Discussion
Started 8th Mar, 2020
  • Independent Academician

How far and how long the world will combat against mutants of SARS-COV-2 ?

1.Virological recombination particularly Indian doubly mutated cases in 2021.
2. South African Omicron variants .
Your participation will be appreciated .
Thanks !

Most recent answer

Popular replies (1)

Dimitri Ketchakmadze
Ilia State University
Reproducible research methods are very important for getting valid/credible research.
"The American Society for Cell Biology (ASCB) has attempted a multi-tiered approach to defining the term reproducibility by identifying the subtle differences in how the term is perceived throughout the scientific community.
ACSB has discussed these differences with the following terms: direct replication, which are efforts to reproduce a previously observed result by using the same experimental design and conditions as the original study; analytic replication, which aims to reproduce a series of scientific findings through a reanalysis of the original data set; systemic replication, which is an attempt to reproduce a published finding under different experimental conditions (e.g., in a different culture system or animal model); and conceptual replication, where the validity of a phenomenon is evaluated using a different set of experimental conditions or methods." https://www.nature.com/articles/d42473-019-00004-y
77 Recommendations

All replies (322)

Jaydip Datta
Independent Academician
Thanks a lot dear
Mila Ilieva
for your excellent remarks !
5 Recommendations
Jaydip Datta
Independent Academician
Reproducible research indicates the feasibility of the Research Experimental Technique - It is applicable for particulary Physico-Chemical , Biological Research
Methodology -rather a checking of significance . The reproducibility means the research is well acceptable / citable .
5 Recommendations
Jaydip Datta
Independent Academician
A Review article may be a kind of Criticality of the Research !
6 Recommendations
Jaydip Datta
Independent Academician
The Reproducibility of Microbial research parameters with statistical relevance
helps the Bio-logical reproducibility of the Experiment .In general biological reproducibility may be difficult w.r .t metabolic pathways , growth kinetics etc .
7 Recommendations
Jaydip Datta
Independent Academician
It does not mean any cut paste or plagiarism issue . It is just a rechecking statistical relevence including chemical process synthesis either improving
kinetics or cost analysis review .
6 Recommendations
Dimitri Ketchakmadze
Ilia State University
Reproducible research methods are very important for getting valid/credible research.
"The American Society for Cell Biology (ASCB) has attempted a multi-tiered approach to defining the term reproducibility by identifying the subtle differences in how the term is perceived throughout the scientific community.
ACSB has discussed these differences with the following terms: direct replication, which are efforts to reproduce a previously observed result by using the same experimental design and conditions as the original study; analytic replication, which aims to reproduce a series of scientific findings through a reanalysis of the original data set; systemic replication, which is an attempt to reproduce a published finding under different experimental conditions (e.g., in a different culture system or animal model); and conceptual replication, where the validity of a phenomenon is evaluated using a different set of experimental conditions or methods." https://www.nature.com/articles/d42473-019-00004-y
77 Recommendations
Jaydip Datta
Independent Academician
Excellent ! I specially appreciate to dear Dimitri Ketchakmadze regarding analytical as well as conceptual rechecking in the field of cell biology .
6 Recommendations
Jaydip Datta
Independent Academician
Reproducible Research thru Statistical data analysis -
7 Recommendations
Jaydip Datta
Independent Academician
Biological Reproducibility of the work :
7 Recommendations
Jaydip Datta
Independent Academician
It is a Statistical Q.C checking of through a review .
7 Recommendations
Jaydip Datta
Independent Academician
6 Recommendations
Jaydip Datta
Independent Academician
6 Recommendations
Jaydip Datta
Independent Academician
6 Recommendations
Jaydip Datta
Independent Academician
In Chemistry also the Reproducible Research is a tuff one particularly depends on
Operating Conditions like Temperature / Pressure / Concentration varition in chemical synthesis w.r.to YIELD !
6 Recommendations
Shurooq Talab Jaafar
AL-Yarmok University College
Reproducible research is the concept that data analyses and the scientific claims are published with their data and software code so that others can assess the results and build upon them.
4 Recommendations
Jaydip Datta
Independent Academician
Dear Dr. Shurooq Talab Jaafar - Thanks for response .
6 Recommendations
Qusay Kh. Al-Dulamey
University of Mosul
Repeating anything in the same way and that in the purpose weakens the research, but to use it in a new topic is excellent, this is my view
4 Recommendations
Muhammad Ali
Charles Sturt University
