Breeders use backcross scheme to remove Linkage drag, but in some cases it won't work even after many runs of backcrossing. The remaining 'linkage drag' may have negative impact on the elite lines used to cross with.
There is one molecular technology called 'Site-specific recombination', which can be a useful tool to remove the linkage drag without the tedious process of backcrossing. See attached paper-- see Fig. 5.
Bogor Agricultural University
Amgad A Saleh
King Saud University
Universiti Putra Malaysia
M. C. Sidhu
International Crops Research Institute for Semi Arid Tropics
Abhinandan Surgonda Patil
Agricultural Research Organization ARO
Nuraziawati Mat Yazik
Malaysian Cocoa Board
Ramesh Krishnan Ramasamy
University of California, Davis
Micha Gracianna Devi
Leibniz Institute for Plant Biochemistry
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