Publication In collaboration with NIPER, Hyderabad, India. ) Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29053759
Our Lab EMBS's Publication In collaboration with King George's Medical University, (Erstwhile C.S.M. Medical University), Lucknow-226 003, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25579575
Our Lab EMBS's Publication In collaboration with School of Chemical & Biotechnology, SASTRA University, Thanjavur, India Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25579569
Our Lab EMBS's Publication In collaboration with Safi center for scientific research, Malappuram, Kerala, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237672
Our Lab EMBS's Publication In collaboration with Dept of Genetics, Osmania University, Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25248957
Our Lab EMBS's Publication In collaboration with Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/26229292
Sincerely,
Dr. Anuraj Nayarisseri
Principal Scientist & Director,
Eminent Biosciences.
Mob :+91 97522 95342
21 Recommendations
Dear Anuraj Nayarisseri,
Thank you very much for the links to websites and publications that contain interesting materials on the issues of bioinformatics applications in medicine. Thank you very much,
Best regards,
Dariusz Prokopowicz
1 Recommendation
Dear Joan Nyika,
Thanks for the kind words related to this discussion.
Thank you very much,
Regards,
Dariusz Prokopowicz
4 Recommendations
Hi
Bioinformatics analysis tools allow simulations and predictions of the physicochemical and functional properties of molecules.
In medicine, in silico analyses will surely allow predictions of interactions between molecules; the design of new drugs. They can also predict the allergenicity and toxicity of drugs.
Protparam/uniprot/ToxinPred/AllergenFP (plateforms)
1 Recommendation
Dear Mamoudou Hamadou,
Thanks for the answer. You highlighted important applications of bioinformatics analysis tools in the context of developing new drug research. Simulating the physicochemical and functional properties of molecules is useful for developing new drugs. The combination of bioinformatics and new information technologies ICT and Industry 4.0 generates new possibilities of using bioinformatic analysis tools in the context of the development of modern medical techniques. In the context of the deliberations on the development and application of bioinformatics, I formulated the following research question: To what extent have bioinformatic analysis tools been helpful in the development of SARS-CoV-2 (Covid-19) coronavirus vaccines? What do you think about it?
What is your opinion on this topic?
Please reply,
Thank you very much,
Kind regards,
Dariusz
1 Recommendation
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