Deep learning is a recent live such example for various type of reproducibility of AI techniques.
2 Recommendations
Jaydip Datta
Independent Academician
Dear Dr. @ Qusay_Al-Dulamey thanks for your response to let us know your point of view .
6 Recommendations
Jaydip Datta
Independent Academician
Thanks to Dr. Muhammad Ali for your view towards Deep learning & reproducible Research .
7 Recommendations
Jaydip Datta
Independent Academician
Reproducible research & Corona virus -
6 Recommendations
Jaydip Datta
Independent Academician
Jaydip Datta
Independent Academician
During 3D - QSAR technique in molecular drug design this technique is most important for drug developement .
6 Recommendations
Jaydip Datta
Independent Academician
Whether Viral Mutation is reproducible ?
6 Recommendations
Jaydip Datta
Independent Academician
Mass Spectroscopic study of Corona Virus - Reproducible research / not .
5 Recommendations
Jaydip Datta
Independent Academician
Actually log /exponential phase of corona virus too much sharp to reproducible
thas why the spreading is very quick .
7 Recommendations
Jaydip Datta
Independent Academician
Reproducible Research Technique of Covid 19 .
7 Recommendations
Amjed L. Jabbar
University of Diyala
a tremendous variety of scientific sources (free) on the covid19 pandemic
3 Recommendations
Jaydip Datta
Independent Academician
Excellent source dear Amjed L. Jabbar - one of the most important from it is
9 Recommendations
Amjed L. Jabbar
University of Diyala
Jaydip Datta, thanks for your source dear sir.
3 Recommendations
Jaydip Datta
Independent Academician
You are most welcome dear Amjed L. Jabbar on my other queries /dicussion also ( 80 Nos ) .You are requested to go through for response .
8 Recommendations
Eman Riyadh Adeeb
University of Diyala
Really so beneficial comments and sites exchanges thanks a lot Dr.Jaydip.
3 Recommendations
Jaydip Datta
Independent Academician
Dear Eman Riyadh Adeeb thanks for your realisation .
7 Recommendations
Eman Riyadh Adeeb
University of Diyala
Thanks Dr.Jaydip.
4 Recommendations
Jaydip Datta
Independent Academician
To attempt the reproducibility of the research we can optimization method depending upon the real life data of statistics then economic theory of optimisation .
5 Recommendations
Jaydip Datta
Independent Academician
First of all we have to collect the exact data like number of death , the exponentiallity of Viral infection , Lockdown period of a specific region and then the best fit statistics may be correlated with optimisation theory through break even point analysis .
6 Recommendations
Jaydip Datta
Independent Academician
7 Recommendations
Jaydip Datta
Independent Academician
But Reproducible Research will help us to detect the type of Mutation of Covid19 -
8 Recommendations
Dear Jaydip Datta
Very very nice and creative work.
Good Job.
Best regards
2 Recommendations
Dear Dimitri Ketchakmadze
Very very nice contribution
Best regards
1 Recommendation
Jaydip Datta
Independent Academician
Except lethal rate / death rate nothing is reported to reproduce due to highly spreading Covid19 mutants or genetic recombination .
6 Recommendations
Good discussion
1 Recommendation
Following
1 Recommendation
Mourad Aty
University of Porto
Interesting !
1 Recommendation
Jaydip Datta
Independent Academician
Reproducible Research Technique in Covid19 -https://www.researchgate.net/deref/https%3A%2F%2Fosf.io%2Fad9pe%2F
( It is available in Corona Virus Outbreak Research )
6 Recommendations
Jaydip Datta
Independent Academician
Reproducible Research indicates a good result ie Remedesivir - A potent drug against Corona Virus is available in India licenced by world trade corporation .
6 Recommendations
Jaydip Datta
Independent Academician
This type of research technique is highly important at the failure stage of veccine developement . The effect analysis .
5 Recommendations
Jaydip Datta
Independent Academician
Jaydip Datta
Independent Academician
Dexamethasone is reported as ist drug which can reduce death rate - REF : Nature
Briefing .
6 Recommendations
Jaydip Datta
Independent Academician
Structure of Dexamethasone - the key of Clinical activity -
REF :chemspider.com ( Image Source ) .
6 Recommendations
Jaydip Datta
Independent Academician
It is a research hub for infectious diseases like covid19 , Immunology , reproducibility , culture microbiology - https://www.the-scientist.com/tag/reproducibility,immunology,culture,microbiology
6 Recommendations
Jaydip Datta
Independent Academician
COVAXINE - An attempt by ICMR but reproducibility /relability testing has not started yet by animal trial - https://indianexpress.com/article/india/icmr-claim-coronavirus-vaccine-covid-cure-6489171/
6 Recommendations
Jaydip Datta
Independent Academician
Reliability testing and reproducibility of Vaccine trial -
5 Recommendations
Jaydip Datta
Independent Academician
Saliva - The most relable tool for reproducibility testing -https://pubmed.ncbi.nlm.nih.gov/32298676/
6 Recommendations
Christian G Meyer
Physician; independent researcher / consultant - infectious disease specialist - editor
What is a "relable tool"?
5 Recommendations
Jaydip Datta
Independent Academician
