How can we purchase psilocybin for human pilot study?

As often in medicine animals are ( SADLY) used in experiments .A new study of mice shows there are important links between human and mouse minds in how they function -- and malfunction. Researchers at Washington University School of Medicine in St. Louis devised a rigorous approach to study how hallucinations are produced in the brain, providing a promising entry point to the development of much-needed new therapies for schizophrenia.

The study that was published in the journal Science, lays out a way to probe the biological roots of a defining symptom of psychosis: hallucinations. The researchers trained people and mice to complete a computer-based task that induced them to hear imaginary sounds. By analyzing performance of the task, the researchers were able to objectively measure hallucination-like events in people and mice.

This approach allowed them to study the neural circuits underlying hallucinations, potentially fully opening up the study of mental illness to the kind of scientific studies that have been fruitful for diseases of other parts of the body. My concern is that despite the positives and even if there are similarities, can a study like this be of great value when it comes to humans who has a fundamentally different cognitive ability and brain structure? I agree that we can see tendencies and the study gives an insight, however can this ever fully be transferred to humans? also see other risks as well as grave ethical concerns that applies with all experiments on animals. What are your thoughts?

Best wishes

Henrik

A patient suffering from psychotic disorder treated with low dose clozapine (150mg/day) experienced a very high, asymptomatic raises of serum CPK (up to 40 000). No symptoms of neuroleptic malignant syndrome. Any suggestions?

articles and books relevant to fear in psychiatric patients, especially if there is evidence that compares psychiatric patients and mentally healthy people about the feeling of fear.

I am looking at the debate about whether DID exists and whether it is ethical to take the disorder out of the DSM-V.

Why do you think such links exist?

Has anyone ever seen a finding where people with schizophrenia perform more abnormally (on a cognitive or perceptual task) when stabilizing, compared to when they are acutely psychotic? I just completed a study where it looks like patients perform normally at hospital admission, abnormally at hospital discharge, and then normally again several months later. This doesn't seem to be an artifact (and it is replicated across multiple task conditions) but I have never seen a result like this before. The task is a visual perception task that involves integration of information and then an illusion effect.  Any suggestions will be greatly appreciated! Thanks, Steve

Is the Pregabalin therapy the most effective type of pharmacotherapy for a generalized anxiety disorder?