Great Query - Please put this in RG Question / Answer session ! How much recommendations have you expected to such query -Christian G Meyer
7 Recommendations
Jaydip Datta
Independent Academician
You can take a short course on Reproducable Research from this thread in reference of this particular query -https://www.researchgate.net/deref/https%3A%2F%2Fwww.nceas.ucsb.edu%2Flearning-hub%2Fshort-course
7 Recommendations
Jaydip Datta
Independent Academician
Jaydip Datta
Independent Academician
Jaydip Datta
Independent Academician
Bat Corona Virus - Another name of Immunology - A surprising news ! - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=672e88663e&e=5944515236
7 Recommendations
Jaydip Datta
Independent Academician
SARS - COV-2 was active for last 40-60 Yrs within Bats !
6 Recommendations
Jaydip Datta
Independent Academician
Chinese Vaccines are all in Phase III trials -needed to Prove Therapeutic index - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=61f3a909f8&e=5944515236
7 Recommendations
Jaydip Datta
Independent Academician
Scientists observed to play all the parts of Immune system in a harmonic way -"https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=8c4db46dce&e=5944515236 "
7 Recommendations
Jaydip Datta
Independent Academician
From Preliminary Research a Pregnant woman is more suseptable towards Covid infection - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=e9f92106ac&e=5944515236
6 Recommendations
Jaydip Datta
Independent Academician
The Serum Institute of India and Oxford University - Joint gamble to Vaccine Reseaerch - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=a2d022f990&e=5944515236
5 Recommendations
Jaydip Datta
Independent Academician
" https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=d3626baef6&e=5944515236 " - Failure to tackale Corona reproducibility in cold weather as per Epidemologist Michael Mina .
6 Recommendations
Jaydip Datta
Independent Academician
" https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=7426bd1473&e=5944515236 " - by Infectious disese speciliased researcher Rita Colwell of U.S .
6 Recommendations
Jaydip Datta
Independent Academician
The most important part of reliability study - Randomized Control trial test about safety and clinical effectiveness of Covid19 - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=2ae67ba1fa&e=5944515236
6 Recommendations
Jaydip Datta
Independent Academician
6 Recommendations
Jaydip Datta
Independent Academician
Along with Covid infection the TB , AIDS , Malaria are resurging . What will be the remedies ? - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=22b083ee46&e=5944515236
7 Recommendations
Jaydip Datta
Independent Academician
We all should acknowledge stem-cell biologist Prabha Devan for his dedication towards her 7 Yrs Child to combine an attempt towards Research . But how misarable is Covid19 lockdown - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=701de9e972&e=5944515236
7 Recommendations
Jaydip Datta
Independent Academician
5 Recommendations
Jaydip Datta
Independent Academician
Challanges of Matthew Duchars , CEO of U.K vaccine production centre in large scale - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=f0b734c7c1&e=5944515236
5 Recommendations
Jaydip Datta
Independent Academician
The protein layer on the capsule of SARS-COV-2 will geterate a new coronavirus 2
6 Recommendations
Jaydip Datta
Independent Academician
SARS-COV-2 is structurally similar to SARS-COV -
6 Recommendations
Jaydip Datta
Independent Academician
Jaydip Datta
Independent Academician
Infection Fatality Ratio is nil in case of younger people but it is > 50 Yrs & above - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=babcff9852&e=5944515236
5 Recommendations
Jaydip Datta
Independent Academician
More Important Information from Age & Sex of spreading of infection - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=2f3ddd0d73&e=5944515236
5 Recommendations
Jaydip Datta
Independent Academician
A Very Important paper regarding Fatality Infection Ratio w.r.t age & sex is -medRxiv1-3 & Lancet Infectious Diseases paper - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=81f5f223b0&e=5944515236
5 Recommendations
Jaydip Datta
Independent Academician
More Speect from Marm Kilpatrick ( An ID Researcher ) - Death or Long Time Illness due to Covid19 - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=5c385c696b&e=5944515236
5 Recommendations
Jaydip Datta
Independent Academician
Excess of more than 85,000 have died in Covid19 - The datasets of EU - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=9c494422bd&e=5944515236
4 Recommendations
Jaydip Datta
Independent Academician
More death than expected - REF : nature.com ( Copyright )
4 Recommendations
Jaydip Datta
Independent Academician
NIH does not warrent to recover from Covid19 by convulescent plasma therapy - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=5fc39912ba&e=5944515236
4 Recommendations
Jaydip Datta
Independent Academician
The Gold -standard trial with a large number of recovery are going on U.K - https://nature.us17.list-manage.com/track/click?u=2c6057c528fdc6f73fa196d9d&id=ce9facdafd&e=5944515236
4 Recommendations

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